RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Transmemebrane
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000111801	Gene ID	10384	Accession	1140
Symbol	BTN3A3	Alias	BTF3;BTN3.3	Full Name	butyrophilin subfamily 3 member A3
Status	Confidence	Length	12944 bases	Strand	Plus strand
Position	6 : 26440472 - 26453415	RNA binding domain	SPRY
Summary	The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000355238	SPRY	PF00622	8.7e-18	1
ENSP00000244519	SPRY	PF00622	1e-17	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
44131	Platelet Function Tests	2.2932300E-005	-
44134	Platelet Function Tests	2.2932300E-005	-
44152	Platelet Function Tests	2.2932300E-005	-
44154	Platelet Function Tests	2.3041100E-005	-
44349	Platelet Function Tests	1.7106600E-005	-
44352	Platelet Function Tests	1.7106600E-005	-
44369	Platelet Function Tests	1.7106600E-005	-
44371	Platelet Function Tests	1.7188100E-005	-
45485	Platelet Function Tests	1.0221100E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001817	involved_in regulation of cytokine production	1	IBA	Homo_sapiens(9606)	Process
GO:0002456	involved_in T cell mediated immunity	1	IMP	Homo_sapiens(9606)	Process
GO:0005102	enables signaling receptor binding	1	IBA	Homo_sapiens(9606)	Function
GO:0005886	located_in plasma membrane	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0009897	is_active_in external side of plasma membrane	1	IBA	Homo_sapiens(9606)	Component
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0050852	involved_in T cell receptor signaling pathway	1	IBA	Homo_sapiens(9606)	Process