RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000110871	Gene ID	84274	Accession	28722
Symbol	COQ5	Alias	COQ10D9	Full Name	coenzyme Q5, methyltransferase
Status	Confidence	Length	31156 bases	Strand	Minus strand
Position	12 : 120503279 - 120534434	RNA binding domain	Methyltransf_31
Summary	Enables 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity. Involved in methylation and ubiquinone biosynthetic process. Located in mitochondrial matrix. Part of protein-containing complex. Colocalizes with mitochondrial inner membrane. Implicated in primary coenzyme Q10 deficiency 9. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000449863	Methyltransf_31	PF13847	1.6e-12	1
ENSP00000288532	Methyltransf_31	PF13847	3.7e-12	1
ENSP00000401798	Methyltransf_31	PF13847	3.4e-06	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
COQ5-201	ENST00000288532	1506	327aa	ENSP00000288532
COQ5-202	ENST00000445328	992	253aa	ENSP00000401798
COQ5-208	ENST00000552443	972	213aa	ENSP00000449863
COQ5-203	ENST00000546838	391	No protein	-
COQ5-206	ENST00000547943	552	176aa	ENSP00000449874
COQ5-207	ENST00000551769	560	130aa	ENSP00000450001
COQ5-205	ENST00000547736	574	91aa	ENSP00000449933
COQ5-204	ENST00000547448	701	No protein	-

Gene Model

Click here to download ENSG00000110871's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000110871's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005743	colocalizes_with mitochondrial inner membrane	2	IDA	Homo_sapiens(9606)	Component
GO:0005759	located_in mitochondrial matrix	1	IDA	Homo_sapiens(9606)	Component
GO:0006744	involved_in ubiquinone biosynthetic process	4	IBA,IEA,IGI,NAS	Homo_sapiens(9606)	Process
GO:0008168	enables methyltransferase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0031314	located_in extrinsic component of mitochondrial inner membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0032259	involved_in methylation	1	IDA	Homo_sapiens(9606)	Process
GO:0032991	part_of protein-containing complex	1	IDA	Homo_sapiens(9606)	Component
GO:0043333	enables 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0043430	enables 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0110142	part_of ubiquinone biosynthesis complex	1	IPI	Homo_sapiens(9606)	Component

Expression