Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq DataSet_01_163 DataSet_01_469 DataSet_02_25 DataSet_02_26 DataSet_02_27 DataSet_02_28 DataSet_02_35 DataSet_02_36

Description

Ensembl ID ENSG00000110367 Gene ID 1656 Accession 2747
Symbol DDX6 Alias P54;RCK;HLR2;IDDILF;Rck/p54 Full Name DEAD-box helicase 6
Status Confidence Length 43402 bases Strand Minus strand
Position 11 : 118747763 - 118791164 RNA binding domain DEAD
Summary This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Transcripts

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression