RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000110090	Gene ID	1374	Accession	2328
Symbol	CPT1A	Alias	CPT1;CPT1-L;L-CPT1	Full Name	carnitine palmitoyltransferase 1A
Status	Confidence	Length	89791 bases	Strand	Minus strand
Position	11 : 68754620 - 68844410	RNA binding domain	N.A.
Summary	The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
CPT1A-206	ENST00000540367	2496	756aa	ENSP00000439084
CPT1A-202	ENST00000376618	2635	756aa	ENSP00000365803
CPT1A-201	ENST00000265641	5238	773aa	ENSP00000265641
CPT1A-205	ENST00000539743	2382	773aa	ENSP00000446108
CPT1A-203	ENST00000537756	585	No protein	-
CPT1A-204	ENST00000538994	617	78aa	ENSP00000454332
CPT1A-208	ENST00000565318	511	134aa	ENSP00000457826
CPT1A-209	ENST00000569129	499	117aa	ENSP00000455116
CPT1A-207	ENST00000561996	559	93aa	ENSP00000457663

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
26337	Arteries	3.7500000E-005	-
40178	Platelet Function Tests	5.2300000E-006	-
48104	Autistic Disorder	1.3578000E-005	-
49810	Child Development Disorders, Pervasive	5.6331200E-005	-
50426	Child Development Disorders, Pervasive	1.7345000E-005	-
51854	Child Development Disorders, Pervasive	2.2193000E-005	-
72960	Energy Metabolism	4E-6	23251661

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001676	involved_in long-chain fatty acid metabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0004095	enables carnitine O-palmitoyltransferase activity	4	IBA,IDA,IMP,TAS	Homo_sapiens(9606)	Function
GO:0005739	is_active_in mitochondrion	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005741	located_in mitochondrial outer membrane	3	IMP,ISS,TAS	Homo_sapiens(9606)	Component
GO:0006006	involved_in glucose metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006631	involved_in fatty acid metabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0006635	involved_in fatty acid beta-oxidation	1	IEA	Homo_sapiens(9606)	Process
GO:0006641	involved_in triglyceride metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006853	involved_in carnitine shuttle	1	TAS	Homo_sapiens(9606)	Process
GO:0009410	involved_in response to xenobiotic stimulus	1	IEA	Homo_sapiens(9606)	Process
GO:0009437	involved_in carnitine metabolic process	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0010883	involved_in regulation of lipid storage	1	IEA	Homo_sapiens(9606)	Process
GO:0014070	involved_in response to organic cyclic compound	1	IEA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0030855	involved_in epithelial cell differentiation	1	IEP	Homo_sapiens(9606)	Process
GO:0031667	involved_in response to nutrient levels	1	IEA	Homo_sapiens(9606)	Process
GO:0032000	involved_in positive regulation of fatty acid beta-oxidation	1	IEA	Homo_sapiens(9606)	Process
GO:0042755	involved_in eating behavior	1	IEA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IEA	Homo_sapiens(9606)	Function
GO:0043279	involved_in response to alkaloid	1	IEA	Homo_sapiens(9606)	Process
GO:0045471	involved_in response to ethanol	1	IEA	Homo_sapiens(9606)	Process
GO:0050796	involved_in regulation of insulin secretion	1	IEA	Homo_sapiens(9606)	Process
GO:0071398	involved_in cellular response to fatty acid	1	IEA	Homo_sapiens(9606)	Process
GO:0097421	involved_in liver regeneration	1	IEA	Homo_sapiens(9606)	Process
GO:1904772	involved_in response to tetrachloromethane	1	IEA	Homo_sapiens(9606)	Process
GO:1990698	enables palmitoleoyltransferase activity	1	IEA	Homo_sapiens(9606)	Function