RBP Type
Non-canonical_RBPs
Diseases
Disease
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000108559 Gene ID
4927
Accession
8067
Symbol
NUP88
Alias
FADS4
Full Name
nucleoporin 88
Status
Confidence
Length
60497 bases
Strand
Minus strand
Position
17 : 5359668 - 5420164
RNA binding domain
N.A.
Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
NUP88-214
ENST00000700529
4626
732aa
ENSP00000515034
NUP88-206
ENST00000573169
1195
No protein
-
NUP88-212
ENST00000576708
800
110aa
ENSP00000461334
NUP88-215
ENST00000700530
2270
657aa
ENSP00000515035
NUP88-216
ENST00000700531
5220
711aa
ENSP00000515036
NUP88-217
ENST00000700532
5185
699aa
ENSP00000515037
NUP88-218
ENST00000700533
5175
368aa
ENSP00000515038
NUP88-219
ENST00000700534
5235
441aa
ENSP00000515039
NUP88-220
ENST00000700535
5246
712aa
ENSP00000515040
NUP88-221
ENST00000700536
5283
169aa
ENSP00000515041
NUP88-222
ENST00000700537
5253
449aa
ENSP00000515042
NUP88-203
ENST00000572019
5474
151aa
ENSP00000515043
NUP88-223
ENST00000700538
5682
721aa
ENSP00000515044
NUP88-224
ENST00000700539
3329
435aa
ENSP00000515045
NUP88-225
ENST00000700540
3683
475aa
ENSP00000515046
NUP88-226
ENST00000700541
3465
368aa
ENSP00000515047
NUP88-227
ENST00000700542
3549
704aa
ENSP00000515048
NUP88-228
ENST00000700543
3534
688aa
ENSP00000515049
NUP88-201
ENST00000225696
3900
757aa
ENSP00000225696
NUP88-207
ENST00000573584
3611
741aa
ENSP00000458954
NUP88-229
ENST00000700544
3438
610aa
ENSP00000515050
NUP88-230
ENST00000700545
2909
229aa
ENSP00000515051
NUP88-209
ENST00000574855
434
No protein
-
NUP88-231
ENST00000700546
2023
646aa
ENSP00000515052
NUP88-208
ENST00000574087
548
No protein
-
NUP88-213
ENST00000576862
788
No protein
-
NUP88-211
ENST00000575976
599
No protein
-
NUP88-210
ENST00000574867
2081
No protein
-
NUP88-202
ENST00000570937
2671
98aa
ENSP00000515053
NUP88-232
ENST00000700547
2346
No protein
-
NUP88-233
ENST00000700548
321
No protein
-
NUP88-205
ENST00000572809
771
153aa
ENSP00000459370
NUP88-204
ENST00000572290
615
128aa
ENSP00000459979
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000055 involved_in ribosomal large subunit export from nucleus 1 IBA Homo_sapiens(9606) Process GO:0000056 involved_in ribosomal small subunit export from nucleus 1 IBA Homo_sapiens(9606) Process GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005635 located_in nuclear envelope 1 IDA Homo_sapiens(9606) Component GO:0005643 part_of nuclear pore 3 IBA,IDA,NAS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005829 located_in cytosol 1 TAS Homo_sapiens(9606) Component GO:0006406 involved_in mRNA export from nucleus 1 IBA Homo_sapiens(9606) Process GO:0006606 involved_in protein import into nucleus 1 IBA Homo_sapiens(9606) Process GO:0006913 involved_in nucleocytoplasmic transport 1 NAS Homo_sapiens(9606) Process GO:0017056 enables structural constituent of nuclear pore 1 IEA Homo_sapiens(9606) Function
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