Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVFlavivirusesHIVIAVSARS-COV-2SINVDengue
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions Metabolic enzyme
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000108424 Gene ID 3837 Accession 6400
Symbol KPNB1 Alias IMB1;IPO1;IPOB;Impnb;NTF97 Full Name karyopherin subunit beta 1
Status Confidence Length 36030 bases Strand Plus strand
Position 17 : 47649476 - 47685505 RNA binding domain IBN_N
Summary Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000290158 IBN_N PF03810 2.9e-11 1
ENSP00000464042 IBN_N PF03810 2.9e-11 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32413045 Mutation severity spectrum of rare alleles in the human genome is predictive of disease type. Jimin Pei 2020-05-01 PLoS computational biology
26791949 Host gene expression classifiers diagnose acute respiratory illness etiology. L Ephraim Tsalik 2016-01-20 Science translational medicine

Transcripts

Name Transcript ID bp Protein Translation ID
KPNB1-202 ENST00000535458 3163 731aa ENSP00000438253
KPNB1-214 ENST00000583648 6182 876aa ENSP00000464042
KPNB1-201 ENST00000290158 6058 876aa ENSP00000290158
KPNB1-205 ENST00000577918 859 No protein -
KPNB1-204 ENST00000577875 605 60aa ENSP00000464200
KPNB1-203 ENST00000540627 2989 731aa ENSP00000438964
KPNB1-211 ENST00000582097 2347 690aa ENSP00000463066
KPNB1-215 ENST00000677036 1216 No protein -
KPNB1-213 ENST00000583013 742 248aa ENSP00000463190
KPNB1-216 ENST00000677341 2197 No protein -
KPNB1-207 ENST00000579901 594 No protein -
KPNB1-206 ENST00000578718 550 No protein -
KPNB1-208 ENST00000580019 427 No protein -
KPNB1-210 ENST00000580573 2087 No protein -
KPNB1-209 ENST00000580158 3338 No protein -
KPNB1-212 ENST00000582126 653 22aa ENSP00000462243

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
85542Optic Disk2E-825631615
90317Optic Disk2E-825631615
94643Multiple Sclerosis1E-722190364
103995Spondylitis, Ankylosing5E-821743469

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000108424homo_sapiensENSP0000034645330.342316.3737homo_sapiensENSP0000029015837.442920.2055
ENSG00000108424homo_sapiensENSP0000040718227.313312.5975homo_sapiensENSP0000029015827.96812.8995
ENSG00000108424homo_sapiensENSP0000049912529.170514.1294homo_sapiensENSP0000029015836.529717.6941
ENSG00000108424homo_sapiensENSP0000033671227.616913.6971homo_sapiensENSP0000029015828.310514.0411
ENSG00000108424homo_sapiensENSP0000025956928.235313.3032homo_sapiensENSP0000029015835.616416.7808

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000108424homo_sapiensENSP00000290158100100nomascus_leucogenysENSNLEP00000001948100100
ENSG00000108424homo_sapiensENSP00000290158100100pan_paniscusENSPPAP00000011352100100
ENSG00000108424homo_sapiensENSP00000290158100100pongo_abeliiENSPPYP00000023559100100
ENSG00000108424homo_sapiensENSP00000290158100100pan_troglodytesENSPTRP00000015867100100
ENSG00000108424homo_sapiensENSP00000290158100100gorilla_gorillaENSGGOP00000007915100100
ENSG00000108424homo_sapiensENSP0000029015898.744397.9452ornithorhynchus_anatinusENSOANP0000000854698.744397.9452
ENSG00000108424homo_sapiensENSP0000029015899.543498.516sarcophilus_harrisiiENSSHAP0000002150199.543498.516
ENSG00000108424homo_sapiensENSP0000029015893.835692.8082notamacropus_eugeniiENSMEUP0000001305193.942992.9143
ENSG00000108424homo_sapiensENSP0000029015863.356263.0137choloepus_hoffmanniENSCHOP0000000939064.760864.4107
ENSG00000108424homo_sapiensENSP0000029015879.109678.653dasypus_novemcinctusENSDNOP0000001128499.56998.9943
ENSG00000108424homo_sapiensENSP0000029015880.13779.4521erinaceus_europaeusENSEEUP0000000463683.27482.5623
ENSG00000108424homo_sapiensENSP0000029015854.223753.653echinops_telfairiENSETEP0000000358860.741760.1023
ENSG00000108424homo_sapiensENSP0000029015810099.8858callithrix_jacchusENSCJAP0000001471310099.8858
ENSG00000108424homo_sapiensENSP00000290158100100cercocebus_atysENSCATP00000027564100100
ENSG00000108424homo_sapiensENSP0000029015899.771799.7717macaca_fascicularisENSMFAP00000014277100100
ENSG00000108424homo_sapiensENSP0000029015897.716997.7169macaca_mulattaENSMMUP00000025988100100
ENSG00000108424homo_sapiensENSP00000290158100100macaca_nemestrinaENSMNEP00000035729100100
ENSG00000108424homo_sapiensENSP00000290158100100papio_anubisENSPANP00000020466100100
ENSG00000108424homo_sapiensENSP0000029015897.374496.9178mandrillus_leucophaeusENSMLEP0000002825597.597397.1396
ENSG00000108424homo_sapiensENSP0000029015895.776395.5479tursiops_truncatusENSTTRP0000000442399.525599.2883
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292vulpes_vulpesENSVVUP0000000393499.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.771799.2009mus_spretusMGP_SPRETEiJ_P003093299.431298.8623
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292equus_asinusENSEASP0000500094299.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292capra_hircusENSCHIP0000001355699.543999.3158
ENSG00000108424homo_sapiensENSP0000029015895.776394.0639loxodonta_africanaENSLAFP0000000111896.105494.3872
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292panthera_leoENSPLOP0000000797499.657599.4292
ENSG00000108424homo_sapiensENSP0000029015895.890495.6621ailuropoda_melanoleucaENSAMEP0000000490497.447897.2158
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292bos_indicus_hybridENSBIXP0000502775099.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.885899.4292oryctolagus_cuniculusENSOCUP0000001325899.885899.4292
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292equus_caballusENSECAP0000006070395.934195.7143
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292canis_lupus_familiarisENSCAFP0084502139499.657599.4292
ENSG00000108424homo_sapiensENSP0000029015897.146196.2329panthera_pardusENSPPRP0000000325197.703896.7853
ENSG00000108424homo_sapiensENSP0000029015896.004695.6621marmota_marmota_marmotaENSMMMP0000002318899.762799.4069
ENSG00000108424homo_sapiensENSP0000029015899.543499.3151balaenoptera_musculusENSBMSP0001002965299.543499.3151
ENSG00000108424homo_sapiensENSP0000029015899.657599.0868cavia_porcellusENSCPOP0000002615199.657599.0868
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292felis_catusENSFCAP0000001908999.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292ursus_americanusENSUAMP0000003325099.543999.3158
ENSG00000108424homo_sapiensENSP0000029015899.429298.4018monodelphis_domesticaENSMODP0000005299599.315898.2896
ENSG00000108424homo_sapiensENSP0000029015897.374497.1461bison_bison_bisonENSBBBP0000001436597.374497.1461
ENSG00000108424homo_sapiensENSP0000029015899.543499.3151monodon_monocerosENSMMNP0001502345199.543499.3151
ENSG00000108424homo_sapiensENSP0000029015899.543499.2009sus_scrofaENSSSCP0000001856299.543499.2009
ENSG00000108424homo_sapiensENSP0000029015899.771799.6575microcebus_murinusENSMICP0000001098183.877283.7812
ENSG00000108424homo_sapiensENSP0000029015899.657598.7443octodon_degusENSODEP0000002360499.657598.7443
ENSG00000108424homo_sapiensENSP0000029015899.771799.0868jaculus_jaculusENSJJAP0000000618999.771799.0868
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292ovis_aries_rambouilletENSOARP0002002578499.657599.4292
ENSG00000108424homo_sapiensENSP0000029015897.146196.2329ursus_maritimusENSUMAP0000002292695.510794.6128
ENSG00000108424homo_sapiensENSP0000029015890.867690.5251ochotona_princepsENSOPRP0000000351292.773992.4242
ENSG00000108424homo_sapiensENSP0000029015899.543499.3151delphinapterus_leucasENSDLEP0000000565799.429999.2018
ENSG00000108424homo_sapiensENSP0000029015875.456675.2283physeter_catodonENSPCTP0000500737499.548299.247
ENSG00000108424homo_sapiensENSP0000029015893.607393.0365mus_caroliMGP_CAROLIEiJ_P002951299.756799.1484
ENSG00000108424homo_sapiensENSP0000029015899.771799.2009mus_musculusENSMUSP0000000147999.771799.2009
ENSG00000108424homo_sapiensENSP0000029015899.086898.516mustela_putorius_furoENSMPUP0000001511198.973898.4036
ENSG00000108424homo_sapiensENSP0000029015894.063992.3516aotus_nancymaaeENSANAP0000003524696.713694.953
ENSG00000108424homo_sapiensENSP0000029015897.488697.2603aotus_nancymaaeENSANAP0000001406798.957198.7254
ENSG00000108424homo_sapiensENSP00000290158100100saimiri_boliviensis_boliviensisENSSBOP0000002737994.294994.2949
ENSG00000108424homo_sapiensENSP0000029015885.27484.589vicugna_pacosENSVPAP0000000341186.658985.9629
ENSG00000108424homo_sapiensENSP00000290158100100chlorocebus_sabaeusENSCSAP00000015441100100
ENSG00000108424homo_sapiensENSP0000029015879.223779.1096tupaia_belangeriENSTBEP0000000914595.198995.0617
ENSG00000108424homo_sapiensENSP0000029015899.771799.3151mesocricetus_auratusENSMAUP0000000467899.771799.3151
ENSG00000108424homo_sapiensENSP0000029015899.543499.3151phocoena_sinusENSPSNP0000002601899.543499.3151
ENSG00000108424homo_sapiensENSP0000029015899.543499.0868camelus_dromedariusENSCDRP0000502769299.543499.0868
ENSG00000108424homo_sapiensENSP0000029015897.716997.3744carlito_syrichtaENSTSYP0000001329398.959598.6127
ENSG00000108424homo_sapiensENSP0000029015897.146196.2329panthera_tigris_altaicaENSPTIP0000000437797.703896.7853
ENSG00000108424homo_sapiensENSP0000029015899.771799.2009rattus_norvegicusENSRNOP0000001237699.771799.2009
ENSG00000108424homo_sapiensENSP0000029015899.771799.6575prolemur_simusENSPSMP0000001087499.657999.5439
ENSG00000108424homo_sapiensENSP0000029015899.771799.3151microtus_ochrogasterENSMOCP0000000444799.771799.3151
ENSG00000108424homo_sapiensENSP0000029015876.48476.0274sorex_araneusENSSARP0000000136576.571476.1143
ENSG00000108424homo_sapiensENSP0000029015899.771799.3151peromyscus_maniculatus_bairdiiENSPEMP0000001951499.771799.3151
ENSG00000108424homo_sapiensENSP0000029015895.890495.6621bos_mutusENSBMUP0000000117595.890495.6621
ENSG00000108424homo_sapiensENSP0000029015899.771799.2009mus_spicilegusENSMSIP0000002119299.771799.2009
ENSG00000108424homo_sapiensENSP0000029015899.771799.3151cricetulus_griseus_chok1gshdENSCGRP0000101543399.771799.3151
ENSG00000108424homo_sapiensENSP0000029015899.200998.9726pteropus_vampyrusENSPVAP0000000464699.314399.0857
ENSG00000108424homo_sapiensENSP0000029015896.118794.4064myotis_lucifugusENSMLUP0000001321895.899894.1913
ENSG00000108424homo_sapiensENSP0000029015899.429298.4018vombatus_ursinusENSVURP0001000917999.429298.4018
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292rhinolophus_ferrumequinumENSRFEP0001001248599.657599.4292
ENSG00000108424homo_sapiensENSP0000029015895.890495.5479neovison_visonENSNVIP0000000681095.890495.5479
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292bos_taurusENSBTAP0000000865099.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.657599.2009heterocephalus_glaber_femaleENSHGLP0000001974899.657599.2009
ENSG00000108424homo_sapiensENSP0000029015810099.7717rhinopithecus_bietiENSRBIP0000000046199.88699.6579
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292canis_lupus_dingoENSCAFP0002002977699.543999.3158
ENSG00000108424homo_sapiensENSP0000029015899.771799.4292sciurus_vulgarisENSSVLP0000502200599.771799.4292
ENSG00000108424homo_sapiensENSP0000029015899.429298.4018phascolarctos_cinereusENSPCIP0000005302599.315898.2896
ENSG00000108424homo_sapiensENSP0000029015861.872161.758procavia_capensisENSPCAP0000000241164.294264.1756
ENSG00000108424homo_sapiensENSP0000029015896.689596.1187nannospalax_galiliENSNGAP0000001709596.689596.1187
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292bos_grunniensENSBGRP0000002974599.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.657598.9726chinchilla_lanigeraENSCLAP0000002489799.657598.9726
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292cervus_hanglu_yarkandensisENSCHYP0000000057899.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.543499.2009catagonus_wagneriENSCWAP0000000089799.543499.2009
ENSG00000108424homo_sapiensENSP0000029015899.771799.4292ictidomys_tridecemlineatusENSSTOP0000000708799.657999.3158
ENSG00000108424homo_sapiensENSP0000029015899.657599.5434otolemur_garnettiiENSOGAP0000000549699.657599.5434
ENSG00000108424homo_sapiensENSP0000029015893.721592.9224cebus_imitatorENSCCAP0000002305895.687694.8718
ENSG00000108424homo_sapiensENSP0000029015881.735279.3379cebus_imitatorENSCCAP0000000372996.626293.7922
ENSG00000108424homo_sapiensENSP0000029015899.771799.4292urocitellus_parryiiENSUPAP0001000824099.771799.4292
ENSG00000108424homo_sapiensENSP0000029015899.657599.4292moschus_moschiferusENSMMSP0000002465399.657599.4292
ENSG00000108424homo_sapiensENSP0000029015899.086898.7443rhinopithecus_roxellanaENSRROP0000001222899.770199.4253
ENSG00000108424homo_sapiensENSP0000029015899.771799.6575propithecus_coquereliENSPCOP0000002753199.771799.6575
ENSG00000108424homo_sapiensENSP0000029015867.009148.8584caenorhabditis_elegansF28B3.8.265.513447.7679
ENSG00000108424homo_sapiensENSP0000029015877.16961.6438drosophila_melanogasterFBpp029403776.470661.086
ENSG00000108424homo_sapiensENSP0000029015879.908764.3836ciona_intestinalisENSCINP0000000962579.275263.8732
ENSG00000108424homo_sapiensENSP0000029015893.607386.3014petromyzon_marinusENSPMAP0000000788693.287886.0068
ENSG00000108424homo_sapiensENSP0000029015889.954381.1644eptatretus_burgeriENSEBUP0000002255891.309482.387
ENSG00000108424homo_sapiensENSP0000029015890.639385.9589callorhinchus_miliiENSCMIP0000003731187.63883.1126
ENSG00000108424homo_sapiensENSP0000029015886.073183.2192latimeria_chalumnaeENSLACP0000002004797.039993.8224
ENSG00000108424homo_sapiensENSP0000029015897.374493.4931lepisosteus_oculatusENSLOCP0000001696897.152693.2802
ENSG00000108424homo_sapiensENSP0000029015894.292289.3836clupea_harengusENSCHAP0000002069789.200984.5572
ENSG00000108424homo_sapiensENSP0000029015897.260392.1233danio_rerioENSDARP0000013551997.260392.1233
ENSG00000108424homo_sapiensENSP0000029015894.520589.4977carassius_auratusENSCARP0000000656989.902385.1249
ENSG00000108424homo_sapiensENSP0000029015895.433890.6393carassius_auratusENSCARP0000011002689.411884.9198
ENSG00000108424homo_sapiensENSP0000029015897.488692.9224astyanax_mexicanusENSAMXP0000003428397.488692.9224
ENSG00000108424homo_sapiensENSP0000029015891.666787.3288ictalurus_punctatusENSIPUP0000001829692.832488.4393
ENSG00000108424homo_sapiensENSP0000029015897.488692.8082esox_luciusENSELUP0000006920197.488692.8082
ENSG00000108424homo_sapiensENSP0000029015894.178189.3836electrophorus_electricusENSEEEP0000003499290.163985.5738
ENSG00000108424homo_sapiensENSP0000029015896.917892.0091oncorhynchus_kisutchENSOKIP0000501731496.477391.5909
ENSG00000108424homo_sapiensENSP0000029015896.803692.3516oncorhynchus_kisutchENSOKIP0000502581795.388191.0011
ENSG00000108424homo_sapiensENSP0000029015897.488692.9224oncorhynchus_mykissENSOMYP0000002211697.045592.5
ENSG00000108424homo_sapiensENSP0000029015895.776390.7534oncorhynchus_mykissENSOMYP0000006974992.604987.7483
ENSG00000108424homo_sapiensENSP0000029015894.634789.9543salmo_salarENSSSAP0000012791785.552181.3209
ENSG00000108424homo_sapiensENSP0000029015895.091389.6119salmo_salarENSSSAP0000009428392.452887.1254
ENSG00000108424homo_sapiensENSP0000029015895.091390.2968salmo_truttaENSSTUP0000000351385.876381.5464
ENSG00000108424homo_sapiensENSP0000029015895.091389.4977salmo_truttaENSSTUP0000005227688.711483.4931
ENSG00000108424homo_sapiensENSP0000029015894.063989.4977gadus_morhuaENSGMOP0000006677186.828282.6133
ENSG00000108424homo_sapiensENSP0000029015897.260392.2374fundulus_heteroclitusENSFHEP0000001831497.260392.2374
ENSG00000108424homo_sapiensENSP0000029015897.146192.0091poecilia_reticulataENSPREP0000001814697.146192.0091
ENSG00000108424homo_sapiensENSP0000029015897.146192.1233xiphophorus_maculatusENSXMAP0000001888197.146192.1233
ENSG00000108424homo_sapiensENSP0000029015897.260392.8082oryzias_latipesENSORLP0000002475797.260392.8082
ENSG00000108424homo_sapiensENSP0000029015897.488692.9224cyclopterus_lumpusENSCLMP0000502951897.488692.9224
ENSG00000108424homo_sapiensENSP0000029015895.776390.6393oreochromis_niloticusENSONIP0000004667593.325988.3204
ENSG00000108424homo_sapiensENSP0000029015897.374492.8082haplochromis_burtoniENSHBUP0000001490097.374492.8082
ENSG00000108424homo_sapiensENSP0000029015896.461291.6667astatotilapia_callipteraENSACLP0000002231196.351291.5621
ENSG00000108424homo_sapiensENSP0000029015895.091390.0685sparus_aurataENSSAUP0001003340775.112771.1452
ENSG00000108424homo_sapiensENSP0000029015894.748989.8402lates_calcariferENSLCAP0001000739489.055884.4421
ENSG00000108424homo_sapiensENSP0000029015898.173595.0913xenopus_tropicalisENSXETP0000009377598.173595.0913
ENSG00000108424homo_sapiensENSP0000029015898.401896.8036chrysemys_picta_belliiENSCPBP0000003983194.310792.779
ENSG00000108424homo_sapiensENSP0000029015898.972697.4886sphenodon_punctatusENSSPUP0000002319298.972697.4886
ENSG00000108424homo_sapiensENSP0000029015896.803694.9772crocodylus_porosusENSCPRP0000500980787.603385.9504
ENSG00000108424homo_sapiensENSP0000029015898.858496.5753laticauda_laticaudataENSLLTP0000000775098.858496.5753
ENSG00000108424homo_sapiensENSP0000029015832.648431.7352notechis_scutatusENSNSUP0000000165198.281895.5326
ENSG00000108424homo_sapiensENSP0000029015893.37991.7808notechis_scutatusENSNSUP0000001070092.954591.3636
ENSG00000108424homo_sapiensENSP0000029015892.579989.2694pseudonaja_textilisENSPTXP0000001655495.749792.3259
ENSG00000108424homo_sapiensENSP0000029015898.744396.9178pseudonaja_textilisENSPTXP0000002011898.744396.9178
ENSG00000108424homo_sapiensENSP0000029015896.34794.863anas_platyrhynchos_platyrhynchosENSAPLP0000000997993.05491.6207
ENSG00000108424homo_sapiensENSP0000029015898.51696.5753gallus_gallusENSGALP0001003541197.514195.5932
ENSG00000108424homo_sapiensENSP0000029015856.735255.0228meleagris_gallopavoENSMGAP0000000246890.036287.3188
ENSG00000108424homo_sapiensENSP0000029015832.990932.3059meleagris_gallopavoENSMGAP0000001756799.312797.2509
ENSG00000108424homo_sapiensENSP0000029015892.694190.5251serinus_canariaENSSCAP0000001332694.528592.3167
ENSG00000108424homo_sapiensENSP0000029015893.835691.895parus_majorENSPMJP0000002411497.740895.7194
ENSG00000108424homo_sapiensENSP0000029015898.744397.1461anolis_carolinensisENSACAP0000000707298.744397.1461
ENSG00000108424homo_sapiensENSP0000029015897.374492.8082neolamprologus_brichardiENSNBRP0000002525897.374492.8082
ENSG00000108424homo_sapiensENSP0000029015873.744371.0046naja_najaENSNNAP0000001648588.372185.0889
ENSG00000108424homo_sapiensENSP0000029015898.744396.4612naja_najaENSNNAP0000001187898.744396.4612
ENSG00000108424homo_sapiensENSP0000029015898.744397.1461podarcis_muralisENSPMRP0000002061398.744397.1461
ENSG00000108424homo_sapiensENSP0000029015896.004694.0639geospiza_fortisENSGFOP0000000934898.247796.2617
ENSG00000108424homo_sapiensENSP0000029015899.200997.2603taeniopygia_guttataENSTGUP0000000352099.200997.2603
ENSG00000108424homo_sapiensENSP0000029015896.803692.9224erpetoichthys_calabaricusENSECRP0000003250196.803692.9224
ENSG00000108424homo_sapiensENSP0000029015896.917891.895kryptolebias_marmoratusENSKMAP0000000199996.917891.895
ENSG00000108424homo_sapiensENSP0000029015898.630196.6895salvator_merianaeENSSMRP0000000024198.630196.6895
ENSG00000108424homo_sapiensENSP0000029015897.374492.9224oryzias_javanicusENSOJAP0000000262397.374492.9224
ENSG00000108424homo_sapiensENSP0000029015895.433890.6393amphilophus_citrinellusENSACIP0000002989597.549692.6488
ENSG00000108424homo_sapiensENSP0000029015895.091390.411dicentrarchus_labraxENSDLAP0000500722889.281984.8875
ENSG00000108424homo_sapiensENSP0000029015897.374492.9224amphiprion_perculaENSAPEP0000001167797.374492.9224
ENSG00000108424homo_sapiensENSP0000029015820.205518.6073oryzias_sinensisENSOSIP0000002038793.650886.2434
ENSG00000108424homo_sapiensENSP0000029015895.776394.6347pelodiscus_sinensisENSPSIP0000001095599.525598.3393
ENSG00000108424homo_sapiensENSP0000029015899.429298.1735gopherus_evgoodeiENSGEVP0000502407599.429298.1735
ENSG00000108424homo_sapiensENSP0000029015897.602796.2329chelonoidis_abingdoniiENSCABP0000000347389.341788.0878
ENSG00000108424homo_sapiensENSP0000029015897.716993.1507seriola_dumeriliENSSDUP0000002228297.716993.1507
ENSG00000108424homo_sapiensENSP0000029015896.689595.2055struthio_camelus_australisENSSCUP0000002477997.693296.1938
ENSG00000108424homo_sapiensENSP0000029015897.260395.0913anser_brachyrhynchusENSABRP0000000639597.371495.2
ENSG00000108424homo_sapiensENSP0000029015893.949889.4977gasterosteus_aculeatusENSGACP0000001950992.161387.794
ENSG00000108424homo_sapiensENSP0000029015893.264887.6712cynoglossus_semilaevisENSCSEP0000001241295.89290.1408
ENSG00000108424homo_sapiensENSP0000029015897.146192.0091poecilia_formosaENSPFOP0000000909397.146192.0091
ENSG00000108424homo_sapiensENSP0000029015889.840284.589myripristis_murdjanENSMMDP0000500415887.639282.5167
ENSG00000108424homo_sapiensENSP0000029015893.949889.4977sander_luciopercaENSSLUP0000001939885.196781.1594
ENSG00000108424homo_sapiensENSP0000029015899.086897.2603strigops_habroptilaENSSHBP0000501095699.086897.2603
ENSG00000108424homo_sapiensENSP0000029015897.374492.9224amphiprion_ocellarisENSAOCP0000002191497.374492.9224
ENSG00000108424homo_sapiensENSP0000029015899.429298.1735terrapene_carolina_triunguisENSTMTP0000000949799.429298.1735
ENSG00000108424homo_sapiensENSP0000029015896.917892.1233hucho_huchoENSHHUP0000000922196.58791.8089
ENSG00000108424homo_sapiensENSP0000029015897.374492.8082hucho_huchoENSHHUP0000004458897.263492.7024
ENSG00000108424homo_sapiensENSP0000029015897.374492.6941betta_splendensENSBSLP0000000531492.717488.2609
ENSG00000108424homo_sapiensENSP0000029015889.954384.7032pygocentrus_nattereriENSPNAP0000003461391.627986.2791
ENSG00000108424homo_sapiensENSP0000029015897.03292.3516anabas_testudineusENSATEP0000002189397.03292.3516
ENSG00000108424homo_sapiensENSP0000029015879.337962.7854ciona_savignyiENSCSAVP0000001474676.710860.7064
ENSG00000108424homo_sapiensENSP0000029015853.538833.6758saccharomyces_cerevisiaeYLR347C54.471534.2625
ENSG00000108424homo_sapiensENSP0000029015895.776391.21seriola_lalandi_dorsalisENSSLDP0000002781994.909590.3846
ENSG00000108424homo_sapiensENSP0000029015896.461291.6667labrus_bergyltaENSLBEP0000003431794.730990.0224
ENSG00000108424homo_sapiensENSP0000029015827.625626.3699labrus_bergyltaENSLBEP0000000905396.414392.0319
ENSG00000108424homo_sapiensENSP0000029015897.374492.6941pundamilia_nyerereiENSPNYP0000002349193.122388.6463
ENSG00000108424homo_sapiensENSP0000029015894.748989.9543mastacembelus_armatusENSMAMP0000003631089.729785.1892
ENSG00000108424homo_sapiensENSP0000029015897.374492.9224stegastes_partitusENSSPAP0000002566497.374492.9224
ENSG00000108424homo_sapiensENSP0000029015889.497784.1324oncorhynchus_tshawytschaENSOTSP0000503810690.635885.2023
ENSG00000108424homo_sapiensENSP0000029015893.607388.4703oncorhynchus_tshawytschaENSOTSP0000506751596.357291.0693
ENSG00000108424homo_sapiensENSP0000029015897.374492.9224acanthochromis_polyacanthusENSAPOP0000001730397.374492.9224
ENSG00000108424homo_sapiensENSP0000029015899.315197.831aquila_chrysaetos_chrysaetosENSACCP0002000789499.315197.831
ENSG00000108424homo_sapiensENSP0000029015832.077630.8219nothobranchius_furzeriENSNFUP0001503103096.563692.7835
ENSG00000108424homo_sapiensENSP0000029015818.37917.2374nothobranchius_furzeriENSNFUP0001503295988.461582.967
ENSG00000108424homo_sapiensENSP0000029015832.191830.8219cyprinodon_variegatusENSCVAP0000002669096.907292.7835
ENSG00000108424homo_sapiensENSP0000029015818.607317.5799cyprinodon_variegatusENSCVAP0000001033791.061586.0335
ENSG00000108424homo_sapiensENSP0000029015893.835689.1553denticeps_clupeoidesENSDCDP0000002495289.640185.169
ENSG00000108424homo_sapiensENSP0000029015889.72684.3607larimichthys_croceaENSLCRP0000506020688.713383.4086
ENSG00000108424homo_sapiensENSP0000029015896.004690.2968takifugu_rubripesENSTRUP0000000128396.004690.2968
ENSG00000108424homo_sapiensENSP0000029015852.853951.484ficedula_albicollisENSFALP0000003383496.257893.763
ENSG00000108424homo_sapiensENSP0000029015890.753484.3607hippocampus_comesENSHCOP0000000114089.52783.2207
ENSG00000108424homo_sapiensENSP0000029015897.03292.4658cyprinus_carpio_carpioENSCCRP0000009271588.63484.463
ENSG00000108424homo_sapiensENSP0000029015894.520589.6119cyprinus_carpio_carpioENSCCRP0000009105990.789586.0746
ENSG00000108424homo_sapiensENSP0000029015899.429297.6027coturnix_japonicaENSCJPP0000500082499.429297.6027
ENSG00000108424homo_sapiensENSP0000029015897.146192.0091poecilia_latipinnaENSPLAP0000002458297.146192.0091
ENSG00000108424homo_sapiensENSP0000029015894.634789.3836sinocyclocheilus_grahamiENSSGRP0000005765983.991979.3313
ENSG00000108424homo_sapiensENSP0000029015894.748989.6119sinocyclocheilus_grahamiENSSGRP0000003759287.737882.981
ENSG00000108424homo_sapiensENSP0000029015896.34791.6667maylandia_zebraENSMZEP0000500596996.237291.5621
ENSG00000108424homo_sapiensENSP0000029015896.461290.5251tetraodon_nigroviridisENSTNIP0000000926396.461290.5251
ENSG00000108424homo_sapiensENSP0000029015820.205518.9498tetraodon_nigroviridisENSTNIP0000002285598.333392.2222
ENSG00000108424homo_sapiensENSP0000029015897.83193.0365paramormyrops_kingsleyaeENSPKIP0000004074297.719592.9304
ENSG00000108424homo_sapiensENSP0000029015897.716993.6073scleropages_formosusENSSFOP0001506608397.716993.6073
ENSG00000108424homo_sapiensENSP0000029015893.949889.0411leptobrachium_leishanenseENSLLEP0000003868295.36590.3824
ENSG00000108424homo_sapiensENSP0000029015895.776391.21scophthalmus_maximusENSSMAP0000006923582.497578.5644
ENSG00000108424homo_sapiensENSP0000029015897.260392.8082oryzias_melastigmaENSOMEP0000001919694.983390.6355

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005635located_in nuclear envelope1IDAHomo_sapiens(9606)Component
GO:0005643part_of nuclear pore1TASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm3IDA,NAS,TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm3IBA,IDA,ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol3IDA,NAS,TASHomo_sapiens(9606)Component
GO:0006404involved_in RNA import into nucleus1IDAHomo_sapiens(9606)Process
GO:0006606involved_in protein import into nucleus5IBA,IDA,IMP,ISSHomo_sapiens(9606)Process
GO:0006607involved_in NLS-bearing protein import into nucleus2IDA,ISSHomo_sapiens(9606)Process
GO:0006610involved_in ribosomal protein import into nucleus1IDAHomo_sapiens(9606)Process
GO:0007079involved_in mitotic chromosome movement towards spindle pole1IMPHomo_sapiens(9606)Process
GO:0007080involved_in mitotic metaphase plate congression1IMPHomo_sapiens(9606)Process
GO:0008139enables nuclear localization sequence binding1IBAHomo_sapiens(9606)Function
GO:0008270enables zinc ion binding1TASHomo_sapiens(9606)Function
GO:0010494located_in cytoplasmic stress granule1ISSHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0019904enables protein domain specific binding1IPIHomo_sapiens(9606)Function
GO:0030953involved_in astral microtubule organization1IMPHomo_sapiens(9606)Process
GO:0031267enables small GTPase binding1IEAHomo_sapiens(9606)Function
GO:0031291involved_in Ran protein signal transduction1IMPHomo_sapiens(9606)Process
GO:0031965located_in nuclear membrane1IDAHomo_sapiens(9606)Component
GO:0035580located_in specific granule lumen1TASHomo_sapiens(9606)Component
GO:0040001involved_in establishment of mitotic spindle localization1IMPHomo_sapiens(9606)Process
GO:0042564part_of NLS-dependent protein nuclear import complex2IPI,ISSHomo_sapiens(9606)Component
GO:0045184involved_in establishment of protein localization1IMPHomo_sapiens(9606)Process
GO:0051879enables Hsp90 protein binding1IEAHomo_sapiens(9606)Function
GO:0061608enables nuclear import signal receptor activity3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0061676enables importin-alpha family protein binding1IEAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0071782located_in endoplasmic reticulum tubular network1IDAHomo_sapiens(9606)Component
GO:0090307involved_in mitotic spindle assembly1IMPHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component

Expression