RBP Type
Canonical_RBPs
Diseases
CancerCHIKV Flaviviruses HIV IAV SARS-COV-2 SINV Dengue
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
Metabolic enzyme
Localizations
Stress granucle
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000108424 Gene ID
3837
Accession
6400
Symbol
KPNB1
Alias
IMB1;IPO1;IPOB;Impnb;NTF97
Full Name
karyopherin subunit beta 1
Status
Confidence
Length
36030 bases
Strand
Plus strand
Position
17 : 47649476 - 47685505
RNA binding domain
IBN_N
Summary
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000290158
IBN_N
PF03810
2.9e-11
1
ENSP00000464042
IBN_N
PF03810
2.9e-11
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
32413045
Mutation severity spectrum of rare alleles in the human genome is predictive of disease type.
Jimin Pei
2020-05-01
PLoS computational biology
26791949
Host gene expression classifiers diagnose acute respiratory illness etiology.
L Ephraim Tsalik
2016-01-20
Science translational medicine
Name
Transcript ID
bp
Protein
Translation ID
KPNB1-202
ENST00000535458
3163
731aa
ENSP00000438253
KPNB1-214
ENST00000583648
6182
876aa
ENSP00000464042
KPNB1-201
ENST00000290158
6058
876aa
ENSP00000290158
KPNB1-205
ENST00000577918
859
No protein
-
KPNB1-204
ENST00000577875
605
60aa
ENSP00000464200
KPNB1-203
ENST00000540627
2989
731aa
ENSP00000438964
KPNB1-211
ENST00000582097
2347
690aa
ENSP00000463066
KPNB1-215
ENST00000677036
1216
No protein
-
KPNB1-213
ENST00000583013
742
248aa
ENSP00000463190
KPNB1-216
ENST00000677341
2197
No protein
-
KPNB1-207
ENST00000579901
594
No protein
-
KPNB1-206
ENST00000578718
550
No protein
-
KPNB1-208
ENST00000580019
427
No protein
-
KPNB1-210
ENST00000580573
2087
No protein
-
KPNB1-209
ENST00000580158
3338
No protein
-
KPNB1-212
ENST00000582126
653
22aa
ENSP00000462243
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
85542 Optic Disk 2E-8 25631615 90317 Optic Disk 2E-8 25631615 94643 Multiple Sclerosis 1E-7 22190364 103995 Spondylitis, Ankylosing 5E-8 21743469
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000108424 homo_sapiens ENSP00000346453 30.3423 16.3737 homo_sapiens ENSP00000290158 37.4429 20.2055 ENSG00000108424 homo_sapiens ENSP00000407182 27.3133 12.5975 homo_sapiens ENSP00000290158 27.968 12.8995 ENSG00000108424 homo_sapiens ENSP00000499125 29.1705 14.1294 homo_sapiens ENSP00000290158 36.5297 17.6941 ENSG00000108424 homo_sapiens ENSP00000336712 27.6169 13.6971 homo_sapiens ENSP00000290158 28.3105 14.0411 ENSG00000108424 homo_sapiens ENSP00000259569 28.2353 13.3032 homo_sapiens ENSP00000290158 35.6164 16.7808
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000108424 homo_sapiens ENSP00000290158 100 100 nomascus_leucogenys ENSNLEP00000001948 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 pan_paniscus ENSPPAP00000011352 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 pongo_abelii ENSPPYP00000023559 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 pan_troglodytes ENSPTRP00000015867 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 gorilla_gorilla ENSGGOP00000007915 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 98.7443 97.9452 ornithorhynchus_anatinus ENSOANP00000008546 98.7443 97.9452 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 98.516 sarcophilus_harrisii ENSSHAP00000021501 99.5434 98.516 ENSG00000108424 homo_sapiens ENSP00000290158 93.8356 92.8082 notamacropus_eugenii ENSMEUP00000013051 93.9429 92.9143 ENSG00000108424 homo_sapiens ENSP00000290158 63.3562 63.0137 choloepus_hoffmanni ENSCHOP00000009390 64.7608 64.4107 ENSG00000108424 homo_sapiens ENSP00000290158 79.1096 78.653 dasypus_novemcinctus ENSDNOP00000011284 99.569 98.9943 ENSG00000108424 homo_sapiens ENSP00000290158 80.137 79.4521 erinaceus_europaeus ENSEEUP00000004636 83.274 82.5623 ENSG00000108424 homo_sapiens ENSP00000290158 54.2237 53.653 echinops_telfairi ENSETEP00000003588 60.7417 60.1023 ENSG00000108424 homo_sapiens ENSP00000290158 100 99.8858 callithrix_jacchus ENSCJAP00000014713 100 99.8858 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 cercocebus_atys ENSCATP00000027564 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.7717 macaca_fascicularis ENSMFAP00000014277 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 97.7169 97.7169 macaca_mulatta ENSMMUP00000025988 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 macaca_nemestrina ENSMNEP00000035729 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 papio_anubis ENSPANP00000020466 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 96.9178 mandrillus_leucophaeus ENSMLEP00000028255 97.5973 97.1396 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 95.5479 tursiops_truncatus ENSTTRP00000004423 99.5255 99.2883 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 vulpes_vulpes ENSVVUP00000003934 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.2009 mus_spretus MGP_SPRETEiJ_P0030932 99.4312 98.8623 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 equus_asinus ENSEASP00005000942 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 capra_hircus ENSCHIP00000013556 99.5439 99.3158 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 94.0639 loxodonta_africana ENSLAFP00000001118 96.1054 94.3872 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 panthera_leo ENSPLOP00000007974 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 95.8904 95.6621 ailuropoda_melanoleuca ENSAMEP00000004904 97.4478 97.2158 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 bos_indicus_hybrid ENSBIXP00005027750 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.8858 99.4292 oryctolagus_cuniculus ENSOCUP00000013258 99.8858 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 equus_caballus ENSECAP00000060703 95.9341 95.7143 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 canis_lupus_familiaris ENSCAFP00845021394 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 96.2329 panthera_pardus ENSPPRP00000003251 97.7038 96.7853 ENSG00000108424 homo_sapiens ENSP00000290158 96.0046 95.6621 marmota_marmota_marmota ENSMMMP00000023188 99.7627 99.4069 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.3151 balaenoptera_musculus ENSBMSP00010029652 99.5434 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.0868 cavia_porcellus ENSCPOP00000026151 99.6575 99.0868 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 felis_catus ENSFCAP00000019089 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 ursus_americanus ENSUAMP00000033250 99.5439 99.3158 ENSG00000108424 homo_sapiens ENSP00000290158 99.4292 98.4018 monodelphis_domestica ENSMODP00000052995 99.3158 98.2896 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 97.1461 bison_bison_bison ENSBBBP00000014365 97.3744 97.1461 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.3151 monodon_monoceros ENSMMNP00015023451 99.5434 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.2009 sus_scrofa ENSSSCP00000018562 99.5434 99.2009 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.6575 microcebus_murinus ENSMICP00000010981 83.8772 83.7812 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 98.7443 octodon_degus ENSODEP00000023604 99.6575 98.7443 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.0868 jaculus_jaculus ENSJJAP00000006189 99.7717 99.0868 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 ovis_aries_rambouillet ENSOARP00020025784 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 96.2329 ursus_maritimus ENSUMAP00000022926 95.5107 94.6128 ENSG00000108424 homo_sapiens ENSP00000290158 90.8676 90.5251 ochotona_princeps ENSOPRP00000003512 92.7739 92.4242 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.3151 delphinapterus_leucas ENSDLEP00000005657 99.4299 99.2018 ENSG00000108424 homo_sapiens ENSP00000290158 75.4566 75.2283 physeter_catodon ENSPCTP00005007374 99.5482 99.247 ENSG00000108424 homo_sapiens ENSP00000290158 93.6073 93.0365 mus_caroli MGP_CAROLIEiJ_P0029512 99.7567 99.1484 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.2009 mus_musculus ENSMUSP00000001479 99.7717 99.2009 ENSG00000108424 homo_sapiens ENSP00000290158 99.0868 98.516 mustela_putorius_furo ENSMPUP00000015111 98.9738 98.4036 ENSG00000108424 homo_sapiens ENSP00000290158 94.0639 92.3516 aotus_nancymaae ENSANAP00000035246 96.7136 94.953 ENSG00000108424 homo_sapiens ENSP00000290158 97.4886 97.2603 aotus_nancymaae ENSANAP00000014067 98.9571 98.7254 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 saimiri_boliviensis_boliviensis ENSSBOP00000027379 94.2949 94.2949 ENSG00000108424 homo_sapiens ENSP00000290158 85.274 84.589 vicugna_pacos ENSVPAP00000003411 86.6589 85.9629 ENSG00000108424 homo_sapiens ENSP00000290158 100 100 chlorocebus_sabaeus ENSCSAP00000015441 100 100 ENSG00000108424 homo_sapiens ENSP00000290158 79.2237 79.1096 tupaia_belangeri ENSTBEP00000009145 95.1989 95.0617 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.3151 mesocricetus_auratus ENSMAUP00000004678 99.7717 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.3151 phocoena_sinus ENSPSNP00000026018 99.5434 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.0868 camelus_dromedarius ENSCDRP00005027692 99.5434 99.0868 ENSG00000108424 homo_sapiens ENSP00000290158 97.7169 97.3744 carlito_syrichta ENSTSYP00000013293 98.9595 98.6127 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 96.2329 panthera_tigris_altaica ENSPTIP00000004377 97.7038 96.7853 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.2009 rattus_norvegicus ENSRNOP00000012376 99.7717 99.2009 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.6575 prolemur_simus ENSPSMP00000010874 99.6579 99.5439 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.3151 microtus_ochrogaster ENSMOCP00000004447 99.7717 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 76.484 76.0274 sorex_araneus ENSSARP00000001365 76.5714 76.1143 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.3151 peromyscus_maniculatus_bairdii ENSPEMP00000019514 99.7717 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 95.8904 95.6621 bos_mutus ENSBMUP00000001175 95.8904 95.6621 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.2009 mus_spicilegus ENSMSIP00000021192 99.7717 99.2009 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.3151 cricetulus_griseus_chok1gshd ENSCGRP00001015433 99.7717 99.3151 ENSG00000108424 homo_sapiens ENSP00000290158 99.2009 98.9726 pteropus_vampyrus ENSPVAP00000004646 99.3143 99.0857 ENSG00000108424 homo_sapiens ENSP00000290158 96.1187 94.4064 myotis_lucifugus ENSMLUP00000013218 95.8998 94.1913 ENSG00000108424 homo_sapiens ENSP00000290158 99.4292 98.4018 vombatus_ursinus ENSVURP00010009179 99.4292 98.4018 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 rhinolophus_ferrumequinum ENSRFEP00010012485 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 95.8904 95.5479 neovison_vison ENSNVIP00000006810 95.8904 95.5479 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 bos_taurus ENSBTAP00000008650 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.2009 heterocephalus_glaber_female ENSHGLP00000019748 99.6575 99.2009 ENSG00000108424 homo_sapiens ENSP00000290158 100 99.7717 rhinopithecus_bieti ENSRBIP00000000461 99.886 99.6579 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 canis_lupus_dingo ENSCAFP00020029776 99.5439 99.3158 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.4292 sciurus_vulgaris ENSSVLP00005022005 99.7717 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.4292 98.4018 phascolarctos_cinereus ENSPCIP00000053025 99.3158 98.2896 ENSG00000108424 homo_sapiens ENSP00000290158 61.8721 61.758 procavia_capensis ENSPCAP00000002411 64.2942 64.1756 ENSG00000108424 homo_sapiens ENSP00000290158 96.6895 96.1187 nannospalax_galili ENSNGAP00000017095 96.6895 96.1187 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 bos_grunniens ENSBGRP00000029745 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 98.9726 chinchilla_lanigera ENSCLAP00000024897 99.6575 98.9726 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 cervus_hanglu_yarkandensis ENSCHYP00000000578 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.5434 99.2009 catagonus_wagneri ENSCWAP00000000897 99.5434 99.2009 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.4292 ictidomys_tridecemlineatus ENSSTOP00000007087 99.6579 99.3158 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.5434 otolemur_garnettii ENSOGAP00000005496 99.6575 99.5434 ENSG00000108424 homo_sapiens ENSP00000290158 93.7215 92.9224 cebus_imitator ENSCCAP00000023058 95.6876 94.8718 ENSG00000108424 homo_sapiens ENSP00000290158 81.7352 79.3379 cebus_imitator ENSCCAP00000003729 96.6262 93.7922 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.4292 urocitellus_parryii ENSUPAP00010008240 99.7717 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.6575 99.4292 moschus_moschiferus ENSMMSP00000024653 99.6575 99.4292 ENSG00000108424 homo_sapiens ENSP00000290158 99.0868 98.7443 rhinopithecus_roxellana ENSRROP00000012228 99.7701 99.4253 ENSG00000108424 homo_sapiens ENSP00000290158 99.7717 99.6575 propithecus_coquereli ENSPCOP00000027531 99.7717 99.6575 ENSG00000108424 homo_sapiens ENSP00000290158 67.0091 48.8584 caenorhabditis_elegans F28B3.8.2 65.5134 47.7679 ENSG00000108424 homo_sapiens ENSP00000290158 77.169 61.6438 drosophila_melanogaster FBpp0294037 76.4706 61.086 ENSG00000108424 homo_sapiens ENSP00000290158 79.9087 64.3836 ciona_intestinalis ENSCINP00000009625 79.2752 63.8732 ENSG00000108424 homo_sapiens ENSP00000290158 93.6073 86.3014 petromyzon_marinus ENSPMAP00000007886 93.2878 86.0068 ENSG00000108424 homo_sapiens ENSP00000290158 89.9543 81.1644 eptatretus_burgeri ENSEBUP00000022558 91.3094 82.387 ENSG00000108424 homo_sapiens ENSP00000290158 90.6393 85.9589 callorhinchus_milii ENSCMIP00000037311 87.638 83.1126 ENSG00000108424 homo_sapiens ENSP00000290158 86.0731 83.2192 latimeria_chalumnae ENSLACP00000020047 97.0399 93.8224 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 93.4931 lepisosteus_oculatus ENSLOCP00000016968 97.1526 93.2802 ENSG00000108424 homo_sapiens ENSP00000290158 94.2922 89.3836 clupea_harengus ENSCHAP00000020697 89.2009 84.5572 ENSG00000108424 homo_sapiens ENSP00000290158 97.2603 92.1233 danio_rerio ENSDARP00000135519 97.2603 92.1233 ENSG00000108424 homo_sapiens ENSP00000290158 94.5205 89.4977 carassius_auratus ENSCARP00000006569 89.9023 85.1249 ENSG00000108424 homo_sapiens ENSP00000290158 95.4338 90.6393 carassius_auratus ENSCARP00000110026 89.4118 84.9198 ENSG00000108424 homo_sapiens ENSP00000290158 97.4886 92.9224 astyanax_mexicanus ENSAMXP00000034283 97.4886 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 91.6667 87.3288 ictalurus_punctatus ENSIPUP00000018296 92.8324 88.4393 ENSG00000108424 homo_sapiens ENSP00000290158 97.4886 92.8082 esox_lucius ENSELUP00000069201 97.4886 92.8082 ENSG00000108424 homo_sapiens ENSP00000290158 94.1781 89.3836 electrophorus_electricus ENSEEEP00000034992 90.1639 85.5738 ENSG00000108424 homo_sapiens ENSP00000290158 96.9178 92.0091 oncorhynchus_kisutch ENSOKIP00005017314 96.4773 91.5909 ENSG00000108424 homo_sapiens ENSP00000290158 96.8036 92.3516 oncorhynchus_kisutch ENSOKIP00005025817 95.3881 91.0011 ENSG00000108424 homo_sapiens ENSP00000290158 97.4886 92.9224 oncorhynchus_mykiss ENSOMYP00000022116 97.0455 92.5 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 90.7534 oncorhynchus_mykiss ENSOMYP00000069749 92.6049 87.7483 ENSG00000108424 homo_sapiens ENSP00000290158 94.6347 89.9543 salmo_salar ENSSSAP00000127917 85.5521 81.3209 ENSG00000108424 homo_sapiens ENSP00000290158 95.0913 89.6119 salmo_salar ENSSSAP00000094283 92.4528 87.1254 ENSG00000108424 homo_sapiens ENSP00000290158 95.0913 90.2968 salmo_trutta ENSSTUP00000003513 85.8763 81.5464 ENSG00000108424 homo_sapiens ENSP00000290158 95.0913 89.4977 salmo_trutta ENSSTUP00000052276 88.7114 83.4931 ENSG00000108424 homo_sapiens ENSP00000290158 94.0639 89.4977 gadus_morhua ENSGMOP00000066771 86.8282 82.6133 ENSG00000108424 homo_sapiens ENSP00000290158 97.2603 92.2374 fundulus_heteroclitus ENSFHEP00000018314 97.2603 92.2374 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 92.0091 poecilia_reticulata ENSPREP00000018146 97.1461 92.0091 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 92.1233 xiphophorus_maculatus ENSXMAP00000018881 97.1461 92.1233 ENSG00000108424 homo_sapiens ENSP00000290158 97.2603 92.8082 oryzias_latipes ENSORLP00000024757 97.2603 92.8082 ENSG00000108424 homo_sapiens ENSP00000290158 97.4886 92.9224 cyclopterus_lumpus ENSCLMP00005029518 97.4886 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 90.6393 oreochromis_niloticus ENSONIP00000046675 93.3259 88.3204 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.8082 haplochromis_burtoni ENSHBUP00000014900 97.3744 92.8082 ENSG00000108424 homo_sapiens ENSP00000290158 96.4612 91.6667 astatotilapia_calliptera ENSACLP00000022311 96.3512 91.5621 ENSG00000108424 homo_sapiens ENSP00000290158 95.0913 90.0685 sparus_aurata ENSSAUP00010033407 75.1127 71.1452 ENSG00000108424 homo_sapiens ENSP00000290158 94.7489 89.8402 lates_calcarifer ENSLCAP00010007394 89.0558 84.4421 ENSG00000108424 homo_sapiens ENSP00000290158 98.1735 95.0913 xenopus_tropicalis ENSXETP00000093775 98.1735 95.0913 ENSG00000108424 homo_sapiens ENSP00000290158 98.4018 96.8036 chrysemys_picta_bellii ENSCPBP00000039831 94.3107 92.779 ENSG00000108424 homo_sapiens ENSP00000290158 98.9726 97.4886 sphenodon_punctatus ENSSPUP00000023192 98.9726 97.4886 ENSG00000108424 homo_sapiens ENSP00000290158 96.8036 94.9772 crocodylus_porosus ENSCPRP00005009807 87.6033 85.9504 ENSG00000108424 homo_sapiens ENSP00000290158 98.8584 96.5753 laticauda_laticaudata ENSLLTP00000007750 98.8584 96.5753 ENSG00000108424 homo_sapiens ENSP00000290158 32.6484 31.7352 notechis_scutatus ENSNSUP00000001651 98.2818 95.5326 ENSG00000108424 homo_sapiens ENSP00000290158 93.379 91.7808 notechis_scutatus ENSNSUP00000010700 92.9545 91.3636 ENSG00000108424 homo_sapiens ENSP00000290158 92.5799 89.2694 pseudonaja_textilis ENSPTXP00000016554 95.7497 92.3259 ENSG00000108424 homo_sapiens ENSP00000290158 98.7443 96.9178 pseudonaja_textilis ENSPTXP00000020118 98.7443 96.9178 ENSG00000108424 homo_sapiens ENSP00000290158 96.347 94.863 anas_platyrhynchos_platyrhynchos ENSAPLP00000009979 93.054 91.6207 ENSG00000108424 homo_sapiens ENSP00000290158 98.516 96.5753 gallus_gallus ENSGALP00010035411 97.5141 95.5932 ENSG00000108424 homo_sapiens ENSP00000290158 56.7352 55.0228 meleagris_gallopavo ENSMGAP00000002468 90.0362 87.3188 ENSG00000108424 homo_sapiens ENSP00000290158 32.9909 32.3059 meleagris_gallopavo ENSMGAP00000017567 99.3127 97.2509 ENSG00000108424 homo_sapiens ENSP00000290158 92.6941 90.5251 serinus_canaria ENSSCAP00000013326 94.5285 92.3167 ENSG00000108424 homo_sapiens ENSP00000290158 93.8356 91.895 parus_major ENSPMJP00000024114 97.7408 95.7194 ENSG00000108424 homo_sapiens ENSP00000290158 98.7443 97.1461 anolis_carolinensis ENSACAP00000007072 98.7443 97.1461 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.8082 neolamprologus_brichardi ENSNBRP00000025258 97.3744 92.8082 ENSG00000108424 homo_sapiens ENSP00000290158 73.7443 71.0046 naja_naja ENSNNAP00000016485 88.3721 85.0889 ENSG00000108424 homo_sapiens ENSP00000290158 98.7443 96.4612 naja_naja ENSNNAP00000011878 98.7443 96.4612 ENSG00000108424 homo_sapiens ENSP00000290158 98.7443 97.1461 podarcis_muralis ENSPMRP00000020613 98.7443 97.1461 ENSG00000108424 homo_sapiens ENSP00000290158 96.0046 94.0639 geospiza_fortis ENSGFOP00000009348 98.2477 96.2617 ENSG00000108424 homo_sapiens ENSP00000290158 99.2009 97.2603 taeniopygia_guttata ENSTGUP00000003520 99.2009 97.2603 ENSG00000108424 homo_sapiens ENSP00000290158 96.8036 92.9224 erpetoichthys_calabaricus ENSECRP00000032501 96.8036 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 96.9178 91.895 kryptolebias_marmoratus ENSKMAP00000001999 96.9178 91.895 ENSG00000108424 homo_sapiens ENSP00000290158 98.6301 96.6895 salvator_merianae ENSSMRP00000000241 98.6301 96.6895 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.9224 oryzias_javanicus ENSOJAP00000002623 97.3744 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 95.4338 90.6393 amphilophus_citrinellus ENSACIP00000029895 97.5496 92.6488 ENSG00000108424 homo_sapiens ENSP00000290158 95.0913 90.411 dicentrarchus_labrax ENSDLAP00005007228 89.2819 84.8875 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.9224 amphiprion_percula ENSAPEP00000011677 97.3744 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 20.2055 18.6073 oryzias_sinensis ENSOSIP00000020387 93.6508 86.2434 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 94.6347 pelodiscus_sinensis ENSPSIP00000010955 99.5255 98.3393 ENSG00000108424 homo_sapiens ENSP00000290158 99.4292 98.1735 gopherus_evgoodei ENSGEVP00005024075 99.4292 98.1735 ENSG00000108424 homo_sapiens ENSP00000290158 97.6027 96.2329 chelonoidis_abingdonii ENSCABP00000003473 89.3417 88.0878 ENSG00000108424 homo_sapiens ENSP00000290158 97.7169 93.1507 seriola_dumerili ENSSDUP00000022282 97.7169 93.1507 ENSG00000108424 homo_sapiens ENSP00000290158 96.6895 95.2055 struthio_camelus_australis ENSSCUP00000024779 97.6932 96.1938 ENSG00000108424 homo_sapiens ENSP00000290158 97.2603 95.0913 anser_brachyrhynchus ENSABRP00000006395 97.3714 95.2 ENSG00000108424 homo_sapiens ENSP00000290158 93.9498 89.4977 gasterosteus_aculeatus ENSGACP00000019509 92.1613 87.794 ENSG00000108424 homo_sapiens ENSP00000290158 93.2648 87.6712 cynoglossus_semilaevis ENSCSEP00000012412 95.892 90.1408 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 92.0091 poecilia_formosa ENSPFOP00000009093 97.1461 92.0091 ENSG00000108424 homo_sapiens ENSP00000290158 89.8402 84.589 myripristis_murdjan ENSMMDP00005004158 87.6392 82.5167 ENSG00000108424 homo_sapiens ENSP00000290158 93.9498 89.4977 sander_lucioperca ENSSLUP00000019398 85.1967 81.1594 ENSG00000108424 homo_sapiens ENSP00000290158 99.0868 97.2603 strigops_habroptila ENSSHBP00005010956 99.0868 97.2603 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.9224 amphiprion_ocellaris ENSAOCP00000021914 97.3744 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 99.4292 98.1735 terrapene_carolina_triunguis ENSTMTP00000009497 99.4292 98.1735 ENSG00000108424 homo_sapiens ENSP00000290158 96.9178 92.1233 hucho_hucho ENSHHUP00000009221 96.587 91.8089 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.8082 hucho_hucho ENSHHUP00000044588 97.2634 92.7024 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.6941 betta_splendens ENSBSLP00000005314 92.7174 88.2609 ENSG00000108424 homo_sapiens ENSP00000290158 89.9543 84.7032 pygocentrus_nattereri ENSPNAP00000034613 91.6279 86.2791 ENSG00000108424 homo_sapiens ENSP00000290158 97.032 92.3516 anabas_testudineus ENSATEP00000021893 97.032 92.3516 ENSG00000108424 homo_sapiens ENSP00000290158 79.3379 62.7854 ciona_savignyi ENSCSAVP00000014746 76.7108 60.7064 ENSG00000108424 homo_sapiens ENSP00000290158 53.5388 33.6758 saccharomyces_cerevisiae YLR347C 54.4715 34.2625 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 91.21 seriola_lalandi_dorsalis ENSSLDP00000027819 94.9095 90.3846 ENSG00000108424 homo_sapiens ENSP00000290158 96.4612 91.6667 labrus_bergylta ENSLBEP00000034317 94.7309 90.0224 ENSG00000108424 homo_sapiens ENSP00000290158 27.6256 26.3699 labrus_bergylta ENSLBEP00000009053 96.4143 92.0319 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.6941 pundamilia_nyererei ENSPNYP00000023491 93.1223 88.6463 ENSG00000108424 homo_sapiens ENSP00000290158 94.7489 89.9543 mastacembelus_armatus ENSMAMP00000036310 89.7297 85.1892 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.9224 stegastes_partitus ENSSPAP00000025664 97.3744 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 89.4977 84.1324 oncorhynchus_tshawytscha ENSOTSP00005038106 90.6358 85.2023 ENSG00000108424 homo_sapiens ENSP00000290158 93.6073 88.4703 oncorhynchus_tshawytscha ENSOTSP00005067515 96.3572 91.0693 ENSG00000108424 homo_sapiens ENSP00000290158 97.3744 92.9224 acanthochromis_polyacanthus ENSAPOP00000017303 97.3744 92.9224 ENSG00000108424 homo_sapiens ENSP00000290158 99.3151 97.831 aquila_chrysaetos_chrysaetos ENSACCP00020007894 99.3151 97.831 ENSG00000108424 homo_sapiens ENSP00000290158 32.0776 30.8219 nothobranchius_furzeri ENSNFUP00015031030 96.5636 92.7835 ENSG00000108424 homo_sapiens ENSP00000290158 18.379 17.2374 nothobranchius_furzeri ENSNFUP00015032959 88.4615 82.967 ENSG00000108424 homo_sapiens ENSP00000290158 32.1918 30.8219 cyprinodon_variegatus ENSCVAP00000026690 96.9072 92.7835 ENSG00000108424 homo_sapiens ENSP00000290158 18.6073 17.5799 cyprinodon_variegatus ENSCVAP00000010337 91.0615 86.0335 ENSG00000108424 homo_sapiens ENSP00000290158 93.8356 89.1553 denticeps_clupeoides ENSDCDP00000024952 89.6401 85.169 ENSG00000108424 homo_sapiens ENSP00000290158 89.726 84.3607 larimichthys_crocea ENSLCRP00005060206 88.7133 83.4086 ENSG00000108424 homo_sapiens ENSP00000290158 96.0046 90.2968 takifugu_rubripes ENSTRUP00000001283 96.0046 90.2968 ENSG00000108424 homo_sapiens ENSP00000290158 52.8539 51.484 ficedula_albicollis ENSFALP00000033834 96.2578 93.763 ENSG00000108424 homo_sapiens ENSP00000290158 90.7534 84.3607 hippocampus_comes ENSHCOP00000001140 89.527 83.2207 ENSG00000108424 homo_sapiens ENSP00000290158 97.032 92.4658 cyprinus_carpio_carpio ENSCCRP00000092715 88.634 84.463 ENSG00000108424 homo_sapiens ENSP00000290158 94.5205 89.6119 cyprinus_carpio_carpio ENSCCRP00000091059 90.7895 86.0746 ENSG00000108424 homo_sapiens ENSP00000290158 99.4292 97.6027 coturnix_japonica ENSCJPP00005000824 99.4292 97.6027 ENSG00000108424 homo_sapiens ENSP00000290158 97.1461 92.0091 poecilia_latipinna ENSPLAP00000024582 97.1461 92.0091 ENSG00000108424 homo_sapiens ENSP00000290158 94.6347 89.3836 sinocyclocheilus_grahami ENSSGRP00000057659 83.9919 79.3313 ENSG00000108424 homo_sapiens ENSP00000290158 94.7489 89.6119 sinocyclocheilus_grahami ENSSGRP00000037592 87.7378 82.981 ENSG00000108424 homo_sapiens ENSP00000290158 96.347 91.6667 maylandia_zebra ENSMZEP00005005969 96.2372 91.5621 ENSG00000108424 homo_sapiens ENSP00000290158 96.4612 90.5251 tetraodon_nigroviridis ENSTNIP00000009263 96.4612 90.5251 ENSG00000108424 homo_sapiens ENSP00000290158 20.2055 18.9498 tetraodon_nigroviridis ENSTNIP00000022855 98.3333 92.2222 ENSG00000108424 homo_sapiens ENSP00000290158 97.831 93.0365 paramormyrops_kingsleyae ENSPKIP00000040742 97.7195 92.9304 ENSG00000108424 homo_sapiens ENSP00000290158 97.7169 93.6073 scleropages_formosus ENSSFOP00015066083 97.7169 93.6073 ENSG00000108424 homo_sapiens ENSP00000290158 93.9498 89.0411 leptobrachium_leishanense ENSLLEP00000038682 95.365 90.3824 ENSG00000108424 homo_sapiens ENSP00000290158 95.7763 91.21 scophthalmus_maximus ENSSMAP00000069235 82.4975 78.5644 ENSG00000108424 homo_sapiens ENSP00000290158 97.2603 92.8082 oryzias_melastigma ENSOMEP00000019196 94.9833 90.6355
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005576 located_in extracellular region 1 TAS Homo_sapiens(9606) Component GO:0005634 is_active_in nucleus 1 IBA Homo_sapiens(9606) Component GO:0005635 located_in nuclear envelope 1 IDA Homo_sapiens(9606) Component GO:0005643 part_of nuclear pore 1 TAS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 3 IDA,NAS,TAS Homo_sapiens(9606) Component GO:0005737 is_active_in cytoplasm 3 IBA,IDA,ISS Homo_sapiens(9606) Component GO:0005829 located_in cytosol 3 IDA,NAS,TAS Homo_sapiens(9606) Component GO:0006404 involved_in RNA import into nucleus 1 IDA Homo_sapiens(9606) Process GO:0006606 involved_in protein import into nucleus 5 IBA,IDA,IMP,ISS Homo_sapiens(9606) Process GO:0006607 involved_in NLS-bearing protein import into nucleus 2 IDA,ISS Homo_sapiens(9606) Process GO:0006610 involved_in ribosomal protein import into nucleus 1 IDA Homo_sapiens(9606) Process GO:0007079 involved_in mitotic chromosome movement towards spindle pole 1 IMP Homo_sapiens(9606) Process GO:0007080 involved_in mitotic metaphase plate congression 1 IMP Homo_sapiens(9606) Process GO:0008139 enables nuclear localization sequence binding 1 IBA Homo_sapiens(9606) Function GO:0008270 enables zinc ion binding 1 TAS Homo_sapiens(9606) Function GO:0010494 located_in cytoplasmic stress granule 1 ISS Homo_sapiens(9606) Component GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0019899 enables enzyme binding 1 IPI Homo_sapiens(9606) Function GO:0019904 enables protein domain specific binding 1 IPI Homo_sapiens(9606) Function GO:0030953 involved_in astral microtubule organization 1 IMP Homo_sapiens(9606) Process GO:0031267 enables small GTPase binding 1 IEA Homo_sapiens(9606) Function GO:0031291 involved_in Ran protein signal transduction 1 IMP Homo_sapiens(9606) Process GO:0031965 located_in nuclear membrane 1 IDA Homo_sapiens(9606) Component GO:0035580 located_in specific granule lumen 1 TAS Homo_sapiens(9606) Component GO:0040001 involved_in establishment of mitotic spindle localization 1 IMP Homo_sapiens(9606) Process GO:0042564 part_of NLS-dependent protein nuclear import complex 2 IPI,ISS Homo_sapiens(9606) Component GO:0045184 involved_in establishment of protein localization 1 IMP Homo_sapiens(9606) Process GO:0051879 enables Hsp90 protein binding 1 IEA Homo_sapiens(9606) Function GO:0061608 enables nuclear import signal receptor activity 3 IBA,IDA,ISS Homo_sapiens(9606) Function GO:0061676 enables importin-alpha family protein binding 1 IEA Homo_sapiens(9606) Function GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:0071782 located_in endoplasmic reticulum tubular network 1 IDA Homo_sapiens(9606) Component GO:0090307 involved_in mitotic spindle assembly 1 IMP Homo_sapiens(9606) Process GO:1904813 located_in ficolin-1-rich granule lumen 1 TAS Homo_sapiens(9606) Component
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