RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000108064	Gene ID	7019	Accession	11741
Symbol	TFAM	Alias	TCF6;MTTF1;MTTFA;TCF6L1;TCF6L2;TCF6L3;MTDPS15	Full Name	transcription factor A, mitochondrial
Status	Confidence	Length	13811 bases	Strand	Plus strand
Position	10 : 58385410 - 58399220	RNA binding domain	N.A.
Summary	This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
26545237	Mitochondrial Transcription Factor A (TFAM) Binds to RNA Containing 4-Way Junctions and Mitochondrial tRNA.	A Timothy Brown	2015-01-01	PloS one
27814609	Mitochondrial nucleic acid binding proteins associated with diseases.	Takeshi Uchiumi	2017-01-01	Frontiers in bioscience (Landmark edition)
34295920	Selective Neuron Vulnerability in Common and Rare Diseases-Mitochondria in the Focus.	Thomas Paß	2021-01-01	Frontiers in molecular biosciences
29856906	HuR stabilizes TFAM mRNA in an ATM/p38-dependent manner in ionizing irradiated cancer cells.	Rui Zhang	2018-08-01	Cancer science
32824374	Mitochondrial HMG-Box Containing Proteins: From Biochemical Properties to the Roles in Human Diseases.	Veronika Vozáriková	2020-08-16	Biomolecules
37627512	Mitochondrial Volume Regulation and Swelling Mechanisms in Cardiomyocytes.	R Xavier Chapa-Dubocq	2023-07-28	Antioxidants (Basel, Switzerland)
31195723	Organization of DNA in Mammalian Mitochondria.	Géraldine Farge	2019-06-05	International journal of molecular sciences
21854988	The human mitochondrial transcriptome.	R Tim Mercer	2011-08-19	Cell
27903899	Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation.	Aparna Ramachandran	2017-01-25	Nucleic acids research
37401363	Uncharacterized protein C17orf80 - a novel interactor of human mitochondrial nucleoids.	Alisa Potter	2023-08-01	Journal of cell science
36838782	Structural and Molecular Basis for Mitochondrial DNA Replication and Transcription in Health and Antiviral Drug Toxicity.	Joon Park	2023-02-14	Molecules (Basel, Switzerland)
23650593	The manner in which DNA is packaged with TFAM has an impact on transcription activation and inhibition.	Ryo Furukawa	2012-01-01	FEBS open bio
28276514	The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein.	Sébastien Lyonnais	2017-03-09	Scientific reports

Name	Transcript ID	bp	Protein	Translation ID
TFAM-204	ENST00000487519	5025	246aa	ENSP00000420588
TFAM-202	ENST00000373899	1121	No protein	-
TFAM-201	ENST00000373895	973	214aa	ENSP00000363002
TFAM-203	ENST00000395377	663	219aa	ENSP00000378776

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
31201	Erythrocyte Indices	1.7820000E-005	-
31211	Erythrocyte Indices	1.7770000E-005	-
74445	Refraction, Ocular	2E-13	23396134
96773	Body Height	6E-6	23456168
104015	Migraine Disorders	2E-6	23793025

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000108064	homo_sapiens	ENSP00000328269	16.4038	7.88644	homo_sapiens	ENSP00000420588	21.1382	10.1626
ENSG00000108064	homo_sapiens	ENSP00000359393	45.5	25.5	homo_sapiens	ENSP00000420588	36.9919	20.7317
ENSG00000108064	homo_sapiens	ENSP00000505691	38.7097	19.8925	homo_sapiens	ENSP00000420588	29.2683	15.0407
ENSG00000108064	homo_sapiens	ENSP00000296503	41.6268	21.5311	homo_sapiens	ENSP00000420588	35.3659	18.2927
ENSG00000108064	homo_sapiens	ENSP00000485108	14.2494	6.61578	homo_sapiens	ENSP00000420588	22.7642	10.5691
ENSG00000108064	homo_sapiens	ENSP00000354842	13.1179	5.51331	homo_sapiens	ENSP00000420588	28.0488	11.7886
ENSG00000108064	homo_sapiens	ENSP00000344724	12.6482	6.52174	homo_sapiens	ENSP00000420588	26.0163	13.4146
ENSG00000108064	homo_sapiens	ENSP00000343023	9.03955	4.0678	homo_sapiens	ENSP00000420588	32.5203	14.6341
ENSG00000108064	homo_sapiens	ENSP00000219746	11.6319	5.38194	homo_sapiens	ENSP00000420588	27.2358	12.6016
ENSG00000108064	homo_sapiens	ENSP00000397911	9.48276	3.96552	homo_sapiens	ENSP00000420588	22.3577	9.34959
ENSG00000108064	homo_sapiens	ENSP00000508468	42.1801	21.8009	homo_sapiens	ENSP00000420588	36.1789	18.6992
ENSG00000108064	homo_sapiens	ENSP00000345347	42.3256	22.7907	homo_sapiens	ENSP00000420588	36.9919	19.9187
ENSG00000108064	homo_sapiens	ENSP00000216106	13.1448	7.15474	homo_sapiens	ENSP00000420588	32.1138	17.4797
ENSG00000108064	homo_sapiens	ENSP00000390669	8.63874	4.45026	homo_sapiens	ENSP00000420588	26.8293	13.8211
ENSG00000108064	homo_sapiens	ENSP00000323967	11.6788	6.32603	homo_sapiens	ENSP00000420588	19.5122	10.5691
ENSG00000108064	homo_sapiens	ENSP00000258381	8.13464	3.78682	homo_sapiens	ENSP00000420588	23.5772	10.9756
ENSG00000108064	homo_sapiens	ENSP00000375899	7.49712	3.22953	homo_sapiens	ENSP00000420588	26.4228	11.3821
ENSG00000108064	homo_sapiens	ENSP00000278412	7.19323	3.24401	homo_sapiens	ENSP00000420588	20.7317	9.34959
ENSG00000108064	homo_sapiens	ENSP00000336856	14.121	6.34006	homo_sapiens	ENSP00000420588	19.9187	8.94309
ENSG00000108064	homo_sapiens	ENSP00000393080	10.628	5.31401	homo_sapiens	ENSP00000420588	26.8293	13.4146

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000108064	homo_sapiens	ENSP00000420588	96.3415	93.9024	nomascus_leucogenys	ENSNLEP00000014937	98.3402	95.8506
ENSG00000108064	homo_sapiens	ENSP00000420588	97.561	97.1545	pan_paniscus	ENSPPAP00000014082	100	99.5833
ENSG00000108064	homo_sapiens	ENSP00000420588	98.7805	95.935	pongo_abelii	ENSPPYP00000028261	85.5634	83.0986
ENSG00000108064	homo_sapiens	ENSP00000420588	86.5854	83.3333	pan_troglodytes	ENSPTRP00000062017	92.6087	89.1304
ENSG00000108064	homo_sapiens	ENSP00000420588	100	100	gorilla_gorilla	ENSGGOP00000041705	88.4892	88.4892
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	40.2439	ornithorhynchus_anatinus	ENSOANP00000007315	59.3156	37.6426
ENSG00000108064	homo_sapiens	ENSP00000420588	65.4472	43.4959	ornithorhynchus_anatinus	ENSOANP00000045956	60.9848	40.5303
ENSG00000108064	homo_sapiens	ENSP00000420588	65.8537	43.4959	sarcophilus_harrisii	ENSSHAP00000038245	63.035	41.6342
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	41.8699	notamacropus_eugenii	ENSMEUP00000008038	72.3005	48.3568
ENSG00000108064	homo_sapiens	ENSP00000420588	49.187	40.6504	choloepus_hoffmanni	ENSCHOP00000000500	49.187	40.6504
ENSG00000108064	homo_sapiens	ENSP00000420588	82.1138	64.2276	dasypus_novemcinctus	ENSDNOP00000033570	72.1429	56.4286
ENSG00000108064	homo_sapiens	ENSP00000420588	37.8049	31.3008	dasypus_novemcinctus	ENSDNOP00000000407	87.7358	72.6415
ENSG00000108064	homo_sapiens	ENSP00000420588	41.8699	31.3008	erinaceus_europaeus	ENSEEUP00000005560	72.028	53.8462
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	71.5447	callithrix_jacchus	ENSCJAP00000019582	85.83	71.2551
ENSG00000108064	homo_sapiens	ENSP00000420588	95.1219	87.3984	cercocebus_atys	ENSCATP00000009154	94.3548	86.6936
ENSG00000108064	homo_sapiens	ENSP00000420588	95.5285	86.1789	macaca_fascicularis	ENSMFAP00000007206	95.1417	85.83
ENSG00000108064	homo_sapiens	ENSP00000420588	96.3415	86.5854	macaca_mulatta	ENSMMUP00000026067	95.5645	85.8871
ENSG00000108064	homo_sapiens	ENSP00000420588	96.3415	86.1789	macaca_nemestrina	ENSMNEP00000011740	95.5645	85.4839
ENSG00000108064	homo_sapiens	ENSP00000420588	93.0894	83.7398	papio_anubis	ENSPANP00000009841	96.6245	86.9198
ENSG00000108064	homo_sapiens	ENSP00000420588	95.935	86.5854	papio_anubis	ENSPANP00000020502	95.935	86.5854
ENSG00000108064	homo_sapiens	ENSP00000420588	75.2033	63.8211	papio_anubis	ENSPANP00000060907	69.2884	58.8015
ENSG00000108064	homo_sapiens	ENSP00000420588	95.5285	86.9919	mandrillus_leucophaeus	ENSMLEP00000015115	94.7581	86.2903
ENSG00000108064	homo_sapiens	ENSP00000420588	82.1138	66.2602	tursiops_truncatus	ENSTTRP00000008768	83.4711	67.3554
ENSG00000108064	homo_sapiens	ENSP00000420588	84.9594	70.7317	vulpes_vulpes	ENSVVUP00000011289	85.3061	71.0204
ENSG00000108064	homo_sapiens	ENSP00000420588	76.8293	61.7886	mus_spretus	MGP_SPRETEiJ_P0024468	77.7778	62.5514
ENSG00000108064	homo_sapiens	ENSP00000420588	85.7724	71.9512	equus_asinus	ENSEASP00005035434	85.7724	71.9512
ENSG00000108064	homo_sapiens	ENSP00000420588	87.3984	70.3252	capra_hircus	ENSCHIP00000013167	87.3984	70.3252
ENSG00000108064	homo_sapiens	ENSP00000420588	84.9594	70.3252	loxodonta_africana	ENSLAFP00000010781	85.3061	70.6122
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	73.1707	panthera_leo	ENSPLOP00000029706	86.1789	73.1707
ENSG00000108064	homo_sapiens	ENSP00000420588	86.5854	73.1707	ailuropoda_melanoleuca	ENSAMEP00000010813	86.5854	73.1707
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	71.1382	bos_indicus_hybrid	ENSBIXP00005046696	88.6179	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	74.7967	60.9756	oryctolagus_cuniculus	ENSOCUP00000012385	65.9498	53.7634
ENSG00000108064	homo_sapiens	ENSP00000420588	85.3659	71.5447	canis_lupus_familiaris	ENSCAFP00845002726	85.3659	71.5447
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	73.1707	panthera_pardus	ENSPPRP00000001644	86.1789	73.1707
ENSG00000108064	homo_sapiens	ENSP00000420588	84.1463	71.1382	marmota_marmota_marmota	ENSMMMP00000002462	84.1463	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	84.5528	69.5122	balaenoptera_musculus	ENSBMSP00010030896	86.6667	71.25
ENSG00000108064	homo_sapiens	ENSP00000420588	71.9512	56.0976	cavia_porcellus	ENSCPOP00000029376	75.3191	58.7234
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	73.1707	felis_catus	ENSFCAP00000029275	86.1789	73.1707
ENSG00000108064	homo_sapiens	ENSP00000420588	86.5854	72.3577	ursus_americanus	ENSUAMP00000000248	86.5854	72.3577
ENSG00000108064	homo_sapiens	ENSP00000420588	63.0081	41.4634	monodelphis_domestica	ENSMODP00000020143	59.8456	39.3822
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	71.1382	bison_bison_bison	ENSBBBP00000017269	88.6179	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	84.9594	68.6992	monodon_monoceros	ENSMMNP00015015225	87.0833	70.4167
ENSG00000108064	homo_sapiens	ENSP00000420588	87.8049	71.9512	sus_scrofa	ENSSSCP00000042490	87.8049	71.9512
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	72.7642	microcebus_murinus	ENSMICP00000009341	88.6179	72.7642
ENSG00000108064	homo_sapiens	ENSP00000420588	74.3902	54.4715	octodon_degus	ENSODEP00000001027	80.2632	58.7719
ENSG00000108064	homo_sapiens	ENSP00000420588	75.2033	54.4715	jaculus_jaculus	ENSJJAP00000012482	76.7635	55.6017
ENSG00000108064	homo_sapiens	ENSP00000420588	88.2114	71.1382	ovis_aries_rambouillet	ENSOARP00020030460	88.2114	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	86.5854	72.3577	ursus_maritimus	ENSUMAP00000008527	86.5854	72.3577
ENSG00000108064	homo_sapiens	ENSP00000420588	77.6423	63.4146	ochotona_princeps	ENSOPRP00000002362	78.6008	64.1975
ENSG00000108064	homo_sapiens	ENSP00000420588	84.5528	68.2927	delphinapterus_leucas	ENSDLEP00000012987	86.6667	70
ENSG00000108064	homo_sapiens	ENSP00000420588	74.7967	58.5366	delphinapterus_leucas	ENSDLEP00000002114	80.7018	63.1579
ENSG00000108064	homo_sapiens	ENSP00000420588	84.1463	67.8862	physeter_catodon	ENSPCTP00005020841	86.25	69.5833
ENSG00000108064	homo_sapiens	ENSP00000420588	76.0163	60.1626	mus_caroli	MGP_CAROLIEiJ_P0023323	76.9547	60.9053
ENSG00000108064	homo_sapiens	ENSP00000420588	77.2358	61.3821	mus_musculus	ENSMUSP00000090086	78.1893	62.1399
ENSG00000108064	homo_sapiens	ENSP00000420588	81.7073	64.6341	dipodomys_ordii	ENSDORP00000013173	82.0408	64.898
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	72.7642	mustela_putorius_furo	ENSMPUP00000010332	86.1789	72.7642
ENSG00000108064	homo_sapiens	ENSP00000420588	79.2683	66.2602	aotus_nancymaae	ENSANAP00000019244	89.8617	75.1152
ENSG00000108064	homo_sapiens	ENSP00000420588	85.7724	70.3252	saimiri_boliviensis_boliviensis	ENSSBOP00000016190	85.4251	70.0405
ENSG00000108064	homo_sapiens	ENSP00000420588	86.5854	71.9512	vicugna_pacos	ENSVPAP00000006457	86.9388	72.2449
ENSG00000108064	homo_sapiens	ENSP00000420588	95.5285	89.0244	chlorocebus_sabaeus	ENSCSAP00000003557	94.7581	88.3064
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	54.065	tupaia_belangeri	ENSTBEP00000011359	77.7778	67.1717
ENSG00000108064	homo_sapiens	ENSP00000420588	84.1463	68.6992	phocoena_sinus	ENSPSNP00000025906	86.25	70.4167
ENSG00000108064	homo_sapiens	ENSP00000420588	86.9919	74.3902	carlito_syrichta	ENSTSYP00000010357	86.9919	74.3902
ENSG00000108064	homo_sapiens	ENSP00000420588	81.3008	70.3252	carlito_syrichta	ENSTSYP00000021411	85.4701	73.9316
ENSG00000108064	homo_sapiens	ENSP00000420588	79.2683	67.4797	panthera_tigris_altaica	ENSPTIP00000019884	83.3333	70.9402
ENSG00000108064	homo_sapiens	ENSP00000420588	77.6423	62.1951	rattus_norvegicus	ENSRNOP00000000753	78.2787	62.7049
ENSG00000108064	homo_sapiens	ENSP00000420588	89.0244	73.9837	prolemur_simus	ENSPSMP00000034573	89.0244	73.9837
ENSG00000108064	homo_sapiens	ENSP00000420588	79.2683	61.7886	microtus_ochrogaster	ENSMOCP00000015347	79.918	62.2951
ENSG00000108064	homo_sapiens	ENSP00000420588	52.0325	42.6829	sorex_araneus	ENSSARP00000008890	88.8889	72.9167
ENSG00000108064	homo_sapiens	ENSP00000420588	78.4553	63.0081	peromyscus_maniculatus_bairdii	ENSPEMP00000027166	79.0984	63.5246
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	71.1382	bos_mutus	ENSBMUP00000009097	88.6179	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	76.8293	61.7886	mus_spicilegus	ENSMSIP00000033999	77.7778	62.5514
ENSG00000108064	homo_sapiens	ENSP00000420588	76.4228	58.9431	cricetulus_griseus_chok1gshd	ENSCGRP00001020071	77.3663	59.6708
ENSG00000108064	homo_sapiens	ENSP00000420588	87.3984	71.5447	pteropus_vampyrus	ENSPVAP00000006977	87.7551	71.8367
ENSG00000108064	homo_sapiens	ENSP00000420588	85.7724	65.0406	myotis_lucifugus	ENSMLUP00000005264	86.1225	65.3061
ENSG00000108064	homo_sapiens	ENSP00000420588	58.9431	40.2439	vombatus_ursinus	ENSVURP00010001707	69.7115	47.5962
ENSG00000108064	homo_sapiens	ENSP00000420588	86.5854	70.3252	rhinolophus_ferrumequinum	ENSRFEP00010033345	86.5854	70.3252
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	72.7642	neovison_vison	ENSNVIP00000030388	86.1789	72.7642
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	71.1382	bos_taurus	ENSBTAP00000052192	88.6179	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	73.1707	51.2195	heterocephalus_glaber_female	ENSHGLP00000034804	73.1707	51.2195
ENSG00000108064	homo_sapiens	ENSP00000420588	94.7154	89.8374	rhinopithecus_bieti	ENSRBIP00000015533	92.8287	88.0478
ENSG00000108064	homo_sapiens	ENSP00000420588	85.3659	71.5447	canis_lupus_dingo	ENSCAFP00020034694	85.3659	71.5447
ENSG00000108064	homo_sapiens	ENSP00000420588	84.9594	71.5447	sciurus_vulgaris	ENSSVLP00005003478	83.2669	70.1195
ENSG00000108064	homo_sapiens	ENSP00000420588	85.3659	71.9512	sciurus_vulgaris	ENSSVLP00005010661	85.0202	71.6599
ENSG00000108064	homo_sapiens	ENSP00000420588	85.3659	71.9512	sciurus_vulgaris	ENSSVLP00005024505	84.6774	71.371
ENSG00000108064	homo_sapiens	ENSP00000420588	40.2439	23.5772	phascolarctos_cinereus	ENSPCIP00000039334	38.3721	22.4806
ENSG00000108064	homo_sapiens	ENSP00000420588	57.7236	46.3415	procavia_capensis	ENSPCAP00000014012	57.9592	46.5306
ENSG00000108064	homo_sapiens	ENSP00000420588	78.8618	58.9431	nannospalax_galili	ENSNGAP00000023097	79.5082	59.4262
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	71.1382	bos_grunniens	ENSBGRP00000030474	88.6179	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	77.2358	56.5041	chinchilla_lanigera	ENSCLAP00000014459	76.9231	56.2753
ENSG00000108064	homo_sapiens	ENSP00000420588	88.2114	69.9187	cervus_hanglu_yarkandensis	ENSCHYP00000021546	88.2114	69.9187
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	71.1382	catagonus_wagneri	ENSCWAP00000028729	86.1789	71.1382
ENSG00000108064	homo_sapiens	ENSP00000420588	83.7398	70.3252	ictidomys_tridecemlineatus	ENSSTOP00000001454	83.7398	70.3252
ENSG00000108064	homo_sapiens	ENSP00000420588	82.9268	68.2927	otolemur_garnettii	ENSOGAP00000013384	82.9268	68.2927
ENSG00000108064	homo_sapiens	ENSP00000420588	86.1789	73.1707	cebus_imitator	ENSCCAP00000039525	85.1406	72.2892
ENSG00000108064	homo_sapiens	ENSP00000420588	84.1463	70.7317	urocitellus_parryii	ENSUPAP00010000824	84.1463	70.7317
ENSG00000108064	homo_sapiens	ENSP00000420588	88.6179	69.9187	moschus_moschiferus	ENSMMSP00000032796	88.6179	69.9187
ENSG00000108064	homo_sapiens	ENSP00000420588	95.935	91.0569	rhinopithecus_roxellana	ENSRROP00000018489	95.1613	90.3226
ENSG00000108064	homo_sapiens	ENSP00000420588	95.5285	91.4634	rhinopithecus_roxellana	ENSRROP00000005923	94.7581	90.7258
ENSG00000108064	homo_sapiens	ENSP00000420588	75.6098	60.5691	mus_pahari	MGP_PahariEiJ_P0086488	76.5432	61.3169
ENSG00000108064	homo_sapiens	ENSP00000420588	87.3984	72.7642	propithecus_coquereli	ENSPCOP00000022692	87.3984	72.7642
ENSG00000108064	homo_sapiens	ENSP00000420588	16.6667	7.31707	caenorhabditis_elegans	T20B12.8.1	5.88235	2.5825
ENSG00000108064	homo_sapiens	ENSP00000420588	14.2276	6.50407	caenorhabditis_elegans	C32F10.5.1	5.07983	2.32221
ENSG00000108064	homo_sapiens	ENSP00000420588	22.7642	12.6016	ciona_intestinalis	ENSCINP00000023739	8.8189	4.88189
ENSG00000108064	homo_sapiens	ENSP00000420588	54.4715	33.7398	petromyzon_marinus	ENSPMAP00000007158	47.0175	29.1228
ENSG00000108064	homo_sapiens	ENSP00000420588	47.561	29.2683	eptatretus_burgeri	ENSEBUP00000003039	43.985	27.0677
ENSG00000108064	homo_sapiens	ENSP00000420588	56.0976	35.7724	callorhinchus_milii	ENSCMIP00000047498	50.7353	32.3529
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	41.0569	latimeria_chalumnae	ENSLACP00000007086	56.3177	36.4621
ENSG00000108064	homo_sapiens	ENSP00000420588	66.6667	41.4634	lepisosteus_oculatus	ENSLOCP00000007795	55.9727	34.8123
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	41.4634	clupea_harengus	ENSCHAP00000025172	54.417	36.0424
ENSG00000108064	homo_sapiens	ENSP00000420588	60.5691	39.4309	danio_rerio	ENSDARP00000086442	53.7906	35.0181
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	38.6179	carassius_auratus	ENSCARP00000051952	55.7971	34.4203
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	39.4309	carassius_auratus	ENSCARP00000061125	55.7971	35.1449
ENSG00000108064	homo_sapiens	ENSP00000420588	58.9431	34.1463	astyanax_mexicanus	ENSAMXP00000052796	46.9256	27.1845
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	39.4309	ictalurus_punctatus	ENSIPUP00000012674	55.1237	34.2756
ENSG00000108064	homo_sapiens	ENSP00000420588	52.8455	33.7398	esox_lucius	ENSELUP00000018141	46.9314	29.9639
ENSG00000108064	homo_sapiens	ENSP00000420588	61.7886	39.0244	electrophorus_electricus	ENSEEEP00000003585	55.0725	34.7826
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	36.9919	oncorhynchus_kisutch	ENSOKIP00005010378	55.5944	31.8182
ENSG00000108064	homo_sapiens	ENSP00000420588	51.626	27.6423	oncorhynchus_kisutch	ENSOKIP00005060659	43.6426	23.3677
ENSG00000108064	homo_sapiens	ENSP00000420588	65.0406	37.8049	oncorhynchus_mykiss	ENSOMYP00000110462	55.9441	32.5175
ENSG00000108064	homo_sapiens	ENSP00000420588	65.0406	37.8049	oncorhynchus_mykiss	ENSOMYP00000130628	56.338	32.7465
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	35.7724	salmo_salar	ENSSSAP00000039462	58.3969	33.5878
ENSG00000108064	homo_sapiens	ENSP00000420588	51.2195	26.8293	salmo_salar	ENSSSAP00000146386	47.3684	24.812
ENSG00000108064	homo_sapiens	ENSP00000420588	59.7561	34.9594	salmo_salar	ENSSSAP00000039417	56.5385	33.0769
ENSG00000108064	homo_sapiens	ENSP00000420588	49.5935	27.6423	salmo_trutta	ENSSTUP00000104528	30.4239	16.9576
ENSG00000108064	homo_sapiens	ENSP00000420588	49.5935	27.6423	salmo_trutta	ENSSTUP00000077448	28.7059	16
ENSG00000108064	homo_sapiens	ENSP00000420588	60.1626	36.1789	gadus_morhua	ENSGMOP00000016996	51.3889	30.9028
ENSG00000108064	homo_sapiens	ENSP00000420588	44.3089	24.3902	fundulus_heteroclitus	ENSFHEP00000002306	61.236	33.7079
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	35.3659	poecilia_reticulata	ENSPREP00000005388	48.773	26.6871
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	35.3659	xiphophorus_maculatus	ENSXMAP00000034417	53.4247	29.7945
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	39.4309	oryzias_latipes	ENSORLP00000035087	50.3289	31.9079
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	37.8049	cyclopterus_lumpus	ENSCLMP00005035230	52.381	31.6327
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	39.8374	oreochromis_niloticus	ENSONIP00000039747	54.3554	34.1463
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.8374	haplochromis_burtoni	ENSHBUP00000018334	54.1096	33.5616
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.8374	astatotilapia_calliptera	ENSACLP00000000259	54.1096	33.5616
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	36.5854	sparus_aurata	ENSSAUP00010021507	52.7397	30.8219
ENSG00000108064	homo_sapiens	ENSP00000420588	42.6829	25.2033	lates_calcarifer	ENSLCAP00010037541	45.6522	26.9565
ENSG00000108064	homo_sapiens	ENSP00000420588	65.8537	43.4959	chrysemys_picta_bellii	ENSCPBP00000010227	58.2734	38.4892
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	41.0569	sphenodon_punctatus	ENSSPUP00000003207	57.7778	37.4074
ENSG00000108064	homo_sapiens	ENSP00000420588	57.7236	39.0244	crocodylus_porosus	ENSCPRP00005013819	51.4493	34.7826
ENSG00000108064	homo_sapiens	ENSP00000420588	41.0569	27.2358	laticauda_laticaudata	ENSLLTP00000017591	60.479	40.1198
ENSG00000108064	homo_sapiens	ENSP00000420588	54.878	35.7724	notechis_scutatus	ENSNSUP00000022194	55.3279	36.0656
ENSG00000108064	homo_sapiens	ENSP00000420588	54.4715	35.7724	pseudonaja_textilis	ENSPTXP00000009774	54.918	36.0656
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.4309	anas_platyrhynchos_platyrhynchos	ENSAPLP00000031434	41.6887	25.5937
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.8374	gallus_gallus	ENSGALP00010012264	60.3053	37.4046
ENSG00000108064	homo_sapiens	ENSP00000420588	54.065	30.8943	serinus_canaria	ENSSCAP00000004776	53.4137	30.5221
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	39.0244	parus_major	ENSPMJP00000011642	53.1034	33.1034
ENSG00000108064	homo_sapiens	ENSP00000420588	65.0406	43.0894	anolis_carolinensis	ENSACAP00000004226	58.3942	38.6861
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	39.8374	neolamprologus_brichardi	ENSNBRP00000030197	53	32.6667
ENSG00000108064	homo_sapiens	ENSP00000420588	52.0325	30.4878	naja_naja	ENSNNAP00000024982	32.9049	19.2802
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	39.0244	podarcis_muralis	ENSPMRP00000008520	52.5597	32.7645
ENSG00000108064	homo_sapiens	ENSP00000420588	48.374	28.0488	geospiza_fortis	ENSGFOP00000016230	63.9785	37.0968
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	38.2114	taeniopygia_guttata	ENSTGUP00000005327	54.1096	32.1918
ENSG00000108064	homo_sapiens	ENSP00000420588	58.9431	36.5854	erpetoichthys_calabaricus	ENSECRP00000003320	51.6014	32.0285
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	41.0569	kryptolebias_marmoratus	ENSKMAP00000021730	55.8304	35.689
ENSG00000108064	homo_sapiens	ENSP00000420588	61.7886	39.0244	salvator_merianae	ENSSMRP00000016473	55.6777	35.1648
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	38.2114	oryzias_javanicus	ENSOJAP00000010586	52.349	31.5436
ENSG00000108064	homo_sapiens	ENSP00000420588	39.8374	21.5447	amphilophus_citrinellus	ENSACIP00000017399	64.0523	34.6405
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	38.2114	amphilophus_citrinellus	ENSACIP00000004695	52.9412	32.526
ENSG00000108064	homo_sapiens	ENSP00000420588	59.7561	36.9919	dicentrarchus_labrax	ENSDLAP00005048402	56.1069	34.7328
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	35.7724	amphiprion_percula	ENSAPEP00000022633	52.381	29.932
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	39.4309	oryzias_sinensis	ENSOSIP00000049239	50.8251	32.0132
ENSG00000108064	homo_sapiens	ENSP00000420588	63.8211	41.8699	pelodiscus_sinensis	ENSPSIP00000015691	58.8015	38.5768
ENSG00000108064	homo_sapiens	ENSP00000420588	66.6667	44.3089	gopherus_evgoodei	ENSGEVP00005013711	58.7814	39.0681
ENSG00000108064	homo_sapiens	ENSP00000420588	67.4797	44.3089	chelonoidis_abingdonii	ENSCABP00000016632	59.7122	39.2086
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	36.5854	seriola_dumerili	ENSSDUP00000022036	52.0408	30.6122
ENSG00000108064	homo_sapiens	ENSP00000420588	60.5691	37.3984	cottoperca_gobio	ENSCGOP00000052904	54.7794	33.8235
ENSG00000108064	homo_sapiens	ENSP00000420588	61.3821	37.3984	struthio_camelus_australis	ENSSCUP00000000882	59.2157	36.0784
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.8374	anser_brachyrhynchus	ENSABRP00000026386	59.6226	36.9811
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	38.6179	gasterosteus_aculeatus	ENSGACP00000020354	58.3333	35.9848
ENSG00000108064	homo_sapiens	ENSP00000420588	58.5366	36.1789	cynoglossus_semilaevis	ENSCSEP00000024283	52.9412	32.7206
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	35.3659	poecilia_formosa	ENSPFOP00000011118	53.3557	29.1946
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	35.7724	myripristis_murdjan	ENSMMDP00005053370	52.027	29.7297
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.4309	sander_lucioperca	ENSSLUP00000047874	53.7415	32.9932
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	38.2114	strigops_habroptila	ENSSHBP00005014723	58.3333	35.6061
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	36.5854	amphiprion_ocellaris	ENSAOCP00000022302	53.0612	30.6122
ENSG00000108064	homo_sapiens	ENSP00000420588	67.0732	43.9024	terrapene_carolina_triunguis	ENSTMTP00000001106	59.3525	38.8489
ENSG00000108064	homo_sapiens	ENSP00000420588	49.187	28.4553	hucho_hucho	ENSHHUP00000062982	63.6842	36.8421
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	35.7724	betta_splendens	ENSBSLP00000013380	52.8814	29.8305
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	36.1789	betta_splendens	ENSBSLP00000013292	53.5593	30.1695
ENSG00000108064	homo_sapiens	ENSP00000420588	66.2602	39.8374	pygocentrus_nattereri	ENSPNAP00000031497	56.993	34.2657
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	36.1789	anabas_testudineus	ENSATEP00000033587	55.1237	31.4488
ENSG00000108064	homo_sapiens	ENSP00000420588	20.7317	10.5691	ciona_savignyi	ENSCSAVP00000015780	8.31974	4.24144
ENSG00000108064	homo_sapiens	ENSP00000420588	63.0081	36.9919	seriola_lalandi_dorsalis	ENSSLDP00000020385	52.7211	30.9524
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	37.8049	labrus_bergylta	ENSLBEP00000012380	54.2955	31.9588
ENSG00000108064	homo_sapiens	ENSP00000420588	63.8211	39.4309	pundamilia_nyererei	ENSPNYP00000011711	53.7671	33.2192
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	35.7724	mastacembelus_armatus	ENSMAMP00000030573	53.5593	29.8305
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	37.8049	stegastes_partitus	ENSSPAP00000013695	55.4007	32.4042
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	36.9919	acanthochromis_polyacanthus	ENSAPOP00000014728	52.7027	30.7432
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	38.6179	aquila_chrysaetos_chrysaetos	ENSACCP00020005152	58.1132	35.8491
ENSG00000108064	homo_sapiens	ENSP00000420588	60.5691	37.3984	nothobranchius_furzeri	ENSNFUP00015019264	51.9164	32.0557
ENSG00000108064	homo_sapiens	ENSP00000420588	54.065	32.1138	cyprinodon_variegatus	ENSCVAP00000007445	52.5692	31.2253
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	39.8374	denticeps_clupeoides	ENSDCDP00000006418	55	35
ENSG00000108064	homo_sapiens	ENSP00000420588	62.6016	39.8374	denticeps_clupeoides	ENSDCDP00000011463	55	35
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	37.3984	larimichthys_crocea	ENSLCRP00005047475	54.8611	31.9444
ENSG00000108064	homo_sapiens	ENSP00000420588	47.561	29.2683	ficedula_albicollis	ENSFALP00000024072	63.2432	38.9189
ENSG00000108064	homo_sapiens	ENSP00000420588	60.9756	34.9594	hippocampus_comes	ENSHCOP00000015222	52.2648	29.9652
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	39.0244	cyprinus_carpio_carpio	ENSCCRP00000060673	53.4965	33.5664
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	38.6179	cyprinus_carpio_carpio	ENSCCRP00000092344	55.6364	34.5455
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	38.6179	coturnix_japonica	ENSCJPP00005015608	59.0734	36.6795
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	35.3659	poecilia_latipinna	ENSPLAP00000002391	53.3557	29.1946
ENSG00000108064	homo_sapiens	ENSP00000420588	62.1951	38.2114	sinocyclocheilus_grahami	ENSSGRP00000062176	55.6364	34.1818
ENSG00000108064	homo_sapiens	ENSP00000420588	52.0325	29.6748	sinocyclocheilus_grahami	ENSSGRP00000004016	33.5079	19.1099
ENSG00000108064	homo_sapiens	ENSP00000420588	64.2276	39.8374	maylandia_zebra	ENSMZEP00005004110	54.1096	33.5616
ENSG00000108064	homo_sapiens	ENSP00000420588	41.4634	23.9837	tetraodon_nigroviridis	ENSTNIP00000006386	61.4458	35.5422
ENSG00000108064	homo_sapiens	ENSP00000420588	60.5691	37.8049	paramormyrops_kingsleyae	ENSPKIP00000010627	59.3625	37.0518
ENSG00000108064	homo_sapiens	ENSP00000420588	59.7561	37.3984	paramormyrops_kingsleyae	ENSPKIP00000010635	52.5	32.8571
ENSG00000108064	homo_sapiens	ENSP00000420588	60.9756	39.8374	scleropages_formosus	ENSSFOP00015077208	51.3699	33.5616
ENSG00000108064	homo_sapiens	ENSP00000420588	49.187	31.3008	scleropages_formosus	ENSSFOP00015018007	43.3692	27.5986
ENSG00000108064	homo_sapiens	ENSP00000420588	54.065	32.5203	leptobrachium_leishanense	ENSLLEP00000035424	50.1887	30.1887
ENSG00000108064	homo_sapiens	ENSP00000420588	58.9431	37.3984	leptobrachium_leishanense	ENSLLEP00000014944	50.6993	32.1678
ENSG00000108064	homo_sapiens	ENSP00000420588	64.6341	37.3984	scophthalmus_maximus	ENSSMAP00000002317	54.6392	31.6151
ENSG00000108064	homo_sapiens	ENSP00000420588	63.4146	38.2114	oryzias_melastigma	ENSOMEP00000030069	52.8814	31.8644

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000976	enables transcription cis-regulatory region binding	1	IBA	Homo_sapiens(9606)	Function
GO:0001018	enables mitochondrial promoter sequence-specific DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0001223	enables transcription coactivator binding	1	IEA	Homo_sapiens(9606)	Function
GO:0003682	enables chromatin binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	HDA	Homo_sapiens(9606)	Component
GO:0005739	located_in mitochondrion	1	IDA	Homo_sapiens(9606)	Component
GO:0005759	located_in mitochondrial matrix	3	IDA,NAS,TAS	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006390	involved_in mitochondrial transcription	1	IMP	Homo_sapiens(9606)	Process
GO:0006391	involved_in transcription initiation at mitochondrial promoter	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0031072	enables heat shock protein binding	1	IEA	Homo_sapiens(9606)	Function
GO:0032991	part_of protein-containing complex	1	IDA	Homo_sapiens(9606)	Component
GO:0033108	involved_in mitochondrial respiratory chain complex assembly	1	IEA	Homo_sapiens(9606)	Process
GO:0034246	enables mitochondrial transcription factor activity	1	IMP	Homo_sapiens(9606)	Function
GO:0042645	located_in mitochondrial nucleoid	1	IDA	Homo_sapiens(9606)	Component
GO:0043565	enables sequence-specific DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0045893	involved_in positive regulation of DNA-templated transcription	1	IDA	Homo_sapiens(9606)	Process