Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000107201 Gene ID 23586 Accession 19102
Symbol RIGI Alias RIG1;DDX58;RIG-I;RLR-1;SGMRT2 Full Name RNA sensor RIG-I
Status Confidence Length 70907 bases Strand Minus strand
Position 9 : 32455302 - 32526208 RNA binding domain ResIII , DEAD , RIG-I_C , RIG-I_C-RD
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000504921 DEAD PF00270 1.5e-17 1
ENSP00000504921 ResIII PF04851 9.8e-17 2
ENSP00000504921 RIG-I_C-RD PF11648 4.3e-36 3
ENSP00000504921 RIG-I_C PF18119 2.4e-39 4
ENSP00000369197 DEAD PF00270 1.7e-17 1
ENSP00000369197 ResIII PF04851 1.1e-16 2
ENSP00000369197 RIG-I_C-RD PF11648 4.6e-36 3
ENSP00000369197 RIG-I_C PF18119 2.5e-39 4
ENSP00000369213 DEAD PF00270 2e-17 1
ENSP00000369213 ResIII PF04851 1.2e-16 2
ENSP00000369213 RIG-I_C-RD PF11648 5.1e-36 3
ENSP00000369213 RIG-I_C PF18119 2.8e-39 4
ENSP00000505702 RIG-I_C-RD PF11648 2.7e-36 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
17451827 SARS coronavirus and innate immunity. Matthew Frieman 2008-04-01 Virus research
36865165 Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models. L Lily Nguyen 2023-02-23 bioRxiv : the preprint server for biology

Transcripts

Name Transcript ID bp Protein Translation ID
RIGI-204 ENST00000679665 4961 854aa ENSP00000504921
RIGI-202 ENST00000379883 4628 925aa ENSP00000369213
RIGI-201 ENST00000379868 4493 880aa ENSP00000369197
RIGI-205 ENST00000679771 4492 142aa ENSP00000505015
RIGI-209 ENST00000681352 3120 No protein -
RIGI-207 ENST00000680733 3617 76aa ENSP00000504892
RIGI-206 ENST00000679859 2118 425aa ENSP00000505702
RIGI-210 ENST00000681448 4635 No protein -
RIGI-208 ENST00000680883 1282 No protein -
RIGI-203 ENST00000679662 661 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
70278Psoriasis6E-626626624
74184Psoriasis4E-725903422
92431Psoriasis4E-1225574825
100271Psoriasis6E-925574825
102255Menarche2E-626312577
102256Bone Density2E-626312577

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000107201homo_sapiensENSP0000049727144.487829.561homo_sapiensENSP0000036921349.297332.7568
ENSG00000107201homo_sapiensENSP0000025164250.29530.826homo_sapiensENSP0000036921336.864922.5946

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000107201homo_sapiensENSP0000036921358.810857.4054nomascus_leucogenysENSNLEP0000003913993.955191.7098
ENSG00000107201homo_sapiensENSP0000036921399.891999.8919pan_paniscusENSPPAP0000003803899.891999.8919
ENSG00000107201homo_sapiensENSP0000036921399.459598.9189pongo_abeliiENSPPYP0000002145599.459598.9189
ENSG00000107201homo_sapiensENSP00000369213100100pan_troglodytesENSPTRP00000035647100100
ENSG00000107201homo_sapiensENSP0000036921310099.7838gorilla_gorillaENSGGOP0000002416310099.7838
ENSG00000107201homo_sapiensENSP0000036921377.297360.973ornithorhynchus_anatinusENSOANP0000001921476.964560.7104
ENSG00000107201homo_sapiensENSP0000036921355.02745.1892notamacropus_eugeniiENSMEUP0000001023357.644447.3386
ENSG00000107201homo_sapiensENSP0000036921377.297369.4054choloepus_hoffmanniENSCHOP0000000798576.881769.0323
ENSG00000107201homo_sapiensENSP0000036921388.108179.5676dasypus_novemcinctusENSDNOP0000000305587.91879.3959
ENSG00000107201homo_sapiensENSP0000036921370.378461.4054erinaceus_europaeusENSEEUP0000001393270.530961.5385
ENSG00000107201homo_sapiensENSP0000036921397.081194.2703callithrix_jacchusENSCJAP0000001451397.081194.2703
ENSG00000107201homo_sapiensENSP0000036921398.378496.973cercocebus_atysENSCATP0000003468498.378496.973
ENSG00000107201homo_sapiensENSP0000036921397.729795.6757macaca_fascicularisENSMFAP0000005894795.057893.0599
ENSG00000107201homo_sapiensENSP0000036921397.729795.7838macaca_mulattaENSMMUP0000001633897.729795.7838
ENSG00000107201homo_sapiensENSP0000036921397.729795.8919macaca_nemestrinaENSMNEP0000003765397.729795.8919
ENSG00000107201homo_sapiensENSP0000036921397.945996.3243papio_anubisENSPANP0000001916497.945996.3243
ENSG00000107201homo_sapiensENSP0000036921397.729796.1081mandrillus_leucophaeusENSMLEP0000001162197.729796.1081
ENSG00000107201homo_sapiensENSP0000036921373.513566.3784tursiops_truncatusENSTTRP0000001610988.197179.6368
ENSG00000107201homo_sapiensENSP0000036921385.621677.2973vulpes_vulpesENSVVUP0000002892390.514381.7143
ENSG00000107201homo_sapiensENSP0000036921386.378476.5405mus_spretusMGP_SPRETEiJ_P006420986.285176.4579
ENSG00000107201homo_sapiensENSP0000036921391.02782.0541equus_asinusENSEASP0000500619882.468274.3389
ENSG00000107201homo_sapiensENSP0000036921389.081180.1081capra_hircusENSCHIP0000003158987.473578.6624
ENSG00000107201homo_sapiensENSP0000036921389.729780loxodonta_africanaENSLAFP0000000454088.865179.2291
ENSG00000107201homo_sapiensENSP0000036921391.675783.2432panthera_leoENSPLOP0000002625991.280982.8848
ENSG00000107201homo_sapiensENSP0000036921384.864974.9189ailuropoda_melanoleucaENSAMEP0000000402990.126379.5637
ENSG00000107201homo_sapiensENSP0000036921390.270380.6487bos_indicus_hybridENSBIXP0000504347782.104273.353
ENSG00000107201homo_sapiensENSP0000036921387.02776.1081oryctolagus_cuniculusENSOCUP0000001947284.381673.7945
ENSG00000107201homo_sapiensENSP0000036921391.135182.0541equus_caballusENSECAP0000008934682.566174.3389
ENSG00000107201homo_sapiensENSP0000036921391.675783.2432panthera_pardusENSPPRP0000001851791.280982.8848
ENSG00000107201homo_sapiensENSP0000036921388.324379.1351marmota_marmota_marmotaENSMMMP0000000996588.804379.5652
ENSG00000107201homo_sapiensENSP0000036921378.486570.3784balaenoptera_musculusENSBMSP0001000270185.311476.4982
ENSG00000107201homo_sapiensENSP0000036921386.810876.973cavia_porcellusENSCPOP0000000144287.759677.8142
ENSG00000107201homo_sapiensENSP0000036921391.459583.027felis_catusENSFCAP0000000120391.065782.6695
ENSG00000107201homo_sapiensENSP0000036921390.702780.8649ursus_americanusENSUAMP0000002688790.409580.6034
ENSG00000107201homo_sapiensENSP0000036921390.162280.6487bison_bison_bisonENSBBBP0000001405589.773980.3014
ENSG00000107201homo_sapiensENSP0000036921389.189279.5676sus_scrofaENSSSCP0000004526087.579678.1316
ENSG00000107201homo_sapiensENSP0000036921372.97368.8649microcebus_murinusENSMICP0000000600293.490388.2271
ENSG00000107201homo_sapiensENSP0000036921385.405476.4324octodon_degusENSODEP0000002140188.76479.4382
ENSG00000107201homo_sapiensENSP0000036921370.162262.7027jaculus_jaculusENSJJAP0000000260887.940478.5908
ENSG00000107201homo_sapiensENSP0000036921388.648779.7838ovis_aries_rambouilletENSOARP0002001197378.770470.8934
ENSG00000107201homo_sapiensENSP0000036921390.594680.7568ursus_maritimusENSUMAP0000000752090.301780.4957
ENSG00000107201homo_sapiensENSP0000036921361.513552.5405ochotona_princepsENSOPRP0000001535361.580152.5974
ENSG00000107201homo_sapiensENSP0000036921386.270376.6487mus_caroliMGP_CAROLIEiJ_P006177686.177176.5659
ENSG00000107201homo_sapiensENSP0000036921386.810877.0811mus_musculusENSMUSP0000004243386.717176.9978
ENSG00000107201homo_sapiensENSP0000036921389.189277.7297dipodomys_ordiiENSDORP0000002772589.285777.8139
ENSG00000107201homo_sapiensENSP0000036921383.783874.1622mustela_putorius_furoENSMPUP0000000428682.710873.2124
ENSG00000107201homo_sapiensENSP0000036921389.513587.027aotus_nancymaaeENSANAP0000002808396.842194.152
ENSG00000107201homo_sapiensENSP0000036921396.432493.4054saimiri_boliviensis_boliviensisENSSBOP0000002850895.197492.2092
ENSG00000107201homo_sapiensENSP0000036921385.297375.8919vicugna_pacosENSVPAP0000000919588.951579.1432
ENSG00000107201homo_sapiensENSP0000036921398.270396.5405chlorocebus_sabaeusENSCSAP0000000607698.270396.5405
ENSG00000107201homo_sapiensENSP0000036921383.891974.4865mesocricetus_auratusENSMAUP0000002520585.462675.8811
ENSG00000107201homo_sapiensENSP0000036921391.02781.2973camelus_dromedariusENSCDRP0000500936989.289579.7455
ENSG00000107201homo_sapiensENSP0000036921392.324384.973carlito_syrichtaENSTSYP0000000384692.224684.8812
ENSG00000107201homo_sapiensENSP0000036921391.459583.1351panthera_tigris_altaicaENSPTIP0000001663991.065782.7772
ENSG00000107201homo_sapiensENSP0000036921387.459577.5135rattus_norvegicusENSRNOP0000005749287.36577.4298
ENSG00000107201homo_sapiensENSP0000036921392.97386.5946prolemur_simusENSPSMP0000001551392.872686.5011
ENSG00000107201homo_sapiensENSP0000036921373.729765.5135microtus_ochrogasterENSMOCP0000000653388.34278.4974
ENSG00000107201homo_sapiensENSP0000036921373.405463.6757sorex_araneusENSSARP0000000765973.564563.8137
ENSG00000107201homo_sapiensENSP000003692138879.5676peromyscus_maniculatus_bairdiiENSPEMP0000001186787.90579.4816
ENSG00000107201homo_sapiensENSP0000036921390.270380.7568bos_mutusENSBMUP0000002400088.641279.2994
ENSG00000107201homo_sapiensENSP0000036921386.162276.3243mus_spicilegusENSMSIP0000002954286.442576.5727
ENSG00000107201homo_sapiensENSP0000036921387.891979.027cricetulus_griseus_chok1gshdENSCGRP0000102697987.79778.9417
ENSG00000107201homo_sapiensENSP0000036921391.891983.7838pteropus_vampyrusENSPVAP0000000868491.594883.5129
ENSG00000107201homo_sapiensENSP0000036921391.135182.1622myotis_lucifugusENSMLUP0000000276790.840581.8966
ENSG00000107201homo_sapiensENSP0000036921379.567664.8649vombatus_ursinusENSVURP0001000813179.054864.4468
ENSG00000107201homo_sapiensENSP0000036921391.783883.8919rhinolophus_ferrumequinumENSRFEP0001002473291.388683.5307
ENSG00000107201homo_sapiensENSP0000036921390.054180.4324neovison_visonENSNVIP0000000079790.151580.5195
ENSG00000107201homo_sapiensENSP0000036921390.270380.7568bos_taurusENSBTAP0000005351482.104273.4513
ENSG00000107201homo_sapiensENSP0000036921388.648777.9459heterocephalus_glaber_femaleENSHGLP0000002314688.744678.0303
ENSG00000107201homo_sapiensENSP0000036921396.756895.2432rhinopithecus_bietiENSRBIP0000003297597.921296.3895
ENSG00000107201homo_sapiensENSP0000036921390.918981.7297canis_lupus_dingoENSCAFP0002001936588.994780
ENSG00000107201homo_sapiensENSP0000036921389.297381.7297sciurus_vulgarisENSSVLP0000502077989.297381.7297
ENSG00000107201homo_sapiensENSP0000036921380.432465.6216phascolarctos_cinereusENSPCIP0000004005579.914165.1987
ENSG00000107201homo_sapiensENSP0000036921353.405447.1351procavia_capensisENSPCAP0000001507563.252255.8259
ENSG00000107201homo_sapiensENSP0000036921387.783877.8378nannospalax_galiliENSNGAP0000000328887.783877.8378
ENSG00000107201homo_sapiensENSP0000036921390.270380.8649bos_grunniensENSBGRP0000000211588.641279.4055
ENSG00000107201homo_sapiensENSP0000036921383.243272chinchilla_lanigeraENSCLAP000000032778876.1143
ENSG00000107201homo_sapiensENSP0000036921389.189279.8919cervus_hanglu_yarkandensisENSCHYP0000001660887.76678.617
ENSG00000107201homo_sapiensENSP0000036921389.189280catagonus_wagneriENSCWAP0000002390087.953178.8913
ENSG00000107201homo_sapiensENSP0000036921388.108179.1351ictidomys_tridecemlineatusENSSTOP0000000626988.108179.1351
ENSG00000107201homo_sapiensENSP0000036921392.216284.5405otolemur_garnettiiENSOGAP0000000943592.116684.4492
ENSG00000107201homo_sapiensENSP0000036921396.216293.1892cebus_imitatorENSCCAP0000003779196.216293.1892
ENSG00000107201homo_sapiensENSP0000036921384.864976.6487urocitellus_parryiiENSUPAP0001000974988.301579.7525
ENSG00000107201homo_sapiensENSP0000036921390.594681.6216moschus_moschiferusENSMMSP0000002598989.054280.2338
ENSG00000107201homo_sapiensENSP0000036921398.054196.6487rhinopithecus_roxellanaENSRROP0000001020398.054196.6487
ENSG00000107201homo_sapiensENSP0000036921379.891970.3784mus_pahariMGP_PahariEiJ_P005743885.040374.9137
ENSG00000107201homo_sapiensENSP0000036921369.297365.9459propithecus_coquereliENSPCOP0000002889293.168688.6628
ENSG00000107201homo_sapiensENSP0000036921340.216222.3784caenorhabditis_elegansD2005.5.133.24418.4987
ENSG00000107201homo_sapiensENSP0000036921340.324324.3243caenorhabditis_elegansF15B10.2a.135.969121.6972
ENSG00000107201homo_sapiensENSP0000036921315.89198.32432ciona_intestinalisENSCINP0000002385835.853718.7805
ENSG00000107201homo_sapiensENSP0000036921337.189226.3784petromyzon_marinusENSPMAP0000001066259.412842.1416
ENSG00000107201homo_sapiensENSP0000036921342.054127.4595eptatretus_burgeriENSEBUP0000002295253.069634.6521
ENSG00000107201homo_sapiensENSP0000036921365.945948.7568callorhinchus_miliiENSCMIP0000002790764.962748.0298
ENSG00000107201homo_sapiensENSP0000036921367.459549.1892latimeria_chalumnaeENSLACP0000000046166.101748.1992
ENSG00000107201homo_sapiensENSP0000036921365.729748.4324lepisosteus_oculatusENSLOCP0000001655064.680947.6596
ENSG00000107201homo_sapiensENSP0000036921364.432445.4054carassius_auratusENSCARP0000011874047.871533.7349
ENSG00000107201homo_sapiensENSP000003692136444.3243carassius_auratusENSCARP0000002020163.383343.8972
ENSG00000107201homo_sapiensENSP0000036921362.162242.7027carassius_auratusENSCARP0000001865962.432142.8882
ENSG00000107201homo_sapiensENSP0000036921356.540539.7838carassius_auratusENSCARP0000009551566.624246.879
ENSG00000107201homo_sapiensENSP0000036921363.567645.5135astyanax_mexicanusENSAMXP0000001645762.354244.6448
ENSG00000107201homo_sapiensENSP0000036921359.891942.2703ictalurus_punctatusENSIPUP0000000451361.692643.5412
ENSG00000107201homo_sapiensENSP0000036921363.783846.7027esox_luciusENSELUP0000005963060.824744.5361
ENSG00000107201homo_sapiensENSP000003692136445.5135electrophorus_electricusENSEEEP0000003975762.778444.6448
ENSG00000107201homo_sapiensENSP0000036921360.864943.027oncorhynchus_kisutchENSOKIP0000503014459.138741.8067
ENSG00000107201homo_sapiensENSP0000036921363.783845.6216oncorhynchus_mykissENSOMYP0000011540554.42838.9299
ENSG00000107201homo_sapiensENSP000003692136446.4865salmo_salarENSSSAP0000017991860.593744.0123
ENSG00000107201homo_sapiensENSP0000036921364.324346.7027salmo_truttaENSSTUP0000000403460.900744.217
ENSG00000107201homo_sapiensENSP0000036921368.540550.3784xenopus_tropicalisENSXETP0000002020265.563648.1903
ENSG00000107201homo_sapiensENSP0000036921371.459555.5676chrysemys_picta_belliiENSCPBP0000001058662.535548.6282
ENSG00000107201homo_sapiensENSP000003692137256.2162sphenodon_punctatusENSSPUP0000000376972.628156.7067
ENSG00000107201homo_sapiensENSP000003692137255.2432crocodylus_porosusENSCPRP0000502213171.767255.0647
ENSG00000107201homo_sapiensENSP0000036921367.891951.6757laticauda_laticaudataENSLLTP0000002291069.01152.5275
ENSG00000107201homo_sapiensENSP0000036921363.675748.8649notechis_scutatusENSNSUP0000000982365.883750.5593
ENSG00000107201homo_sapiensENSP0000036921366.594651.027pseudonaja_textilisENSPTXP0000002199466.236650.7527
ENSG00000107201homo_sapiensENSP0000036921365.081148.6486anas_platyrhynchos_platyrhynchosENSAPLP0000001496968.409151.1364
ENSG00000107201homo_sapiensENSP0000036921370.054153.1892serinus_canariaENSSCAP0000001774870.054153.1892
ENSG00000107201homo_sapiensENSP0000036921371.459553.4054parus_majorENSPMJP0000000489464.424948.1481
ENSG00000107201homo_sapiensENSP0000036921358.702743.7838anolis_carolinensisENSACAP0000004031168.647351.201
ENSG00000107201homo_sapiensENSP0000036921365.945950.4865naja_najaENSNNAP0000001650070.114953.6782
ENSG00000107201homo_sapiensENSP0000036921371.459556.1081podarcis_muralisENSPMRP0000003304571.69256.2907
ENSG00000107201homo_sapiensENSP0000036921365.513549.7297geospiza_fortisENSGFOP0000001334169.495452.7523
ENSG00000107201homo_sapiensENSP0000036921370.162252.4324taeniopygia_guttataENSTGUP0000000156767.745350.6263
ENSG00000107201homo_sapiensENSP0000036921370.378454.4865salvator_merianaeENSSMRP0000002710370.226554.3689
ENSG00000107201homo_sapiensENSP0000036921372.540556.3243pelodiscus_sinensisENSPSIP0000001548772.30656.1422
ENSG00000107201homo_sapiensENSP0000036921372.108156.3243gopherus_evgoodeiENSGEVP0000501524171.643455.9613
ENSG00000107201homo_sapiensENSP0000036921372.216256.3243chelonoidis_abingdoniiENSCABP0000000454571.750855.9613
ENSG00000107201homo_sapiensENSP0000036921369.837852.1081struthio_camelus_australisENSSCUP0000002154269.913452.1645
ENSG00000107201homo_sapiensENSP0000036921371.351353.2973anser_brachyrhynchusENSABRP0000000913570.815552.897
ENSG00000107201homo_sapiensENSP0000036921371.243253.7297strigops_habroptilaENSSHBP0000502313471.012953.556
ENSG00000107201homo_sapiensENSP0000036921370.594654.5946terrapene_carolina_triunguisENSTMTP0000002699870.442354.4768
ENSG00000107201homo_sapiensENSP0000036921368.648753.6216terrapene_carolina_triunguisENSTMTP0000001709872.821156.8807
ENSG00000107201homo_sapiensENSP000003692139.621626.91892hucho_huchoENSHHUP0000007417651.445136.9942
ENSG00000107201homo_sapiensENSP0000036921330.054121.0811hucho_huchoENSHHUP0000003064760.434842.3913
ENSG00000107201homo_sapiensENSP0000036921363.459544.8649pygocentrus_nattereriENSPNAP0000000640861.209643.2742
ENSG00000107201homo_sapiensENSP000003692137.027034.21622ciona_savignyiENSCSAVP0000001892333.678820.2073
ENSG00000107201homo_sapiensENSP000003692134.756762.81081saccharomyces_cerevisiaeYHR218W-A41.904824.7619
ENSG00000107201homo_sapiensENSP0000036921327.135113.5135saccharomyces_cerevisiaeYOR396W13.97556.95991
ENSG00000107201homo_sapiensENSP000003692139.837845.18919saccharomyces_cerevisiaeYHL050C13.0566.88666
ENSG00000107201homo_sapiensENSP0000036921315.45958.75676saccharomyces_cerevisiaeYPR204W13.85667.84884
ENSG00000107201homo_sapiensENSP0000036921319.891910.5946saccharomyces_cerevisiaeYLL066C15.26978.13278
ENSG00000107201homo_sapiensENSP0000036921314.05416.37838saccharomyces_cerevisiaeYHR218W21.55899.78441
ENSG00000107201homo_sapiensENSP0000036921327.02713.4054saccharomyces_cerevisiaeYJL225C14.22077.05347
ENSG00000107201homo_sapiensENSP0000036921329.405414.4865saccharomyces_cerevisiaeYNL339C14.63157.20818
ENSG00000107201homo_sapiensENSP0000036921327.135113.5135saccharomyces_cerevisiaeYLR467W13.97556.95991
ENSG00000107201homo_sapiensENSP000003692135.513513.35135saccharomyces_cerevisiaeYBL113C6.439393.91414
ENSG00000107201homo_sapiensENSP0000036921327.135113.5135saccharomyces_cerevisiaeYDR545W13.97556.95991
ENSG00000107201homo_sapiensENSP0000036921327.02713.4054saccharomyces_cerevisiaeYIL177C14.22077.05347
ENSG00000107201homo_sapiensENSP000003692137.027033.13514saccharomyces_cerevisiaeYPR202W27.310912.1849
ENSG00000107201homo_sapiensENSP0000036921310.48655.72973saccharomyces_cerevisiaeYFL066C24.744913.5204
ENSG00000107201homo_sapiensENSP000003692133.351351.51351saccharomyces_cerevisiaeYEL075C25.409811.4754
ENSG00000107201homo_sapiensENSP0000036921319.351410.1622saccharomyces_cerevisiaeYEL077C14.01727.361
ENSG00000107201homo_sapiensENSP0000036921323.675712.1081saccharomyces_cerevisiaeYER190W13.0286.6627
ENSG00000107201homo_sapiensENSP000003692135.513512.48649saccharomyces_cerevisiaeYLR462W25.247511.3861
ENSG00000107201homo_sapiensENSP000003692134.756762.81081saccharomyces_cerevisiaeYBL112C41.904824.7619
ENSG00000107201homo_sapiensENSP0000036921329.405414.4865saccharomyces_cerevisiaeYPL283C14.63157.20818
ENSG00000107201homo_sapiensENSP000003692136.70273.13514saccharomyces_cerevisiaeYHL049C22.878210.7011
ENSG00000107201homo_sapiensENSP0000036921324.864912.8649saccharomyces_cerevisiaeYML133C16.73948.66084
ENSG00000107201homo_sapiensENSP000003692135.405413.35135saccharomyces_cerevisiaeYHR219W8.012824.96795
ENSG00000107201homo_sapiensENSP0000036921329.405414.4865saccharomyces_cerevisiaeYGR296W14.63157.20818
ENSG00000107201homo_sapiensENSP0000036921319.891910.5946saccharomyces_cerevisiaeYLL067C15.26978.13278
ENSG00000107201homo_sapiensENSP0000036921320.108110.4865saccharomyces_cerevisiaeYLR466W13.45887.01881
ENSG00000107201homo_sapiensENSP000003692133.351351.51351saccharomyces_cerevisiaeYER189W25.409811.4754
ENSG00000107201homo_sapiensENSP0000036921315.89197.35135saccharomyces_cerevisiaeYBL111C22.03910.1949
ENSG00000107201homo_sapiensENSP000003692134.756762.27027saccharomyces_cerevisiaeYFL064C25.287412.069
ENSG00000107201homo_sapiensENSP0000036921372.324354.9189aquila_chrysaetos_chrysaetosENSACCP0002001909868.89852.3172
ENSG00000107201homo_sapiensENSP0000036921365.405450.2703ficedula_albicollisENSFALP0000000120870.595154.259
ENSG00000107201homo_sapiensENSP0000036921365.081145.5135cyprinus_carpio_carpioENSCCRP0000014873363.636444.5032
ENSG00000107201homo_sapiensENSP0000036921335.02723.6757sinocyclocheilus_grahamiENSSGRP0000003827458.064539.2473
ENSG00000107201homo_sapiensENSP0000036921364.97347.2432paramormyrops_kingsleyaeENSPKIP0000004006065.255247.4484
ENSG00000107201homo_sapiensENSP0000036921363.675747.027scleropages_formosusENSSFOP0001502705662.927346.4744
ENSG00000107201homo_sapiensENSP0000036921366.594650.0541leptobrachium_leishanenseENSLLEP0000000348664.367848.3804
ENSG00000107201homo_sapiensENSP0000036921366.486549.8378leptobrachium_leishanenseENSLLEP0000001696364.736848.5263

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0002230involved_in positive regulation of defense response to virus by host1IMPHomo_sapiens(9606)Process
GO:0002735involved_in positive regulation of myeloid dendritic cell cytokine production1ISSHomo_sapiens(9606)Process
GO:0002753involved_in cytosolic pattern recognition receptor signaling pathway2IDA,TASHomo_sapiens(9606)Process
GO:0003690enables double-stranded DNA binding1IEAHomo_sapiens(9606)Function
GO:0003724enables RNA helicase activity1IMPHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding4IBA,IDA,IMP,TASHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding2IBA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005525enables GTP binding1IMPHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm3IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005923located_in bicellular tight junction1IDAHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding2IBA,IDAHomo_sapiens(9606)Function
GO:0009597involved_in detection of virus1IDAHomo_sapiens(9606)Process
GO:0009615involved_in response to virus1TASHomo_sapiens(9606)Process
GO:0010467involved_in gene expression1IEAHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0015629located_in actin cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity1IMPHomo_sapiens(9606)Function
GO:0030334involved_in regulation of cell migration1IDAHomo_sapiens(9606)Process
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0032587located_in ruffle membrane1IDAHomo_sapiens(9606)Component
GO:0032725involved_in positive regulation of granulocyte macrophage colony-stimulating factor production1IDAHomo_sapiens(9606)Process
GO:0032727involved_in positive regulation of interferon-alpha production2IDA,IMPHomo_sapiens(9606)Process
GO:0032728involved_in positive regulation of interferon-beta production2IDA,IMPHomo_sapiens(9606)Process
GO:0032755involved_in positive regulation of interleukin-6 production2IDA,IMPHomo_sapiens(9606)Process
GO:0032757involved_in positive regulation of interleukin-8 production1IDAHomo_sapiens(9606)Process
GO:0032760involved_in positive regulation of tumor necrosis factor production1IMPHomo_sapiens(9606)Process
GO:0034344involved_in regulation of type III interferon production1TASHomo_sapiens(9606)Process
GO:0038187enables pattern recognition receptor activity1IDAHomo_sapiens(9606)Function
GO:0039529involved_in RIG-I signaling pathway2IDA,IMPHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043330acts_upstream_of_or_within response to exogenous dsRNA1ISSHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IMPHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0051091involved_in positive regulation of DNA-binding transcription factor activity1IDAHomo_sapiens(9606)Process
GO:0051607involved_in defense response to virus1IDAHomo_sapiens(9606)Process
GO:0060760involved_in positive regulation of response to cytokine stimulus1IMPHomo_sapiens(9606)Process
GO:0071360involved_in cellular response to exogenous dsRNA1IMPHomo_sapiens(9606)Process
GO:0140374involved_in antiviral innate immune response2IBA,IDAHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression