Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs snRNA
Moonlighting functions N.A.
Localizations P-bodyNucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000106344 Gene ID 55131 Accession 21863
Symbol RBM28 Alias ANES;NOP4 Full Name RNA binding motif protein 28
Status Confidence Length 46224 bases Strand Minus strand
Position 7 : 128297685 - 128343908 RNA binding domain RRM_1
Summary The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Phenotypes

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression