Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000105298 Gene ID 58509 Accession 29938
Symbol CACTIN Alias Full Name
Status Confidence Length 16171 bases Strand Minus strand
Position 19 : 3610645 - 3626815 RNA binding domain N.A.
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
CACTIN-208 ENST00000591726 699 117aa ENSP00000464898
CACTIN-210 ENST00000592721 1220 291aa ENSP00000467149
CACTIN-203 ENST00000429344 3583 758aa ENSP00000415078
CACTIN-204 ENST00000585942 2810 758aa ENSP00000465751
CACTIN-202 ENST00000248420 2671 758aa ENSP00000248420
CACTIN-201 ENST00000221899 2797 758aa ENSP00000221899
CACTIN-207 ENST00000589321 1708 141aa ENSP00000466600
CACTIN-205 ENST00000587175 2216 No protein -
CACTIN-206 ENST00000588749 391 130aa ENSP00000467788
CACTIN-209 ENST00000591978 2283 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
70495Insulin-Like Growth Factor Binding Protein 36E-623251661

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000105298homo_sapiensENSP0000026848530.673317.9551homo_sapiensENSP0000041507816.22699.49868
ENSG00000105298homo_sapiensENSP0000039175930.56617.3585homo_sapiensENSP0000041507810.6866.0686

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000105298homo_sapiensENSP0000041507873.350972.2955nomascus_leucogenysENSNLEP0000000309688.9687.68
ENSG00000105298homo_sapiensENSP0000041507893.535693.2718pan_paniscusENSPPAP0000000994899.859299.5775
ENSG00000105298homo_sapiensENSP0000041507899.340498.8127pongo_abeliiENSPPYP0000001052399.078998.5526
ENSG00000105298homo_sapiensENSP0000041507899.472399.2084pan_troglodytesENSPTRP0000001745899.735599.4709
ENSG00000105298homo_sapiensENSP0000041507899.868199.4723gorilla_gorillaENSGGOP0000001222199.736599.3412
ENSG00000105298homo_sapiensENSP0000041507887.46782.058dasypus_novemcinctusENSDNOP0000002851988.164982.7128
ENSG00000105298homo_sapiensENSP0000041507843.931442.2164echinops_telfairiENSETEP0000000100952.689950.6329
ENSG00000105298homo_sapiensENSP0000041507898.416997.3615callithrix_jacchusENSCJAP0000002751597.516396.4706
ENSG00000105298homo_sapiensENSP0000041507898.416997.8892cercocebus_atysENSCATP0000003939398.157997.6316
ENSG00000105298homo_sapiensENSP0000041507898.680797.8892macaca_mulattaENSMMUP0000003197198.421197.6316
ENSG00000105298homo_sapiensENSP0000041507893.403792.3483macaca_nemestrinaENSMNEP0000002957095.033693.9597
ENSG00000105298homo_sapiensENSP0000041507898.680798.0211papio_anubisENSPANP0000002835498.421197.7632
ENSG00000105298homo_sapiensENSP0000041507892.744191.5567mandrillus_leucophaeusENSMLEP0000000393894.871893.6572
ENSG00000105298homo_sapiensENSP0000041507877.044975.7256tursiops_truncatusENSTTRP0000000545278.284276.9437
ENSG00000105298homo_sapiensENSP0000041507894.459192.6121vulpes_vulpesENSVVUP0000000427295.212893.3511
ENSG00000105298homo_sapiensENSP0000041507891.424886.6755mus_spretusMGP_SPRETEiJ_P002528890.11785.4356
ENSG00000105298homo_sapiensENSP0000041507894.72391.9525equus_asinusENSEASP0000505309095.351992.5631
ENSG00000105298homo_sapiensENSP0000041507889.31487.467capra_hircusENSCHIP0000003303195.621593.6441
ENSG00000105298homo_sapiensENSP0000041507821.899720.9763loxodonta_africanaENSLAFP0000002458792.737488.8268
ENSG00000105298homo_sapiensENSP0000041507893.667591.029panthera_leoENSPLOP0000002433794.289591.6335
ENSG00000105298homo_sapiensENSP0000041507890.765289.0501ailuropoda_melanoleucaENSAMEP0000004060789.119287.4352
ENSG00000105298homo_sapiensENSP0000041507894.327292.3483bos_indicus_hybridENSBIXP0000503417194.576792.5926
ENSG00000105298homo_sapiensENSP0000041507894.854991.9525equus_caballusENSECAP0000003844595.484792.5631
ENSG00000105298homo_sapiensENSP0000041507894.459192.6121canis_lupus_familiarisENSCAFP0084501210995.212893.3511
ENSG00000105298homo_sapiensENSP0000041507879.947277.3087panthera_pardusENSPPRP0000001395093.374490.2928
ENSG00000105298homo_sapiensENSP0000041507887.730985.0923marmota_marmota_marmotaENSMMMP0000001902692.23389.4591
ENSG00000105298homo_sapiensENSP0000041507893.931490.7652balaenoptera_musculusENSBMSP0001001122594.304691.1258
ENSG00000105298homo_sapiensENSP0000041507893.271890.6332cavia_porcellusENSCPOP0000000350293.642490.9934
ENSG00000105298homo_sapiensENSP0000041507893.667591.2929felis_catusENSFCAP0000002152894.164591.7772
ENSG00000105298homo_sapiensENSP0000041507894.72392.876ursus_americanusENSUAMP0000002186895.478793.617
ENSG00000105298homo_sapiensENSP0000041507894.59192.4802bison_bison_bisonENSBBBP0000002706795.219193.0943
ENSG00000105298homo_sapiensENSP0000041507894.327291.029monodon_monocerosENSMMNP0001500101794.70291.3907
ENSG00000105298homo_sapiensENSP0000041507895.118792.0844sus_scrofaENSSSCP0000005634795.623392.5729
ENSG00000105298homo_sapiensENSP0000041507894.72393.1398microcebus_murinusENSMICP0000000756095.351993.7583
ENSG00000105298homo_sapiensENSP0000041507882.849678.1003octodon_degusENSODEP0000002089586.501481.5427
ENSG00000105298homo_sapiensENSP0000041507894.72391.9525octodon_degusENSODEP0000001996294.973592.1958
ENSG00000105298homo_sapiensENSP0000041507891.556787.5989jaculus_jaculusENSJJAP0000002030192.780788.7701
ENSG00000105298homo_sapiensENSP0000041507894.854992.7441ovis_aries_rambouilletENSOARP0002002386395.105892.9894
ENSG00000105298homo_sapiensENSP0000041507813.588411.0818ursus_maritimusENSUMAP0000000977054.497444.4444
ENSG00000105298homo_sapiensENSP0000041507894.195390.7652delphinapterus_leucasENSDLEP0000002119594.569591.1258
ENSG00000105298homo_sapiensENSP0000041507893.535690.6332physeter_catodonENSPCTP0000502595294.156791.2351
ENSG00000105298homo_sapiensENSP0000041507812.269110.8179mus_caroliMGP_CAROLIEiJ_P008485271.538563.0769
ENSG00000105298homo_sapiensENSP0000041507891.820687.2032mus_caroliMGP_CAROLIEiJ_P002411491.099586.5183
ENSG00000105298homo_sapiensENSP0000041507891.556786.8074mus_musculusENSMUSP0000005953389.896485.2332
ENSG00000105298homo_sapiensENSP0000041507854.221652.7704dipodomys_ordiiENSDORP0000000382591.946389.4855
ENSG00000105298homo_sapiensENSP0000041507894.59192.0844mustela_putorius_furoENSMPUP0000000400295.345792.8191
ENSG00000105298homo_sapiensENSP0000041507898.28596.8338aotus_nancymaaeENSANAP0000003409394.184692.7939
ENSG00000105298homo_sapiensENSP0000041507876.385275.066saimiri_boliviensis_boliviensisENSSBOP0000003586498.302296.6044
ENSG00000105298homo_sapiensENSP0000041507842.480240.5013vicugna_pacosENSVPAP0000000329646.870544.687
ENSG00000105298homo_sapiensENSP0000041507889.577889.1821chlorocebus_sabaeusENSCSAP0000000732998.691998.2558
ENSG00000105298homo_sapiensENSP0000041507889.709885.3562mesocricetus_auratusENSMAUP0000001092285.106480.9762
ENSG00000105298homo_sapiensENSP0000041507894.327290.7652phocoena_sinusENSPSNP0000002635394.70291.1258
ENSG00000105298homo_sapiensENSP0000041507895.118793.0079camelus_dromedariusENSCDRP0000500835395.877793.75
ENSG00000105298homo_sapiensENSP0000041507890.501386.2797rattus_norvegicusENSRNOP0000002792689.790685.6021
ENSG00000105298homo_sapiensENSP0000041507894.72393.0079prolemur_simusENSPSMP0000002736395.099393.3775
ENSG00000105298homo_sapiensENSP0000041507891.02987.3351microtus_ochrogasterENSMOCP0000001174592.493388.7399
ENSG00000105298homo_sapiensENSP0000041507849.208441.8206sorex_araneusENSSARP0000000833573.5762.5247
ENSG00000105298homo_sapiensENSP0000041507885.092381.5303peromyscus_maniculatus_bairdiiENSPEMP0000002525094.298290.3509
ENSG00000105298homo_sapiensENSP0000041507894.459192.3483bos_mutusENSBMUP0000002412194.70992.5926
ENSG00000105298homo_sapiensENSP0000041507891.424886.6755mus_spicilegusENSMSIP000000286249085.3247
ENSG00000105298homo_sapiensENSP0000041507891.820687.8628cricetulus_griseus_chok1gshdENSCGRP0000102288892.553288.5638
ENSG00000105298homo_sapiensENSP0000041507885.356283.905pteropus_vampyrusENSPVAP0000000407577.951876.6265
ENSG00000105298homo_sapiensENSP0000041507892.744190.3694myotis_lucifugusENSMLUP0000000321492.989490.6085
ENSG00000105298homo_sapiensENSP0000041507893.271890.8971rhinolophus_ferrumequinumENSRFEP0001003102793.766691.3793
ENSG00000105298homo_sapiensENSP0000041507894.59192.3483neovison_visonENSNVIP0000000830995.345793.0851
ENSG00000105298homo_sapiensENSP0000041507894.327292.2164bos_taurusENSBTAP0000001369794.576792.4603
ENSG00000105298homo_sapiensENSP0000041507893.007991.1609heterocephalus_glaber_femaleENSHGLP0000004351989.353687.5792
ENSG00000105298homo_sapiensENSP0000041507899.076598.4169rhinopithecus_bietiENSRBIP0000000148693.40892.7861
ENSG00000105298homo_sapiensENSP0000041507894.327292.4802canis_lupus_dingoENSCAFP0002002320195.079893.2181
ENSG00000105298homo_sapiensENSP0000041507894.854992.876sciurus_vulgarisENSSVLP0000503020795.484793.4927
ENSG00000105298homo_sapiensENSP0000041507879.287677.1768procavia_capensisENSPCAP0000001037675.12573.125
ENSG00000105298homo_sapiensENSP0000041507890.501386.5435nannospalax_galiliENSNGAP0000002157390.144586.2024
ENSG00000105298homo_sapiensENSP0000041507894.459192.3483bos_grunniensENSBGRP0000003335094.70992.5926
ENSG00000105298homo_sapiensENSP0000041507892.744190.5013chinchilla_lanigeraENSCLAP0000001558692.989490.7407
ENSG00000105298homo_sapiensENSP0000041507894.59192.7441cervus_hanglu_yarkandensisENSCHYP0000000555691.805490.0128
ENSG00000105298homo_sapiensENSP0000041507894.986891.8206catagonus_wagneriENSCWAP0000001413495.490792.3077
ENSG00000105298homo_sapiensENSP0000041507891.02989.0501ictidomys_tridecemlineatusENSSTOP0000000111095.833393.75
ENSG00000105298homo_sapiensENSP0000041507885.75284.4327otolemur_garnettiiENSOGAP0000000929796.011894.5347
ENSG00000105298homo_sapiensENSP0000041507898.680797.3615cebus_imitatorENSCCAP0000002179898.291796.9777
ENSG00000105298homo_sapiensENSP0000041507893.931491.9525urocitellus_parryiiENSUPAP0001001055194.806992.8096
ENSG00000105298homo_sapiensENSP0000041507894.063392.0844moschus_moschiferusENSMMSP0000003106794.813892.8191
ENSG00000105298homo_sapiensENSP0000041507891.820690.7652rhinopithecus_roxellanaENSRROP0000001650696.132695.0276
ENSG00000105298homo_sapiensENSP0000041507891.292986.4116mus_pahariMGP_PahariEiJ_P008726392.021387.1011
ENSG00000105298homo_sapiensENSP0000041507894.986893.2718propithecus_coquereliENSPCOP0000000925695.238193.5185

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000398involved_in mRNA splicing, via spliceosome2IC,IMPHomo_sapiens(9606)Process
GO:0001933involved_in negative regulation of protein phosphorylation1IMPHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005681part_of spliceosomal complex1IBAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0031665involved_in negative regulation of lipopolysaccharide-mediated signaling pathway1IMPHomo_sapiens(9606)Process
GO:0032088involved_in negative regulation of NF-kappaB transcription factor activity1IDAHomo_sapiens(9606)Process
GO:0032688involved_in negative regulation of interferon-beta production1IMPHomo_sapiens(9606)Process
GO:0032717involved_in negative regulation of interleukin-8 production1IDAHomo_sapiens(9606)Process
GO:0032720involved_in negative regulation of tumor necrosis factor production1IDAHomo_sapiens(9606)Process
GO:0034122involved_in negative regulation of toll-like receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0043124involved_in negative regulation of I-kappaB kinase/NF-kappaB signaling1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045292involved_in mRNA cis splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0045824involved_in negative regulation of innate immune response1IBAHomo_sapiens(9606)Process
GO:0060339involved_in negative regulation of type I interferon-mediated signaling pathway1IMPHomo_sapiens(9606)Process
GO:0071013part_of catalytic step 2 spliceosome1IDAHomo_sapiens(9606)Component
GO:0071222involved_in cellular response to lipopolysaccharide1IDAHomo_sapiens(9606)Process
GO:0071347involved_in cellular response to interleukin-11IDAHomo_sapiens(9606)Process
GO:0071356involved_in cellular response to tumor necrosis factor1IDAHomo_sapiens(9606)Process

Expression