RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	snoRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000104872	Gene ID	55011	Accession	26075
Symbol	PIH1D1	Alias	Pih1;MOT48;NOP17;DNAAF14	Full Name	PIH1 domain containing 1
Status	Confidence	Length	7200 bases	Strand	Minus strand
Position	19 : 49446298 - 49453497	RNA binding domain	PIH1
Summary	Enables several functions, including RNA polymerase I core promoter sequence-specific DNA binding activity; enzyme binding activity; and phosphoprotein binding activity. Involved in several processes, including box C/D snoRNP assembly; positive regulation of signal transduction; and regulation of cellular protein metabolic process. Located in cytoplasm and nucleolus. Part of R2TP complex and pre-snoRNP complex. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000469693	PIH1	PF08190	1.7e-35	1
ENSP00000262265	PIH1	PF08190	1.9e-35	1
ENSP00000470445	PIH1	PF08190	1.9e-35	1
ENSP00000469793	PIH1	PF08190	2.5e-33	1
ENSP00000469087	PIH1	PF08190	4.7e-31	1
ENSP00000469087	PIH1	PF08190	4.7e-31	2
ENSP00000470639	PIH1	PF08190	1.3e-23	1
ENSP00000473095	PIH1	PF08190	1.1e-19	1
ENSP00000473100	PIH1	PF08190	1.8e-17	1
ENSP00000472065	PIH1	PF08190	1.8e-16	1
ENSP00000470947	PIH1	PF08190	6.3e-14	1
ENSP00000471275	PIH1	PF08190	1.6e-10	1
ENSP00000472715	PIH1	PF08190	2.7e-09	1
ENSP00000470322	PIH1	PF08190	4.5e-08	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
PIH1D1-208	ENST00000595633	424	No protein	-
PIH1D1-212	ENST00000596916	793	95aa	ENSP00000472065
PIH1D1-201	ENST00000262265	1197	290aa	ENSP00000262265
PIH1D1-223	ENST00000602076	474	No protein	-
PIH1D1-224	ENST00000602226	341	No protein	-
PIH1D1-215	ENST00000598175	418	55aa	ENSP00000470875
PIH1D1-214	ENST00000597577	698	114aa	ENSP00000472715
PIH1D1-204	ENST00000594845	489	54aa	ENSP00000470322
PIH1D1-202	ENST00000593629	1084	No protein	-
PIH1D1-216	ENST00000598889	615	87aa	ENSP00000470947
PIH1D1-219	ENST00000600875	633	183aa	ENSP00000473095
PIH1D1-210	ENST00000596651	741	129aa	ENSP00000470639
PIH1D1-209	ENST00000596049	992	290aa	ENSP00000470445
PIH1D1-221	ENST00000601807	998	273aa	ENSP00000469693
PIH1D1-220	ENST00000601053	634	115aa	ENSP00000473100
PIH1D1-211	ENST00000596895	438	No protein	-
PIH1D1-206	ENST00000595516	841	No protein	-
PIH1D1-217	ENST00000599366	833	236aa	ENSP00000469087
PIH1D1-213	ENST00000597415	874	164aa	ENSP00000469793
PIH1D1-203	ENST00000593900	932	No protein	-
PIH1D1-205	ENST00000595074	1037	No protein	-
PIH1D1-218	ENST00000599791	966	No protein	-
PIH1D1-222	ENST00000601825	381	82aa	ENSP00000471275
PIH1D1-207	ENST00000595550	583	35aa	ENSP00000472571

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000492	involved_in box C/D snoRNP assembly	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0001165	NOT enables RNA polymerase I cis-regulatory region sequence-specific DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0006338	involved_in chromatin remodeling	1	IMP	Homo_sapiens(9606)	Process
GO:0006364	involved_in rRNA processing	1	IBA	Homo_sapiens(9606)	Process
GO:0019901	enables protein kinase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0030855	involved_in epithelial cell differentiation	1	IEP	Homo_sapiens(9606)	Process
GO:0042393	enables histone binding	1	IPI	Homo_sapiens(9606)	Function
GO:0048254	involved_in snoRNA localization	1	IMP	Homo_sapiens(9606)	Process
GO:0050821	involved_in protein stabilization	1	NAS	Homo_sapiens(9606)	Process
GO:0051117	enables ATPase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0051219	enables phosphoprotein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0070761	part_of pre-snoRNP complex	1	IDA	Homo_sapiens(9606)	Component
GO:0071902	involved_in positive regulation of protein serine/threonine kinase activity	1	IMP	Homo_sapiens(9606)	Process
GO:0097255	part_of R2TP complex	3	IBA,IDA,IPI	Homo_sapiens(9606)	Component
GO:0140566	enables histone reader activity	1	IMP	Homo_sapiens(9606)	Function
GO:1901838	involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	2	IGI,IMP	Homo_sapiens(9606)	Process
GO:1902661	involved_in positive regulation of glucose mediated signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:1903939	NOT involved_in regulation of TORC2 signaling	1	IMP	Homo_sapiens(9606)	Process
GO:1904263	involved_in positive regulation of TORC1 signaling	1	IMP	Homo_sapiens(9606)	Process
GO:1905669	involved_in TORC1 complex assembly	1	IDA	Homo_sapiens(9606)	Process
GO:1990062	part_of RPAP3/R2TP/prefoldin-like complex	1	IPI	Homo_sapiens(9606)	Component
GO:1990904	part_of ribonucleoprotein complex	1	IBA	Homo_sapiens(9606)	Component
GO:2001268	involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1	IMP	Homo_sapiens(9606)	Process