Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000104691 Gene ID 7993 Accession 30307
Symbol UBXN8 Alias REP8;UBXD6;D8S2298E Full Name UBX domain protein 8
Status Confidence Length 37876 bases Strand Plus strand
Position 8 : 30729131 - 30767006 RNA binding domain RNase_H
Summary p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2013]

RNA binding domains (RBDs)

Transcripts

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression