Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000104517 Gene ID 51366 Accession 16806
Symbol UBR5 Alias DD5;EDD;HYD;EDD1 Full Name ubiquitin protein ligase E3 component n-recognin 5
Status Confidence Length 160487 bases Strand Minus strand
Position 8 : 102252273 - 102412759 RNA binding domain PABP
Summary This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000428693 PABP PF00658 2.3e-21 1
ENSP00000220959 PABP PF00658 1.7e-20 1
ENSP00000429084 PABP PF00658 1.7e-20 1
ENSP00000427819 PABP PF00658 1.7e-20 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35727840 A MademoiseLLE domain binding platform links the key RNA transporter to endosomes. Senthil-Kumar Devan 2022-06-01 PLoS genetics
33649862 Emerging roles of circular RNAs in non‑small cell lung cancer (Review). Shanshan Li 2021-04-01 Oncology reports
34849774 Genome-wide analysis of acute low salinity tolerance in the eastern oyster Crassostrea virginica and potential of genomic selection for trait improvement. J Alexandra McCarty 2022-01-04 G3 (Bethesda, Md.)
30038412 The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Seda Koyuncu 2018-07-23 Nature communications
37409633 Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5. Zuzana Hodáková 2023-08-15 The EMBO journal

Transcripts

Name Transcript ID bp Protein Translation ID
UBR5-207 ENST00000520539 10895 2799aa ENSP00000429084
UBR5-201 ENST00000220959 9418 2798aa ENSP00000220959
UBR5-202 ENST00000517465 1095 No protein -
UBR5-204 ENST00000518205 1931 527aa ENSP00000428693
UBR5-212 ENST00000521922 9008 2792aa ENSP00000427819
UBR5-211 ENST00000521767 1763 No protein -
UBR5-209 ENST00000521312 560 No protein -
UBR5-210 ENST00000521566 563 166aa ENSP00000428062
UBR5-206 ENST00000519528 325 No protein -
UBR5-208 ENST00000520898 582 194aa ENSP00000429127
UBR5-205 ENST00000519365 602 201aa ENSP00000428138
UBR5-203 ENST00000518145 598 No protein -
UBR5-213 ENST00000522327 701 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
5353Cholesterol, LDL4.06432921751035E-1117903299
21033Personality Inventory5.105e-005-
21077Personality Inventory3.884e-005-
55346Myoglobin1.2600000E-005-
78791Gestational Age4E-627490719
78792Live Birth4E-627490719
92353Diabetes Mellitus, Type 22E-628060188

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000104517homo_sapiensENSP0000034059630.711615.824homo_sapiensENSP0000042908411.71856.03787
ENSG00000104517homo_sapiensENSP0000036280426.120113.346homo_sapiensENSP000004290849.789215.00179
ENSG00000104517homo_sapiensENSP0000038568428.095214.6667homo_sapiensENSP0000042908410.53955.50197
ENSG00000104517homo_sapiensENSP0000049541827.671815.3308homo_sapiensENSP0000042908415.54138.61022
ENSG00000104517homo_sapiensENSP0000036399847.099827.6102homo_sapiensENSP0000042908414.50528.50304
ENSG00000104517homo_sapiensENSP0000035532643.638924.8974homo_sapiensENSP0000042908411.39696.50232
ENSG00000104517homo_sapiensENSP0000050271319.883910.1113homo_sapiensENSP0000042908414.68387.46695
ENSG00000104517homo_sapiensENSP0000026434629.060714.2857homo_sapiensENSP0000042908410.61095.21615
ENSG00000104517homo_sapiensENSP0000029806836.597918.299homo_sapiensENSP0000042908410.14655.07324
ENSG00000104517homo_sapiensENSP000002616099.267694.6959homo_sapiensENSP0000042908416.00578.11004
ENSG00000104517homo_sapiensENSP0000037922827.646315.6912homo_sapiensENSP0000042908415.86289.00322
ENSG00000104517homo_sapiensENSP0000034871432.320816.7679homo_sapiensENSP000004290849.503394.93033
ENSG00000104517homo_sapiensENSP0000041061342.777824.4444homo_sapiensENSP0000042908413.75497.85995
ENSG00000104517homo_sapiensENSP0000030919835.734117.4515homo_sapiensENSP0000042908413.82646.75241
ENSG00000104517homo_sapiensENSP0000042779344.143226.7896homo_sapiensENSP0000042908414.54098.82458
ENSG00000104517homo_sapiensENSP0000050768714.32787.46944homo_sapiensENSP0000042908422.615211.7899
ENSG00000104517homo_sapiensENSP0000038226916.74338.16092homo_sapiensENSP0000042908415.61277.60986
ENSG00000104517homo_sapiensENSP0000038319939.589722.8718homo_sapiensENSP0000042908413.79067.96713
ENSG00000104517homo_sapiensENSP0000026435028.027312.6953homo_sapiensENSP0000042908410.25374.64452
ENSG00000104517homo_sapiensENSP0000026243544.38526.0695homo_sapiensENSP0000042908411.86146.96677
ENSG00000104517homo_sapiensENSP0000049757242.660521.5596homo_sapiensENSP0000042908413.29056.71668
ENSG00000104517homo_sapiensENSP0000026285415.29498.52766homo_sapiensENSP0000042908423.901413.3262
ENSG00000104517homo_sapiensENSP0000026290335.643620.132homo_sapiensENSP0000042908411.57566.53805
ENSG00000104517homo_sapiensENSP0000035206943.333325.1724homo_sapiensENSP0000042908413.46917.82422

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000104517homo_sapiensENSP0000042908499.21499.0354nomascus_leucogenysENSNLEP0000000438399.96499.784
ENSG00000104517homo_sapiensENSP0000042908498.392398.1779pan_paniscusENSPPAP0000003623399.891299.6736
ENSG00000104517homo_sapiensENSP0000042908499.964399.8571pongo_abeliiENSPPYP0000002108599.964399.8571
ENSG00000104517homo_sapiensENSP0000042908499.964399.9285pan_troglodytesENSPTRP0000003502610099.9643
ENSG00000104517homo_sapiensENSP0000042908499.392699.2855gorilla_gorillaENSGGOP0000000302298.862898.7562
ENSG00000104517homo_sapiensENSP0000042908498.03597.2133ornithorhynchus_anatinusENSOANP0000002105899.420398.587
ENSG00000104517homo_sapiensENSP0000042908497.820696.8917sarcophilus_harrisiiENSSHAP0000002087399.202998.2609
ENSG00000104517homo_sapiensENSP0000042908462.772462.0936notamacropus_eugeniiENSMEUP0000000459962.839862.1602
ENSG00000104517homo_sapiensENSP0000042908478.956878.528choloepus_hoffmanniENSCHOP0000001216379.61179.1787
ENSG00000104517homo_sapiensENSP0000042908497.749296.5702dasypus_novemcinctusENSDNOP0000000614897.889196.7084
ENSG00000104517homo_sapiensENSP0000042908494.89194.0336erinaceus_europaeusENSEEUP0000001243895.677294.8127
ENSG00000104517homo_sapiensENSP0000042908474.598173.9193echinops_telfairiENSETEP0000001652575.679674.9909
ENSG00000104517homo_sapiensENSP0000042908499.857199.6427callithrix_jacchusENSCJAP0000002955799.785899.5716
ENSG00000104517homo_sapiensENSP0000042908499.892899.7142cercocebus_atysENSCATP0000002498799.821599.643
ENSG00000104517homo_sapiensENSP0000042908499.964399.7856macaca_fascicularisENSMFAP0000002645099.964399.7856
ENSG00000104517homo_sapiensENSP0000042908499.964399.7856macaca_mulattaENSMMUP0000002732899.714999.5367
ENSG00000104517homo_sapiensENSP0000042908499.928599.7142macaca_nemestrinaENSMNEP0000000978799.431299.2179
ENSG00000104517homo_sapiensENSP0000042908499.964399.7856papio_anubisENSPANP0000003974599.964399.7856
ENSG00000104517homo_sapiensENSP0000042908499.964399.7856mandrillus_leucophaeusENSMLEP0000003200499.964399.7856
ENSG00000104517homo_sapiensENSP0000042908483.029782.6009tursiops_truncatusENSTTRP0000000046983.148582.7191
ENSG00000104517homo_sapiensENSP0000042908497.963697.4991vulpes_vulpesENSVVUP0000002270599.781799.3086
ENSG00000104517homo_sapiensENSP0000042908499.392698.1779mus_spretusMGP_SPRETEiJ_P003989099.428298.213
ENSG00000104517homo_sapiensENSP0000042908499.714299.214equus_asinusENSEASP0000500360299.749899.2495
ENSG00000104517homo_sapiensENSP0000042908499.321298.7495capra_hircusENSCHIP0000002347199.250398.679
ENSG00000104517homo_sapiensENSP0000042908432.118631.8685loxodonta_africanaENSLAFP0000002718099.446998.6726
ENSG00000104517homo_sapiensENSP0000042908432.225831.9757loxodonta_africanaENSLAFP0000002039197.724896.9664
ENSG00000104517homo_sapiensENSP0000042908499.857199.3926panthera_leoENSPLOP0000001385599.892899.4282
ENSG00000104517homo_sapiensENSP0000042908499.071198.6781ailuropoda_melanoleucaENSAMEP0000001567099.85699.4598
ENSG00000104517homo_sapiensENSP0000042908499.857199.3569bos_indicus_hybridENSBIXP0000503222899.892899.3924
ENSG00000104517homo_sapiensENSP0000042908498.535297.9278oryctolagus_cuniculusENSOCUP0000000740899.602798.9888
ENSG00000104517homo_sapiensENSP0000042908499.392698.7853equus_caballusENSECAP0000005181798.512797.9108
ENSG00000104517homo_sapiensENSP0000042908499.821499.3569canis_lupus_familiarisENSCAFP0084501055699.85799.3924
ENSG00000104517homo_sapiensENSP0000042908498.892598.428panthera_pardusENSPPRP0000000543399.891799.4226
ENSG00000104517homo_sapiensENSP0000042908498.892598.4637marmota_marmota_marmotaENSMMMP0000001849099.675999.2438
ENSG00000104517homo_sapiensENSP0000042908418.506618.3994balaenoptera_musculusENSBMSP0001002396710099.4209
ENSG00000104517homo_sapiensENSP0000042908491.8989.8535cavia_porcellusENSCPOP0000000865097.093294.9415
ENSG00000104517homo_sapiensENSP0000042908499.857199.3926felis_catusENSFCAP0000001041899.892899.4282
ENSG00000104517homo_sapiensENSP0000042908482.029381.279ursus_americanusENSUAMP0000002080598.498597.5976
ENSG00000104517homo_sapiensENSP0000042908418.828218.721ursus_americanusENSUAMP0000002303510099.4307
ENSG00000104517homo_sapiensENSP0000042908496.927595.7842monodelphis_domesticaENSMODP0000000738998.154896.9971
ENSG00000104517homo_sapiensENSP0000042908418.828218.721bison_bison_bisonENSBBBP0000000467810099.4307
ENSG00000104517homo_sapiensENSP0000042908499.821499.4284monodon_monocerosENSMMNP0001501549699.85799.4639
ENSG00000104517homo_sapiensENSP0000042908498.392397.9636sus_scrofaENSSSCP0000002953899.710499.2759
ENSG00000104517homo_sapiensENSP0000042908499.749999.2855microcebus_murinusENSMICP0000003117499.749999.2855
ENSG00000104517homo_sapiensENSP0000042908499.321298.2494octodon_degusENSODEP0000000152599.356798.2845
ENSG00000104517homo_sapiensENSP0000042908499.60798.821jaculus_jaculusENSJJAP0000000992399.642698.8563
ENSG00000104517homo_sapiensENSP0000042908499.821499.3212ovis_aries_rambouilletENSOARP0002002752599.85799.3567
ENSG00000104517homo_sapiensENSP0000042908497.427797.0347ursus_maritimusENSUMAP0000002709399.81799.4143
ENSG00000104517homo_sapiensENSP0000042908473.276272.4187ochotona_princepsENSOPRP0000000419774.204173.3357
ENSG00000104517homo_sapiensENSP0000042908499.821499.4284delphinapterus_leucasENSDLEP0000000272699.785799.3929
ENSG00000104517homo_sapiensENSP0000042908499.821499.4284physeter_catodonENSPCTP0000500632999.85799.4639
ENSG00000104517homo_sapiensENSP0000042908499.285598.1065mus_caroliMGP_CAROLIEiJ_P003810999.320998.1415
ENSG00000104517homo_sapiensENSP0000042908499.392698.2136mus_musculusENSMUSP0000015429399.428298.2487
ENSG00000104517homo_sapiensENSP0000042908499.321298.3566dipodomys_ordiiENSDORP0000002496699.463398.4973
ENSG00000104517homo_sapiensENSP0000042908490.71190.2822mustela_putorius_furoENSMPUP0000001502799.803599.3318
ENSG00000104517homo_sapiensENSP0000042908499.928599.7499aotus_nancymaaeENSANAP0000002954499.857299.6787
ENSG00000104517homo_sapiensENSP0000042908499.964399.7499saimiri_boliviensis_boliviensisENSSBOP0000001781599.964399.7499
ENSG00000104517homo_sapiensENSP0000042908488.067287.6742vicugna_pacosENSVPAP0000000779392.011991.6013
ENSG00000104517homo_sapiensENSP0000042908499.749999.5713chlorocebus_sabaeusENSCSAP0000000814799.964299.7852
ENSG00000104517homo_sapiensENSP0000042908480.635980.1715tupaia_belangeriENSTBEP0000001369082.583282.1076
ENSG00000104517homo_sapiensENSP0000042908499.356997.9993mesocricetus_auratusENSMAUP0000002106599.392498.0343
ENSG00000104517homo_sapiensENSP0000042908499.821499.4284phocoena_sinusENSPSNP0000002721599.85799.4639
ENSG00000104517homo_sapiensENSP0000042908499.678599.2855camelus_dromedariusENSCDRP0000502312799.856899.4631
ENSG00000104517homo_sapiensENSP0000042908499.178398.6424carlito_syrichtaENSTSYP0000001049499.072198.5368
ENSG00000104517homo_sapiensENSP0000042908498.82198.1779panthera_tigris_altaicaENSPTIP0000001813099.711699.0627
ENSG00000104517homo_sapiensENSP0000042908499.464198.3923rattus_norvegicusENSRNOP0000009707099.499698.4274
ENSG00000104517homo_sapiensENSP0000042908499.785699.3569prolemur_simusENSPSMP0000001979599.7599.3214
ENSG00000104517homo_sapiensENSP0000042908499.071197.9993microtus_ochrogasterENSMOCP0000002296399.106598.0343
ENSG00000104517homo_sapiensENSP0000042908485.99585.3162sorex_araneusENSSARP0000000017086.832686.1472
ENSG00000104517homo_sapiensENSP0000042908497.499196.6059peromyscus_maniculatus_bairdiiENSPEMP0000002393397.3696.4681
ENSG00000104517homo_sapiensENSP0000042908499.106898.5709bos_mutusENSBMUP0000003505199.142298.6061
ENSG00000104517homo_sapiensENSP0000042908498.642497.4634mus_spicilegusENSMSIP0000003563599.423898.2355
ENSG00000104517homo_sapiensENSP0000042908494.426692.5331cricetulus_griseus_chok1gshdENSCGRP0000100271298.070596.1039
ENSG00000104517homo_sapiensENSP0000042908484.101583.7085pteropus_vampyrusENSPVAP0000001193084.161683.7683
ENSG00000104517homo_sapiensENSP0000042908498.892598.3208myotis_lucifugusENSMLUP0000000743099.604299.0284
ENSG00000104517homo_sapiensENSP0000042908499.21498.2494vombatus_ursinusENSVURP0001000925899.249598.2845
ENSG00000104517homo_sapiensENSP0000042908499.642799.1783rhinolophus_ferrumequinumENSRFEP0001002981899.856899.3913
ENSG00000104517homo_sapiensENSP0000042908498.928298.4995neovison_visonENSNVIP0000000138998.963598.5347
ENSG00000104517homo_sapiensENSP0000042908499.857199.3569bos_taurusENSBTAP0000002826299.892899.3924
ENSG00000104517homo_sapiensENSP0000042908496.391695.8914rhinopithecus_bietiENSRBIP0000002992298.936698.4232
ENSG00000104517homo_sapiensENSP0000042908499.785699.3212canis_lupus_dingoENSCAFP0002000339299.785699.3212
ENSG00000104517homo_sapiensENSP0000042908418.828218.721sciurus_vulgarisENSSVLP0000500030110099.4307
ENSG00000104517homo_sapiensENSP0000042908494.605293.6763phascolarctos_cinereusENSPCIP0000001233399.250498.2759
ENSG00000104517homo_sapiensENSP0000042908477.563477.1347procavia_capensisENSPCAP0000000131677.702277.2727
ENSG00000104517homo_sapiensENSP0000042908499.785699.3212nannospalax_galiliENSNGAP0000000237799.821399.3567
ENSG00000104517homo_sapiensENSP0000042908499.857199.3212bos_grunniensENSBGRP0000001433999.892899.3567
ENSG00000104517homo_sapiensENSP0000042908498.570997.5706chinchilla_lanigeraENSCLAP0000000799098.71297.7102
ENSG00000104517homo_sapiensENSP0000042908499.821499.3212cervus_hanglu_yarkandensisENSCHYP0000002688299.821499.3212
ENSG00000104517homo_sapiensENSP0000042908499.714299.214catagonus_wagneriENSCWAP0000002151999.749899.2495
ENSG00000104517homo_sapiensENSP0000042908498.82198.428ictidomys_tridecemlineatusENSSTOP0000000484599.424999.0295
ENSG00000104517homo_sapiensENSP0000042908499.785699.3212otolemur_garnettiiENSOGAP0000000401699.85799.3922
ENSG00000104517homo_sapiensENSP0000042908499.928599.7499cebus_imitatorENSCCAP0000003872199.964399.7856
ENSG00000104517homo_sapiensENSP0000042908499.571399.214urocitellus_parryiiENSUPAP0001001559299.606999.2495
ENSG00000104517homo_sapiensENSP0000042908499.749999.2497moschus_moschiferusENSMMSP0000000385599.785699.2852
ENSG00000104517homo_sapiensENSP0000042908498.999698.6781rhinopithecus_roxellanaENSRROP0000003489799.176898.8547
ENSG00000104517homo_sapiensENSP0000042908499.321298.2494mus_pahariMGP_PahariEiJ_P004149099.392298.3196
ENSG00000104517homo_sapiensENSP0000042908498.785398.1065propithecus_coquereliENSPCOP0000000658399.603798.9193
ENSG00000104517homo_sapiensENSP0000042908461.271942.5866drosophila_melanogasterFBpp030867159.404241.2885
ENSG00000104517homo_sapiensENSP0000042908459.16442.7295ciona_intestinalisENSCINP0000001760758.890542.532
ENSG00000104517homo_sapiensENSP0000042908445.123338.7638petromyzon_marinusENSPMAP0000000254885.337873.3108
ENSG00000104517homo_sapiensENSP0000042908496.105891.89callorhinchus_miliiENSCMIP0000000916696.277792.0544
ENSG00000104517homo_sapiensENSP0000042908496.963294.2479latimeria_chalumnaeENSLACP0000001378797.380794.6537
ENSG00000104517homo_sapiensENSP0000042908496.141592.8903lepisosteus_oculatusENSLOCP0000001211893.926790.7504
ENSG00000104517homo_sapiensENSP0000042908494.390989.8178clupea_harengusENSCHAP0000004122994.627590.043
ENSG00000104517homo_sapiensENSP0000042908494.676790.1036danio_rerioENSDARP0000003351094.812290.2326
ENSG00000104517homo_sapiensENSP0000042908494.212289.3891carassius_auratusENSCARP0000000682793.610288.8179
ENSG00000104517homo_sapiensENSP0000042908494.426689.532carassius_auratusENSCARP0000011087394.595689.6922
ENSG00000104517homo_sapiensENSP0000042908485.959381.2076astyanax_mexicanusENSAMXP0000002064994.761789.5234
ENSG00000104517homo_sapiensENSP0000042908481.600676.8846ictalurus_punctatusENSIPUP0000003441894.185688.7423
ENSG00000104517homo_sapiensENSP0000042908494.49890.1393esox_luciusENSELUP0000005153194.70190.333
ENSG00000104517homo_sapiensENSP0000042908481.564876.9203electrophorus_electricusENSEEEP0000002042294.299988.9302
ENSG00000104517homo_sapiensENSP0000042908494.49889.7821oncorhynchus_kisutchENSOKIP0000500051794.667189.9427
ENSG00000104517homo_sapiensENSP0000042908494.748189.925oncorhynchus_kisutchENSOKIP0000501848294.748189.925
ENSG00000104517homo_sapiensENSP0000042908493.890789.1747oncorhynchus_mykissENSOMYP0000000773994.159889.4303
ENSG00000104517homo_sapiensENSP0000042908494.533889.7106oncorhynchus_mykissENSOMYP0000007919292.874788.1362
ENSG00000104517homo_sapiensENSP0000042908494.676789.925salmo_salarENSSSAP0000005051692.077887.4566
ENSG00000104517homo_sapiensENSP0000042908494.212289.4248salmo_salarENSSSAP0000013801192.364387.6708
ENSG00000104517homo_sapiensENSP0000042908494.676789.8892salmo_truttaENSSTUP0000005682094.373289.6011
ENSG00000104517homo_sapiensENSP0000042908493.819289.0318salmo_truttaENSSTUP0000005496093.518588.7464
ENSG00000104517homo_sapiensENSP0000042908494.462389.8892gadus_morhuaENSGMOP0000004688991.965287.513
ENSG00000104517homo_sapiensENSP0000042908485.852181.4934fundulus_heteroclitusENSFHEP0000001785694.792989.9803
ENSG00000104517homo_sapiensENSP0000042908494.569589.6034poecilia_reticulataENSPREP0000002474892.844687.9691
ENSG00000104517homo_sapiensENSP0000042908481.922177.5277xiphophorus_maculatusENSXMAP0000000246394.556789.4845
ENSG00000104517homo_sapiensENSP000004290842.750982.6438xiphophorus_maculatusENSXMAP0000003062293.902490.2439
ENSG00000104517homo_sapiensENSP0000042908494.676789.9607oryzias_latipesENSORLP0000004033092.689888.0728
ENSG00000104517homo_sapiensENSP0000042908494.212289.5677cyclopterus_lumpusENSCLMP0000503971294.313389.6638
ENSG00000104517homo_sapiensENSP0000042908494.140889.7106oreochromis_niloticusENSONIP0000002069394.61490.1616
ENSG00000104517homo_sapiensENSP0000042908482.315178.3137haplochromis_burtoniENSHBUP0000001952694.971190.3545
ENSG00000104517homo_sapiensENSP0000042908494.855390.318astatotilapia_callipteraENSACLP0000001653392.994788.5464
ENSG00000104517homo_sapiensENSP0000042908494.569589.9607sparus_aurataENSSAUP0001002242792.779588.258
ENSG00000104517homo_sapiensENSP0000042908493.676389.2104lates_calcariferENSLCAP0001004663194.588790.0794
ENSG00000104517homo_sapiensENSP0000042908497.892195.1768xenopus_tropicalisENSXETP0000008643797.404994.7032
ENSG00000104517homo_sapiensENSP0000042908499.142598.2136chrysemys_picta_belliiENSCPBP0000003994199.391198.4599
ENSG00000104517homo_sapiensENSP0000042908413.147612.8617sphenodon_punctatusENSSPUP0000001171297.612795.4907
ENSG00000104517homo_sapiensENSP0000042908417.899317.7921sphenodon_punctatusENSSPUP0000001173298.62298.0315
ENSG00000104517homo_sapiensENSP0000042908413.897813.6835sphenodon_punctatusENSSPUP0000001171898.48196.962
ENSG00000104517homo_sapiensENSP0000042908497.856496.463crocodylus_porosusENSCPRP0000500716198.41997.0176
ENSG00000104517homo_sapiensENSP0000042908498.070796.463laticauda_laticaudataENSLLTP0000000054198.316696.7049
ENSG00000104517homo_sapiensENSP0000042908489.710688.2101notechis_scutatusENSNSUP0000001684398.702897.0519
ENSG00000104517homo_sapiensENSP0000042908498.678197.1061pseudonaja_textilisENSPTXP0000000135698.713497.1408
ENSG00000104517homo_sapiensENSP000004290842.822442.82244anas_platyrhynchos_platyrhynchosENSAPLP00000030691100100
ENSG00000104517homo_sapiensENSP0000042908469.167668.4887anas_platyrhynchos_platyrhynchosENSAPLP0000000380899.129598.1567
ENSG00000104517homo_sapiensENSP0000042908498.963997.7135gallus_gallusENSGALP0001001657798.681997.435
ENSG00000104517homo_sapiensENSP0000042908498.142296.8203meleagris_gallopavoENSMGAP0000001296399.062497.7281
ENSG00000104517homo_sapiensENSP0000042908498.678197.4634serinus_canariaENSSCAP0000000781798.46797.2549
ENSG00000104517homo_sapiensENSP0000042908499.285598.1422parus_majorENSPMJP0000001329799.214698.0721
ENSG00000104517homo_sapiensENSP0000042908498.03596.7488anolis_carolinensisENSACAP0000003365699.097197.797
ENSG00000104517homo_sapiensENSP0000042908482.136578.0636neolamprologus_brichardiENSNBRP0000000262094.531289.8438
ENSG00000104517homo_sapiensENSP0000042908497.927896.3558naja_najaENSNNAP0000001739698.739297.1542
ENSG00000104517homo_sapiensENSP0000042908498.963997.8564podarcis_muralisENSPMRP0000003160098.999397.8913
ENSG00000104517homo_sapiensENSP0000042908498.42897.1061geospiza_fortisENSGFOP0000001960098.745597.4194
ENSG00000104517homo_sapiensENSP0000042908499.249798.035taeniopygia_guttataENSTGUP0000001247999.178997.965
ENSG00000104517homo_sapiensENSP0000042908495.534192.1758erpetoichthys_calabaricusENSECRP0000001887796.221792.8391
ENSG00000104517homo_sapiensENSP0000042908492.92688.3173kryptolebias_marmoratusENSKMAP0000000214494.857890.1532
ENSG00000104517homo_sapiensENSP0000042908498.856797.5348salvator_merianaeENSSMRP0000002741997.84396.5347
ENSG00000104517homo_sapiensENSP0000042908485.637781.4934amphilophus_citrinellusENSACIP0000000497494.556289.9803
ENSG00000104517homo_sapiensENSP0000042908494.605289.9964dicentrarchus_labraxENSDLAP0000500863992.814688.293
ENSG00000104517homo_sapiensENSP0000042908485.137681.0289amphiprion_perculaENSAPEP0000001118194.902490.3226
ENSG00000104517homo_sapiensENSP0000042908411.361210.7181oryzias_sinensisENSOSIP0000002499093.529488.2353
ENSG00000104517homo_sapiensENSP0000042908498.42897.5348pelodiscus_sinensisENSPSIP0000001506298.993998.0956
ENSG00000104517homo_sapiensENSP0000042908499.285598.3566gopherus_evgoodeiENSGEVP0000501380699.320998.3917
ENSG00000104517homo_sapiensENSP0000042908498.213697.1776chelonoidis_abingdoniiENSCABP0000001661698.813897.7714
ENSG00000104517homo_sapiensENSP0000042908485.816481.5648seriola_dumeriliENSSDUP0000001114395.015890.3085
ENSG00000104517homo_sapiensENSP0000042908495.355594.1765struthio_camelus_australisENSSCUP0000001994998.998597.7745
ENSG00000104517homo_sapiensENSP0000042908499.285598.2136anser_brachyrhynchusENSABRP0000000928599.214698.1435
ENSG00000104517homo_sapiensENSP0000042908493.390588.5316gasterosteus_aculeatusENSGACP0000000618794.368289.4585
ENSG00000104517homo_sapiensENSP0000042908494.283789.5677cynoglossus_semilaevisENSCSEP0000001322390.718586.1808
ENSG00000104517homo_sapiensENSP0000042908486.209481.6363poecilia_formosaENSPFOP0000001333094.442389.4325
ENSG00000104517homo_sapiensENSP0000042908494.712490.2108myripristis_murdjanENSMMDP0000504310294.509890.0178
ENSG00000104517homo_sapiensENSP0000042908493.783588.9246sander_luciopercaENSSLUP0000001356794.187389.3075
ENSG00000104517homo_sapiensENSP0000042908490.31889.4248strigops_habroptilaENSSHBP0000500160699.29398.3111
ENSG00000104517homo_sapiensENSP0000042908412.861712.433amphiprion_ocellarisENSAOCP0000000687597.297394.0541
ENSG00000104517homo_sapiensENSP0000042908498.463797.3205terrapene_carolina_triunguisENSTMTP0000000378198.428697.2857
ENSG00000104517homo_sapiensENSP0000042908493.569188.8532hucho_huchoENSHHUP0000006496393.770189.044
ENSG00000104517homo_sapiensENSP0000042908494.462389.6034hucho_huchoENSHHUP0000007521194.361289.5075
ENSG00000104517homo_sapiensENSP0000042908494.355189.5677betta_splendensENSBSLP0000005237692.699287.9958
ENSG00000104517homo_sapiensENSP0000042908484.744680.3144pygocentrus_nattereriENSPNAP0000000300894.426889.4904
ENSG00000104517homo_sapiensENSP0000042908494.605289.8178anabas_testudineusENSATEP0000003607594.672989.882
ENSG00000104517homo_sapiensENSP0000042908420.400115.4341ciona_savignyiENSCSAVP0000000176963.727748.2143
ENSG00000104517homo_sapiensENSP0000042908424.758817.7206ciona_savignyiENSCSAVP0000000174555.842139.9678
ENSG00000104517homo_sapiensENSP0000042908494.676789.9964seriola_lalandi_dorsalisENSSLDP0000001653893.244288.6348
ENSG00000104517homo_sapiensENSP0000042908494.069389.0675labrus_bergyltaENSLBEP0000003282692.030887.1374
ENSG00000104517homo_sapiensENSP0000042908482.315178.3137pundamilia_nyerereiENSPNYP0000000547594.697990.0945
ENSG00000104517homo_sapiensENSP0000042908493.997989.1032mastacembelus_armatusENSMAMP0000005970694.301189.3907
ENSG00000104517homo_sapiensENSP0000042908485.494881.2433stegastes_partitusENSSPAP0000002016394.622489.917
ENSG00000104517homo_sapiensENSP0000042908494.748189.925oncorhynchus_tshawytschaENSOTSP0000509100294.680589.8608
ENSG00000104517homo_sapiensENSP0000042908493.926489.139oncorhynchus_tshawytschaENSOTSP0000508799494.466489.6515
ENSG00000104517homo_sapiensENSP0000042908494.069389.5677acanthochromis_polyacanthusENSAPOP0000000584193.868189.3761
ENSG00000104517homo_sapiensENSP0000042908498.892597.9278aquila_chrysaetos_chrysaetosENSACCP0002000146199.282698.3142
ENSG00000104517homo_sapiensENSP0000042908494.319489.7463nothobranchius_furzeriENSNFUP0001502722692.92588.4196
ENSG00000104517homo_sapiensENSP0000042908485.816481.6006cyprinodon_variegatusENSCVAP0000003209594.753490.0986
ENSG00000104517homo_sapiensENSP0000042908494.676790.1036denticeps_clupeoidesENSDCDP0000002908694.94890.3619
ENSG00000104517homo_sapiensENSP0000042908494.605290.0322larimichthys_croceaENSLCRP0000504201792.814688.3281
ENSG00000104517homo_sapiensENSP0000042908494.247989.2462takifugu_rubripesENSTRUP0000005633992.334687.4344
ENSG00000104517homo_sapiensENSP0000042908498.713897.4634ficedula_albicollisENSFALP0000000615098.925997.6728
ENSG00000104517homo_sapiensENSP0000042908485.673581.0289hippocampus_comesENSHCOP0000002452194.446689.3265
ENSG00000104517homo_sapiensENSP0000042908494.426689.6034cyprinus_carpio_carpioENSCCRP0000010236493.557588.7788
ENSG00000104517homo_sapiensENSP0000042908494.426689.6034cyprinus_carpio_carpioENSCCRP0000002711393.856589.0625
ENSG00000104517homo_sapiensENSP0000042908498.785397.4634coturnix_japonicaENSCJPP0000500491799.068497.7427
ENSG00000104517homo_sapiensENSP0000042908481.850777.5634poecilia_latipinnaENSPLAP0000002324194.786989.8221
ENSG00000104517homo_sapiensENSP0000042908478.313773.2404sinocyclocheilus_grahamiENSSGRP0000004522690.841384.9565
ENSG00000104517homo_sapiensENSP0000042908410.25379.6463sinocyclocheilus_grahamiENSSGRP0000000957495.033189.404
ENSG00000104517homo_sapiensENSP0000042908472.847467.7028sinocyclocheilus_grahamiENSSGRP0000003625991.148984.7117
ENSG00000104517homo_sapiensENSP0000042908486.173682.0293maylandia_zebraENSMZEP0000503406395.072990.5006
ENSG00000104517homo_sapiensENSP0000042908490.353785.1733tetraodon_nigroviridisENSTNIP0000001628293.736188.3617
ENSG00000104517homo_sapiensENSP0000042908491.425585.1376paramormyrops_kingsleyaeENSPKIP0000003823791.654785.351
ENSG00000104517homo_sapiensENSP0000042908480.278775.2412paramormyrops_kingsleyaeENSPKIP0000002171094.372188.4502
ENSG00000104517homo_sapiensENSP0000042908493.676388.9603scleropages_formosusENSSFOP0001506913094.147289.4075
ENSG00000104517homo_sapiensENSP0000042908497.463494.6767leptobrachium_leishanenseENSLLEP0000003809097.918295.1184
ENSG00000104517homo_sapiensENSP0000042908493.497788.9961scophthalmus_maximusENSSMAP0000007055494.544889.9928
ENSG00000104517homo_sapiensENSP000004290842.822442.82244oryzias_melastigmaENSOMEP00000013373100100
ENSG00000104517homo_sapiensENSP0000042908484.744680.4216oryzias_melastigmaENSOMEP0000003046794.690689.8603

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000209involved_in protein polyubiquitination2IBA,IDAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006281involved_in DNA repair1IEAHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response1IDAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0010628acts_upstream_of_or_within positive regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0033696involved_in heterochromatin boundary formation1IMPHomo_sapiens(9606)Process
GO:0034450enables ubiquitin-ubiquitin ligase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0042307involved_in positive regulation of protein import into nucleus1IMPHomo_sapiens(9606)Process
GO:0043130enables ubiquitin binding1IEAHomo_sapiens(9606)Function
GO:0048471located_in perinuclear region of cytoplasm1IDAHomo_sapiens(9606)Component
GO:0050847involved_in progesterone receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IDAHomo_sapiens(9606)Function
GO:0070936involved_in protein K48-linked ubiquitination1IDAHomo_sapiens(9606)Process
GO:0090263involved_in positive regulation of canonical Wnt signaling pathway2IBA,IMPHomo_sapiens(9606)Process
GO:0140861involved_in DNA repair-dependent chromatin remodeling1IMPHomo_sapiens(9606)Process

Expression