Functions and Diseases

RBP Type Canonical_RBPs
Diseases CHIKVSARS-COV-OC43FlavivirusesHIVIAVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions DUB
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000103194 Gene ID 9100 Accession 12608
Symbol USP10 Alias UBPO Full Name ubiquitin specific peptidase 10
Status Confidence Length 79928 bases Strand Plus strand
Position 16 : 84699995 - 84779922 RNA binding domain PAM2
Summary Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Phenotypes

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression