RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	snRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000103005	Gene ID	79650	Accession	25792
Symbol	USB1	Alias	PN;Mpn1;HVSL1;hMpn1;hUsb1;C16orf57	Full Name	U6 snRNA biogenesis phosphodiesterase 1
Status	Confidence	Length	22073 bases	Strand	Plus strand
Position	16 : 57999546 - 58021618	RNA binding domain	HVSL
Summary	This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000457322	HVSL	PF09749	9.2e-60	1
ENSP00000219281	HVSL	PF09749	1.1e-59	1
ENSP00000454928	HVSL	PF09749	2.8e-57	1
ENSP00000513726	HVSL	PF09749	2.8e-57	1
ENSP00000446143	HVSL	PF09749	2.6e-48	1
ENSP00000513727	HVSL	PF09749	2.1e-33	1
ENSP00000513729	HVSL	PF09749	4.1e-28	1
ENSP00000513760	HVSL	PF09749	2.6e-27	1
ENSP00000454692	HVSL	PF09749	4e-27	1
ENSP00000409792	HVSL	PF09749	6.6e-27	1
ENSP00000513728	HVSL	PF09749	1.5e-14	1
ENSP00000513730	HVSL	PF09749	1.5e-14	1
ENSP00000513732	HVSL	PF09749	6.2e-14	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome.	L Edward Huttlin	2015-07-16	Cell
28887445	Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities.	L Allison Didychuk	2017-09-08	Nature communications
32518066	Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes.	J Eric Montemayor	2020-10-01	RNA (New York, N.Y.)

Name	Transcript ID	bp	Protein	Translation ID
USB1-205	ENST00000561743	1135	214aa	ENSP00000454928
USB1-217	ENST00000698444	2117	214aa	ENSP00000513726
USB1-218	ENST00000698445	2489	228aa	ENSP00000513727
USB1-221	ENST00000698510	1402	170aa	ENSP00000513760
USB1-219	ENST00000698446	2216	90aa	ENSP00000513728
USB1-203	ENST00000539737	1212	247aa	ENSP00000446143
USB1-202	ENST00000423271	3051	186aa	ENSP00000409792
USB1-211	ENST00000565662	2168	162aa	ENSP00000513729
USB1-204	ENST00000561568	2227	252aa	ENSP00000457322
USB1-201	ENST00000219281	2248	265aa	ENSP00000219281
USB1-213	ENST00000566292	575	No protein	-
USB1-215	ENST00000569252	573	90aa	ENSP00000513730
USB1-206	ENST00000562534	562	50aa	ENSP00000513731
USB1-214	ENST00000568848	548	No protein	-
USB1-207	ENST00000563149	2254	163aa	ENSP00000454692
USB1-209	ENST00000564387	558	95aa	ENSP00000457302
USB1-208	ENST00000563207	464	No protein	-
USB1-220	ENST00000698447	2224	131aa	ENSP00000513732
USB1-216	ENST00000624720	2895	No protein	-
USB1-210	ENST00000565151	886	No protein	-
USB1-212	ENST00000566082	3888	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000103005

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000103005	homo_sapiens	ENSP00000219281	93.5849	92.4528	nomascus_leucogenys	ENSNLEP00000004042	99.2	98
ENSG00000103005	homo_sapiens	ENSP00000219281	99.6226	98.8679	pan_paniscus	ENSPPAP00000038854	99.6226	98.8679
ENSG00000103005	homo_sapiens	ENSP00000219281	98.4906	97.7358	pongo_abelii	ENSPPYP00000038740	98.4906	97.7358
ENSG00000103005	homo_sapiens	ENSP00000219281	92.0755	91.6981	pan_troglodytes	ENSPTRP00000087910	98.7854	98.3806
ENSG00000103005	homo_sapiens	ENSP00000219281	98.8679	98.4906	gorilla_gorilla	ENSGGOP00000039112	98.8679	98.4906
ENSG00000103005	homo_sapiens	ENSP00000219281	69.434	59.2453	ornithorhynchus_anatinus	ENSOANP00000019191	85.5814	73.0233
ENSG00000103005	homo_sapiens	ENSP00000219281	79.2453	68.3019	sarcophilus_harrisii	ENSSHAP00000022471	79.2453	68.3019
ENSG00000103005	homo_sapiens	ENSP00000219281	39.6226	34.3396	notamacropus_eugenii	ENSMEUP00000003039	69.0789	59.8684
ENSG00000103005	homo_sapiens	ENSP00000219281	64.5283	59.2453	erinaceus_europaeus	ENSEEUP00000000129	64.5283	59.2453
ENSG00000103005	homo_sapiens	ENSP00000219281	76.2264	70.9434	echinops_telfairi	ENSETEP00000015987	75.6554	70.412
ENSG00000103005	homo_sapiens	ENSP00000219281	97.7358	95.8491	callithrix_jacchus	ENSCJAP00000021571	97.7358	95.8491
ENSG00000103005	homo_sapiens	ENSP00000219281	97.7358	95.8491	cercocebus_atys	ENSCATP00000016521	97.7358	95.8491
ENSG00000103005	homo_sapiens	ENSP00000219281	98.1132	96.2264	macaca_fascicularis	ENSMFAP00000034949	98.1132	96.2264
ENSG00000103005	homo_sapiens	ENSP00000219281	98.1132	96.2264	macaca_mulatta	ENSMMUP00000047324	98.1132	96.2264
ENSG00000103005	homo_sapiens	ENSP00000219281	97.7358	95.8491	macaca_nemestrina	ENSMNEP00000039062	97.7358	95.8491
ENSG00000103005	homo_sapiens	ENSP00000219281	98.1132	96.2264	papio_anubis	ENSPANP00000033665	98.1132	96.2264
ENSG00000103005	homo_sapiens	ENSP00000219281	98.1132	96.2264	mandrillus_leucophaeus	ENSMLEP00000009136	98.1132	96.2264
ENSG00000103005	homo_sapiens	ENSP00000219281	50.9434	47.5472	tursiops_truncatus	ENSTTRP00000007988	50.9434	47.5472
ENSG00000103005	homo_sapiens	ENSP00000219281	88.6792	83.7736	vulpes_vulpes	ENSVVUP00000032720	74.8408	70.7006
ENSG00000103005	homo_sapiens	ENSP00000219281	89.0566	80	mus_spretus	MGP_SPRETEiJ_P0089166	88.3895	79.4007
ENSG00000103005	homo_sapiens	ENSP00000219281	79.2453	73.5849	equus_asinus	ENSEASP00005007499	56	52
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	83.0189	capra_hircus	ENSCHIP00000028989	89.434	83.0189
ENSG00000103005	homo_sapiens	ENSP00000219281	76.6038	66.7924	loxodonta_africana	ENSLAFP00000001894	75.4647	65.7993
ENSG00000103005	homo_sapiens	ENSP00000219281	91.6981	85.6604	panthera_leo	ENSPLOP00000017075	91.0112	85.0187
ENSG00000103005	homo_sapiens	ENSP00000219281	82.6415	76.2264	ailuropoda_melanoleuca	ENSAMEP00000039286	79.6364	73.4545
ENSG00000103005	homo_sapiens	ENSP00000219281	90.1887	83.7736	bos_indicus_hybrid	ENSBIXP00005036822	90.1887	83.7736
ENSG00000103005	homo_sapiens	ENSP00000219281	91.3208	86.4151	equus_caballus	ENSECAP00000017029	67.9775	64.3258
ENSG00000103005	homo_sapiens	ENSP00000219281	82.6415	77.3585	canis_lupus_familiaris	ENSCAFP00845003447	68.8679	64.4654
ENSG00000103005	homo_sapiens	ENSP00000219281	91.3208	85.283	panthera_pardus	ENSPPRP00000000479	90.6367	84.6442
ENSG00000103005	homo_sapiens	ENSP00000219281	91.3208	85.6604	marmota_marmota_marmota	ENSMMMP00000011030	88.6447	83.1502
ENSG00000103005	homo_sapiens	ENSP00000219281	90.1887	84.1509	balaenoptera_musculus	ENSBMSP00010027904	90.1887	84.1509
ENSG00000103005	homo_sapiens	ENSP00000219281	89.0566	83.0189	cavia_porcellus	ENSCPOP00000012903	88.7218	82.7068
ENSG00000103005	homo_sapiens	ENSP00000219281	91.6981	85.283	felis_catus	ENSFCAP00000002479	91.0112	84.6442
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	84.1509	ursus_americanus	ENSUAMP00000021431	88.4758	82.8996
ENSG00000103005	homo_sapiens	ENSP00000219281	69.8113	59.2453	monodelphis_domestica	ENSMODP00000017591	86.4486	73.3645
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	83.3962	bison_bison_bison	ENSBBBP00000017219	89.434	83.3962
ENSG00000103005	homo_sapiens	ENSP00000219281	90.1887	84.9057	monodon_monoceros	ENSMMNP00015008352	90.1887	84.9057
ENSG00000103005	homo_sapiens	ENSP00000219281	90.566	83.3962	sus_scrofa	ENSSSCP00000003027	89.8876	82.7715
ENSG00000103005	homo_sapiens	ENSP00000219281	93.2076	89.8113	microcebus_murinus	ENSMICP00000049846	93.2076	89.8113
ENSG00000103005	homo_sapiens	ENSP00000219281	88.3019	81.8868	octodon_degus	ENSODEP00000022069	88.3019	81.8868
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	85.6604	jaculus_jaculus	ENSJJAP00000021528	89.4737	85.3383
ENSG00000103005	homo_sapiens	ENSP00000219281	90.1887	83.3962	ovis_aries_rambouillet	ENSOARP00020010706	90.1887	83.3962
ENSG00000103005	homo_sapiens	ENSP00000219281	73.9623	69.434	ursus_maritimus	ENSUMAP00000029496	91.5888	85.9813
ENSG00000103005	homo_sapiens	ENSP00000219281	56.2264	50.9434	ochotona_princeps	ENSOPRP00000010763	64.2241	58.1897
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	84.5283	delphinapterus_leucas	ENSDLEP00000021663	89.8113	84.5283
ENSG00000103005	homo_sapiens	ENSP00000219281	90.566	84.9057	physeter_catodon	ENSPCTP00005027476	90.566	84.9057
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	80.3774	mus_caroli	MGP_CAROLIEiJ_P0085661	88.764	79.7753
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	80.7547	mus_musculus	ENSMUSP00000034245	88.764	80.1498
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	83.3962	dipodomys_ordii	ENSDORP00000024821	86.8132	80.9524
ENSG00000103005	homo_sapiens	ENSP00000219281	88.3019	81.8868	mustela_putorius_furo	ENSMPUP00000004647	83.5714	77.5
ENSG00000103005	homo_sapiens	ENSP00000219281	97.7358	95.0943	aotus_nancymaae	ENSANAP00000036252	97.7358	95.0943
ENSG00000103005	homo_sapiens	ENSP00000219281	97.3585	94.3396	saimiri_boliviensis_boliviensis	ENSSBOP00000025806	97.3585	94.3396
ENSG00000103005	homo_sapiens	ENSP00000219281	50.566	45.283	vicugna_pacos	ENSVPAP00000009149	67	60
ENSG00000103005	homo_sapiens	ENSP00000219281	97.7358	96.6038	chlorocebus_sabaeus	ENSCSAP00000001111	97.7358	96.6038
ENSG00000103005	homo_sapiens	ENSP00000219281	56.6038	53.9623	tupaia_belangeri	ENSTBEP00000001300	64.6552	61.6379
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	84.5283	mesocricetus_auratus	ENSMAUP00000005728	88.764	83.8951
ENSG00000103005	homo_sapiens	ENSP00000219281	82.2642	76.6038	phocoena_sinus	ENSPSNP00000030594	79.8535	74.359
ENSG00000103005	homo_sapiens	ENSP00000219281	89.0566	81.8868	camelus_dromedarius	ENSCDRP00005007558	88.0597	80.9701
ENSG00000103005	homo_sapiens	ENSP00000219281	93.9623	89.8113	carlito_syrichta	ENSTSYP00000031012	93.9623	89.8113
ENSG00000103005	homo_sapiens	ENSP00000219281	91.6981	85.283	panthera_tigris_altaica	ENSPTIP00000005222	91.0112	84.6442
ENSG00000103005	homo_sapiens	ENSP00000219281	90.566	83.0189	rattus_norvegicus	ENSRNOP00000017960	89.8876	82.397
ENSG00000103005	homo_sapiens	ENSP00000219281	93.5849	89.434	prolemur_simus	ENSPSMP00000012264	93.5849	89.434
ENSG00000103005	homo_sapiens	ENSP00000219281	91.3208	83.3962	microtus_ochrogaster	ENSMOCP00000027021	90.6367	82.7715
ENSG00000103005	homo_sapiens	ENSP00000219281	86.0377	78.1132	peromyscus_maniculatus_bairdii	ENSPEMP00000017183	85.0746	77.2388
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	83.7736	bos_mutus	ENSBMUP00000001961	89.8113	83.7736
ENSG00000103005	homo_sapiens	ENSP00000219281	89.0566	80	mus_spicilegus	ENSMSIP00000005733	88.3895	79.4007
ENSG00000103005	homo_sapiens	ENSP00000219281	90.566	84.5283	cricetulus_griseus_chok1gshd	ENSCGRP00001009083	89.5522	83.5821
ENSG00000103005	homo_sapiens	ENSP00000219281	86.4151	79.6226	pteropus_vampyrus	ENSPVAP00000004365	88.417	81.4672
ENSG00000103005	homo_sapiens	ENSP00000219281	81.1321	75.8491	myotis_lucifugus	ENSMLUP00000006756	93.0736	87.013
ENSG00000103005	homo_sapiens	ENSP00000219281	81.5094	69.8113	vombatus_ursinus	ENSVURP00010032779	78.5455	67.2727
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	83.7736	rhinolophus_ferrumequinum	ENSRFEP00010013634	91.5058	85.7143
ENSG00000103005	homo_sapiens	ENSP00000219281	88.6792	82.2642	neovison_vison	ENSNVIP00000018475	87.3606	81.0409
ENSG00000103005	homo_sapiens	ENSP00000219281	90.1887	83.7736	bos_taurus	ENSBTAP00000020923	90.1887	83.7736
ENSG00000103005	homo_sapiens	ENSP00000219281	90.1887	85.283	heterocephalus_glaber_female	ENSHGLP00000055615	87.5458	82.7839
ENSG00000103005	homo_sapiens	ENSP00000219281	90.9434	89.8113	rhinopithecus_bieti	ENSRBIP00000042358	97.5708	96.3563
ENSG00000103005	homo_sapiens	ENSP00000219281	86.4151	81.8868	canis_lupus_dingo	ENSCAFP00020011494	86.0902	81.5789
ENSG00000103005	homo_sapiens	ENSP00000219281	92.4528	85.6604	sciurus_vulgaris	ENSSVLP00005025045	92.4528	85.6604
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	83.3962	nannospalax_galili	ENSNGAP00000006506	88.4758	82.1561
ENSG00000103005	homo_sapiens	ENSP00000219281	69.434	60.7547	bos_grunniens	ENSBGRP00000023972	50	43.75
ENSG00000103005	homo_sapiens	ENSP00000219281	61.8868	56.9811	chinchilla_lanigera	ENSCLAP00000010671	93.1818	85.7955
ENSG00000103005	homo_sapiens	ENSP00000219281	83.0189	76.2264	cervus_hanglu_yarkandensis	ENSCHYP00000022936	83.0189	76.2264
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	84.1509	catagonus_wagneri	ENSCWAP00000022372	88.4758	82.8996
ENSG00000103005	homo_sapiens	ENSP00000219281	90.9434	86.0377	ictidomys_tridecemlineatus	ENSSTOP00000006741	88.2784	83.5165
ENSG00000103005	homo_sapiens	ENSP00000219281	87.1698	83.0189	otolemur_garnettii	ENSOGAP00000002920	93.5223	89.0688
ENSG00000103005	homo_sapiens	ENSP00000219281	98.1132	96.2264	cebus_imitator	ENSCCAP00000008766	98.1132	96.2264
ENSG00000103005	homo_sapiens	ENSP00000219281	90.9434	85.6604	urocitellus_parryii	ENSUPAP00010014949	88.2784	83.1502
ENSG00000103005	homo_sapiens	ENSP00000219281	89.8113	83.3962	moschus_moschiferus	ENSMMSP00000005844	89.4737	83.0827
ENSG00000103005	homo_sapiens	ENSP00000219281	97.7358	96.6038	rhinopithecus_roxellana	ENSRROP00000009552	97.7358	96.6038
ENSG00000103005	homo_sapiens	ENSP00000219281	89.434	81.1321	mus_pahari	MGP_PahariEiJ_P0053911	88.764	80.5243
ENSG00000103005	homo_sapiens	ENSP00000219281	95.0943	90.566	propithecus_coquereli	ENSPCOP00000021207	95.0943	90.566
ENSG00000103005	homo_sapiens	ENSP00000219281	52.0755	36.2264	drosophila_melanogaster	FBpp0081590	53.4884	37.2093
ENSG00000103005	homo_sapiens	ENSP00000219281	50.1887	28.3019	ciona_intestinalis	ENSCINP00000021935	50.7634	28.626
ENSG00000103005	homo_sapiens	ENSP00000219281	61.8868	43.3962	petromyzon_marinus	ENSPMAP00000000514	69.1983	48.5232
ENSG00000103005	homo_sapiens	ENSP00000219281	62.2642	46.0377	eptatretus_burgeri	ENSEBUP00000009117	52.8846	39.1026
ENSG00000103005	homo_sapiens	ENSP00000219281	61.5094	46.7925	callorhinchus_milii	ENSCMIP00000027293	76.1682	57.9439
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	51.6981	latimeria_chalumnae	ENSLACP00000000118	61.2457	47.4048
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	52.4528	lepisosteus_oculatus	ENSLOCP00000000507	59.8662	46.4883
ENSG00000103005	homo_sapiens	ENSP00000219281	65.6604	49.0566	clupea_harengus	ENSCHAP00000031567	58.3893	43.6242
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	46.4151	danio_rerio	ENSDARP00000002264	64.1304	44.5652
ENSG00000103005	homo_sapiens	ENSP00000219281	65.6604	46.4151	carassius_auratus	ENSCARP00000060760	50.4348	35.6522
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	47.1698	carassius_auratus	ENSCARP00000112747	62.0567	44.3262
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	47.5472	astyanax_mexicanus	ENSAMXP00000040714	59.2715	41.7219
ENSG00000103005	homo_sapiens	ENSP00000219281	69.434	49.8113	ictalurus_punctatus	ENSIPUP00000012616	61.745	44.2953
ENSG00000103005	homo_sapiens	ENSP00000219281	64.5283	46.0377	esox_lucius	ENSELUP00000032882	61.7329	44.0433
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	46.7925	electrophorus_electricus	ENSEEEP00000034787	61.5385	43.3566
ENSG00000103005	homo_sapiens	ENSP00000219281	61.8868	46.0377	oncorhynchus_kisutch	ENSOKIP00005106918	55.4054	41.2162
ENSG00000103005	homo_sapiens	ENSP00000219281	42.2642	28.6792	oncorhynchus_kisutch	ENSOKIP00005076157	57.4359	38.9744
ENSG00000103005	homo_sapiens	ENSP00000219281	65.6604	48.6792	oncorhynchus_mykiss	ENSOMYP00000014852	54.375	40.3125
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	48.6792	salmo_salar	ENSSSAP00000165089	62.0567	45.7447
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	48.6792	salmo_trutta	ENSSTUP00000030493	62.0567	45.7447
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.9245	gadus_morhua	ENSGMOP00000058027	64.9446	46.8635
ENSG00000103005	homo_sapiens	ENSP00000219281	60.7547	43.3962	fundulus_heteroclitus	ENSFHEP00000028294	64.4	46
ENSG00000103005	homo_sapiens	ENSP00000219281	61.1321	44.5283	poecilia_reticulata	ENSPREP00000001460	65.587	47.7733
ENSG00000103005	homo_sapiens	ENSP00000219281	61.8868	44.9057	xiphophorus_maculatus	ENSXMAP00000032993	44.9315	32.6027
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	46.7925	oryzias_latipes	ENSORLP00000015620	64.3382	45.5882
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	49.0566	cyclopterus_lumpus	ENSCLMP00005028703	63.5379	46.9314
ENSG00000103005	homo_sapiens	ENSP00000219281	61.1321	46.7925	oreochromis_niloticus	ENSONIP00000013927	64.2857	49.2063
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	49.8113	haplochromis_burtoni	ENSHBUP00000026976	63.9286	47.1429
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	49.0566	astatotilapia_calliptera	ENSACLP00000030386	62.9893	46.2633
ENSG00000103005	homo_sapiens	ENSP00000219281	63.7736	45.283	sparus_aurata	ENSSAUP00010016316	52	36.9231
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	49.8113	lates_calcarifer	ENSLCAP00010037370	63.4752	46.8085
ENSG00000103005	homo_sapiens	ENSP00000219281	68.6792	50.566	xenopus_tropicalis	ENSXETP00000030208	71.0938	52.3438
ENSG00000103005	homo_sapiens	ENSP00000219281	77.7358	65.283	chrysemys_picta_bellii	ENSCPBP00000039092	74.1007	62.2302
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	55.4717	sphenodon_punctatus	ENSSPUP00000008678	83.6449	68.6916
ENSG00000103005	homo_sapiens	ENSP00000219281	74.717	62.6415	crocodylus_porosus	ENSCPRP00005021915	71.4801	59.9278
ENSG00000103005	homo_sapiens	ENSP00000219281	63.7736	53.5849	laticauda_laticaudata	ENSLLTP00000016214	56.3333	47.3333
ENSG00000103005	homo_sapiens	ENSP00000219281	69.0566	57.7358	notechis_scutatus	ENSNSUP00000010084	66.5455	55.6364
ENSG00000103005	homo_sapiens	ENSP00000219281	64.5283	53.5849	pseudonaja_textilis	ENSPTXP00000009790	79.1667	65.7407
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	55.8491	anas_platyrhynchos_platyrhynchos	ENSAPLP00000002197	81.9444	68.5185
ENSG00000103005	homo_sapiens	ENSP00000219281	70.566	55.0943	gallus_gallus	ENSGALP00010031047	56.1562	43.8438
ENSG00000103005	homo_sapiens	ENSP00000219281	60	48.3019	meleagris_gallopavo	ENSMGAP00000029590	70.0441	56.3877
ENSG00000103005	homo_sapiens	ENSP00000219281	69.434	57.3585	serinus_canaria	ENSSCAP00000008365	67.3993	55.6777
ENSG00000103005	homo_sapiens	ENSP00000219281	73.9623	59.6226	parus_major	ENSPMJP00000018710	50.646	40.8269
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	55.8491	anolis_carolinensis	ENSACAP00000024099	69.9605	58.498
ENSG00000103005	homo_sapiens	ENSP00000219281	61.8868	45.283	neolamprologus_brichardi	ENSNBRP00000011278	60.0733	43.956
ENSG00000103005	homo_sapiens	ENSP00000219281	72.8302	61.5094	naja_naja	ENSNNAP00000006398	68.9286	58.2143
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	56.9811	podarcis_muralis	ENSPMRP00000031769	69.3798	58.5271
ENSG00000103005	homo_sapiens	ENSP00000219281	48.6792	39.6226	geospiza_fortis	ENSGFOP00000018051	86	70
ENSG00000103005	homo_sapiens	ENSP00000219281	72.0755	58.8679	taeniopygia_guttata	ENSTGUP00000004926	38.7424	31.643
ENSG00000103005	homo_sapiens	ENSP00000219281	64.9057	48.3019	erpetoichthys_calabaricus	ENSECRP00000032185	60.1399	44.7552
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	50.1887	kryptolebias_marmoratus	ENSKMAP00000009586	62.8975	46.9965
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.1698	oryzias_javanicus	ENSOJAP00000005663	62.6335	44.484
ENSG00000103005	homo_sapiens	ENSP00000219281	64.5283	48.3019	amphilophus_citrinellus	ENSACIP00000015770	63.0996	47.2325
ENSG00000103005	homo_sapiens	ENSP00000219281	68.3019	49.8113	dicentrarchus_labrax	ENSDLAP00005003844	62.8472	45.8333
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	49.434	amphiprion_percula	ENSAPEP00000000396	63.1206	46.4539
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.1698	oryzias_sinensis	ENSOSIP00000001170	64.9446	46.1255
ENSG00000103005	homo_sapiens	ENSP00000219281	56.2264	44.1509	pelodiscus_sinensis	ENSPSIP00000004588	67.4208	52.9412
ENSG00000103005	homo_sapiens	ENSP00000219281	77.7358	64.5283	gopherus_evgoodei	ENSGEVP00005008172	75.4579	62.6374
ENSG00000103005	homo_sapiens	ENSP00000219281	72.4528	59.2453	chelonoidis_abingdonii	ENSCABP00000028830	71.3755	58.3643
ENSG00000103005	homo_sapiens	ENSP00000219281	64.5283	49.434	seriola_dumerili	ENSSDUP00000003989	63.5688	48.6989
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	49.0566	cottoperca_gobio	ENSCGOP00000002079	64.0288	46.7626
ENSG00000103005	homo_sapiens	ENSP00000219281	48.6792	41.1321	struthio_camelus_australis	ENSSCUP00000001823	86	72.6667
ENSG00000103005	homo_sapiens	ENSP00000219281	76.6038	63.3962	anser_brachyrhynchus	ENSABRP00000009331	74.9077	61.9926
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	48.3019	gasterosteus_aculeatus	ENSGACP00000004260	63.1769	46.2094
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.9245	cynoglossus_semilaevis	ENSCSEP00000021745	63.7681	46.0145
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	48.6792	poecilia_formosa	ENSPFOP00000011133	64.0288	46.4029
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	52.0755	myripristis_murdjan	ENSMMDP00005024179	62.6761	48.5915
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.9245	sander_lucioperca	ENSSLUP00000061117	62.8571	45.3571
ENSG00000103005	homo_sapiens	ENSP00000219281	74.717	61.1321	strigops_habroptila	ENSSHBP00005003709	76.1538	62.3077
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	49.0566	amphiprion_ocellaris	ENSAOCP00000010603	63.1206	46.0993
ENSG00000103005	homo_sapiens	ENSP00000219281	77.3585	63.7736	terrapene_carolina_triunguis	ENSTMTP00000000669	73.741	60.7914
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	49.0566	hucho_hucho	ENSHHUP00000056845	62.4113	46.0993
ENSG00000103005	homo_sapiens	ENSP00000219281	48.6792	34.717	hucho_hucho	ENSHHUP00000042222	57.8475	41.2556
ENSG00000103005	homo_sapiens	ENSP00000219281	64.5283	47.1698	betta_splendens	ENSBSLP00000038302	63.5688	46.4684
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.5472	pygocentrus_nattereri	ENSPNAP00000026428	59.8639	42.8571
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	50.1887	anabas_testudineus	ENSATEP00000013369	62.6335	47.331
ENSG00000103005	homo_sapiens	ENSP00000219281	49.8113	26.7925	ciona_savignyi	ENSCSAVP00000001568	48.1752	25.9124
ENSG00000103005	homo_sapiens	ENSP00000219281	65.6604	50.1887	seriola_lalandi_dorsalis	ENSSLDP00000017985	62.1429	47.5
ENSG00000103005	homo_sapiens	ENSP00000219281	61.1321	44.1509	labrus_bergylta	ENSLBEP00000010927	51.7572	37.3802
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	49.8113	pundamilia_nyererei	ENSPNYP00000029545	63.9286	47.1429
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	49.8113	mastacembelus_armatus	ENSMAMP00000022413	63.3094	47.482
ENSG00000103005	homo_sapiens	ENSP00000219281	67.1698	48.3019	stegastes_partitus	ENSSPAP00000009820	62.6761	45.0704
ENSG00000103005	homo_sapiens	ENSP00000219281	50.566	33.9623	oncorhynchus_tshawytscha	ENSOTSP00005060619	56.7797	38.1356
ENSG00000103005	homo_sapiens	ENSP00000219281	61.1321	45.283	oncorhynchus_tshawytscha	ENSOTSP00005071782	54.7297	40.5405
ENSG00000103005	homo_sapiens	ENSP00000219281	64.9057	47.9245	acanthochromis_polyacanthus	ENSAPOP00000009647	61.4286	45.3571
ENSG00000103005	homo_sapiens	ENSP00000219281	71.3208	58.4906	aquila_chrysaetos_chrysaetos	ENSACCP00020012392	56.0831	45.9941
ENSG00000103005	homo_sapiens	ENSP00000219281	65.283	48.3019	nothobranchius_furzeri	ENSNFUP00015039605	61.3475	45.3901
ENSG00000103005	homo_sapiens	ENSP00000219281	57.7358	41.1321	cyprinodon_variegatus	ENSCVAP00000024841	56.25	40.0735
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	46.4151	denticeps_clupeoides	ENSDCDP00000034464	61.9718	43.3099
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	50.9434	larimichthys_crocea	ENSLCRP00005055203	60.7639	46.875
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	47.9245	takifugu_rubripes	ENSTRUP00000070772	66.7924	47.9245
ENSG00000103005	homo_sapiens	ENSP00000219281	73.9623	60	ficedula_albicollis	ENSFALP00000007176	75.969	61.6279
ENSG00000103005	homo_sapiens	ENSP00000219281	66.0377	49.8113	hippocampus_comes	ENSHCOP00000025455	67.8295	51.1628
ENSG00000103005	homo_sapiens	ENSP00000219281	66.4151	47.1698	cyprinus_carpio_carpio	ENSCCRP00000123663	48.4848	34.4353
ENSG00000103005	homo_sapiens	ENSP00000219281	75.0943	61.1321	coturnix_japonica	ENSCJPP00005014650	79.2829	64.5418
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	48.6792	poecilia_latipinna	ENSPLAP00000023998	64.3885	46.4029
ENSG00000103005	homo_sapiens	ENSP00000219281	64.9057	42.2642	sinocyclocheilus_grahami	ENSSGRP00000050843	63.7037	41.4815
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	47.9245	sinocyclocheilus_grahami	ENSSGRP00000085793	63.9286	45.3571
ENSG00000103005	homo_sapiens	ENSP00000219281	67.5472	47.9245	sinocyclocheilus_grahami	ENSSGRP00000085791	63.9286	45.3571
ENSG00000103005	homo_sapiens	ENSP00000219281	66.7924	49.0566	maylandia_zebra	ENSMZEP00005013307	63.2143	46.4286
ENSG00000103005	homo_sapiens	ENSP00000219281	56.9811	44.1509	tetraodon_nigroviridis	ENSTNIP00000003852	61.1336	47.3684
ENSG00000103005	homo_sapiens	ENSP00000219281	63.0189	48.3019	paramormyrops_kingsleyae	ENSPKIP00000036616	55.1155	42.2442
ENSG00000103005	homo_sapiens	ENSP00000219281	68.6792	52.4528	scleropages_formosus	ENSSFOP00015037186	57.4132	43.8486
ENSG00000103005	homo_sapiens	ENSP00000219281	59.2453	41.1321	leptobrachium_leishanense	ENSLLEP00000039054	67.382	46.7811
ENSG00000103005	homo_sapiens	ENSP00000219281	56.6038	42.6415	scophthalmus_maximus	ENSSMAP00000046965	72.8155	54.8544
ENSG00000103005	homo_sapiens	ENSP00000219281	65.6604	46.7925	oryzias_melastigma	ENSOMEP00000029350	63.0435	44.9275

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000175	enables 3-5-RNA exonuclease activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0008380	involved_in RNA splicing	1	IMP	Homo_sapiens(9606)	Process
GO:0016829	enables lyase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0034472	involved_in snRNA 3-end processing	1	IMP	Homo_sapiens(9606)	Process
GO:0034477	involved_in U6 snRNA 3-end processing	3	IBA,IDA,IMP	Homo_sapiens(9606)	Process
GO:0045171	located_in intercellular bridge	1	IDA	Homo_sapiens(9606)	Component
GO:1990838	enables poly(U)-specific exoribonuclease activity, producing 3 uridine cyclic phosphate ends	1	IDA	Homo_sapiens(9606)	Function