RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000102021	Gene ID	51213	Accession	24971
Symbol	LUZP4	Alias	CT-8;CT28;CT-28;HOM-TES-85	Full Name	leucine zipper protein 4
Status	Confidence	Length	17849 bases	Strand	Plus strand
Position	X : 115289715 - 115307563	RNA binding domain	N.A.
Summary	This gene encodes a leucine-zipper protein that was first defined as a cancer testis antigens. The encoded protein is an RNA binding protein that interacts with the mRNA export receptor nuclear RNA export factor 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
25662211	Luzp4 defines a new mRNA export pathway in cancer cells.	Nicolas Viphakone	2015-02-27	Nucleic acids research
30623604	Bilateral striatal necrosis due to homoplasmic mitochondrial 3697G>A mutation presents with incomplete penetrance and sex bias.	Shanshan Zhong	2019-03-01	Molecular genetics & genomic medicine
30290229	The m⁶A‑methylase complex and mRNA export.	Simon Lesbirel	2019-03-01	Biochimica et biophysica acta. Gene regulatory mechanisms

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
LUZP4-202	ENST00000371921	1606	78aa	ENSP00000360989
LUZP4-201	ENST00000371920	1746	313aa	ENSP00000360988

Gene Model

Click here to download ENSG00000102021's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
9311	Echocardiography	5.86941972193777E-5	17903301
50490	Child Development Disorders, Pervasive	4.6329100E-006	-
50528	Child Development Disorders, Pervasive	4.6329100E-006	-
51228	Child Development Disorders, Pervasive	8.1837500E-006	-
51260	Child Development Disorders, Pervasive	8.1837500E-006	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000102021's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IEA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0051028	involved_in mRNA transport	1	IEA	Homo_sapiens(9606)	Process

Expression