RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2Dengue
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000101856	Gene ID	10857	Accession	16090
Symbol	PGRMC1	Alias	IZA;MPR;Dap1;HPR6.6	Full Name	progesterone receptor membrane component 1
Status	Confidence	Length	8222 bases	Strand	Plus strand
Position	X : 119236245 - 119244466	RNA binding domain	N.A.
Summary	This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
23781168	Progesterone receptor membrane component 1 and its role in ovarian follicle growth.	J John Peluso	2013-01-01	Frontiers in neuroscience
27846214	Proteomic Profiling for Identification of Novel Biomarkers Differentially Expressed in Human Ovaries from Polycystic Ovary Syndrome Patients.	Li Li	2016-01-01	PloS one
34435651	Hormone therapy for ovarian cancer: Emphasis on mechanisms and applications (Review).	Hongyi Li	2021-10-01	Oncology reports

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
PGRMC1-202	ENST00000535419	1762	143aa	ENSP00000442821
PGRMC1-201	ENST00000217971	1879	195aa	ENSP00000217971

Gene Model

Click here to download ENSG00000101856's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000101856's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001540	enables amyloid-beta binding	1	TAS	Homo_sapiens(9606)	Function
GO:0005496	enables steroid binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	IEA	Homo_sapiens(9606)	Component
GO:0005741	located_in mitochondrial outer membrane	1	ISS	Homo_sapiens(9606)	Component
GO:0005783	is_active_in endoplasmic reticulum	2	IBA,TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0006783	involved_in heme biosynthetic process	1	IDA	Homo_sapiens(9606)	Process
GO:0012505	is_active_in endomembrane system	1	IBA	Homo_sapiens(9606)	Component
GO:0016020	located_in membrane	2	HDA,IBA	Homo_sapiens(9606)	Component
GO:0020037	enables heme binding	1	IDA	Homo_sapiens(9606)	Function
GO:0030868	located_in smooth endoplasmic reticulum membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0035579	located_in specific granule membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0042803	enables protein homodimerization activity	1	IDA	Homo_sapiens(9606)	Function
GO:0043005	located_in neuron projection	1	ISS	Homo_sapiens(9606)	Component
GO:0043025	located_in neuronal cell body	1	ISS	Homo_sapiens(9606)	Component
GO:0044297	located_in cell body	1	ISS	Homo_sapiens(9606)	Component
GO:0045202	located_in synapse	1	ISS	Homo_sapiens(9606)	Component
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function

Expression