Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000101546 Gene ID 79863 Accession 26120
Symbol RBFA Alias HsT169;C18orf22 Full Name ribosome binding factor A
Status Confidence Length 16218 bases Strand Plus strand
Position 18 : 80034434 - 80050651 RNA binding domain N.A.
Summary Predicted to be involved in rRNA processing. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
28512204 The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome. Agata Rozanska 2017-06-13 The Biochemical journal
37207340 Miniature RNAs are embedded in an exceptionally protein-rich mitoribosome via an elaborate assembly pathway. Matus Valach 2023-07-07 Nucleic acids research
36620886 The recognition mode between hsRBFA and mitoribosome 12S rRNA during mitoribosomal biogenesis. Wanwan Zhou 2023-02-22 Nucleic acids research
35666428 1H, 13C, and 15N resonance assignments and solution structures of the KH domain of human ribosome binding factor A, mtRbfA, involved in mitochondrial ribosome biogenesis. Kanako Kuwasako 2022-10-01 Biomolecular NMR assignments

Transcripts

Name Transcript ID bp Protein Translation ID
RBFA-203 ENST00000586847 566 No protein -
RBFA-202 ENST00000306735 5590 343aa ENSP00000305696
RBFA-204 ENST00000591612 1587 No protein -
RBFA-201 ENST00000262197 1219 242aa ENSP00000262197
RBFA-205 ENST00000593019 1551 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000101546

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000101546homo_sapiensENSP0000030569694.752293.2945nomascus_leucogenysENSNLEP0000001021996.726295.2381
ENSG00000101546homo_sapiensENSP0000030569698.250797.9592pan_paniscusENSPPAP0000000886598.250797.9592
ENSG00000101546homo_sapiensENSP0000030569698.833898.2507pongo_abeliiENSPPYP0000001039898.833898.2507
ENSG00000101546homo_sapiensENSP0000030569698.542398.5423pan_troglodytesENSPTRP0000008418498.542398.5423
ENSG00000101546homo_sapiensENSP0000030569698.833897.9592gorilla_gorillaENSGGOP0000000307998.833897.9592
ENSG00000101546homo_sapiensENSP0000030569657.725941.9825ornithorhynchus_anatinusENSOANP0000004315756.733541.2607
ENSG00000101546homo_sapiensENSP0000030569662.682249.5627sarcophilus_harrisiiENSSHAP0000000098456.578944.7368
ENSG00000101546homo_sapiensENSP0000030569657.434446.6472dasypus_novemcinctusENSDNOP0000003438880.737765.5738
ENSG00000101546homo_sapiensENSP0000030569666.763855.9767dasypus_novemcinctusENSDNOP0000003318677.364964.8649
ENSG00000101546homo_sapiensENSP0000030569657.725947.5219echinops_telfairiENSETEP0000001473576.744263.1783
ENSG00000101546homo_sapiensENSP0000030569689.212886.0058callithrix_jacchusENSCJAP0000009224689.473786.2573
ENSG00000101546homo_sapiensENSP0000030569689.795986.5889callithrix_jacchusENSCJAP0000001861989.795986.5889
ENSG00000101546homo_sapiensENSP0000030569690.670685.7143cercocebus_atysENSCATP0000000330991.202386.217
ENSG00000101546homo_sapiensENSP0000030569691.836787.4636macaca_fascicularisENSMFAP0000002720860.114557.2519
ENSG00000101546homo_sapiensENSP0000030569692.128388.3382macaca_mulattaENSMMUP0000001950392.128388.3382
ENSG00000101546homo_sapiensENSP0000030569691.836788.0466macaca_nemestrinaENSMNEP0000002037391.836788.0466
ENSG00000101546homo_sapiensENSP0000030569691.253687.4636papio_anubisENSPANP0000000634091.788987.9765
ENSG00000101546homo_sapiensENSP0000030569688.338283.3819mandrillus_leucophaeusENSMLEP0000003468190.99185.8859
ENSG00000101546homo_sapiensENSP0000030569665.597757.7259tursiops_truncatusENSTTRP0000000857068.807360.5505
ENSG00000101546homo_sapiensENSP0000030569655.685143.4402vulpes_vulpesENSVVUP0000002584272.623656.654
ENSG00000101546homo_sapiensENSP0000030569671.13760.0583mus_spretusMGP_SPRETEiJ_P004917669.91459.0258
ENSG00000101546homo_sapiensENSP0000030569672.886365.8892equus_asinusENSEASP0000505395567.934861.413
ENSG00000101546homo_sapiensENSP0000030569665.597757.1429capra_hircusENSCHIP0000000916277.054867.1233
ENSG00000101546homo_sapiensENSP0000030569667.9359.1837loxodonta_africanaENSLAFP0000001264471.036661.8902
ENSG00000101546homo_sapiensENSP0000030569666.763858.309panthera_leoENSPLOP0000002786470.461561.5385
ENSG00000101546homo_sapiensENSP0000030569665.597757.4344bos_indicus_hybridENSBIXP0000502060177.054867.4658
ENSG00000101546homo_sapiensENSP0000030569672.594765.5977equus_caballusENSECAP0000000625667.66361.1413
ENSG00000101546homo_sapiensENSP0000030569667.9355.9767canis_lupus_familiarisENSCAFP0084500002270.392758.006
ENSG00000101546homo_sapiensENSP0000030569666.472357.7259panthera_pardusENSPPRP0000002409969.938760.7362
ENSG00000101546homo_sapiensENSP0000030569670.845559.4752marmota_marmota_marmotaENSMMMP0000002178170.028858.7896
ENSG00000101546homo_sapiensENSP0000030569667.055457.1429balaenoptera_musculusENSBMSP0001001309762.330653.1165
ENSG00000101546homo_sapiensENSP0000030569674.052563.5569cavia_porcellusENSCPOP0000000014973.198862.8242
ENSG00000101546homo_sapiensENSP0000030569668.513158.8921felis_catusENSFCAP0000004977261.518352.8796
ENSG00000101546homo_sapiensENSP0000030569672.011763.2653ursus_americanusENSUAMP0000003391772.861464.0118
ENSG00000101546homo_sapiensENSP0000030569665.889251.312monodelphis_domesticaENSMODP0000001495757.800545.0128
ENSG00000101546homo_sapiensENSP0000030569668.221658.8921monodon_monocerosENSMMNP0001500523160.154251.928
ENSG00000101546homo_sapiensENSP0000030569665.889257.4344microcebus_murinusENSMICP0000001088276.094366.33
ENSG00000101546homo_sapiensENSP0000030569672.594763.2653jaculus_jaculusENSJJAP0000001050371.757962.536
ENSG00000101546homo_sapiensENSP0000030569643.148737.0262ovis_aries_rambouilletENSOARP0002001464362.711953.8136
ENSG00000101546homo_sapiensENSP0000030569658.892150.1458ursus_maritimusENSUMAP0000000620568.94258.7031
ENSG00000101546homo_sapiensENSP0000030569667.638558.309delphinapterus_leucasENSDLEP0000000662159.640151.4139
ENSG00000101546homo_sapiensENSP0000030569667.9358.6006physeter_catodonENSPCTP0000502184973.968363.8095
ENSG00000101546homo_sapiensENSP0000030569671.428660.6414mus_caroliMGP_CAROLIEiJ_P004722070.605259.9424
ENSG00000101546homo_sapiensENSP0000030569671.720159.1837mus_musculusENSMUSP0000002546270.285758
ENSG00000101546homo_sapiensENSP0000030569653.061243.4402mustela_putorius_furoENSMPUP0000001656157.232746.8553
ENSG00000101546homo_sapiensENSP0000030569688.921385.1312aotus_nancymaaeENSANAP0000002365874.754971.5686
ENSG00000101546homo_sapiensENSP0000030569688.046684.5481saimiri_boliviensis_boliviensisENSSBOP0000001584088.304184.7953
ENSG00000101546homo_sapiensENSP0000030569691.545286.2974chlorocebus_sabaeusENSCSAP0000001427291.545286.2974
ENSG00000101546homo_sapiensENSP0000030569671.720160.9329mesocricetus_auratusENSMAUP0000000869570.285759.7143
ENSG00000101546homo_sapiensENSP0000030569667.346957.7259phocoena_sinusENSPSNP0000001664359.536151.0309
ENSG00000101546homo_sapiensENSP0000030569669.096260.3499camelus_dromedariusENSCDRP0000502892363.538955.496
ENSG00000101546homo_sapiensENSP0000030569672.594764.1399carlito_syrichtaENSTSYP0000001606372.80764.3275
ENSG00000101546homo_sapiensENSP0000030569656.851349.2711panthera_tigris_altaicaENSPTIP0000001053671.691262.1324
ENSG00000101546homo_sapiensENSP0000030569674.052562.0991rattus_norvegicusENSRNOP0000007176973.623261.7391
ENSG00000101546homo_sapiensENSP0000030569675.510267.3469prolemur_simusENSPSMP0000003477377.313468.9552
ENSG00000101546homo_sapiensENSP0000030569668.804757.7259microtus_ochrogasterENSMOCP0000002168967.816156.8966
ENSG00000101546homo_sapiensENSP0000030569671.428659.4752peromyscus_maniculatus_bairdiiENSPEMP0000002504570.402358.6207
ENSG00000101546homo_sapiensENSP0000030569665.597756.8513bos_mutusENSBMUP0000002435477.054866.7808
ENSG00000101546homo_sapiensENSP0000030569671.720160.0583mus_spicilegusENSMSIP0000000292364.062553.6458
ENSG00000101546homo_sapiensENSP0000030569671.720161.2245cricetulus_griseus_chok1gshdENSCGRP0000102508663.565954.2636
ENSG00000101546homo_sapiensENSP0000030569659.766851.6035pteropus_vampyrusENSPVAP0000000454660.650952.3669
ENSG00000101546homo_sapiensENSP0000030569675.510267.6385myotis_lucifugusENSMLUP0000000614674.639866.8588
ENSG00000101546homo_sapiensENSP0000030569654.810541.3994vombatus_ursinusENSVURP0001002665463.728848.1356
ENSG00000101546homo_sapiensENSP0000030569663.556952.4781rhinolophus_ferrumequinumENSRFEP0001002999361.931851.1364
ENSG00000101546homo_sapiensENSP0000030569656.268246.3557neovison_visonENSNVIP0000001391569.927557.6087
ENSG00000101546homo_sapiensENSP0000030569665.306157.1429bos_taurusENSBTAP0000004745076.712367.1233
ENSG00000101546homo_sapiensENSP0000030569692.419888.3382rhinopithecus_bietiENSRBIP0000003041892.419888.3382
ENSG00000101546homo_sapiensENSP0000030569667.346955.3936canis_lupus_dingoENSCAFP0002001832170.426857.9268
ENSG00000101546homo_sapiensENSP0000030569667.346958.0175sciurus_vulgarisENSSVLP0000501612569.161759.5808
ENSG00000101546homo_sapiensENSP0000030569651.603546.6472procavia_capensisENSPCAP0000000908981.566873.7327
ENSG00000101546homo_sapiensENSP0000030569669.387860.3499nannospalax_galiliENSNGAP0000000887972.121262.7273
ENSG00000101546homo_sapiensENSP0000030569665.306156.8513bos_grunniensENSBGRP0000003923249.777843.3333
ENSG00000101546homo_sapiensENSP0000030569669.387860.0583chinchilla_lanigeraENSCLAP0000001767969.794760.4106
ENSG00000101546homo_sapiensENSP0000030569664.431555.102cervus_hanglu_yarkandensisENSCHYP0000003918675.684964.726
ENSG00000101546homo_sapiensENSP0000030569669.679361.2245catagonus_wagneriENSCWAP0000000096473.538564.6154
ENSG00000101546homo_sapiensENSP0000030569670.553959.7668ictidomys_tridecemlineatusENSSTOP0000000925370.553959.7668
ENSG00000101546homo_sapiensENSP0000030569675.801867.3469otolemur_garnettiiENSOGAP0000001135876.923168.3432
ENSG00000101546homo_sapiensENSP0000030569688.921385.1312cebus_imitatorENSCCAP0000001497888.921385.1312
ENSG00000101546homo_sapiensENSP0000030569670.553959.4752urocitellus_parryiiENSUPAP0001000119370.553959.4752
ENSG00000101546homo_sapiensENSP0000030569663.848455.9767moschus_moschiferusENSMMSP000000090767565.7534
ENSG00000101546homo_sapiensENSP0000030569692.128388.3382rhinopithecus_roxellanaENSRROP0000001205892.128388.3382
ENSG00000101546homo_sapiensENSP0000030569672.011761.516mus_pahariMGP_PahariEiJ_P003978171.594261.1594
ENSG00000101546homo_sapiensENSP0000030569676.676467.6385propithecus_coquereliENSPCOP0000000849078.273869.0476
ENSG00000101546homo_sapiensENSP0000030569627.113712.5364caenorhabditis_elegansC25G4.3a.140.969218.9427
ENSG00000101546homo_sapiensENSP0000030569626.822216.9096drosophila_melanogasterFBpp007392733.948321.4022
ENSG00000101546homo_sapiensENSP0000030569631.195316.3265ciona_intestinalisENSCINP0000002007436.643819.1781
ENSG00000101546homo_sapiensENSP0000030569642.565624.7813eptatretus_burgeriENSEBUP0000001683939.78223.1608
ENSG00000101546homo_sapiensENSP0000030569650.145834.1108callorhinchus_miliiENSCMIP0000002731556.393438.3607
ENSG00000101546homo_sapiensENSP0000030569646.647230.0292latimeria_chalumnaeENSLACP0000000362148.632231.307
ENSG00000101546homo_sapiensENSP0000030569655.393637.3178lepisosteus_oculatusENSLOCP0000001022046.454831.2958
ENSG00000101546homo_sapiensENSP0000030569645.48130.0292clupea_harengusENSCHAP0000001482256.317737.1841
ENSG00000101546homo_sapiensENSP0000030569646.355732.3615danio_rerioENSDARP0000011403845.299131.6239
ENSG00000101546homo_sapiensENSP0000030569642.857127.9883carassius_auratusENSCARP0000010693653.649635.0365
ENSG00000101546homo_sapiensENSP0000030569648.979630.6122astyanax_mexicanusENSAMXP0000004139646.927429.3296
ENSG00000101546homo_sapiensENSP0000030569648.979630.0292ictalurus_punctatusENSIPUP0000000313248.554929.7688
ENSG00000101546homo_sapiensENSP0000030569650.145833.2362esox_luciusENSELUP0000004792845.263230
ENSG00000101546homo_sapiensENSP0000030569650.437331.4869electrophorus_electricusENSEEEP0000003414550.733131.6716
ENSG00000101546homo_sapiensENSP0000030569650.145832.9446oncorhynchus_kisutchENSOKIP0000510232148.450731.831
ENSG00000101546homo_sapiensENSP0000030569650.728933.2362oncorhynchus_kisutchENSOKIP0000508411248.876432.0225
ENSG00000101546homo_sapiensENSP0000030569650.437332.9446oncorhynchus_mykissENSOMYP0000000039748.595531.7416
ENSG00000101546homo_sapiensENSP0000030569645.772629.1545salmo_salarENSSSAP0000013144946.449729.5858
ENSG00000101546homo_sapiensENSP0000030569649.562732.6531salmo_salarENSSSAP0000013559347.887331.5493
ENSG00000101546homo_sapiensENSP0000030569649.562732.3615salmo_truttaENSSTUP0000007854547.887331.2676
ENSG00000101546homo_sapiensENSP0000030569649.271132.07salmo_truttaENSSTUP0000008013345.066729.3333
ENSG00000101546homo_sapiensENSP0000030569646.938830.9038gadus_morhuaENSGMOP0000003762845.609130.0283
ENSG00000101546homo_sapiensENSP0000030569655.10238.484xenopus_tropicalisENSXETP0000006229753.089937.0787
ENSG00000101546homo_sapiensENSP0000030569660.058345.1895chrysemys_picta_belliiENSCPBP0000000821952.020239.1414
ENSG00000101546homo_sapiensENSP0000030569625.947520.6997sphenodon_punctatusENSSPUP0000000898857.792246.1039
ENSG00000101546homo_sapiensENSP0000030569639.941726.2391crocodylus_porosusENSCPRP0000500617543.910328.8462
ENSG00000101546homo_sapiensENSP0000030569654.810537.6093laticauda_laticaudataENSLLTP0000000343445.410631.1594
ENSG00000101546homo_sapiensENSP0000030569648.68832.9446notechis_scutatusENSNSUP0000002305752.515735.5346
ENSG00000101546homo_sapiensENSP0000030569654.810538.1924pseudonaja_textilisENSPTXP0000000075853.868237.5358
ENSG00000101546homo_sapiensENSP0000030569655.685138.7755anas_platyrhynchos_platyrhynchosENSAPLP0000001535144.21330.787
ENSG00000101546homo_sapiensENSP0000030569652.478134.6939gallus_gallusENSGALP0001001076055.727636.8421
ENSG00000101546homo_sapiensENSP0000030569653.352836.1516serinus_canariaENSSCAP0000002195753.197736.0465
ENSG00000101546homo_sapiensENSP0000030569642.565627.9883parus_majorENSPMJP0000002473633.640622.1198
ENSG00000101546homo_sapiensENSP0000030569652.769738.1924anolis_carolinensisENSACAP0000000123948.395735.0267
ENSG00000101546homo_sapiensENSP0000030569655.393638.7755naja_najaENSNNAP0000002306354.131137.8917
ENSG00000101546homo_sapiensENSP0000030569653.935940.8163podarcis_muralisENSPMRP0000000895041.38731.3199
ENSG00000101546homo_sapiensENSP0000030569654.51937.3178geospiza_fortisENSGFOP0000002005356.666738.7879
ENSG00000101546homo_sapiensENSP0000030569654.810536.7347taeniopygia_guttataENSTGUP0000000686356.969738.1818
ENSG00000101546homo_sapiensENSP0000030569653.935933.5277erpetoichthys_calabaricusENSECRP0000002870651.246531.856
ENSG00000101546homo_sapiensENSP0000030569646.064132.3615salvator_merianaeENSSMRP0000000579155.438638.9474
ENSG00000101546homo_sapiensENSP0000030569658.600643.7318pelodiscus_sinensisENSPSIP0000000556855.068541.0959
ENSG00000101546homo_sapiensENSP0000030569653.352836.7347gopherus_evgoodeiENSGEVP0000501262756.13538.6503
ENSG00000101546homo_sapiensENSP0000030569647.230335.277chelonoidis_abingdoniiENSCABP0000000302665.060248.5944
ENSG00000101546homo_sapiensENSP0000030569653.352836.1516struthio_camelus_australisENSSCUP0000001825751.988635.2273
ENSG00000101546homo_sapiensENSP0000030569654.227437.0262anser_brachyrhynchusENSABRP0000001121855.357137.7976
ENSG00000101546homo_sapiensENSP0000030569654.227436.1516strigops_habroptilaENSSHBP0000500520354.705936.4706
ENSG00000101546homo_sapiensENSP0000030569650.145835.8601terrapene_carolina_triunguisENSTMTP0000000187559.930342.8571
ENSG00000101546homo_sapiensENSP0000030569649.854231.7784hucho_huchoENSHHUP0000003532647.530.2778
ENSG00000101546homo_sapiensENSP0000030569649.562731.1953pygocentrus_nattereriENSPNAP0000003633146.321529.1553
ENSG00000101546homo_sapiensENSP0000030569646.064129.1545oncorhynchus_tshawytschaENSOTSP0000500991552.666733.3333
ENSG00000101546homo_sapiensENSP0000030569655.685138.7755aquila_chrysaetos_chrysaetosENSACCP0002001745357.878840.303
ENSG00000101546homo_sapiensENSP0000030569648.979632.07denticeps_clupeoidesENSDCDP0000002411148.41531.7003
ENSG00000101546homo_sapiensENSP0000030569654.227437.3178ficedula_albicollisENSFALP0000001388756.53538.9058
ENSG00000101546homo_sapiensENSP0000030569648.979633.2362cyprinus_carpio_carpioENSCCRP0000008984147.592132.2946
ENSG00000101546homo_sapiensENSP0000030569652.769735.5685coturnix_japonicaENSCJPP0000502259558.012839.1026
ENSG00000101546homo_sapiensENSP0000030569632.653121.8659sinocyclocheilus_grahamiENSSGRP0000009959549.339233.0396
ENSG00000101546homo_sapiensENSP0000030569651.31230.6122paramormyrops_kingsleyaeENSPKIP0000000408248.484828.9256
ENSG00000101546homo_sapiensENSP0000030569652.186632.6531scleropages_formosusENSSFOP0001500052848.907130.6011
ENSG00000101546homo_sapiensENSP0000030569653.061239.0671leptobrachium_leishanenseENSLLEP0000001423551.267637.7465

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003674enables molecular_function1NDHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005575is_active_in cellular_component1NDHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IEAHomo_sapiens(9606)Component
GO:0006364involved_in rRNA processing1IEAHomo_sapiens(9606)Process
GO:0008150involved_in biological_process1NDHomo_sapiens(9606)Process

Expression