RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	ncRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000100697	Gene ID	23405	Accession	17098
Symbol	DICER1	Alias	DCR1;GLOW;MNG1;aviD;Dicer;HERNA;RMSE2;Dicer1e;K12H4.8-LIKE	Full Name	dicer 1, ribonuclease III
Status	Confidence	Length	71783 bases	Strand	Minus strand
Position	14 : 95086228 - 95158010	RNA binding domain	ResIII , DEAD , Ribonucleas_3_3 , PAZ , Dicer_dimer , Ribonuclease_3
Summary	This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2021]