RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000100505	Gene ID	114088	Accession	16288
Symbol	TRIM9	Alias	RNF91;SPRING	Full Name	tripartite motif containing 9
Status	Confidence	Length	120800 bases	Strand	Minus strand
Position	14 : 50975262 - 51096061	RNA binding domain	SPRY
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000298355	SPRY	PF00622	1.2e-12	1
ENSP00000507131	SPRY	PF00622	1.4e-12	1
ENSP00000342970	SPRY	PF00622	2.7e-12	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
TRIM9-201	ENST00000298355	5284	710aa	ENSP00000298355
TRIM9-202	ENST00000338969	3312	802aa	ENSP00000342970
TRIM9-204	ENST00000555170	554	No protein	-
TRIM9-206	ENST00000557456	550	No protein	-
TRIM9-205	ENST00000555933	640	No protein	-
TRIM9-203	ENST00000360392	3726	550aa	ENSP00000353561
TRIM9-207	ENST00000684578	4579	795aa	ENSP00000507131

Gene Model

Click here to download ENSG00000100505's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
11253	Bone Density	1.40442538270459E-5	17903296
25622	Coronary Artery Disease	3.5810000E-005	-
41374	Platelet Function Tests	2.1752900E-005	-
75793	Uric Acid	9E-6	25811787
75794	Body Mass Index	9E-6	25811787
85664	Cyclophosphamide	7E-6	26980576
85665	Lupus Erythematosus, Systemic	7E-6	26980576
85666	Lupus Nephritis	7E-6	26980576
94335	Psychotic Disorders	8E-7	24132900

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000100505's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005856	located_in cytoskeleton	1	IEA	Homo_sapiens(9606)	Component
GO:0008021	located_in synaptic vesicle	1	IEA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0016567	involved_in protein ubiquitination	1	IEA	Homo_sapiens(9606)	Process
GO:0019904	enables protein domain specific binding	1	IPI	Homo_sapiens(9606)	Function
GO:0030425	located_in dendrite	1	IDA	Homo_sapiens(9606)	Component
GO:0042803	enables protein homodimerization activity	1	IPI	Homo_sapiens(9606)	Function
GO:0043161	involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IDA	Homo_sapiens(9606)	Function

Expression