RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2DengueZika
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000100030	Gene ID	5594	Accession	6871
Symbol	MAPK1	Alias	ERK;p38;p40;p41;ERK2;ERT1;NS13;ERK-2;MAPK2;PRKM1;PRKM2;P42MAPK;p41mapk;p42-MAPK	Full Name	mitogen-activated protein kinase 1
Status	Confidence	Length	108024 bases	Strand	Minus strand
Position	22 : 21759657 - 21867680	RNA binding domain	N.A.
Summary	This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
MAPK1-201	ENST00000215832	5881	360aa	ENSP00000215832
MAPK1-203	ENST00000491588	491	No protein	-
MAPK1-202	ENST00000398822	1487	360aa	ENSP00000381803
MAPK1-204	ENST00000544786	951	316aa	ENSP00000440842

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
27504	Cardiovascular Physiological Phenomena	1.2150000E-005	-
100307	Multiple Sclerosis	5E-9	21833088

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000100030	homo_sapiens	ENSP00000215659	55.3134	37.6022	homo_sapiens	ENSP00000215832	56.3889	38.3333
ENSG00000100030	homo_sapiens	ENSP00000378968	29.5343	21.201	homo_sapiens	ENSP00000215832	66.9444	48.0556
ENSG00000100030	homo_sapiens	ENSP00000333685	57.4176	40.3846	homo_sapiens	ENSP00000215832	58.0556	40.8333
ENSG00000100030	homo_sapiens	ENSP00000346484	27.0062	17.4383	homo_sapiens	ENSP00000215832	48.6111	31.3889
ENSG00000100030	homo_sapiens	ENSP00000501692	27.5316	18.6709	homo_sapiens	ENSP00000215832	48.3333	32.7778
ENSG00000100030	homo_sapiens	ENSP00000261845	29.5423	20.111	homo_sapiens	ENSP00000215832	59.1667	40.2778
ENSG00000100030	homo_sapiens	ENSP00000377262	21.03	13.1617	homo_sapiens	ENSP00000215832	40.8333	25.5556
ENSG00000100030	homo_sapiens	ENSP00000337691	37.3162	26.6544	homo_sapiens	ENSP00000215832	56.3889	40.2778
ENSG00000100030	homo_sapiens	ENSP00000355304	37.9475	23.8663	homo_sapiens	ENSP00000215832	44.1667	27.7778
ENSG00000100030	homo_sapiens	ENSP00000384625	41.3662	27.8937	homo_sapiens	ENSP00000215832	60.5556	40.8333
ENSG00000100030	homo_sapiens	ENSP00000383234	35.7751	23.8501	homo_sapiens	ENSP00000215832	58.3333	38.8889
ENSG00000100030	homo_sapiens	ENSP00000363304	49.6487	32.7869	homo_sapiens	ENSP00000215832	58.8889	38.8889
ENSG00000100030	homo_sapiens	ENSP00000493435	45.6897	30.6034	homo_sapiens	ENSP00000215832	58.8889	39.4444
ENSG00000100030	homo_sapiens	ENSP00000263025	88.1266	82.3219	homo_sapiens	ENSP00000215832	92.7778	86.6667
ENSG00000100030	homo_sapiens	ENSP00000229794	61.1111	43.8889	homo_sapiens	ENSP00000215832	61.1111	43.8889
ENSG00000100030	homo_sapiens	ENSP00000362931	22.1374	14.1985	homo_sapiens	ENSP00000215832	40.2778	25.8333
ENSG00000100030	homo_sapiens	ENSP00000211287	55.6164	38.9041	homo_sapiens	ENSP00000215832	56.3889	39.4444
ENSG00000100030	homo_sapiens	ENSP00000359119	24.8677	15.3439	homo_sapiens	ENSP00000215832	39.1667	24.1667
ENSG00000100030	homo_sapiens	ENSP00000394560	48.8208	32.0755	homo_sapiens	ENSP00000215832	57.5	37.7778

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000100030	homo_sapiens	ENSP00000215832	94.7222	94.7222	nomascus_leucogenys	ENSNLEP00000027273	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	90.2778	89.7222	pan_paniscus	ENSPPAP00000006243	95.8702	95.2802
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.7222	pongo_abelii	ENSPPYP00000023664	98.8981	98.8981
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	pan_troglodytes	ENSPTRP00000024313	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	98.0556	97.7778	gorilla_gorilla	ENSGGOP00000040522	93.1398	92.876
ENSG00000100030	homo_sapiens	ENSP00000215832	86.3889	81.6667	ornithorhynchus_anatinus	ENSOANP00000043143	74.0476	70
ENSG00000100030	homo_sapiens	ENSP00000215832	91.1111	88.8889	sarcophilus_harrisii	ENSSHAP00000032133	94.2529	91.954
ENSG00000100030	homo_sapiens	ENSP00000215832	60.5556	60.2778	notamacropus_eugenii	ENSMEUP00000003820	60.7242	60.4457
ENSG00000100030	homo_sapiens	ENSP00000215832	78.0556	77.7778	choloepus_hoffmanni	ENSCHOP00000008916	87.8125	87.5
ENSG00000100030	homo_sapiens	ENSP00000215832	82.2222	80.5556	dasypus_novemcinctus	ENSDNOP00000007040	90.7975	88.9571
ENSG00000100030	homo_sapiens	ENSP00000215832	84.7222	81.9444	dasypus_novemcinctus	ENSDNOP00000035147	96.519	93.3544
ENSG00000100030	homo_sapiens	ENSP00000215832	73.6111	73.6111	erinaceus_europaeus	ENSEEUP00000002310	74.0223	74.0223
ENSG00000100030	homo_sapiens	ENSP00000215832	99.1667	98.8889	echinops_telfairi	ENSETEP00000009702	99.4429	99.1643
ENSG00000100030	homo_sapiens	ENSP00000215832	65.8333	62.2222	callithrix_jacchus	ENSCJAP00000090447	59.6977	56.4232
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	cercocebus_atys	ENSCATP00000015951	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	macaca_fascicularis	ENSMFAP00000004754	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	macaca_mulatta	ENSMMUP00000016444	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	95.2778	macaca_nemestrina	ENSMNEP00000011854	96.9014	96.6197
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	papio_anubis	ENSPANP00000025866	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	91.6667	90.8333	mandrillus_leucophaeus	ENSMLEP00000023677	96.2099	95.3353
ENSG00000100030	homo_sapiens	ENSP00000215832	88.8889	88.8889	tursiops_truncatus	ENSTTRP00000015859	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	92.7778	92.2222	vulpes_vulpes	ENSVVUP00000027843	85.2041	84.6939
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	mus_spretus	MGP_SPRETEiJ_P0042419	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	equus_asinus	ENSEASP00005032621	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	capra_hircus	ENSCHIP00000000204	90.9091	90.6566
ENSG00000100030	homo_sapiens	ENSP00000215832	88.3333	87.7778	loxodonta_africana	ENSLAFP00000008420	96.6565	96.0486
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.4444	panthera_leo	ENSPLOP00000017103	86.506	86.2651
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	90.8333	ailuropoda_melanoleuca	ENSAMEP00000030976	91.1846	90.0826
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.4444	bos_indicus_hybrid	ENSBIXP00005011080	56.6246	56.4669
ENSG00000100030	homo_sapiens	ENSP00000215832	90.8333	90	oryctolagus_cuniculus	ENSOCUP00000011783	89.8352	89.011
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	equus_caballus	ENSECAP00000084769	60.2694	60.2694
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	canis_lupus_familiaris	ENSCAFP00845036530	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.4444	panthera_pardus	ENSPPRP00000017574	100	99.4444
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	marmota_marmota_marmota	ENSMMMP00000000591	100	99.7222
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	balaenoptera_musculus	ENSBMSP00010020003	99.7215	99.7215
ENSG00000100030	homo_sapiens	ENSP00000215832	89.1667	88.6111	cavia_porcellus	ENSCPOP00000011740	98.7692	98.1538
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	felis_catus	ENSFCAP00000025541	51.5759	51.4327
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	90.2778	ursus_americanus	ENSUAMP00000013584	90.9341	89.2857
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	97.5	monodelphis_domestica	ENSMODP00000022098	98.0501	97.7716
ENSG00000100030	homo_sapiens	ENSP00000215832	90.5556	88.8889	monodelphis_domestica	ENSMODP00000018334	92.3513	90.6516
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	90.5556	bison_bison_bison	ENSBBBP00000028006	88.7399	87.3995
ENSG00000100030	homo_sapiens	ENSP00000215832	99.1667	99.1667	monodon_monoceros	ENSMMNP00015005638	99.7207	99.7207
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	sus_scrofa	ENSSSCP00000073842	63.0282	63.0282
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	microcebus_murinus	ENSMICP00000017583	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	98.8889	octodon_degus	ENSODEP00000021491	99.7215	99.1643
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.4444	jaculus_jaculus	ENSJJAP00000022529	99.7222	99.4444
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.4444	ovis_aries_rambouillet	ENSOARP00020033914	99.446	99.169
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	90.5556	ursus_maritimus	ENSUMAP00000004216	91.1846	89.8072
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	ochotona_princeps	ENSOPRP00000013218	99.7215	99.7215
ENSG00000100030	homo_sapiens	ENSP00000215832	99.1667	99.1667	delphinapterus_leucas	ENSDLEP00000021680	93.9474	93.9474
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	physeter_catodon	ENSPCTP00005019452	99.7215	99.7215
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	mus_caroli	MGP_CAROLIEiJ_P0040564	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	mus_musculus	ENSMUSP00000065983	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.4444	dipodomys_ordii	ENSDORP00000016925	100	99.4444
ENSG00000100030	homo_sapiens	ENSP00000215832	89.7222	89.1667	mustela_putorius_furo	ENSMPUP00000003112	96.997	96.3964
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.8889	aotus_nancymaae	ENSANAP00000014877	94.6809	94.6809
ENSG00000100030	homo_sapiens	ENSP00000215832	81.9444	81.3889	saimiri_boliviensis_boliviensis	ENSSBOP00000023855	96.7213	96.0656
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	chlorocebus_sabaeus	ENSCSAP00000009828	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	61.3889	61.1111	tupaia_belangeri	ENSTBEP00000007776	85.6589	85.2713
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	mesocricetus_auratus	ENSMAUP00000018564	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	phocoena_sinus	ENSPSNP00000018097	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	camelus_dromedarius	ENSCDRP00005032276	99.7215	99.7215
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.1667	carlito_syrichta	ENSTSYP00000032180	98.8981	98.3471
ENSG00000100030	homo_sapiens	ENSP00000215832	88.8889	88.6111	panthera_tigris_altaica	ENSPTIP00000004736	88.8889	88.6111
ENSG00000100030	homo_sapiens	ENSP00000215832	97.5	96.9444	rattus_norvegicus	ENSRNOP00000086878	94.3548	93.8172
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	prolemur_simus	ENSPSMP00000020060	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	98.6111	98.3333	microtus_ochrogaster	ENSMOCP00000012005	99.4398	99.1597
ENSG00000100030	homo_sapiens	ENSP00000215832	62.5	62.2222	sorex_araneus	ENSSARP00000013061	79.7872	79.4326
ENSG00000100030	homo_sapiens	ENSP00000215832	98.6111	98.3333	peromyscus_maniculatus_bairdii	ENSPEMP00000012990	99.4398	99.1597
ENSG00000100030	homo_sapiens	ENSP00000215832	90.5556	89.7222	bos_mutus	ENSBMUP00000003546	98.1928	97.2892
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	mus_spicilegus	ENSMSIP00000020806	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	cricetulus_griseus_chok1gshd	ENSCGRP00001022860	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	88.6111	88.6111	pteropus_vampyrus	ENSPVAP00000012866	88.8579	88.8579
ENSG00000100030	homo_sapiens	ENSP00000215832	88.8889	88.8889	myotis_lucifugus	ENSMLUP00000005441	99.6885	99.6885
ENSG00000100030	homo_sapiens	ENSP00000215832	93.3333	92.5	myotis_lucifugus	ENSMLUP00000022195	93.3333	92.5
ENSG00000100030	homo_sapiens	ENSP00000215832	96.1111	95.8333	vombatus_ursinus	ENSVURP00010028502	99.1404	98.8539
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	rhinolophus_ferrumequinum	ENSRFEP00010026783	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	neovison_vison	ENSNVIP00000027883	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	bos_taurus	ENSBTAP00000013623	100	99.7222
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	heterocephalus_glaber_female	ENSHGLP00000029496	100	99.7222
ENSG00000100030	homo_sapiens	ENSP00000215832	95	95	rhinopithecus_bieti	ENSRBIP00000026426	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	96.6667	96.6667	canis_lupus_dingo	ENSCAFP00020019010	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	sciurus_vulgaris	ENSSVLP00005008763	100	99.7222
ENSG00000100030	homo_sapiens	ENSP00000215832	84.1667	80.8333	phascolarctos_cinereus	ENSPCIP00000035808	85.8357	82.4363
ENSG00000100030	homo_sapiens	ENSP00000215832	81.3889	81.3889	procavia_capensis	ENSPCAP00000009794	81.6156	81.6156
ENSG00000100030	homo_sapiens	ENSP00000215832	98.6111	98.3333	nannospalax_galili	ENSNGAP00000016309	98.6111	98.3333
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.4444	bos_grunniens	ENSBGRP00000039366	56.5354	56.378
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	chinchilla_lanigera	ENSCLAP00000024734	100	99.7222
ENSG00000100030	homo_sapiens	ENSP00000215832	83.0556	81.6667	cervus_hanglu_yarkandensis	ENSCHYP00000009688	73.8272	72.5926
ENSG00000100030	homo_sapiens	ENSP00000215832	99.4444	99.4444	catagonus_wagneri	ENSCWAP00000008234	99.7215	99.7215
ENSG00000100030	homo_sapiens	ENSP00000215832	90.2778	89.1667	ictidomys_tridecemlineatus	ENSSTOP00000013254	98.1873	96.9789
ENSG00000100030	homo_sapiens	ENSP00000215832	88.6111	88.6111	otolemur_garnettii	ENSOGAP00000008157	98.7616	98.7616
ENSG00000100030	homo_sapiens	ENSP00000215832	97.5	97.2222	cebus_imitator	ENSCCAP00000014631	95.9016	95.6284
ENSG00000100030	homo_sapiens	ENSP00000215832	100	99.7222	urocitellus_parryii	ENSUPAP00010017096	100	99.7222
ENSG00000100030	homo_sapiens	ENSP00000215832	99.7222	99.4444	moschus_moschiferus	ENSMMSP00000021811	99.1713	98.895
ENSG00000100030	homo_sapiens	ENSP00000215832	89.7222	88.8889	rhinopithecus_roxellana	ENSRROP00000024767	97.8788	96.9697
ENSG00000100030	homo_sapiens	ENSP00000215832	98.8889	98.6111	mus_pahari	MGP_PahariEiJ_P0027958	99.4413	99.162
ENSG00000100030	homo_sapiens	ENSP00000215832	100	100	propithecus_coquereli	ENSPCOP00000029858	100	100
ENSG00000100030	homo_sapiens	ENSP00000215832	85	77.2222	caenorhabditis_elegans	F43C1.2b.1	68.9189	62.6126
ENSG00000100030	homo_sapiens	ENSP00000215832	86.6667	78.6111	drosophila_melanogaster	FBpp0311493	82.9787	75.266
ENSG00000100030	homo_sapiens	ENSP00000215832	87.5	80.5556	ciona_intestinalis	ENSCINP00000014552	90	82.8571
ENSG00000100030	homo_sapiens	ENSP00000215832	94.4444	89.1667	petromyzon_marinus	ENSPMAP00000010177	91.3979	86.2903
ENSG00000100030	homo_sapiens	ENSP00000215832	68.3333	64.7222	eptatretus_burgeri	ENSEBUP00000017381	92.8302	87.9245
ENSG00000100030	homo_sapiens	ENSP00000215832	94.7222	91.6667	callorhinchus_milii	ENSCMIP00000032576	87.6607	84.8329
ENSG00000100030	homo_sapiens	ENSP00000215832	96.6667	93.3333	latimeria_chalumnae	ENSLACP00000015867	95.3425	92.0548
ENSG00000100030	homo_sapiens	ENSP00000215832	96.3889	93.3333	lepisosteus_oculatus	ENSLOCP00000002360	94.0379	91.0569
ENSG00000100030	homo_sapiens	ENSP00000215832	95	90.5556	clupea_harengus	ENSCHAP00000058109	87.9177	83.8046
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.7778	danio_rerio	ENSDARP00000038550	93.2249	90.5149
ENSG00000100030	homo_sapiens	ENSP00000215832	94.7222	92.2222	carassius_auratus	ENSCARP00000037792	87.4359	85.1282
ENSG00000100030	homo_sapiens	ENSP00000215832	95	91.6667	carassius_auratus	ENSCARP00000124448	87.9177	84.8329
ENSG00000100030	homo_sapiens	ENSP00000215832	88.8889	84.7222	astyanax_mexicanus	ENSAMXP00000001246	78.0488	74.3902
ENSG00000100030	homo_sapiens	ENSP00000215832	95	92.7778	ictalurus_punctatus	ENSIPUP00000030101	91.2	89.0667
ENSG00000100030	homo_sapiens	ENSP00000215832	93.8889	90.5556	esox_lucius	ENSELUP00000069352	88.7139	85.5643
ENSG00000100030	homo_sapiens	ENSP00000215832	95.2778	92.2222	electrophorus_electricus	ENSEEEP00000018510	88.8601	86.0104
ENSG00000100030	homo_sapiens	ENSP00000215832	67.7778	57.5	oncorhynchus_kisutch	ENSOKIP00005028637	35.2601	29.9133
ENSG00000100030	homo_sapiens	ENSP00000215832	93.6111	90.8333	oncorhynchus_kisutch	ENSOKIP00005009666	91.3279	88.6179
ENSG00000100030	homo_sapiens	ENSP00000215832	93.6111	90.8333	oncorhynchus_mykiss	ENSOMYP00000129285	88.4514	85.8268
ENSG00000100030	homo_sapiens	ENSP00000215832	91.1111	88.6111	oncorhynchus_mykiss	ENSOMYP00000132444	89.6175	87.1585
ENSG00000100030	homo_sapiens	ENSP00000215832	93.8889	90.5556	salmo_salar	ENSSSAP00000130067	91.5989	88.3469
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	88.8889	salmo_salar	ENSSSAP00000162170	76.7981	74.2459
ENSG00000100030	homo_sapiens	ENSP00000215832	71.9444	69.4444	salmo_salar	ENSSSAP00000173949	93.8406	90.5797
ENSG00000100030	homo_sapiens	ENSP00000215832	86.9444	82.2222	salmo_trutta	ENSSTUP00000017302	55.2028	52.2046
ENSG00000100030	homo_sapiens	ENSP00000215832	93.6111	90.8333	salmo_trutta	ENSSTUP00000030531	89.6277	86.9681
ENSG00000100030	homo_sapiens	ENSP00000215832	95.2778	91.3889	gadus_morhua	ENSGMOP00000014982	88.4021	84.7938
ENSG00000100030	homo_sapiens	ENSP00000215832	95	91.9444	fundulus_heteroclitus	ENSFHEP00000011839	92.6829	89.7019
ENSG00000100030	homo_sapiens	ENSP00000215832	96.1111	92.5	poecilia_reticulata	ENSPREP00000019735	95.0549	91.4835
ENSG00000100030	homo_sapiens	ENSP00000215832	96.1111	92.5	xiphophorus_maculatus	ENSXMAP00000006468	95.0549	91.4835
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.5	oryzias_latipes	ENSORLP00000039541	93.2249	90.2439
ENSG00000100030	homo_sapiens	ENSP00000215832	88.0556	83.8889	cyclopterus_lumpus	ENSCLMP00005032781	76.57	72.9469
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.2222	oreochromis_niloticus	ENSONIP00000077238	93.4959	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.2222	haplochromis_burtoni	ENSHBUP00000024696	93.4959	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.2222	astatotilapia_calliptera	ENSACLP00000005434	93.4959	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	95.2778	91.6667	sparus_aurata	ENSSAUP00010010405	90.5013	87.0712
ENSG00000100030	homo_sapiens	ENSP00000215832	86.6667	82.7778	lates_calcarifer	ENSLCAP00010051733	82.1053	78.4211
ENSG00000100030	homo_sapiens	ENSP00000215832	96.9444	95.5556	xenopus_tropicalis	ENSXETP00000079571	96.6759	95.2909
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	96.9444	chrysemys_picta_bellii	ENSCPBP00000014183	95.6522	94.837
ENSG00000100030	homo_sapiens	ENSP00000215832	98.0556	96.6667	sphenodon_punctatus	ENSSPUP00000020365	95.9239	94.5652
ENSG00000100030	homo_sapiens	ENSP00000215832	75.5556	73.0556	crocodylus_porosus	ENSCPRP00005000848	91.2752	88.255
ENSG00000100030	homo_sapiens	ENSP00000215832	97.5	94.7222	laticauda_laticaudata	ENSLLTP00000008424	95.3804	92.663
ENSG00000100030	homo_sapiens	ENSP00000215832	96.9444	94.4444	notechis_scutatus	ENSNSUP00000012703	95.6164	93.1507
ENSG00000100030	homo_sapiens	ENSP00000215832	97.2222	94.4444	pseudonaja_textilis	ENSPTXP00000011774	95.1087	92.3913
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	97.2222	anas_platyrhynchos_platyrhynchos	ENSAPLP00000005723	95.6522	95.1087
ENSG00000100030	homo_sapiens	ENSP00000215832	93.8889	90.8333	gallus_gallus	ENSGALP00010036277	80.285	77.6722
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	89.7222	meleagris_gallopavo	ENSMGAP00000000469	88.2667	86.1333
ENSG00000100030	homo_sapiens	ENSP00000215832	96.3889	96.1111	serinus_canaria	ENSSCAP00000005913	99.7126	99.4253
ENSG00000100030	homo_sapiens	ENSP00000215832	98.3333	97.5	parus_major	ENSPMJP00000019015	76.7896	76.1388
ENSG00000100030	homo_sapiens	ENSP00000215832	97.2222	95	anolis_carolinensis	ENSACAP00000001346	95.1087	92.9348
ENSG00000100030	homo_sapiens	ENSP00000215832	78.8889	75	neolamprologus_brichardi	ENSNBRP00000023207	83.0409	78.9474
ENSG00000100030	homo_sapiens	ENSP00000215832	97.2222	94.7222	naja_naja	ENSNNAP00000017484	95.1087	92.663
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	95.5556	podarcis_muralis	ENSPMRP00000029862	95.6522	93.4783
ENSG00000100030	homo_sapiens	ENSP00000215832	89.7222	89.4444	geospiza_fortis	ENSGFOP00000000286	95.5621	95.2663
ENSG00000100030	homo_sapiens	ENSP00000215832	98.0556	96.9444	taeniopygia_guttata	ENSTGUP00000031436	95.664	94.5799
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	90.8333	erpetoichthys_calabaricus	ENSECRP00000029456	91.9786	87.4332
ENSG00000100030	homo_sapiens	ENSP00000215832	93.8889	90.2778	kryptolebias_marmoratus	ENSKMAP00000005892	91.5989	88.0759
ENSG00000100030	homo_sapiens	ENSP00000215832	96.1111	95	salvator_merianae	ENSSMRP00000012334	94.0217	92.9348
ENSG00000100030	homo_sapiens	ENSP00000215832	86.9444	83.8889	oryzias_javanicus	ENSOJAP00000002096	91.7889	88.563
ENSG00000100030	homo_sapiens	ENSP00000215832	84.1667	81.1111	amphilophus_citrinellus	ENSACIP00000007539	93.2308	89.8462
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	91.9444	dicentrarchus_labrax	ENSDLAP00005058881	88.6598	85.3093
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	amphiprion_percula	ENSAPEP00000026166	93.2249	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	43.6111	42.2222	oryzias_sinensis	ENSOSIP00000006215	96.9136	93.8272
ENSG00000100030	homo_sapiens	ENSP00000215832	88.6111	87.2222	pelodiscus_sinensis	ENSPSIP00000003362	99.0683	97.5155
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	96.9444	gopherus_evgoodei	ENSGEVP00005014698	84.0095	83.2936
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	96.6667	chelonoidis_abingdonii	ENSCABP00000028265	94.37	93.2976
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	seriola_dumerili	ENSSDUP00000013074	93.2249	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	95	91.1111	cottoperca_gobio	ENSCGOP00000056359	87.6923	84.1026
ENSG00000100030	homo_sapiens	ENSP00000215832	84.7222	82.2222	struthio_camelus_australis	ENSSCUP00000005553	82.2102	79.7844
ENSG00000100030	homo_sapiens	ENSP00000215832	89.4444	88.6111	anser_brachyrhynchus	ENSABRP00000016589	96.4072	95.509
ENSG00000100030	homo_sapiens	ENSP00000215832	94.7222	91.1111	gasterosteus_aculeatus	ENSGACP00000019049	92.4119	88.8889
ENSG00000100030	homo_sapiens	ENSP00000215832	92.7778	88.6111	cynoglossus_semilaevis	ENSCSEP00000029876	93.2961	89.1061
ENSG00000100030	homo_sapiens	ENSP00000215832	34.4444	30	cynoglossus_semilaevis	ENSCSEP00000011950	72.093	62.7907
ENSG00000100030	homo_sapiens	ENSP00000215832	96.3889	92.7778	poecilia_formosa	ENSPFOP00000006223	95.3297	91.7582
ENSG00000100030	homo_sapiens	ENSP00000215832	40.5556	37.7778	myripristis_murdjan	ENSMMDP00005009187	96.6887	90.0662
ENSG00000100030	homo_sapiens	ENSP00000215832	95.2778	91.9444	sander_lucioperca	ENSSLUP00000036965	87.2774	84.2239
ENSG00000100030	homo_sapiens	ENSP00000215832	98.0556	96.9444	strigops_habroptila	ENSSHBP00005010516	95.9239	94.837
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	amphiprion_ocellaris	ENSAOCP00000001430	93.2249	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	97.2222	96.3889	terrapene_carolina_triunguis	ENSTMTP00000009038	95.6284	94.8087
ENSG00000100030	homo_sapiens	ENSP00000215832	20.2778	19.4444	hucho_hucho	ENSHHUP00000006905	96.0526	92.1053
ENSG00000100030	homo_sapiens	ENSP00000215832	62.7778	56.6667	hucho_hucho	ENSHHUP00000028574	76.8708	69.3878
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.5	betta_splendens	ENSBSLP00000041845	89.3506	86.4935
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.7778	pygocentrus_nattereri	ENSPNAP00000032622	92.9919	90.027
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	anabas_testudineus	ENSATEP00000058109	87.9795	84.9105
ENSG00000100030	homo_sapiens	ENSP00000215832	86.9444	80.8333	ciona_savignyi	ENSCSAVP00000014424	89.4286	83.1429
ENSG00000100030	homo_sapiens	ENSP00000215832	60	40.2778	saccharomyces_cerevisiae	YKL161C	49.8845	33.4873
ENSG00000100030	homo_sapiens	ENSP00000215832	65	46.6667	saccharomyces_cerevisiae	YHR030C	48.3471	34.7107
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	seriola_lalandi_dorsalis	ENSSLDP00000033321	93.2249	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	94.7222	90.8333	labrus_bergylta	ENSLBEP00000023541	91.9137	88.1402
ENSG00000100030	homo_sapiens	ENSP00000215832	85.8333	81.6667	pundamilia_nyererei	ENSPNYP00000007060	92.515	88.0239
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	mastacembelus_armatus	ENSMAMP00000023547	87.3096	84.264
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	stegastes_partitus	ENSSPAP00000031074	93.2249	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	74.4444	70.2778	oncorhynchus_tshawytscha	ENSOTSP00005053383	81.7073	77.1341
ENSG00000100030	homo_sapiens	ENSP00000215832	35.8333	34.1667	acanthochromis_polyacanthus	ENSAPOP00000027566	86	82
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	acanthochromis_polyacanthus	ENSAPOP00000010041	93.2249	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	80.2778	76.9444	acanthochromis_polyacanthus	ENSAPOP00000028293	92.3323	88.4984
ENSG00000100030	homo_sapiens	ENSP00000215832	98.0556	97.5	aquila_chrysaetos_chrysaetos	ENSACCP00020005442	95.9239	95.3804
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.5	nothobranchius_furzeri	ENSNFUP00015011993	88.9175	85.8247
ENSG00000100030	homo_sapiens	ENSP00000215832	90.2778	86.1111	cyprinodon_variegatus	ENSCVAP00000015363	92.5926	88.3191
ENSG00000100030	homo_sapiens	ENSP00000215832	95	90.5556	denticeps_clupeoides	ENSDCDP00000049874	88.601	84.456
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	larimichthys_crocea	ENSLCRP00005016597	87.5318	84.4784
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	takifugu_rubripes	ENSTRUP00000051554	88.2051	85.1282
ENSG00000100030	homo_sapiens	ENSP00000215832	91.9444	89.7222	ficedula_albicollis	ENSFALP00000008282	83.7975	81.7721
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	91.9444	hippocampus_comes	ENSHCOP00000021531	93.4783	89.9457
ENSG00000100030	homo_sapiens	ENSP00000215832	95.2778	92.2222	cyprinus_carpio_carpio	ENSCCRP00000000238	83.8631	81.1736
ENSG00000100030	homo_sapiens	ENSP00000215832	95	92.7778	cyprinus_carpio_carpio	ENSCCRP00000046771	88.1443	86.0825
ENSG00000100030	homo_sapiens	ENSP00000215832	97.7778	97.2222	coturnix_japonica	ENSCJPP00005024064	95.6522	95.1087
ENSG00000100030	homo_sapiens	ENSP00000215832	96.3889	93.0556	poecilia_latipinna	ENSPLAP00000016708	95.3297	92.033
ENSG00000100030	homo_sapiens	ENSP00000215832	94.7222	91.9444	sinocyclocheilus_grahami	ENSSGRP00000074851	87.8866	85.3093
ENSG00000100030	homo_sapiens	ENSP00000215832	95	92.7778	sinocyclocheilus_grahami	ENSSGRP00000087334	88.8312	86.7533
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.2222	maylandia_zebra	ENSMZEP00005027661	93.4959	89.9729
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	91.6667	tetraodon_nigroviridis	ENSTNIP00000018415	94.0054	89.9183
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	90.8333	paramormyrops_kingsleyae	ENSPKIP00000033096	93.2249	88.6179
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	scleropages_formosus	ENSSFOP00015047026	85.1485	82.1782
ENSG00000100030	homo_sapiens	ENSP00000215832	90.8333	89.1667	leptobrachium_leishanense	ENSLLEP00000014533	81.1414	79.6526
ENSG00000100030	homo_sapiens	ENSP00000215832	95.5556	92.2222	scophthalmus_maximus	ENSSMAP00000037872	79.4457	76.6744
ENSG00000100030	homo_sapiens	ENSP00000215832	95.8333	92.7778	oryzias_melastigma	ENSOMEP00000008061	93.4959	90.5149

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001784	enables phosphotyrosine residue binding	1	IEA	Homo_sapiens(9606)	Function
GO:0003677	enables DNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0004674	enables protein serine/threonine kinase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0004707	enables MAP kinase activity	1	TAS	Homo_sapiens(9606)	Function
GO:0004708	enables MAP kinase kinase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	TAS	Homo_sapiens(9606)	Component
GO:0005634	located_in nucleus	4	HDA,IBA,IDA,TAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	4	HDA,IBA,IDA,ISS	Homo_sapiens(9606)	Component
GO:0005739	located_in mitochondrion	1	TAS	Homo_sapiens(9606)	Component
GO:0005769	located_in early endosome	1	TAS	Homo_sapiens(9606)	Component
GO:0005770	located_in late endosome	1	TAS	Homo_sapiens(9606)	Component
GO:0005788	located_in endoplasmic reticulum lumen	1	TAS	Homo_sapiens(9606)	Component
GO:0005794	located_in Golgi apparatus	1	TAS	Homo_sapiens(9606)	Component
GO:0005815	located_in microtubule organizing center	1	IEA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0005856	located_in cytoskeleton	1	TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	ISS	Homo_sapiens(9606)	Component
GO:0005901	located_in caveola	2	ISS,TAS	Homo_sapiens(9606)	Component
GO:0005925	located_in focal adhesion	1	TAS	Homo_sapiens(9606)	Component
GO:0006357	involved_in regulation of transcription by RNA polymerase II	1	IEA	Homo_sapiens(9606)	Process
GO:0006468	involved_in protein phosphorylation	2	IDA,TAS	Homo_sapiens(9606)	Process
GO:0006915	involved_in apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006935	involved_in chemotaxis	1	TAS	Homo_sapiens(9606)	Process
GO:0006974	involved_in DNA damage response	1	IEA	Homo_sapiens(9606)	Process
GO:0007049	involved_in cell cycle	1	IEA	Homo_sapiens(9606)	Process
GO:0007165	involved_in signal transduction	1	TAS	Homo_sapiens(9606)	Process
GO:0007166	involved_in cell surface receptor signaling pathway	1	IBA	Homo_sapiens(9606)	Process
GO:0007268	involved_in chemical synaptic transmission	1	TAS	Homo_sapiens(9606)	Process
GO:0007611	involved_in learning or memory	1	NAS	Homo_sapiens(9606)	Process
GO:0008286	involved_in insulin receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0008353	enables RNA polymerase II CTD heptapeptide repeat kinase activity	1	ISS	Homo_sapiens(9606)	Function
GO:0010759	acts_upstream_of positive regulation of macrophage chemotaxis	1	IGI	Homo_sapiens(9606)	Process
GO:0010800	involved_in positive regulation of peptidyl-threonine phosphorylation	1	IDA	Homo_sapiens(9606)	Process
GO:0018105	involved_in peptidyl-serine phosphorylation	1	IDA	Homo_sapiens(9606)	Process
GO:0018107	involved_in peptidyl-threonine phosphorylation	1	ISS	Homo_sapiens(9606)	Process
GO:0019858	involved_in cytosine metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0019902	enables phosphatase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0030278	involved_in regulation of ossification	1	IEA	Homo_sapiens(9606)	Process
GO:0030521	involved_in androgen receptor signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:0030641	involved_in regulation of cellular pH	1	IEA	Homo_sapiens(9606)	Process
GO:0030878	involved_in thyroid gland development	1	IEA	Homo_sapiens(9606)	Process
GO:0031143	located_in pseudopodium	1	IEA	Homo_sapiens(9606)	Component
GO:0031647	involved_in regulation of protein stability	1	ISS	Homo_sapiens(9606)	Process
GO:0031663	involved_in lipopolysaccharide-mediated signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0032212	involved_in positive regulation of telomere maintenance via telomerase	1	IMP	Homo_sapiens(9606)	Process
GO:0032872	involved_in regulation of stress-activated MAPK cascade	1	TAS	Homo_sapiens(9606)	Process
GO:0033598	involved_in mammary gland epithelial cell proliferation	1	IEA	Homo_sapiens(9606)	Process
GO:0034198	involved_in cellular response to amino acid starvation	1	IDA	Homo_sapiens(9606)	Process
GO:0034614	involved_in cellular response to reactive oxygen species	1	IMP	Homo_sapiens(9606)	Process
GO:0035094	involved_in response to nicotine	1	ISS	Homo_sapiens(9606)	Process
GO:0035556	involved_in intracellular signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0035578	located_in azurophil granule lumen	1	TAS	Homo_sapiens(9606)	Component
GO:0038127	involved_in ERBB signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0042473	involved_in outer ear morphogenesis	1	IEA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0043330	involved_in response to exogenous dsRNA	1	IEA	Homo_sapiens(9606)	Process
GO:0043401	involved_in steroid hormone mediated signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:0045202	located_in synapse	1	IEA	Homo_sapiens(9606)	Component
GO:0045596	involved_in negative regulation of cell differentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0048009	involved_in insulin-like growth factor receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0048538	involved_in thymus development	1	IEA	Homo_sapiens(9606)	Process
GO:0050847	involved_in progesterone receptor signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:0050852	involved_in T cell receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0050853	involved_in B cell receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0051403	involved_in stress-activated MAPK cascade	1	IDA	Homo_sapiens(9606)	Process
GO:0051493	involved_in regulation of cytoskeleton organization	1	TAS	Homo_sapiens(9606)	Process
GO:0051973	involved_in positive regulation of telomerase activity	1	IMP	Homo_sapiens(9606)	Process
GO:0060020	involved_in Bergmann glial cell differentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0060291	involved_in long-term synaptic potentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0060324	involved_in face development	1	IEA	Homo_sapiens(9606)	Process
GO:0060425	involved_in lung morphogenesis	1	IEA	Homo_sapiens(9606)	Process
GO:0060440	involved_in trachea formation	1	IEA	Homo_sapiens(9606)	Process
GO:0060716	involved_in labyrinthine layer blood vessel development	1	IEA	Homo_sapiens(9606)	Process
GO:0061308	involved_in cardiac neural crest cell development involved in heart development	1	IEA	Homo_sapiens(9606)	Process
GO:0070371	involved_in ERK1 and ERK2 cascade	2	IC,IDA	Homo_sapiens(9606)	Process
GO:0070849	involved_in response to epidermal growth factor	1	IDA	Homo_sapiens(9606)	Process
GO:0071276	involved_in cellular response to cadmium ion	1	IMP	Homo_sapiens(9606)	Process
GO:0071356	involved_in cellular response to tumor necrosis factor	1	IEA	Homo_sapiens(9606)	Process
GO:0072584	involved_in caveolin-mediated endocytosis	1	TAS	Homo_sapiens(9606)	Process
GO:0072686	located_in mitotic spindle	1	ISS	Homo_sapiens(9606)	Component
GO:0090170	involved_in regulation of Golgi inheritance	1	TAS	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0120041	acts_upstream_of positive regulation of macrophage proliferation	1	IGI	Homo_sapiens(9606)	Process
GO:1904355	involved_in positive regulation of telomere capping	1	IMP	Homo_sapiens(9606)	Process
GO:1904813	located_in ficolin-1-rich granule lumen	1	TAS	Homo_sapiens(9606)	Component
GO:2000641	involved_in regulation of early endosome to late endosome transport	1	TAS	Homo_sapiens(9606)	Process