RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000100023	Gene ID	23759	Accession	9261
Symbol	PPIL2	Alias	CYC4;CYP60;UBOX7;Cyp-60;hCyP-60	Full Name	peptidylprolyl isomerase like 2
Status	Confidence	Length	34016 bases	Strand	Plus strand
Position	22 : 21666000 - 21700015	RNA binding domain	N.A.
Summary	This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
PPIL2-233	ENST00000680463	1996	No protein	-
PPIL2-230	ENST00000680393	2840	520aa	ENSP00000506542
PPIL2-214	ENST00000679479	2856	No protein	-
PPIL2-215	ENST00000679534	3507	520aa	ENSP00000504893
PPIL2-222	ENST00000679827	2692	510aa	ENSP00000504929
PPIL2-246	ENST00000681956	4168	520aa	ENSP00000506158
PPIL2-240	ENST00000681338	3025	573aa	ENSP00000505107
PPIL2-225	ENST00000680061	3080	520aa	ENSP00000505910
PPIL2-218	ENST00000679580	3238	415aa	ENSP00000506723
PPIL2-239	ENST00000681286	3214	No protein	-
PPIL2-216	ENST00000679540	3005	520aa	ENSP00000506328
PPIL2-221	ENST00000679795	4051	520aa	ENSP00000506144
PPIL2-231	ENST00000680426	3138	No protein	-
PPIL2-210	ENST00000496819	2411	No protein	-
PPIL2-211	ENST00000498109	3277	No protein	-
PPIL2-201	ENST00000335025	4929	520aa	ENSP00000334553
PPIL2-242	ENST00000681394	4115	305aa	ENSP00000506123
PPIL2-202	ENST00000398831	4068	520aa	ENSP00000381812
PPIL2-213	ENST00000679477	3237	549aa	ENSP00000505978
PPIL2-212	ENST00000626352	2625	527aa	ENSP00000486725
PPIL2-206	ENST00000458567	557	160aa	ENSP00000395181
PPIL2-204	ENST00000417788	4213	41aa	ENSP00000406745
PPIL2-219	ENST00000679586	1812	No protein	-
PPIL2-223	ENST00000679857	2503	No protein	-
PPIL2-236	ENST00000680962	3854	305aa	ENSP00000505778
PPIL2-245	ENST00000681791	3070	250aa	ENSP00000505019
PPIL2-220	ENST00000679692	3235	305aa	ENSP00000504937
PPIL2-226	ENST00000680094	3343	614aa	ENSP00000506368
PPIL2-208	ENST00000484439	863	No protein	-
PPIL2-232	ENST00000680434	3381	43aa	ENSP00000505533
PPIL2-227	ENST00000680109	3076	499aa	ENSP00000506219
PPIL2-203	ENST00000406385	3875	520aa	ENSP00000384299
PPIL2-224	ENST00000680022	1523	No protein	-
PPIL2-238	ENST00000681137	3156	101aa	ENSP00000505216
PPIL2-235	ENST00000680860	3062	342aa	ENSP00000506196
PPIL2-229	ENST00000680183	3840	No protein	-
PPIL2-209	ENST00000485930	149	No protein	-
PPIL2-241	ENST00000681353	587	No protein	-
PPIL2-205	ENST00000446951	1926	No protein	-
PPIL2-244	ENST00000681735	3391	No protein	-
PPIL2-217	ENST00000679564	2509	No protein	-
PPIL2-228	ENST00000680113	3672	No protein	-
PPIL2-234	ENST00000680573	2972	No protein	-
PPIL2-243	ENST00000681612	562	No protein	-
PPIL2-207	ENST00000462188	1735	No protein	-
PPIL2-237	ENST00000681027	3437	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
21317	Choice Behavior	4.136e-005	-
21326	Choice Behavior	4.136e-005	-
40234	Platelet Function Tests	5.7000000E-007	-
70553	Electrocardiography	2E-6	24324551
70554	Trypanosoma cruzi	2E-6	24324551

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000209	involved_in protein polyubiquitination	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0000413	involved_in protein peptidyl-prolyl isomerization	1	IEA	Homo_sapiens(9606)	Process
GO:0003755	NOT enables peptidyl-prolyl cis-trans isomerase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005796	located_in Golgi lumen	1	TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0006397	involved_in mRNA processing	1	IEA	Homo_sapiens(9606)	Process
GO:0006457	involved_in protein folding	1	IEA	Homo_sapiens(9606)	Process
GO:0008380	involved_in RNA splicing	1	IEA	Homo_sapiens(9606)	Process
GO:0016018	NOT enables cyclosporin A binding	1	IDA	Homo_sapiens(9606)	Function
GO:0034450	enables ubiquitin-ubiquitin ligase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0061630	enables ubiquitin protein ligase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0071013	part_of catalytic step 2 spliceosome	1	IBA	Homo_sapiens(9606)	Component
GO:0072659	involved_in protein localization to plasma membrane	1	IMP	Homo_sapiens(9606)	Process