Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerDengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000095002 Gene ID 4436 Accession 7325
Symbol MSH2 Alias FCC1;COCA1;HNPCC;LCFS2;MSH-2;hMSH2;HNPCC1;LYNCH1;MMRCS2 Full Name mutS homolog 2
Status Confidence Length 260080 bases Strand Plus strand
Position 2 : 47403067 - 47663146 RNA binding domain MutS_II
Summary This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000496351 MutS_II PF05188 1.5e-22 1
ENSP00000442697 MutS_II PF05188 3.4e-22 1
ENSP00000233146 MutS_II PF05188 4e-22 1
ENSP00000496441 MutS_II PF05188 4.5e-22 1
ENSP00000384199 MutS_II PF05188 4.6e-22 1
ENSP00000495455 MutS_II PF05188 4.6e-22 1
ENSP00000495543 MutS_II PF05188 4.8e-22 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
19497791 Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells. Yunfu Lin 2009-08-06 DNA repair

Transcripts

Name Transcript ID bp Protein Translation ID
MSH2-204 ENST00000543555 3018 868aa ENSP00000442697
MSH2-208 ENST00000645506 7893 924aa ENSP00000495455
MSH2-209 ENST00000646415 4523 938aa ENSP00000495543
MSH2-207 ENST00000645339 3113 918aa ENSP00000496441
MSH2-205 ENST00000644092 5343 558aa ENSP00000496351
MSH2-202 ENST00000406134 3628 921aa ENSP00000384199
MSH2-201 ENST00000233146 3115 934aa ENSP00000233146
MSH2-206 ENST00000644900 3846 883aa ENSP00000495641
MSH2-203 ENST00000467323 313 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
15828Stroke7.2991377E-005-
40612Platelet Function Tests1.5046600E-005-
40613Platelet Function Tests4.3524848E-006-
40617Platelet Function Tests4.4207540E-006-
40620Platelet Function Tests4.0450658E-006-
40627Platelet Function Tests6.0888667E-007-
66965Bronchodilator Agents5E-626634245
66966Lung Volume Measurements5E-626634245
79898Alzheimer Disease8E-726830138
79899Age of Onset8E-726830138
101957Alpha Rhythm7E-625387704
101958Brain Waves7E-625387704

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000095002homo_sapiensENSP0000023442028.676516.8382homo_sapiensENSP0000023314641.755924.5182
ENSG00000095002homo_sapiensENSP0000026318736.324820.9402homo_sapiensENSP0000023314636.402620.985
ENSG00000095002homo_sapiensENSP0000036490336.091120.2638homo_sapiensENSP0000023314632.22718.0942
ENSG00000095002homo_sapiensENSP0000026508134.212820.1407homo_sapiensENSP0000023314641.648824.5182

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000095002homo_sapiensENSP0000023314699.892999.7859nomascus_leucogenysENSNLEP0000002363799.892999.7859
ENSG00000095002homo_sapiensENSP0000023314699.892999.8929pan_paniscusENSPPAP0000002200499.892999.8929
ENSG00000095002homo_sapiensENSP00000233146100100pongo_abeliiENSPPYP00000044661100100
ENSG00000095002homo_sapiensENSP0000023314691.327691.1135pan_troglodytesENSPTRP0000006638398.612798.3815
ENSG00000095002homo_sapiensENSP0000023314610099.8929gorilla_gorillaENSGGOP0000000694010099.8929
ENSG00000095002homo_sapiensENSP0000023314691.9781.0492ornithorhynchus_anatinusENSOANP0000002120090.995880.1907
ENSG00000095002homo_sapiensENSP0000023314693.57685.9743sarcophilus_harrisiiENSSHAP0000000052493.57685.9743
ENSG00000095002homo_sapiensENSP0000023314670.235565.2034notamacropus_eugeniiENSMEUP0000001290383.673577.6786
ENSG00000095002homo_sapiensENSP0000023314663.383361.349choloepus_hoffmanniENSCHOP0000000312388.358285.5224
ENSG00000095002homo_sapiensENSP0000023314695.610391.7559dasypus_novemcinctusENSDNOP0000000914095.202691.3646
ENSG00000095002homo_sapiensENSP0000023314677.301974.6253erinaceus_europaeusENSEEUP0000001430077.467874.7854
ENSG00000095002homo_sapiensENSP0000023314664.132861.349echinops_telfairiENSETEP0000001518564.270461.4807
ENSG00000095002homo_sapiensENSP0000023314699.357698.2869callithrix_jacchusENSCJAP0000000107699.357698.2869
ENSG00000095002homo_sapiensENSP0000023314699.250599.1435cercocebus_atysENSCATP0000003640099.356999.2497
ENSG00000095002homo_sapiensENSP0000023314699.464799.3576macaca_fascicularisENSMFAP0000000399499.571399.4641
ENSG00000095002homo_sapiensENSP0000023314699.464799.3576macaca_mulattaENSMMUP0000003655999.571399.4641
ENSG00000095002homo_sapiensENSP0000023314699.464799.3576macaca_nemestrinaENSMNEP0000002609299.571399.4641
ENSG00000095002homo_sapiensENSP0000023314699.464799.3576papio_anubisENSPANP0000000509099.571399.4641
ENSG00000095002homo_sapiensENSP0000023314689.935889.8287mandrillus_leucophaeusENSMLEP0000000640499.408399.2899
ENSG00000095002homo_sapiensENSP0000023314697.751695.0749tursiops_truncatusENSTTRP0000000400198.066695.3813
ENSG00000095002homo_sapiensENSP0000023314689.935888.0086vulpes_vulpesENSVVUP0000000744198.591696.4789
ENSG00000095002homo_sapiensENSP0000023314696.466892.6124mus_spretusMGP_SPRETEiJ_P004774296.363692.5134
ENSG00000095002homo_sapiensENSP0000023314698.608196.6809equus_asinusENSEASP0000500389998.608196.6809
ENSG00000095002homo_sapiensENSP0000023314697.644594.9679capra_hircusENSCHIP0000002500996.405993.7632
ENSG00000095002homo_sapiensENSP0000023314689.828785.546loxodonta_africanaENSLAFP0000001454796.326191.7336
ENSG00000095002homo_sapiensENSP0000023314698.072895.8244panthera_leoENSPLOP0000000546998.072895.8244
ENSG00000095002homo_sapiensENSP0000023314698.286996.2527ailuropoda_melanoleucaENSAMEP0000000662998.286996.2527
ENSG00000095002homo_sapiensENSP0000023314697.858795.2891bos_indicus_hybridENSBIXP0000501781097.858795.2891
ENSG00000095002homo_sapiensENSP0000023314691.006488.8651oryctolagus_cuniculusENSOCUP0000000825498.265995.9538
ENSG00000095002homo_sapiensENSP0000023314690.149987.045equus_caballusENSECAP0000007220987.891484.8643
ENSG00000095002homo_sapiensENSP0000023314698.39496.1456canis_lupus_familiarisENSCAFP0084500746598.39496.1456
ENSG00000095002homo_sapiensENSP0000023314697.965795.7173panthera_pardusENSPPRP0000000329497.965795.7173
ENSG00000095002homo_sapiensENSP0000023314689.186386.6167marmota_marmota_marmotaENSMMMP0000001105995.637292.8817
ENSG00000095002homo_sapiensENSP0000023314694.967992.6124balaenoptera_musculusENSBMSP0001001620597.902995.4746
ENSG00000095002homo_sapiensENSP0000023314697.965794.7537cavia_porcellusENSCPOP0000001288097.965794.7537
ENSG00000095002homo_sapiensENSP0000023314698.072895.9315felis_catusENSFCAP0000001247498.072895.9315
ENSG00000095002homo_sapiensENSP0000023314698.501196.2527ursus_americanusENSUAMP0000001771998.501196.2527
ENSG00000095002homo_sapiensENSP0000023314660.920854.4968monodelphis_domesticaENSMODP0000003093488.767579.4072
ENSG00000095002homo_sapiensENSP0000023314693.361985.9743monodelphis_domesticaENSMODP0000000130889.989782.8689
ENSG00000095002homo_sapiensENSP0000023314697.751695.182bison_bison_bisonENSBBBP0000001680297.751695.182
ENSG00000095002homo_sapiensENSP0000023314698.286995.6103monodon_monocerosENSMMNP0001501578498.286995.6103
ENSG00000095002homo_sapiensENSP0000023314697.109294.1114sus_scrofaENSSSCP0000000899798.58795.5435
ENSG00000095002homo_sapiensENSP0000023314698.501196.5739microcebus_murinusENSMICP0000002501098.501196.5739
ENSG00000095002homo_sapiensENSP0000023314681.263477.0878octodon_degusENSODEP0000001743788.358683.8184
ENSG00000095002homo_sapiensENSP0000023314682.762378.1585jaculus_jaculusENSJJAP0000000831692.133587.0083
ENSG00000095002homo_sapiensENSP0000023314696.359793.7902ovis_aries_rambouilletENSOARP0002000626095.948893.3902
ENSG00000095002homo_sapiensENSP0000023314695.931593.7902ursus_maritimusENSUMAP0000001792798.569996.3696
ENSG00000095002homo_sapiensENSP0000023314679.871576.4454ochotona_princepsENSOPRP0000000258781.88878.3754
ENSG00000095002homo_sapiensENSP0000023314698.286995.7173delphinapterus_leucasENSDLEP0000000119498.286995.7173
ENSG00000095002homo_sapiensENSP0000023314697.965795.6103physeter_catodonENSPCTP0000501736797.965795.6103
ENSG00000095002homo_sapiensENSP0000023314696.466891.97mus_caroliMGP_CAROLIEiJ_P004581896.260791.7735
ENSG00000095002homo_sapiensENSP0000023314696.466892.5054mus_musculusENSMUSP0000002496796.363692.4064
ENSG00000095002homo_sapiensENSP0000023314681.370576.1242dipodomys_ordiiENSDORP0000002474291.787485.8696
ENSG00000095002homo_sapiensENSP0000023314698.179994.8608mustela_putorius_furoENSMPUP0000001093998.179994.8608
ENSG00000095002homo_sapiensENSP0000023314692.077191.3276aotus_nancymaaeENSANAP0000001407899.307298.4988
ENSG00000095002homo_sapiensENSP0000023314684.796682.5482saimiri_boliviensis_boliviensisENSSBOP0000002186995.192392.6683
ENSG00000095002homo_sapiensENSP0000023314690.25787.045vicugna_pacosENSVPAP0000000321497.682594.2063
ENSG00000095002homo_sapiensENSP0000023314699.357699.1435chlorocebus_sabaeusENSCSAP0000000973199.464199.2497
ENSG00000095002homo_sapiensENSP0000023314675.695973.6617tupaia_belangeriENSTBEP0000000395377.183475.1092
ENSG00000095002homo_sapiensENSP0000023314696.680992.7195mesocricetus_auratusENSMAUP0000002178696.680992.7195
ENSG00000095002homo_sapiensENSP0000023314698.179995.5032phocoena_sinusENSPSNP0000001257298.179995.5032
ENSG00000095002homo_sapiensENSP0000023314695.931591.97camelus_dromedariusENSCDRP0000503285695.624391.6756
ENSG00000095002homo_sapiensENSP0000023314697.430495.3961carlito_syrichtaENSTSYP0000000917198.378496.3243
ENSG00000095002homo_sapiensENSP0000023314675.588969.2719carlito_syrichtaENSTSYP0000002298687.920380.5729
ENSG00000095002homo_sapiensENSP0000023314698.072895.8244panthera_tigris_altaicaENSPTIP0000000310098.072895.8244
ENSG00000095002homo_sapiensENSP0000023314697.109292.6124rattus_norvegicusENSRNOP0000002153897.213392.7117
ENSG00000095002homo_sapiensENSP0000023314689.293486.5096prolemur_simusENSPSMP0000001578092.154789.2818
ENSG00000095002homo_sapiensENSP0000023314693.468988.651microtus_ochrogasterENSMOCP0000000441395.618890.69
ENSG00000095002homo_sapiensENSP0000023314683.404779.015sorex_araneusENSSARP0000000734083.494179.0997
ENSG00000095002homo_sapiensENSP0000023314697.002192.6124peromyscus_maniculatus_bairdiiENSPEMP0000001630497.106192.7117
ENSG00000095002homo_sapiensENSP0000023314697.751695.182bos_mutusENSBMUP0000000668597.751695.182
ENSG00000095002homo_sapiensENSP0000023314689.186385.439mus_spicilegusENSMSIP0000001150196.078492.0415
ENSG00000095002homo_sapiensENSP0000023314697.002193.2548cricetulus_griseus_chok1gshdENSCGRP0000102703597.002193.2548
ENSG00000095002homo_sapiensENSP0000023314697.430494.9679pteropus_vampyrusENSPVAP0000000491497.430494.9679
ENSG00000095002homo_sapiensENSP0000023314695.503292.3983myotis_lucifugusENSMLUP0000001004294.994791.9063
ENSG00000095002homo_sapiensENSP0000023314693.040785.1178vombatus_ursinusENSVURP0001001998893.040785.1178
ENSG00000095002homo_sapiensENSP0000023314697.430494.6467rhinolophus_ferrumequinumENSRFEP0001000783897.430494.6467
ENSG00000095002homo_sapiensENSP0000023314694.860891.4347neovison_visonENSNVIP0000003011695.474192.0259
ENSG00000095002homo_sapiensENSP0000023314697.858795.2891bos_taurusENSBTAP0000000355697.858795.2891
ENSG00000095002homo_sapiensENSP0000023314697.002194.4325heterocephalus_glaber_femaleENSHGLP0000001837297.002194.4325
ENSG00000095002homo_sapiensENSP0000023314699.464799.1435rhinopithecus_bietiENSRBIP0000001464199.678199.3562
ENSG00000095002homo_sapiensENSP0000023314689.935887.9015canis_lupus_dingoENSCAFP0002003401698.591696.3615
ENSG00000095002homo_sapiensENSP0000023314645.824444.3255sciurus_vulgarisENSSVLP0000502504294.273191.1894
ENSG00000095002homo_sapiensENSP0000023314698.608196.4668sciurus_vulgarisENSSVLP0000502877398.608196.4668
ENSG00000095002homo_sapiensENSP0000023314647.537545.8244sciurus_vulgarisENSSVLP0000500558593.868990.4863
ENSG00000095002homo_sapiensENSP0000023314632.548231.3704sciurus_vulgarisENSSVLP0000500604093.538590.1538
ENSG00000095002homo_sapiensENSP0000023314645.610343.6831sciurus_vulgarisENSSVLP0000500592390.638386.8085
ENSG00000095002homo_sapiensENSP0000023314692.933684.9036phascolarctos_cinereusENSPCIP0000003512892.933684.9036
ENSG00000095002homo_sapiensENSP0000023314662.419759.4218procavia_capensisENSPCAP0000000255766.476663.2839
ENSG00000095002homo_sapiensENSP0000023314697.751694.0043nannospalax_galiliENSNGAP0000002170897.751694.0043
ENSG00000095002homo_sapiensENSP0000023314695.717393.1478bos_grunniensENSBGRP0000001472297.811895.186
ENSG00000095002homo_sapiensENSP0000023314684.582481.9058chinchilla_lanigeraENSCLAP0000000431597.290694.2118
ENSG00000095002homo_sapiensENSP0000023314698.072895.5032cervus_hanglu_yarkandensisENSCHYP0000002801298.072895.5032
ENSG00000095002homo_sapiensENSP0000023314698.501196.1456catagonus_wagneriENSCWAP0000000501398.501196.1456
ENSG00000095002homo_sapiensENSP0000023314698.179996.1456ictidomys_tridecemlineatusENSSTOP0000000637298.179996.1456
ENSG00000095002homo_sapiensENSP0000023314689.935887.152otolemur_garnettiiENSOGAP0000001388596.440993.4558
ENSG00000095002homo_sapiensENSP0000023314699.250598.394cebus_imitatorENSCCAP0000000387699.250598.394
ENSG00000095002homo_sapiensENSP0000023314698.179996.2527urocitellus_parryiiENSUPAP0001002601598.179996.2527
ENSG00000095002homo_sapiensENSP0000023314692.612489.6146moschus_moschiferusENSMMSP0000000756696.004492.8968
ENSG00000095002homo_sapiensENSP0000023314697.751695.182moschus_moschiferusENSMMSP0000001304497.751695.182
ENSG00000095002homo_sapiensENSP0000023314699.678899.3576rhinopithecus_roxellanaENSRROP0000000062699.678899.3576
ENSG00000095002homo_sapiensENSP0000023314696.680992.9336mus_pahariMGP_PahariEiJ_P004533096.784693.0332
ENSG00000095002homo_sapiensENSP0000023314687.366283.94propithecus_coquereliENSPCOP0000000581594.009290.3226
ENSG00000095002homo_sapiensENSP0000023314649.036428.9079caenorhabditis_elegansH26D21.2.153.945831.8021
ENSG00000095002homo_sapiensENSP0000023314662.419741.1135drosophila_melanogasterFBpp030120863.576941.8757
ENSG00000095002homo_sapiensENSP0000023314669.164951.1777ciona_intestinalisENSCINP0000001297168.504850.6893
ENSG00000095002homo_sapiensENSP0000023314631.477526.7666petromyzon_marinusENSPMAP0000000535381.894169.6379
ENSG00000095002homo_sapiensENSP0000023314679.336263.5974eptatretus_burgeriENSEBUP0000000606177.836162.395
ENSG00000095002homo_sapiensENSP0000023314684.582471.8415callorhinchus_miliiENSCMIP0000000799184.49271.7647
ENSG00000095002homo_sapiensENSP0000023314642.933637.152latimeria_chalumnaeENSLACP0000000062889.709277.6286
ENSG00000095002homo_sapiensENSP0000023314687.366273.1263lepisosteus_oculatusENSLOCP0000002012387.086472.8922
ENSG00000095002homo_sapiensENSP0000023314687.473272.0557danio_rerioENSDARP0000002776887.286371.9017
ENSG00000095002homo_sapiensENSP0000023314687.366272.6981carassius_auratusENSCARP0000001169987.647772.9323
ENSG00000095002homo_sapiensENSP0000023314685.54671.0921carassius_auratusENSCARP000000822958570.6383
ENSG00000095002homo_sapiensENSP0000023314687.473273.6617astyanax_mexicanusENSAMXP0000001633987.007573.2694
ENSG00000095002homo_sapiensENSP0000023314687.04572.591ictalurus_punctatusENSIPUP0000001247986.673872.2814
ENSG00000095002homo_sapiensENSP0000023314681.049263.1692esox_luciusENSELUP0000006906078.690261.3306
ENSG00000095002homo_sapiensENSP0000023314686.616771.8415electrophorus_electricusENSEEEP0000003566086.155571.459
ENSG00000095002homo_sapiensENSP0000023314681.156364.3469oncorhynchus_kisutchENSOKIP0000506904079.288762.8661
ENSG00000095002homo_sapiensENSP0000023314680.406963.5974oncorhynchus_mykissENSOMYP0000001130880.579463.7339
ENSG00000095002homo_sapiensENSP0000023314680.728164.7752salmo_salarENSSSAP0000009976277.73262.3711
ENSG00000095002homo_sapiensENSP0000023314680.728164.7752salmo_truttaENSSTUP0000008227881.162565.1238
ENSG00000095002homo_sapiensENSP0000023314679.764563.8116gadus_morhuaENSGMOP0000003291878.669562.9356
ENSG00000095002homo_sapiensENSP0000023314645.18235.9743fundulus_heteroclitusENSFHEP0000002468980.534364.1221
ENSG00000095002homo_sapiensENSP0000023314640.578231.6916fundulus_heteroclitusENSFHEP0000003357480.810263.113
ENSG00000095002homo_sapiensENSP0000023314682.655265.7388poecilia_reticulataENSPREP0000000757182.390665.5283
ENSG00000095002homo_sapiensENSP0000023314616.0612.5268xiphophorus_maculatusENSXMAP0000003438765.789551.3158
ENSG00000095002homo_sapiensENSP0000023314626.445421.6274xiphophorus_maculatusENSXMAP0000002531170.370457.5499
ENSG00000095002homo_sapiensENSP0000023314682.762365.9529xiphophorus_maculatusENSXMAP0000001442382.497365.7417
ENSG00000095002homo_sapiensENSP0000023314682.655266.167oryzias_latipesENSORLP0000001287382.655266.167
ENSG00000095002homo_sapiensENSP0000023314681.798765.9529cyclopterus_lumpusENSCLMP0000503884281.798765.9529
ENSG00000095002homo_sapiensENSP0000023314682.655265.5246oreochromis_niloticusENSONIP0000007771481.953364.9682
ENSG00000095002homo_sapiensENSP0000023314682.548265.2034haplochromis_burtoniENSHBUP0000003542477.02360.8392
ENSG00000095002homo_sapiensENSP0000023314680.085763.4904astatotilapia_callipteraENSACLP0000000310881.570364.6674
ENSG00000095002homo_sapiensENSP0000023314683.190666.9165sparus_aurataENSSAUP0001006738882.835866.6311
ENSG00000095002homo_sapiensENSP0000023314679.550364.3469lates_calcariferENSLCAP0001003846581.828266.1894
ENSG00000095002homo_sapiensENSP0000023314690.042878.0514xenopus_tropicalisENSXETP0000010031588.247676.4953
ENSG00000095002homo_sapiensENSP0000023314688.115678.5867chrysemys_picta_belliiENSCPBP0000001564287.646478.1683
ENSG00000095002homo_sapiensENSP0000023314681.905871.5203sphenodon_punctatusENSSPUP0000001772089.894278.4959
ENSG00000095002homo_sapiensENSP0000023314688.329878.0514crocodylus_porosusENSCPRP0000502099687.859477.6358
ENSG00000095002homo_sapiensENSP0000023314653.104942.7195laticauda_laticaudataENSLLTP0000001820178.605463.233
ENSG00000095002homo_sapiensENSP0000023314629.443325.3747laticauda_laticaudataENSLLTP0000002176577.683666.9492
ENSG00000095002homo_sapiensENSP0000023314680.62168.9508notechis_scutatusENSNSUP0000002252681.847870
ENSG00000095002homo_sapiensENSP0000023314679.01567.9872pseudonaja_textilisENSPTXP0000001157086.823574.7059
ENSG00000095002homo_sapiensENSP0000023314689.614678.3726anas_platyrhynchos_platyrhynchosENSAPLP0000001528689.137477.9553
ENSG00000095002homo_sapiensENSP0000023314687.901577.7302gallus_gallusENSGALP0001002531888.469878.2328
ENSG00000095002homo_sapiensENSP0000023314685.43975.2677meleagris_gallopavoENSMGAP0000000506590.271579.5249
ENSG00000095002homo_sapiensENSP0000023314683.404773.6617serinus_canariaENSSCAP0000001638891.539480.8461
ENSG00000095002homo_sapiensENSP0000023314689.079278.2655parus_majorENSPMJP0000000505988.888978.0983
ENSG00000095002homo_sapiensENSP0000023314685.224871.4133anolis_carolinensisENSACAP0000001379483.525769.9895
ENSG00000095002homo_sapiensENSP0000023314675.80360.2784neolamprologus_brichardiENSNBRP0000001449980.821964.2694
ENSG00000095002homo_sapiensENSP0000023314685.224872.8051naja_najaENSNNAP0000000048984.77172.4175
ENSG00000095002homo_sapiensENSP0000023314684.475468.5225podarcis_muralisENSPMRP0000000188982.878267.2269
ENSG00000095002homo_sapiensENSP0000023314683.404773.8758geospiza_fortisENSGFOP0000000681091.539481.0811
ENSG00000095002homo_sapiensENSP0000023314689.507578.6938taeniopygia_guttataENSTGUP0000000570989.316278.5256
ENSG00000095002homo_sapiensENSP0000023314689.400476.9807erpetoichthys_calabaricusENSECRP0000002893189.496277.0632
ENSG00000095002homo_sapiensENSP0000023314682.548265.6317kryptolebias_marmoratusENSKMAP0000001569982.548265.6317
ENSG00000095002homo_sapiensENSP0000023314685.43970.985salvator_merianaeENSSMRP000000191298469.7895
ENSG00000095002homo_sapiensENSP0000023314682.976467.1306oryzias_javanicusENSOJAP0000003955482.976467.1306
ENSG00000095002homo_sapiensENSP0000023314681.049264.3469amphilophus_citrinellusENSACIP0000000414681.749564.9028
ENSG00000095002homo_sapiensENSP0000023314682.655267.3448dicentrarchus_labraxENSDLAP0000505444382.478667.2009
ENSG00000095002homo_sapiensENSP0000023314683.083566.2741amphiprion_perculaENSAPEP0000003172082.994766.2032
ENSG00000095002homo_sapiensENSP0000023314682.976466.167oryzias_sinensisENSOSIP0000004859378.920662.9328
ENSG00000095002homo_sapiensENSP0000023314683.190673.8758pelodiscus_sinensisENSPSIP0000001800789.722979.6767
ENSG00000095002homo_sapiensENSP0000023314688.008678.4797gopherus_evgoodeiENSGEVP0000500040287.539978.0618
ENSG00000095002homo_sapiensENSP0000023314628.693826.2313chelonoidis_abingdoniiENSCABP0000003055592.096284.1924
ENSG00000095002homo_sapiensENSP0000023314629.978626.1242chelonoidis_abingdoniiENSCABP0000003055283.582172.8358
ENSG00000095002homo_sapiensENSP0000023314681.477565.8458seriola_dumeriliENSSDUP0000002195081.652465.9871
ENSG00000095002homo_sapiensENSP0000023314681.798766.2741cottoperca_gobioENSCGOP0000001772381.711266.2032
ENSG00000095002homo_sapiensENSP0000023314684.689574.9465struthio_camelus_australisENSSCUP0000000561890.919580.4598
ENSG00000095002homo_sapiensENSP0000023314689.186378.3726anser_brachyrhynchusENSABRP0000002155076.632967.3413
ENSG00000095002homo_sapiensENSP0000023314680.62165.2034gasterosteus_aculeatusENSGACP0000000361982.747366.9231
ENSG00000095002homo_sapiensENSP0000023314681.691765.3105cynoglossus_semilaevisENSCSEP0000001508181.691765.3105
ENSG00000095002homo_sapiensENSP0000023314682.655265.7388poecilia_formosaENSPFOP0000000985982.390665.5283
ENSG00000095002homo_sapiensENSP0000023314682.869466.06myripristis_murdjanENSMMDP0000505583582.780765.9893
ENSG00000095002homo_sapiensENSP0000023314681.691765.7388sander_luciopercaENSSLUP0000002482779.067463.6269
ENSG00000095002homo_sapiensENSP0000023314689.293478.6938strigops_habroptilaENSSHBP0000501786988.25477.7778
ENSG00000095002homo_sapiensENSP0000023314682.869466.3812amphiprion_ocellarisENSAOCP0000001643182.780766.3102
ENSG00000095002homo_sapiensENSP0000023314624.19721.5203terrapene_carolina_triunguisENSTMTP0000002605189.328179.4466
ENSG00000095002homo_sapiensENSP0000023314630.192726.5525terrapene_carolina_triunguisENSTMTP0000000791281.26871.4697
ENSG00000095002homo_sapiensENSP0000023314680.835164.454hucho_huchoENSHHUP0000002094481.182864.7312
ENSG00000095002homo_sapiensENSP0000023314681.584666.167betta_splendensENSBSLP0000005718181.410366.0256
ENSG00000095002homo_sapiensENSP0000023314687.473273.0193pygocentrus_nattereriENSPNAP0000002468886.914972.5532
ENSG00000095002homo_sapiensENSP0000023314682.441166.9165anabas_testudineusENSATEP0000006172882.352966.8449
ENSG00000095002homo_sapiensENSP0000023314668.308350.1071ciona_savignyiENSCSAVP0000000799567.157949.2632
ENSG00000095002homo_sapiensENSP0000023314663.169241.5418saccharomyces_cerevisiaeYOL090W61.203340.249
ENSG00000095002homo_sapiensENSP0000023314682.119966.2741seriola_lalandi_dorsalisENSSLDP0000002209182.032166.2032
ENSG00000095002homo_sapiensENSP0000023314622.376917.2377labrus_bergyltaENSLBEP0000000033377.407459.6296
ENSG00000095002homo_sapiensENSP0000023314682.22765.4176labrus_bergyltaENSLBEP0000003599382.13965.3476
ENSG00000095002homo_sapiensENSP0000023314652.248441.97labrus_bergyltaENSLBEP0000000027281.333365.3333
ENSG00000095002homo_sapiensENSP0000023314682.655265.4176pundamilia_nyerereiENSPNYP0000000455982.566865.3476
ENSG00000095002homo_sapiensENSP0000023314682.33466.06mastacembelus_armatusENSMAMP0000000164582.24665.9893
ENSG00000095002homo_sapiensENSP0000023314674.732359.743stegastes_partitusENSSPAP0000002476081.637465.2632
ENSG00000095002homo_sapiensENSP0000023314681.049264.3469oncorhynchus_tshawytschaENSOTSP0000505283781.397964.6237
ENSG00000095002homo_sapiensENSP0000023314640.25731.7987acanthochromis_polyacanthusENSAPOP0000000078582.819465.4185
ENSG00000095002homo_sapiensENSP0000023314614.775212.6338acanthochromis_polyacanthusENSAPOP0000001583478.857167.4286
ENSG00000095002homo_sapiensENSP0000023314690.042879.2291aquila_chrysaetos_chrysaetosENSACCP0002002325989.850479.0598
ENSG00000095002homo_sapiensENSP0000023314674.304159.9572nothobranchius_furzeriENSNFUP0001503600277.111162.2222
ENSG00000095002homo_sapiensENSP0000023314682.655266.167cyprinodon_variegatusENSCVAP0000000448382.390665.9552
ENSG00000095002homo_sapiensENSP0000023314685.224869.9143denticeps_clupeoidesENSDCDP0000003792684.861469.6162
ENSG00000095002homo_sapiensENSP0000023314682.762366.7024larimichthys_croceaENSLCRP0000504982782.585566.5598
ENSG00000095002homo_sapiensENSP0000023314683.297673.7687ficedula_albicollisENSFALP0000001163491.421980.9636
ENSG00000095002homo_sapiensENSP0000023314679.978662.848hippocampus_comesENSHCOP0000001310078.964162.0507
ENSG00000095002homo_sapiensENSP0000023314686.723872.3769cyprinus_carpio_carpioENSCCRP0000013565786.538572.2222
ENSG00000095002homo_sapiensENSP0000023314687.15272.591cyprinus_carpio_carpioENSCCRP0000016861886.965872.4359
ENSG00000095002homo_sapiensENSP0000023314688.865177.6231coturnix_japonicaENSCJPP0000500147888.110476.9639
ENSG00000095002homo_sapiensENSP0000023314682.655265.6317poecilia_latipinnaENSPLAP0000001940982.390665.4216
ENSG00000095002homo_sapiensENSP0000023314686.723872.0557sinocyclocheilus_grahamiENSSGRP0000004194386.538571.9017
ENSG00000095002homo_sapiensENSP0000023314684.475469.9143sinocyclocheilus_grahamiENSSGRP0000008750983.403869.0275
ENSG00000095002homo_sapiensENSP0000023314682.548265.4176maylandia_zebraENSMZEP0000500316382.283965.2081
ENSG00000095002homo_sapiensENSP0000023314616.809414.1328tetraodon_nigroviridisENSTNIP0000000450074.056662.2642
ENSG00000095002homo_sapiensENSP0000023314680.728163.1692tetraodon_nigroviridisENSTNIP0000000619679.957662.5663
ENSG00000095002homo_sapiensENSP0000023314671.092158.03paramormyrops_kingsleyaeENSPKIP0000002638484.478468.9567
ENSG00000095002homo_sapiensENSP0000023314687.366271.7345scleropages_formosusENSSFOP0001507706086.90171.3525
ENSG00000095002homo_sapiensENSP0000023314690.36479.8715leptobrachium_leishanenseENSLLEP0000001851590.655280.1289
ENSG00000095002homo_sapiensENSP0000023314681.370564.561scophthalmus_maximusENSSMAP0000007018278.108961.9733
ENSG00000095002homo_sapiensENSP0000023314682.655266.7024oryzias_melastigmaENSOMEP0000000821682.655266.7024

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000287contributes_to magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0000400contributes_to four-way junction DNA binding1IDAHomo_sapiens(9606)Function
GO:0000781located_in chromosome, telomeric region1HDAHomo_sapiens(9606)Component
GO:0001701involved_in in utero embryonic development1IEAHomo_sapiens(9606)Process
GO:0002204involved_in somatic recombination of immunoglobulin genes involved in immune response1IBAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1IDAHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1IDAHomo_sapiens(9606)Function
GO:0003690contributes_to double-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0003697contributes_to single-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524contributes_to ATP binding1IDAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0006119involved_in oxidative phosphorylation1IEAHomo_sapiens(9606)Process
GO:0006281involved_in DNA repair1IDAHomo_sapiens(9606)Process
GO:0006298involved_in mismatch repair4IBA,IDA,IGIHomo_sapiens(9606)Process
GO:0006301involved_in postreplication repair1IDAHomo_sapiens(9606)Process
GO:0006302involved_in double-strand break repair1IEAHomo_sapiens(9606)Process
GO:0006312involved_in mitotic recombination1IBAHomo_sapiens(9606)Process
GO:0007281involved_in germ cell development1IEAHomo_sapiens(9606)Process
GO:0008094enables ATP-dependent activity, acting on DNA1IDAHomo_sapiens(9606)Function
GO:0008340involved_in determination of adult lifespan1IEAHomo_sapiens(9606)Process
GO:0008584involved_in male gonad development1ISSHomo_sapiens(9606)Process
GO:0010165involved_in response to X-ray1ISSHomo_sapiens(9606)Process
GO:0010224involved_in response to UV-B1ISSHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016446involved_in somatic hypermutation of immunoglobulin genes1IEAHomo_sapiens(9606)Process
GO:0016447involved_in somatic recombination of immunoglobulin gene segments1ISSHomo_sapiens(9606)Process
GO:0016887enables ATP hydrolysis activity1IEAHomo_sapiens(9606)Function
GO:0019237enables centromeric DNA binding1IEAHomo_sapiens(9606)Function
GO:0019724involved_in B cell mediated immunity1ISSHomo_sapiens(9606)Process
GO:0030183involved_in B cell differentiation1ISSHomo_sapiens(9606)Process
GO:0030983contributes_to mismatched DNA binding1IDAHomo_sapiens(9606)Function
GO:0031573involved_in mitotic intra-S DNA damage checkpoint signaling1IEAHomo_sapiens(9606)Process
GO:0032137contributes_to guanine/thymine mispair binding2IDA,IMPHomo_sapiens(9606)Function
GO:0032139contributes_to dinucleotide insertion or deletion binding1IDAHomo_sapiens(9606)Function
GO:0032142contributes_to single guanine insertion binding1IDAHomo_sapiens(9606)Function
GO:0032143contributes_to single thymine insertion binding1IDAHomo_sapiens(9606)Function
GO:0032181contributes_to dinucleotide repeat insertion binding1IDAHomo_sapiens(9606)Function
GO:0032301part_of MutSalpha complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0032302part_of MutSbeta complex2IDA,IPIHomo_sapiens(9606)Component
GO:0032357contributes_to oxidized purine DNA binding1IDAHomo_sapiens(9606)Function
GO:0032405contributes_to MutLalpha complex binding1IDAHomo_sapiens(9606)Function
GO:0042771involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator1IEAHomo_sapiens(9606)Process
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0043524involved_in negative regulation of neuron apoptotic process1ISSHomo_sapiens(9606)Process
GO:0043531contributes_to ADP binding1IDAHomo_sapiens(9606)Function
GO:0043570involved_in maintenance of DNA repeat elements1IMPHomo_sapiens(9606)Process
GO:0045190involved_in isotype switching1ISSHomo_sapiens(9606)Process
GO:0045910involved_in negative regulation of DNA recombination2IDA,ISSHomo_sapiens(9606)Process
GO:0048298involved_in positive regulation of isotype switching to IgA isotypes1IEAHomo_sapiens(9606)Process
GO:0048304involved_in positive regulation of isotype switching to IgG isotypes1IEAHomo_sapiens(9606)Process
GO:0051096involved_in positive regulation of helicase activity1IDAHomo_sapiens(9606)Process
GO:0071168involved_in protein localization to chromatin1IMPHomo_sapiens(9606)Process
GO:0140664enables ATP-dependent DNA damage sensor activity1IEAHomo_sapiens(9606)Function

Expression