RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerDengue
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	DataSet_02_73

Description

Ensembl ID	ENSG00000091127	Gene ID	54517	Accession	26033
Symbol	PUS7	Alias	IDDABS	Full Name	pseudouridine synthase 7
Status	Confidence	Length	82611 bases	Strand	Minus strand
Position	7 : 105439661 - 105522271	RNA binding domain	TruD
Summary	Enables enzyme binding activity and pseudouridine synthase activity. Involved in several processes, including pseudouridine synthesis; regulation of hematopoietic stem cell differentiation; and regulation of mesoderm development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000348722	TruD	PF01142	6.3e-73	1
ENSP00000417402	TruD	PF01142	6.3e-73	1
ENSP00000418794	TruD	PF01142	1.3e-45	1

Showing 1 to 3 of 3 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hela_human	Hela	Alfredo Castello	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22681889	RIC_PMID22681889_Hs_HEK293	HEK293	Alexander G Baltz	2012 Jun 8	doi: 10.1016/j.molcel.2012.05.021
26632259	RIC_PMID26632259._Hs_HuH7	HuH7	Benedikt M Beckmann	2015 Dec 3	doi: 10.1038/ncomms10127.
29431736	RICK_PMID29431736_Hs_HeLa.RICK	HeLa	Xichen Bao	2018 Mar	doi: 10.1038/nmeth.4595.?Epub 2018 Feb 12
29636419	CARIC_PMID29636419_Hs_CARIC		Rongbing Huang	2018 Apr 24	doi: 10.1073/pnas.1718406115
30352994	eRIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30352994	eRIC_PMID30352994_Jurkat_human	Jurkat	Joel I Perez-Perri?	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30352994	RIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6

Showing 1 to 10 of 19 entries

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
PUS7-201	ENST00000356362	3480	661aa	ENSP00000348722
PUS7-202	ENST00000469408	3525	661aa	ENSP00000417402
PUS7-203	ENST00000478208	620	No protein	-
PUS7-204	ENST00000481939	2436	448aa	ENSP00000418794
PUS7-205	ENST00000482157	395	132aa	ENSP00000417718
PUS7-206	ENST00000487277	275	No protein	-

Showing 1 to 6 of 6 entries

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Gene Model

Click here to download ENSG00000091127's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
32516	Blood Pressure	5.1512904E-005	-
38662	Platelet Function Tests	2.0200000E-006	-
38667	Platelet Function Tests	1.2600000E-006	-
38668	Platelet Function Tests	1.2600000E-006	-
38669	Platelet Function Tests	1.2600000E-006	-
38675	Platelet Function Tests	1.2600000E-006	-
40233	Platelet Function Tests	4.5400000E-007	-
40244	Platelet Function Tests	2.0300000E-007	-
40245	Platelet Function Tests	2.0300000E-007	-
40246	Platelet Function Tests	2.0300000E-007	-

Showing 1 to 10 of 13 entries

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000091127's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000091127	homo_sapiens	ENSP00000343081	41.5121	24.5364	homo_sapiens	ENSP00000417402	44.0242	26.0212

Showing 1 to 1 of 1 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000091127	homo_sapiens	ENSP00000417402	99.3949	99.2436	nomascus_leucogenys	ENSNLEP00000010956	99.3949	99.2436
ENSG00000091127	homo_sapiens	ENSP00000417402	100	100	pan_paniscus	ENSPPAP00000041865	100	100
ENSG00000091127	homo_sapiens	ENSP00000417402	99.6974	99.0923	pongo_abelii	ENSPPYP00000020055	99.6974	99.0923
ENSG00000091127	homo_sapiens	ENSP00000417402	100	100	pan_troglodytes	ENSPTRP00000033508	100	100
ENSG00000091127	homo_sapiens	ENSP00000417402	100	99.8487	pan_troglodytes	ENSPTRP00000075787	99.1004	98.9505
ENSG00000091127	homo_sapiens	ENSP00000417402	99.5461	99.0923	gorilla_gorilla	ENSGGOP00000011609	99.5461	99.0923
ENSG00000091127	homo_sapiens	ENSP00000417402	89.5613	83.056	ornithorhynchus_anatinus	ENSOANP00000037052	78.3069	72.619
ENSG00000091127	homo_sapiens	ENSP00000417402	91.9818	85.3253	sarcophilus_harrisii	ENSSHAP00000032632	91.7044	85.0679
ENSG00000091127	homo_sapiens	ENSP00000417402	65.8094	59.3041	notamacropus_eugenii	ENSMEUP00000013741	70.6169	63.6364
ENSG00000091127	homo_sapiens	ENSP00000417402	67.7761	63.3888	choloepus_hoffmanni	ENSCHOP00000009803	68.0851	63.6778

Showing 1 to 10 of 205 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005634	is_active_in nucleus	3	IBA,IDA	Homo_sapiens(9606)	Component
GO:0009982	enables pseudouridine synthase activity	3	IBA,IDA,IMP	Homo_sapiens(9606)	Function
GO:0017148	involved_in negative regulation of translation	2	IDA,IMP	Homo_sapiens(9606)	Process
GO:1990481	involved_in mRNA pseudouridine synthesis	2	IDA,IMP	Homo_sapiens(9606)	Process
GO:0001522	involved_in pseudouridine synthesis	1	IBA	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0006397	involved_in mRNA processing	1	IEA	Homo_sapiens(9606)	Process
GO:0008380	involved_in RNA splicing	1	IEA	Homo_sapiens(9606)	Process
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0031119	involved_in tRNA pseudouridine synthesis	1	IDA	Homo_sapiens(9606)	Process

Showing 1 to 10 of 12 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression