Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000089248 Gene ID 10961 Accession 13799
Symbol ERP29 Alias ERp28;ERp31;PDIA9;PDI-DB;C12orf8;HEL-S-107 Full Name endoplasmic reticulum protein 29
Status Confidence Length 10102 bases Strand Plus strand
Position 12 : 112013348 - 112023449 RNA binding domain N.A.
Summary This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ERP29-202 ENST00000455836 1333 53aa ENSP00000412083
ERP29-201 ENST00000261735 1623 261aa ENSP00000261735
ERP29-205 ENST00000553161 916 No protein -
ERP29-204 ENST00000552052 284 95aa ENSP00000447472
ERP29-203 ENST00000546477 1698 160aa ENSP00000449018

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000089248

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000089248homo_sapiensENSP0000026173598.850698.8506nomascus_leucogenysENSNLEP0000000003698.850698.8506
ENSG00000089248homo_sapiensENSP0000026173599.616999.6169pan_paniscusENSPPAP0000003822999.616999.6169
ENSG00000089248homo_sapiensENSP0000026173598.850698.8506pongo_abeliiENSPPYP0000002806798.850698.8506
ENSG00000089248homo_sapiensENSP0000026173599.616999.6169pan_troglodytesENSPTRP0000000928299.616999.6169
ENSG00000089248homo_sapiensENSP0000026173599.233798.8506gorilla_gorillaENSGGOP0000004702785.761685.4305
ENSG00000089248homo_sapiensENSP0000026173585.440676.2452ornithorhynchus_anatinusENSOANP0000000759881.386972.6277
ENSG00000089248homo_sapiensENSP0000026173552.873645.5939sarcophilus_harrisiiENSSHAP0000001126686.2574.375
ENSG00000089248homo_sapiensENSP0000026173581.992372.7969notamacropus_eugeniiENSMEUP0000000412481.679472.5191
ENSG00000089248homo_sapiensENSP0000026173593.103488.5057dasypus_novemcinctusENSDNOP0000000383993.103488.5057
ENSG00000089248homo_sapiensENSP0000026173593.869788.5057erinaceus_europaeusENSEEUP0000001110194.230888.8462
ENSG00000089248homo_sapiensENSP0000026173591.187783.908echinops_telfairiENSETEP0000001237390.839783.5878
ENSG00000089248homo_sapiensENSP0000026173598.467496.5517callithrix_jacchusENSCJAP0000006038198.467496.5517
ENSG00000089248homo_sapiensENSP0000026173597.701196.9349cercocebus_atysENSCATP0000001669097.701196.9349
ENSG00000089248homo_sapiensENSP0000026173598.467497.7011macaca_fascicularisENSMFAP0000001048198.467497.7011
ENSG00000089248homo_sapiensENSP0000026173596.934995.7854macaca_fascicularisENSMFAP0000001050198.06296.8992
ENSG00000089248homo_sapiensENSP0000026173598.467497.7011macaca_mulattaENSMMUP0000008115598.467497.7011
ENSG00000089248homo_sapiensENSP0000026173598.467497.7011macaca_mulattaENSMMUP0000006749198.467497.7011
ENSG00000089248homo_sapiensENSP0000026173598.467497.7011macaca_nemestrinaENSMNEP0000000375698.467497.7011
ENSG00000089248homo_sapiensENSP0000026173598.084396.9349papio_anubisENSPANP0000001117098.084396.9349
ENSG00000089248homo_sapiensENSP0000026173596.934996.1686mandrillus_leucophaeusENSMLEP0000000440496.934996.1686
ENSG00000089248homo_sapiensENSP0000026173597.701196.5517mandrillus_leucophaeusENSMLEP0000000206297.701196.5517
ENSG00000089248homo_sapiensENSP0000026173595.402392.3372tursiops_truncatusENSTTRP0000001022995.402392.3372
ENSG00000089248homo_sapiensENSP0000026173595.402391.954vulpes_vulpesENSVVUP0000001778795.402391.954
ENSG00000089248homo_sapiensENSP0000026173592.337288.5057mus_spretusMGP_SPRETEiJ_P007311791.984788.1679
ENSG00000089248homo_sapiensENSP0000026173592.720389.272equus_asinusENSEASP0000503774394.90291.3726
ENSG00000089248homo_sapiensENSP0000026173593.869790.8046capra_hircusENSCHIP0000000967991.078188.1041
ENSG00000089248homo_sapiensENSP0000026173592.720389.272loxodonta_africanaENSLAFP0000002348292.366488.9313
ENSG00000089248homo_sapiensENSP0000026173596.934993.1034panthera_leoENSPLOP0000000820596.934993.1034
ENSG00000089248homo_sapiensENSP0000026173595.019291.5709ailuropoda_melanoleucaENSAMEP0000000878895.019291.5709
ENSG00000089248homo_sapiensENSP0000026173593.486689.6552bos_indicus_hybridENSBIXP0000502486994.573690.6977
ENSG00000089248homo_sapiensENSP0000026173596.551793.1034oryctolagus_cuniculusENSOCUP0000000624096.551793.1034
ENSG00000089248homo_sapiensENSP0000026173595.402391.5709equus_caballusENSECAP0000006469673.020570.088
ENSG00000089248homo_sapiensENSP0000026173595.785492.7203canis_lupus_familiarisENSCAFP0084502746495.785492.7203
ENSG00000089248homo_sapiensENSP0000026173596.934993.1034panthera_pardusENSPPRP0000001990596.934993.1034
ENSG00000089248homo_sapiensENSP0000026173560.153351.341panthera_pardusENSPPRP0000000273167.09457.265
ENSG00000089248homo_sapiensENSP0000026173594.63691.1877marmota_marmota_marmotaENSMMMP0000000593594.63691.1877
ENSG00000089248homo_sapiensENSP0000026173595.019291.1877balaenoptera_musculusENSBMSP0001001191795.019291.1877
ENSG00000089248homo_sapiensENSP0000026173596.551792.3372cavia_porcellusENSCPOP0000000945296.551792.3372
ENSG00000089248homo_sapiensENSP0000026173573.180164.751felis_catusENSFCAP0000002289655.362348.9855
ENSG00000089248homo_sapiensENSP0000026173595.402391.5709ursus_americanusENSUAMP0000001136995.402391.5709
ENSG00000089248homo_sapiensENSP0000026173581.226169.7318monodelphis_domesticaENSMODP000000034848068.6792
ENSG00000089248homo_sapiensENSP0000026173558.620755.5556bison_bison_bisonENSBBBP0000000437595.62590.625
ENSG00000089248homo_sapiensENSP0000026173594.63691.5709monodon_monocerosENSMMNP0001501597494.63691.5709
ENSG00000089248homo_sapiensENSP0000026173594.63690.4215sus_scrofaENSSSCP0000001055594.63690.4215
ENSG00000089248homo_sapiensENSP0000026173545.593941.3793microcebus_murinusENSMICP0000003562377.777870.5882
ENSG00000089248homo_sapiensENSP0000026173595.785492.7203microcebus_murinusENSMICP0000001686196.153893.0769
ENSG00000089248homo_sapiensENSP0000026173594.63691.1877jaculus_jaculusENSJJAP0000000871796.484492.9688
ENSG00000089248homo_sapiensENSP0000026173593.869790.4215ovis_aries_rambouilletENSOARP0002002542494.594691.1197
ENSG00000089248homo_sapiensENSP0000026173595.402391.5709ursus_maritimusENSUMAP0000001121995.402391.5709
ENSG00000089248homo_sapiensENSP0000026173560.536457.8544ochotona_princepsENSOPRP0000000475095.180790.9639
ENSG00000089248homo_sapiensENSP0000026173594.63691.5709delphinapterus_leucasENSDLEP0000002721794.63691.5709
ENSG00000089248homo_sapiensENSP0000026173594.63691.5709physeter_catodonENSPCTP0000501459794.63691.5709
ENSG00000089248homo_sapiensENSP0000026173593.103490.0383mus_caroliMGP_CAROLIEiJ_P007043392.748189.6947
ENSG00000089248homo_sapiensENSP0000026173591.95488.5057mus_musculusENSMUSP0000011734791.603188.1679
ENSG00000089248homo_sapiensENSP0000026173575.478969.3487dipodomys_ordiiENSDORP0000002683683.122476.3713
ENSG00000089248homo_sapiensENSP0000026173579.693574.3295dipodomys_ordiiENSDORP0000001714388.510682.5532
ENSG00000089248homo_sapiensENSP0000026173592.337287.3563dipodomys_ordiiENSDORP0000002140782.252677.8157
ENSG00000089248homo_sapiensENSP0000026173596.551792.7203mustela_putorius_furoENSMPUP0000000230296.923193.0769
ENSG00000089248homo_sapiensENSP0000026173598.084396.9349aotus_nancymaaeENSANAP0000003253698.084396.9349
ENSG00000089248homo_sapiensENSP0000026173598.850697.318saimiri_boliviensis_boliviensisENSSBOP0000000035898.850697.318
ENSG00000089248homo_sapiensENSP0000026173595.402390.4215vicugna_pacosENSVPAP0000000650595.402390.4215
ENSG00000089248homo_sapiensENSP0000026173598.467497.318chlorocebus_sabaeusENSCSAP0000001552398.467497.318
ENSG00000089248homo_sapiensENSP0000026173595.019289.6552mesocricetus_auratusENSMAUP0000001745395.384690
ENSG00000089248homo_sapiensENSP0000026173595.402392.3372phocoena_sinusENSPSNP0000001071595.402392.3372
ENSG00000089248homo_sapiensENSP0000026173595.785491.1877camelus_dromedariusENSCDRP0000502927995.785491.1877
ENSG00000089248homo_sapiensENSP0000026173597.31895.0192carlito_syrichtaENSTSYP0000002776997.31895.0192
ENSG00000089248homo_sapiensENSP0000026173593.103489.6552panthera_tigris_altaicaENSPTIP0000002420697.293.6
ENSG00000089248homo_sapiensENSP0000026173593.869790.0383rattus_norvegicusENSRNOP0000000182294.230890.3846
ENSG00000089248homo_sapiensENSP0000026173595.785492.3372prolemur_simusENSPSMP0000003753696.153892.6923
ENSG00000089248homo_sapiensENSP0000026173595.019290.0383microtus_ochrogasterENSMOCP0000001390595.384690.3846
ENSG00000089248homo_sapiensENSP0000026173592.337288.1226sorex_araneusENSSARP0000001030092.692388.4615
ENSG00000089248homo_sapiensENSP0000026173594.63690.8046peromyscus_maniculatus_bairdiiENSPEMP000000167479591.1538
ENSG00000089248homo_sapiensENSP0000026173593.486689.6552bos_mutusENSBMUP0000000960894.208590.3475
ENSG00000089248homo_sapiensENSP0000026173592.720388.5057mus_spicilegusENSMSIP0000001248292.366488.1679
ENSG00000089248homo_sapiensENSP0000026173593.486688.5057cricetulus_griseus_chok1gshdENSCGRP0000100278793.846288.8462
ENSG00000089248homo_sapiensENSP0000026173595.402391.954pteropus_vampyrusENSPVAP0000001168995.402391.954
ENSG00000089248homo_sapiensENSP0000026173594.252990.0383myotis_lucifugusENSMLUP0000002027593.893189.6947
ENSG00000089248homo_sapiensENSP0000026173582.758672.7969vombatus_ursinusENSVURP000100046217565.9722
ENSG00000089248homo_sapiensENSP0000026173593.869791.1877rhinolophus_ferrumequinumENSRFEP0001001425993.869791.1877
ENSG00000089248homo_sapiensENSP0000026173596.168692.7203neovison_visonENSNVIP0000002070296.538593.0769
ENSG00000089248homo_sapiensENSP0000026173593.486689.6552bos_taurusENSBTAP0000000875494.573690.6977
ENSG00000089248homo_sapiensENSP0000026173595.402393.1034heterocephalus_glaber_femaleENSHGLP0000002006795.402393.1034
ENSG00000089248homo_sapiensENSP0000026173599.233798.0843rhinopithecus_bietiENSRBIP0000002140399.233798.0843
ENSG00000089248homo_sapiensENSP0000026173595.785492.7203canis_lupus_dingoENSCAFP0002002160795.785492.7203
ENSG00000089248homo_sapiensENSP0000026173594.63691.5709sciurus_vulgarisENSSVLP0000500715094.63691.5709
ENSG00000089248homo_sapiensENSP0000026173582.375573.1801phascolarctos_cinereusENSPCIP0000005339081.132172.0755
ENSG00000089248homo_sapiensENSP0000026173591.95487.3563procavia_capensisENSPCAP0000001341592.307787.6923
ENSG00000089248homo_sapiensENSP0000026173595.785492.3372nannospalax_galiliENSNGAP0000001934895.785492.3372
ENSG00000089248homo_sapiensENSP0000026173593.486689.6552bos_grunniensENSBGRP0000004159294.208590.3475
ENSG00000089248homo_sapiensENSP0000026173595.402391.1877chinchilla_lanigeraENSCLAP0000001983195.402391.1877
ENSG00000089248homo_sapiensENSP0000026173593.869790.4215cervus_hanglu_yarkandensisENSCHYP0000000599594.594691.1197
ENSG00000089248homo_sapiensENSP0000026173593.869790.4215catagonus_wagneriENSCWAP0000002111493.869790.4215
ENSG00000089248homo_sapiensENSP0000026173594.63690.8046ictidomys_tridecemlineatusENSSTOP0000001634594.63690.8046
ENSG00000089248homo_sapiensENSP0000026173590.421587.7395otolemur_garnettiiENSOGAP0000002152497.119394.2387
ENSG00000089248homo_sapiensENSP0000026173598.467496.9349cebus_imitatorENSCCAP0000002973498.467496.9349
ENSG00000089248homo_sapiensENSP0000026173593.869790.4215urocitellus_parryiiENSUPAP0001000873193.869790.4215
ENSG00000089248homo_sapiensENSP0000026173593.869790.0383moschus_moschiferusENSMMSP0000002233294.594690.7336
ENSG00000089248homo_sapiensENSP0000026173599.233798.0843rhinopithecus_roxellanaENSRROP0000003994399.233798.0843
ENSG00000089248homo_sapiensENSP0000026173593.869789.6552mus_pahariMGP_PahariEiJ_P005864093.869789.6552
ENSG00000089248homo_sapiensENSP0000026173578.927275.0958propithecus_coquereliENSPCOP0000002893085.477281.3278
ENSG00000089248homo_sapiensENSP0000026173596.934993.4866propithecus_coquereliENSPCOP0000003020897.307793.8462
ENSG00000089248homo_sapiensENSP0000026173552.107328.7356drosophila_melanogasterFBpp030941252.918329.1829
ENSG00000089248homo_sapiensENSP0000026173563.601547.1264callorhinchus_miliiENSCMIP0000003917462.40646.2406
ENSG00000089248homo_sapiensENSP0000026173572.796956.705latimeria_chalumnaeENSLACP0000001213973.9357.5875
ENSG00000089248homo_sapiensENSP0000026173571.647556.3218xenopus_tropicalisENSXETP0000000936166.312152.1277
ENSG00000089248homo_sapiensENSP0000026173581.226169.3487chrysemys_picta_belliiENSCPBP0000000461782.812570.7031
ENSG00000089248homo_sapiensENSP0000026173570.114959.7701sphenodon_punctatusENSSPUP0000001316383.181870.9091
ENSG00000089248homo_sapiensENSP0000026173571.647560.1533crocodylus_porosusENSCPRP0000502097773.046961.3281
ENSG00000089248homo_sapiensENSP0000026173580.459867.433laticauda_laticaudataENSLLTP0000000080979.545566.6667
ENSG00000089248homo_sapiensENSP0000026173578.927265.5172notechis_scutatusENSNSUP0000001641278.030364.7727
ENSG00000089248homo_sapiensENSP0000026173580.842968.1992pseudonaja_textilisENSPTXP0000002549279.924267.4242
ENSG00000089248homo_sapiensENSP0000026173578.927267.0498anas_platyrhynchos_platyrhynchosENSAPLP0000000819678.927267.0498
ENSG00000089248homo_sapiensENSP0000026173578.544167.8161gallus_gallusENSGALP0001003903381.349270.2381
ENSG00000089248homo_sapiensENSP0000026173573.946461.6858meleagris_gallopavoENSMGAP0000003321976.284663.6364
ENSG00000089248homo_sapiensENSP0000026173580.842969.7318serinus_canariaENSSCAP0000001085651.842844.7174
ENSG00000089248homo_sapiensENSP0000026173579.310368.1992parus_majorENSPMJP0000000544980.544769.2607
ENSG00000089248homo_sapiensENSP0000026173578.160964.751anolis_carolinensisENSACAP0000000918880.632466.7984
ENSG00000089248homo_sapiensENSP0000026173580.076667.433naja_najaENSNNAP0000002744378.571466.1654
ENSG00000089248homo_sapiensENSP0000026173578.544165.1341podarcis_muralisENSPMRP0000001499778.244364.8855
ENSG00000089248homo_sapiensENSP0000026173568.199258.6207geospiza_fortisENSGFOP0000001245883.177671.4953
ENSG00000089248homo_sapiensENSP0000026173578.927268.5824taeniopygia_guttataENSTGUP0000002187581.422970.751
ENSG00000089248homo_sapiensENSP0000026173560.919546.7433erpetoichthys_calabaricusENSECRP0000003128265.163950
ENSG00000089248homo_sapiensENSP0000026173549.042137.1647erpetoichthys_calabaricusENSECRP0000003123456.140442.5439
ENSG00000089248homo_sapiensENSP0000026173579.310364.3678salvator_merianaeENSSMRP0000001182876.951762.4535
ENSG00000089248homo_sapiensENSP0000026173581.226167.8161pelodiscus_sinensisENSPSIP0000000364183.137369.4118
ENSG00000089248homo_sapiensENSP0000026173581.226168.5824gopherus_evgoodeiENSGEVP0000502850382.812569.9219
ENSG00000089248homo_sapiensENSP0000026173581.609268.9655chelonoidis_abingdoniiENSCABP0000002200983.203170.3125
ENSG00000089248homo_sapiensENSP0000026173550.191642.1456struthio_camelus_australisENSSCUP0000000234481.87568.75
ENSG00000089248homo_sapiensENSP0000026173578.927267.433strigops_habroptilaENSSHBP0000501008081.422969.5652
ENSG00000089248homo_sapiensENSP0000026173582.758670.4981terrapene_carolina_triunguisENSTMTP0000003136184.37571.875
ENSG00000089248homo_sapiensENSP0000026173578.544167.0498aquila_chrysaetos_chrysaetosENSACCP0002000596881.027769.17
ENSG00000089248homo_sapiensENSP0000026173549.425342.1456ficedula_albicollisENSFALP0000000937680.62568.75
ENSG00000089248homo_sapiensENSP0000026173578.544167.0498coturnix_japonicaENSCJPP0000500770881.349269.4444
ENSG00000089248homo_sapiensENSP0000026173568.965555.9387leptobrachium_leishanenseENSLLEP0000001486169.230856.1538

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001934involved_in positive regulation of protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0003756NOT enables protein disulfide isomerase activity1IKRHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005783is_active_in endoplasmic reticulum2IBA,IDAHomo_sapiens(9606)Component
GO:0005788located_in endoplasmic reticulum lumen1NASHomo_sapiens(9606)Component
GO:0005790located_in smooth endoplasmic reticulum1ISSHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1NASHomo_sapiens(9606)Process
GO:0006886involved_in intracellular protein transport1NASHomo_sapiens(9606)Process
GO:0009306involved_in protein secretion1IEAHomo_sapiens(9606)Process
GO:0009986located_in cell surface1IDAHomo_sapiens(9606)Component
GO:0010628involved_in positive regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0010629involved_in negative regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0030133located_in transport vesicle1ISSHomo_sapiens(9606)Component
GO:0042470located_in melanosome1IEAHomo_sapiens(9606)Component
GO:0042803enables protein homodimerization activity1IEAHomo_sapiens(9606)Function
GO:0043335involved_in protein unfolding1NASHomo_sapiens(9606)Process
GO:0043406acts_upstream_of_or_within positive regulation of MAP kinase activity1IDAHomo_sapiens(9606)Process
GO:0050709involved_in negative regulation of protein secretion1IDAHomo_sapiens(9606)Process
GO:0051087enables protein-folding chaperone binding1ISSHomo_sapiens(9606)Function
GO:1902235involved_in regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway1IEAHomo_sapiens(9606)Process

Expression