RBPWorld - a comprehensive database of RNA Binding Proteins

Welcome to

RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	FlavivirusesSARS-COV-2DengueZika
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq

Description

Ensembl ID	ENSG00000087302	Gene ID	51637	Accession	23169
Symbol	RTRAF	Alias	CLE;CLE7;hCLE;CGI99;RLLM1;hCLE1;CGI-99;LCRP369;C14orf166	Full Name	RNA transcription, translation and transport factor
Status	Confidence	Length	21181 bases	Strand	Plus strand
Position	14 : 51989514 - 52010694	RNA binding domain	N.A.
Summary	Enables RNA binding activity; RNA polymerase II complex binding activity; and identical protein binding activity. Involved in negative regulation of protein kinase activity; positive regulation of transcription by RNA polymerase II; and tRNA splicing, via endonucleolytic cleavage and ligation. Located in microtubule cytoskeleton; nucleoplasm; and perinuclear region of cytoplasm. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
RTRAF-201	ENST00000261700	7007	244aa	ENSP00000261700
RTRAF-207	ENST00000557553	557	68aa	ENSP00000451751
RTRAF-206	ENST00000556760	851	193aa	ENSP00000451715
RTRAF-202	ENST00000553362	683	129aa	ENSP00000451153
RTRAF-204	ENST00000553707	822	No protein	-
RTRAF-205	ENST00000555319	578	No protein	-
RTRAF-203	ENST00000553479	562	No protein	-

Gene Model

Click here to download ENSG00000087302's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000087302's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000993	enables RNA polymerase II complex binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	3	HDA,IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0005813	located_in centrosome	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IEA	Homo_sapiens(9606)	Component
GO:0006388	involved_in tRNA splicing, via endonucleolytic cleavage and ligation	3	IBA,IMP,NAS	Homo_sapiens(9606)	Process
GO:0006469	involved_in negative regulation of protein kinase activity	1	IMP	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0045944	involved_in positive regulation of transcription by RNA polymerase II	1	IMP	Homo_sapiens(9606)	Process
GO:0048471	located_in perinuclear region of cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0050658	involved_in RNA transport	1	TAS	Homo_sapiens(9606)	Process
GO:0072669	part_of tRNA-splicing ligase complex	3	IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0072686	located_in mitotic spindle	1	IDA	Homo_sapiens(9606)	Component

Expression