RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000083720	Gene ID	5019	Accession	8527
Symbol	OXCT1	Alias	OXCT;SCOT	Full Name	3-oxoacid CoA-transferase 1
Status	Confidence	Length	140361 bases	Strand	Minus strand
Position	5 : 41730065 - 41870425	RNA binding domain	N.A.
Summary	This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
OXCT1-201	ENST00000196371	3294	520aa	ENSP00000196371
OXCT1-206	ENST00000512084	1593	123aa	ENSP00000421143
OXCT1-205	ENST00000510634	1441	123aa	ENSP00000423144
OXCT1-204	ENST00000509987	1441	334aa	ENSP00000425348
OXCT1-203	ENST00000508557	596	No protein	-
OXCT1-202	ENST00000503374	364	No protein	-
OXCT1-207	ENST00000513081	350	No protein	-
OXCT1-208	ENST00000514723	241	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
9771	Echocardiography	1.10366259186344E-6	17903301
50455	Child Development Disorders, Pervasive	2.5898000E-005	-
54809	Insulin-Like Growth Factor I	2.8740000E-005	-
54835	Insulin-Like Growth Factor I	2.0980000E-005	-
54840	Insulin-Like Growth Factor I	2.9520000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005739	is_active_in mitochondrion	3	IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0005759	located_in mitochondrial matrix	1	TAS	Homo_sapiens(9606)	Component
GO:0008260	enables succinyl-CoA:3-oxo-acid CoA-transferase activity	2	IBA,IMP	Homo_sapiens(9606)	Function
GO:0042182	involved_in ketone catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0046950	involved_in cellular ketone body metabolic process	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0046952	involved_in ketone body catabolic process	1	IEA	Homo_sapiens(9606)	Process