Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000082781 Gene ID 3693 Accession 6160
Symbol ITGB5 Alias NA Full Name integrin subunit beta 5
Status Confidence Length 139471 bases Strand Minus strand
Position 3 : 124761948 - 124901418 RNA binding domain N.A.
Summary This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ITGB5-201 ENST00000296181 4440 799aa ENSP00000296181
ITGB5-202 ENST00000460797 2228 No protein -
ITGB5-203 ENST00000461306 577 No protein -
ITGB5-207 ENST00000481591 1202 401aa ENSP00000420814
ITGB5-209 ENST00000488466 971 323aa ENSP00000477446
ITGB5-205 ENST00000474838 475 No protein -
ITGB5-210 ENST00000496703 789 263aa ENSP00000418367
ITGB5-206 ENST00000476988 492 No protein -
ITGB5-204 ENST00000465464 1164 40aa ENSP00000418079
ITGB5-212 ENST00000608657 825 139aa ENSP00000477230
ITGB5-208 ENST00000483168 576 79aa ENSP00000419198
ITGB5-211 ENST00000608107 548 59aa ENSP00000476655
ITGB5-213 ENST00000608945 267 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001618enables virus receptor activity1IEAHomo_sapiens(9606)Function
GO:0005178enables integrin binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005886located_in plasma membrane1TASHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion2HDA,IBAHomo_sapiens(9606)Component
GO:0007160involved_in cell-matrix adhesion2IBA,IMPHomo_sapiens(9606)Process
GO:0007179involved_in transforming growth factor beta receptor signaling pathway1IMPHomo_sapiens(9606)Process
GO:0007229involved_in integrin-mediated signaling pathway2IBA,IMPHomo_sapiens(9606)Process
GO:0008305part_of integrin complex1IBAHomo_sapiens(9606)Component
GO:0009986located_in cell surface3HDA,IBA,IDAHomo_sapiens(9606)Component
GO:0016477involved_in cell migration2IBA,IMPHomo_sapiens(9606)Process
GO:0033627involved_in cell adhesion mediated by integrin1IBAHomo_sapiens(9606)Process
GO:0034684part_of integrin alphav-beta5 complex1IDAHomo_sapiens(9606)Component
GO:0035987involved_in endodermal cell differentiation1IEPHomo_sapiens(9606)Process
GO:0043149involved_in stress fiber assembly1IMPHomo_sapiens(9606)Process
GO:0043235part_of receptor complex1IDAHomo_sapiens(9606)Component
GO:0045335located_in phagocytic vesicle1TASHomo_sapiens(9606)Component
GO:0046718involved_in viral entry into host cell1IEAHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0090136involved_in epithelial cell-cell adhesion1IMPHomo_sapiens(9606)Process

Expression