RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000079739	Gene ID	5236	Accession	8905
Symbol	PGM1	Alias	CDG1T;GSD14	Full Name	phosphoglucomutase 1
Status	Confidence	Length	66835 bases	Strand	Plus strand
Position	1 : 63593411 - 63660245	RNA binding domain	N.A.
Summary	The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
31665645	Systematic Discovery of Endogenous Human Ribonucleoprotein Complexes.	L Anna Mallam	2019-10-29	Cell reports

Name	Transcript ID	bp	Protein	Translation ID
PGM1-202	ENST00000371084	2337	562aa	ENSP00000360125
PGM1-206	ENST00000650546	2423	584aa	ENSP00000497812
PGM1-203	ENST00000473117	373	No protein	-
PGM1-201	ENST00000371083	2657	580aa	ENSP00000360124
PGM1-204	ENST00000483707	612	No protein	-
PGM1-205	ENST00000540265	2345	365aa	ENSP00000443449

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
4638	Cholesterol	1.08750826576591E-5	17903299
12162	Inflammatory Bowel Diseases	1.226E-5	17068223
13090	Bipolar Disorder	9.59E-5	19488044
18745	Erythrocyte Indices	5.206e-005	-
23379	Body Height	7.5000000E-005	-
27942	Diabetes Mellitus	2.0930000E-006	-
38686	Platelet Function Tests	1.1030600E-005	-
38918	Platelet Function Tests	1.4690200E-005	-
40475	Platelet Function Tests	1.3256800E-005	-
52018	Child Development Disorders, Pervasive	4.6000000E-005	-
61035	Alcohol Drinking	2E-9	21665994
63886	Bronchodilator Agents	4E-6	26634245
63887	Lung Volume Measurements	4E-6	26634245
86267	Diabetes Mellitus, Type 1	4E-7	19430480

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000287	enables magnesium ion binding	1	IDA	Homo_sapiens(9606)	Function
GO:0004614	enables phosphoglucomutase activity	3	IBA,IDA,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	NAS	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	2	IBA,TAS	Homo_sapiens(9606)	Component
GO:0005975	involved_in carbohydrate metabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0006006	involved_in glucose metabolic process	2	IDA,NAS	Homo_sapiens(9606)	Process
GO:0006094	involved_in gluconeogenesis	1	TAS	Homo_sapiens(9606)	Process
GO:0006096	involved_in glycolytic process	1	TAS	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:1904724	located_in tertiary granule lumen	1	TAS	Homo_sapiens(9606)	Component
GO:1904813	located_in ficolin-1-rich granule lumen	1	TAS	Homo_sapiens(9606)	Component