RBP Type
Non-canonical_RBPs
Diseases
Disease
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000076716 Gene ID
2239
Accession
4452
Symbol
GPC4
Alias
KPTS;K-glypican
Full Name
glypican 4
Status
Confidence
Length
115387 bases
Strand
Minus strand
Position
X : 133300103 - 133415489
RNA binding domain
N.A.
Summary
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
GPC4-201
ENST00000370828
4959
556aa
ENSP00000359864
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
2127 Body Mass Index 4.25827720586365E-5 17903300 2131 Body Mass Index 4.2582772058708E-5 17903300 2408 Body Mass Index 7.15715792974654E-5 17903300 2409 Body Mass Index 7.15715792973803E-5 17903300 2421 Body Mass Index 9.7391619140625E-5 17903300 2423 Body Mass Index 9.73916191406854E-5 17903300
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 HDA Homo_sapiens(9606) Component GO:0005796 located_in Golgi lumen 1 TAS Homo_sapiens(9606) Component GO:0005886 located_in plasma membrane 1 TAS Homo_sapiens(9606) Component GO:0009897 located_in external side of plasma membrane 1 IDA Homo_sapiens(9606) Component GO:0009966 involved_in regulation of signal transduction 1 IEA Homo_sapiens(9606) Process GO:0009986 is_active_in cell surface 1 IBA Homo_sapiens(9606) Component GO:0016055 involved_in Wnt signaling pathway 1 IMP Homo_sapiens(9606) Process GO:0016477 involved_in cell migration 1 IBA Homo_sapiens(9606) Process GO:0043202 located_in lysosomal lumen 1 TAS Homo_sapiens(9606) Component GO:0045202 is_active_in synapse 1 IBA Homo_sapiens(9606) Component GO:0060071 involved_in Wnt signaling pathway, planar cell polarity pathway 1 IEA Homo_sapiens(9606) Process GO:0062023 located_in collagen-containing extracellular matrix 1 IEA Homo_sapiens(9606) Component GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:0098696 involved_in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane 1 IBA Homo_sapiens(9606) Process GO:0098978 located_in glutamatergic synapse 1 IEA Homo_sapiens(9606) Component GO:0099560 involved_in synaptic membrane adhesion 1 IBA Homo_sapiens(9606) Process GO:1904929 enables coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway 1 NAS Homo_sapiens(9606) Function GO:1905606 involved_in regulation of presynapse assembly 1 IBA Homo_sapiens(9606) Process
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