Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000075618 Gene ID 6624 Accession 11148
Symbol FSCN1 Alias HSN;SNL;p55;FAN1 Full Name fascin actin-bundling protein 1
Status Confidence Length 13840 bases Strand Plus strand
Position 7 : 5592816 - 5606655 RNA binding domain N.A.
Summary This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
33614909 Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target? Hongliang Liu 2021-03-26 Molecular therapy oncolytics

Transcripts

Name Transcript ID bp Protein Translation ID
FSCN1-201 ENST00000382361 2784 493aa ENSP00000371798
FSCN1-203 ENST00000444748 580 132aa ENSP00000404506
FSCN1-204 ENST00000447103 713 120aa ENSP00000409967
FSCN1-202 ENST00000405801 550 137aa ENSP00000383982
FSCN1-205 ENST00000473330 2215 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000075618homo_sapiensENSP0000038871673.170756.9106homo_sapiensENSP0000037179873.022356.7951
ENSG00000075618homo_sapiensENSP0000026582542.570327.1084homo_sapiensENSP0000037179843.00227.3834

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000075618homo_sapiensENSP0000037179852.332751.3185nomascus_leucogenysENSNLEP0000002452994.160692.3358
ENSG00000075618homo_sapiensENSP0000037179855.375354.9696pan_paniscusENSPPAP0000003741186.392485.7595
ENSG00000075618homo_sapiensENSP0000037179897.565996.5517pongo_abeliiENSPPYP0000004377397.963396.945
ENSG00000075618homo_sapiensENSP00000371798100100pan_troglodytesENSPTRP00000032261100100
ENSG00000075618homo_sapiensENSP00000371798100100pan_troglodytesENSPTRP00000065191100100
ENSG00000075618homo_sapiensENSP0000037179899.797299.7972gorilla_gorillaENSGGOP0000001883499.797299.7972
ENSG00000075618homo_sapiensENSP0000037179892.292183.1643ornithorhynchus_anatinusENSOANP0000003234891.919282.8283
ENSG00000075618homo_sapiensENSP0000037179894.523387.8296sarcophilus_harrisiiENSSHAP0000000404494.523387.8296
ENSG00000075618homo_sapiensENSP0000037179873.833769.3712notamacropus_eugeniiENSMEUP0000000768384.454879.3503
ENSG00000075618homo_sapiensENSP0000037179899.594398.9858callithrix_jacchusENSCJAP0000001697999.594398.9858
ENSG00000075618homo_sapiensENSP0000037179899.797299.5943cercocebus_atysENSCATP0000002376799.797299.5943
ENSG00000075618homo_sapiensENSP0000037179895.334794.3205macaca_fascicularisENSMFAP0000005888392.702291.716
ENSG00000075618homo_sapiensENSP0000037179899.594399.3915macaca_mulattaENSMMUP0000003551999.594399.3915
ENSG00000075618homo_sapiensENSP0000037179899.594399.3915macaca_nemestrinaENSMNEP0000001742199.594399.3915
ENSG00000075618homo_sapiensENSP0000037179899.797299.5943papio_anubisENSPANP0000005530599.797299.5943
ENSG00000075618homo_sapiensENSP0000037179885.801285.5984mandrillus_leucophaeusENSMLEP0000001534399.764299.5283
ENSG00000075618homo_sapiensENSP0000037179884.178582.5558tursiops_truncatusENSTTRP0000001018096.287794.4316
ENSG00000075618homo_sapiensENSP0000037179899.594398.1744vulpes_vulpesENSVVUP0000000844899.594398.1744
ENSG00000075618homo_sapiensENSP0000037179898.78396.5517mus_spretusMGP_SPRETEiJ_P007476898.78396.5517
ENSG00000075618homo_sapiensENSP0000037179898.174496.5517equus_asinusENSEASP0000500001898.174496.5517
ENSG00000075618homo_sapiensENSP0000037179896.348993.3063capra_hircusENSCHIP0000001155596.348993.3063
ENSG00000075618homo_sapiensENSP0000037179890.872287.6268loxodonta_africanaENSLAFP0000002137990.505187.2727
ENSG00000075618homo_sapiensENSP0000037179898.985897.5659panthera_leoENSPLOP0000002112798.985897.5659
ENSG00000075618homo_sapiensENSP0000037179899.391597.7688ailuropoda_melanoleucaENSAMEP0000000697899.391597.7688
ENSG00000075618homo_sapiensENSP0000037179896.14693.1034bos_indicus_hybridENSBIXP0000501279396.14693.1034
ENSG00000075618homo_sapiensENSP0000037179847.870245.2333oryctolagus_cuniculusENSOCUP0000003300071.515267.5758
ENSG00000075618homo_sapiensENSP0000037179894.92992.9006equus_caballusENSECAP0000004272192.857190.873
ENSG00000075618homo_sapiensENSP0000037179899.594398.1744canis_lupus_familiarisENSCAFP0084501873599.594398.1744
ENSG00000075618homo_sapiensENSP0000037179898.985897.5659panthera_pardusENSPPRP0000000954798.985897.5659
ENSG00000075618homo_sapiensENSP0000037179849.492943.2049balaenoptera_musculusENSBMSP0001001245777.70767.8344
ENSG00000075618homo_sapiensENSP0000037179896.957493.9148balaenoptera_musculusENSBMSP0001002420996.957493.9148
ENSG00000075618homo_sapiensENSP0000037179898.985897.3631cavia_porcellusENSCPOP0000000721198.985897.3631
ENSG00000075618homo_sapiensENSP0000037179897.363195.1318felis_catusENSFCAP0000000836492.664190.5405
ENSG00000075618homo_sapiensENSP0000037179887.221186.4097ursus_americanusENSUAMP0000003074899.76898.8399
ENSG00000075618homo_sapiensENSP0000037179894.523388.2353monodelphis_domesticaENSMODP0000000122294.33288.0567
ENSG00000075618homo_sapiensENSP0000037179876.876374.0365bison_bison_bisonENSBBBP0000001744176.876374.0365
ENSG00000075618homo_sapiensENSP0000037179896.957494.1176monodon_monocerosENSMMNP0001500595096.957494.1176
ENSG00000075618homo_sapiensENSP0000037179896.551793.3063sus_scrofaENSSSCP0000002456796.551793.3063
ENSG00000075618homo_sapiensENSP0000037179898.985897.3631microcebus_murinusENSMICP0000000929798.985897.3631
ENSG00000075618homo_sapiensENSP0000037179898.174496.5517octodon_degusENSODEP0000001701098.174496.5517
ENSG00000075618homo_sapiensENSP0000037179898.580196.9574jaculus_jaculusENSJJAP0000001814598.580196.9574
ENSG00000075618homo_sapiensENSP0000037179896.348993.3063ovis_aries_rambouilletENSOARP0002001094796.348993.3063
ENSG00000075618homo_sapiensENSP0000037179823.123722.1095ursus_maritimusENSUMAP0000001121298.275993.9655
ENSG00000075618homo_sapiensENSP0000037179880.324576.8763delphinapterus_leucasENSDLEP0000002920967.576864.6758
ENSG00000075618homo_sapiensENSP0000037179848.478741.9878physeter_catodonENSPCTP0000501227675.157265.0943
ENSG00000075618homo_sapiensENSP0000037179856.592355.3753physeter_catodonENSPCTP0000501985892.69190.6977
ENSG00000075618homo_sapiensENSP0000037179898.78396.5517mus_caroliMGP_CAROLIEiJ_P007194898.78396.5517
ENSG00000075618homo_sapiensENSP0000037179898.78396.5517mus_musculusENSMUSP0000003156598.78396.5517
ENSG00000075618homo_sapiensENSP0000037179898.377396.9574dipodomys_ordiiENSDORP0000001787598.377396.9574
ENSG00000075618homo_sapiensENSP0000037179899.391597.9716mustela_putorius_furoENSMPUP0000001650899.391597.9716
ENSG00000075618homo_sapiensENSP0000037179899.391598.9858aotus_nancymaaeENSANAP0000002692799.391598.9858
ENSG00000075618homo_sapiensENSP0000037179899.594399.3915saimiri_boliviensis_boliviensisENSSBOP0000001774099.594399.3915
ENSG00000075618homo_sapiensENSP0000037179899.797299.5943chlorocebus_sabaeusENSCSAP0000001369799.797299.5943
ENSG00000075618homo_sapiensENSP0000037179877.079176.0649tupaia_belangeriENSTBEP0000000614498.445697.1503
ENSG00000075618homo_sapiensENSP0000037179898.580196.3489mesocricetus_auratusENSMAUP0000002447298.580196.3489
ENSG00000075618homo_sapiensENSP0000037179896.957494.1176phocoena_sinusENSPSNP0000002255196.957494.1176
ENSG00000075618homo_sapiensENSP0000037179896.551793.712camelus_dromedariusENSCDRP0000502638896.356393.5223
ENSG00000075618homo_sapiensENSP0000037179846.653144.2191carlito_syrichtaENSTSYP0000002855182.142977.8571
ENSG00000075618homo_sapiensENSP0000037179842.393541.1765panthera_tigris_altaicaENSPTIP0000002629797.209394.4186
ENSG00000075618homo_sapiensENSP0000037179898.78395.9432rattus_norvegicusENSRNOP0000009340398.78395.9432
ENSG00000075618homo_sapiensENSP0000037179898.985897.1602prolemur_simusENSPSMP0000001524298.985897.1602
ENSG00000075618homo_sapiensENSP0000037179898.580196.3489microtus_ochrogasterENSMOCP0000000146598.580196.3489
ENSG00000075618homo_sapiensENSP0000037179898.985896.9574peromyscus_maniculatus_bairdiiENSPEMP0000002855898.985896.9574
ENSG00000075618homo_sapiensENSP0000037179893.306390.4665bos_mutusENSBMUP0000002829893.495990.6504
ENSG00000075618homo_sapiensENSP0000037179898.78396.5517mus_spicilegusENSMSIP0000003548298.78396.5517
ENSG00000075618homo_sapiensENSP0000037179898.78396.5517cricetulus_griseus_chok1gshdENSCGRP0000100901598.78396.5517
ENSG00000075618homo_sapiensENSP0000037179886.004184.3813pteropus_vampyrusENSPVAP0000001631985.140683.5341
ENSG00000075618homo_sapiensENSP0000037179894.726288.2353vombatus_ursinusENSVURP0001002383194.534488.0567
ENSG00000075618homo_sapiensENSP0000037179898.985897.3631rhinolophus_ferrumequinumENSRFEP0001001733785.464184.063
ENSG00000075618homo_sapiensENSP0000037179899.188697.5659neovison_visonENSNVIP0000000711699.188697.5659
ENSG00000075618homo_sapiensENSP0000037179896.14693.1034bos_taurusENSBTAP0000000414596.14693.1034
ENSG00000075618homo_sapiensENSP0000037179898.580196.5517heterocephalus_glaber_femaleENSHGLP0000001915381.818280.1347
ENSG00000075618homo_sapiensENSP0000037179899.797299.3915rhinopithecus_bietiENSRBIP0000000252499.797299.3915
ENSG00000075618homo_sapiensENSP0000037179899.594398.1744canis_lupus_dingoENSCAFP0002002172499.594398.1744
ENSG00000075618homo_sapiensENSP0000037179898.174496.3489sciurus_vulgarisENSSVLP0000503134998.174496.3489
ENSG00000075618homo_sapiensENSP0000037179894.726288.2353phascolarctos_cinereusENSPCIP0000001999194.534488.0567
ENSG00000075618homo_sapiensENSP0000037179874.239373.2252procavia_capensisENSPCAP0000001354397.86196.5241
ENSG00000075618homo_sapiensENSP0000037179897.768896.3489nannospalax_galiliENSNGAP0000000315397.768896.3489
ENSG00000075618homo_sapiensENSP0000037179896.14693.1034bos_grunniensENSBGRP0000002833496.14693.1034
ENSG00000075618homo_sapiensENSP0000037179899.188697.1602chinchilla_lanigeraENSCLAP0000002026399.188697.1602
ENSG00000075618homo_sapiensENSP0000037179893.306390.6694cervus_hanglu_yarkandensisENSCHYP0000003321587.286584.8197
ENSG00000075618homo_sapiensENSP0000037179896.754693.1034catagonus_wagneriENSCWAP0000002665396.754693.1034
ENSG00000075618homo_sapiensENSP0000037179898.78396.9574ictidomys_tridecemlineatusENSSTOP0000002184898.78396.9574
ENSG00000075618homo_sapiensENSP0000037179898.985897.7688otolemur_garnettiiENSOGAP0000001754096.442795.2569
ENSG00000075618homo_sapiensENSP0000037179899.391599.1886cebus_imitatorENSCCAP0000003448499.391599.1886
ENSG00000075618homo_sapiensENSP0000037179898.377396.7546urocitellus_parryiiENSUPAP0001001412798.377396.7546
ENSG00000075618homo_sapiensENSP0000037179888.032584.787moschus_moschiferusENSMMSP0000002385783.945880.8511
ENSG00000075618homo_sapiensENSP0000037179899.797299.5943rhinopithecus_roxellanaENSRROP0000001655599.797299.5943
ENSG00000075618homo_sapiensENSP0000037179898.78396.5517mus_pahariMGP_PahariEiJ_P006016198.78396.5517
ENSG00000075618homo_sapiensENSP0000037179899.188697.3631propithecus_coquereliENSPCOP0000000735399.188697.3631
ENSG00000075618homo_sapiensENSP0000037179861.054840.568drosophila_melanogasterFBpp007105858.789139.0625
ENSG00000075618homo_sapiensENSP0000037179863.894546.856ciona_intestinalisENSCINP0000000577464.417247.2393
ENSG00000075618homo_sapiensENSP0000037179852.129838.3367eptatretus_burgeriENSEBUP0000000181863.613946.7822
ENSG00000075618homo_sapiensENSP0000037179888.64178.7018callorhinchus_miliiENSCMIP0000004266689.183779.1837
ENSG00000075618homo_sapiensENSP0000037179891.480779.5132latimeria_chalumnaeENSLACP0000001868192.040880
ENSG00000075618homo_sapiensENSP0000037179889.046776.8763lepisosteus_oculatusENSLOCP0000000562487.276375.3479
ENSG00000075618homo_sapiensENSP0000037179846.247537.3225clupea_harengusENSCHAP0000001269782.014466.187
ENSG00000075618homo_sapiensENSP0000037179884.78766.5314danio_rerioENSDARP0000009442284.615466.3968
ENSG00000075618homo_sapiensENSP0000037179888.438175.4564danio_rerioENSDARP0000007764788.798475.7637
ENSG00000075618homo_sapiensENSP0000037179883.975767.14carassius_auratusENSCARP0000005172483.805767.0041
ENSG00000075618homo_sapiensENSP0000037179888.64175.8621carassius_auratusENSCARP0000010496989.00276.1711
ENSG00000075618homo_sapiensENSP0000037179888.64175.4564carassius_auratusENSCARP0000002025989.00275.7637
ENSG00000075618homo_sapiensENSP0000037179884.381366.1258carassius_auratusENSCARP0000006302684.210565.9919
ENSG00000075618homo_sapiensENSP0000037179879.310363.286astyanax_mexicanusENSAMXP0000000435879.959163.8037
ENSG00000075618homo_sapiensENSP0000037179889.046774.8479astyanax_mexicanusENSAMXP0000004634088.686974.5455
ENSG00000075618homo_sapiensENSP0000037179878.904764.503ictalurus_punctatusENSIPUP0000000215879.387864.898
ENSG00000075618homo_sapiensENSP0000037179888.843875.6592ictalurus_punctatusENSIPUP0000002585989.205775.9674
ENSG00000075618homo_sapiensENSP0000037179883.164370.5882esox_luciusENSELUP0000004734881.510969.1849
ENSG00000075618homo_sapiensENSP0000037179888.235374.645esox_luciusENSELUP0000003317887.349473.8956
ENSG00000075618homo_sapiensENSP0000037179884.584266.9371electrophorus_electricusENSEEEP0000003673684.41366.8016
ENSG00000075618homo_sapiensENSP0000037179888.235375.0507electrophorus_electricusENSEEEP0000000000688.594775.3564
ENSG00000075618homo_sapiensENSP0000037179884.178570.3854oncorhynchus_kisutchENSOKIP0000506131382.015868.5771
ENSG00000075618homo_sapiensENSP0000037179886.206972.8195oncorhynchus_kisutchENSOKIP0000509491685.341472.0884
ENSG00000075618homo_sapiensENSP0000037179884.178570.3854oncorhynchus_kisutchENSOKIP0000506931182.015868.5771
ENSG00000075618homo_sapiensENSP0000037179886.206972.8195oncorhynchus_kisutchENSOKIP0000510076485.341472.0884
ENSG00000075618homo_sapiensENSP0000037179886.612672.6166oncorhynchus_mykissENSOMYP0000010835685.74371.8876
ENSG00000075618homo_sapiensENSP0000037179883.975770.1826oncorhynchus_mykissENSOMYP0000005636681.818268.3794
ENSG00000075618homo_sapiensENSP0000037179886.409772.6166oncorhynchus_mykissENSOMYP0000012461885.542271.8876
ENSG00000075618homo_sapiensENSP0000037179883.975770.1826oncorhynchus_mykissENSOMYP0000013626781.818268.3794
ENSG00000075618homo_sapiensENSP0000037179883.975770.3854salmo_salarENSSSAP0000006424380.701867.6413
ENSG00000075618homo_sapiensENSP0000037179876.876364.3002salmo_salarENSSSAP0000006412168.659457.4275
ENSG00000075618homo_sapiensENSP0000037179856.186645.6389salmo_salarENSSSAP0000012464183.685867.9758
ENSG00000075618homo_sapiensENSP0000037179886.206972.211salmo_salarENSSSAP0000016490085.170371.3427
ENSG00000075618homo_sapiensENSP0000037179885.395571.6024salmo_salarENSSSAP0000012539880.961567.8846
ENSG00000075618homo_sapiensENSP0000037179885.801272.211salmo_truttaENSSTUP0000011136584.769571.3427
ENSG00000075618homo_sapiensENSP0000037179881.541667.3428gadus_morhuaENSGMOP0000001929380.885366.8008
ENSG00000075618homo_sapiensENSP0000037179882.961568.1542fundulus_heteroclitusENSFHEP0000000378683.299468.4318
ENSG00000075618homo_sapiensENSP0000037179887.423974.2393fundulus_heteroclitusENSFHEP0000000953086.546273.494
ENSG00000075618homo_sapiensENSP0000037179883.367167.9513poecilia_reticulataENSPREP0000000005783.706768.2281
ENSG00000075618homo_sapiensENSP0000037179886.206973.2252poecilia_reticulataENSPREP0000002713987.448674.2798
ENSG00000075618homo_sapiensENSP0000037179882.961567.3428xiphophorus_maculatusENSXMAP0000001287483.299467.6171
ENSG00000075618homo_sapiensENSP0000037179887.423974.0365xiphophorus_maculatusENSXMAP0000000099186.546273.2932
ENSG00000075618homo_sapiensENSP0000037179881.947367.9513oryzias_latipesENSORLP0000001206282.113868.0894
ENSG00000075618homo_sapiensENSP0000037179888.032574.8479oryzias_latipesENSORLP0000001713887.148674.0964
ENSG00000075618homo_sapiensENSP0000037179887.221173.8337cyclopterus_lumpusENSCLMP0000502070386.345473.0924
ENSG00000075618homo_sapiensENSP0000037179883.164368.1542cyclopterus_lumpusENSCLMP0000500041682.49567.6056
ENSG00000075618homo_sapiensENSP0000037179887.829674.645oreochromis_niloticusENSONIP0000007347373.514462.4788
ENSG00000075618homo_sapiensENSP0000037179882.150165.9229oreochromis_niloticusENSONIP0000000023082.317166.0569
ENSG00000075618homo_sapiensENSP0000037179882.150166.5314haplochromis_burtoniENSHBUP0000003036882.317166.6667
ENSG00000075618homo_sapiensENSP0000037179887.626874.645haplochromis_burtoniENSHBUP0000001212473.720162.7986
ENSG00000075618homo_sapiensENSP0000037179882.150166.5314astatotilapia_callipteraENSACLP0000000636582.317166.6667
ENSG00000075618homo_sapiensENSP0000037179887.626874.645astatotilapia_callipteraENSACLP0000001573486.74773.8956
ENSG00000075618homo_sapiensENSP0000037179883.367168.1542sparus_aurataENSSAUP0001000453283.030367.8788
ENSG00000075618homo_sapiensENSP0000037179887.626873.6308sparus_aurataENSSAUP0001003661986.921573.0382
ENSG00000075618homo_sapiensENSP0000037179887.423974.4422lates_calcariferENSLCAP0001002224286.546273.6948
ENSG00000075618homo_sapiensENSP0000037179883.367168.5598lates_calcariferENSLCAP0001004927066.829354.9594
ENSG00000075618homo_sapiensENSP0000037179883.772871.3996xenopus_tropicalisENSXETP0000001634585.507272.8778
ENSG00000075618homo_sapiensENSP0000037179892.292183.57chrysemys_picta_belliiENSCPBP0000002952892.857184.0816
ENSG00000075618homo_sapiensENSP0000037179893.306383.3671sphenodon_punctatusENSSPUP0000000375993.877583.8775
ENSG00000075618homo_sapiensENSP0000037179889.452378.7018crocodylus_porosusENSCPRP0000502334089.816779.0224
ENSG00000075618homo_sapiensENSP0000037179849.087242.5963laticauda_laticaudataENSLLTP0000001960786.428675
ENSG00000075618homo_sapiensENSP0000037179837.728231.643laticauda_laticaudataENSLLTP0000001319293.939478.7879
ENSG00000075618homo_sapiensENSP0000037179889.655276.8763notechis_scutatusENSNSUP0000001941489.292976.5657
ENSG00000075618homo_sapiensENSP0000037179837.525431.643pseudonaja_textilisENSPTXP0000000926893.434378.7879
ENSG00000075618homo_sapiensENSP0000037179858.823548.2759pseudonaja_textilisENSPTXP0000000926961.833750.7463
ENSG00000075618homo_sapiensENSP0000037179849.087244.4219anas_platyrhynchos_platyrhynchosENSAPLP000000293418879.6364
ENSG00000075618homo_sapiensENSP0000037179891.277981.3387gallus_gallusENSGALP0001003066491.836781.8367
ENSG00000075618homo_sapiensENSP0000037179835.49728.1947meleagris_gallopavoENSMGAP0000003154051.775141.1243
ENSG00000075618homo_sapiensENSP0000037179842.596337.5254meleagris_gallopavoENSMGAP0000000365791.304380.4348
ENSG00000075618homo_sapiensENSP0000037179847.464539.7566serinus_canariaENSSCAP0000001211876.221563.8436
ENSG00000075618homo_sapiensENSP0000037179890.669480.3245parus_majorENSPMJP0000002356991.224580.8163
ENSG00000075618homo_sapiensENSP0000037179841.379336.5112anolis_carolinensisENSACAP0000002969094.883783.7209
ENSG00000075618homo_sapiensENSP0000037179887.626874.645neolamprologus_brichardiENSNBRP0000000596686.74773.8956
ENSG00000075618homo_sapiensENSP0000037179881.541665.9229neolamprologus_brichardiENSNBRP0000000813982.208666.4622
ENSG00000075618homo_sapiensENSP0000037179851.724144.2191naja_najaENSNNAP0000002488581.469769.6486
ENSG00000075618homo_sapiensENSP0000037179837.728231.643naja_najaENSNNAP0000002487393.939478.7879
ENSG00000075618homo_sapiensENSP0000037179893.103481.3387podarcis_muralisENSPMRP0000002299293.482781.6701
ENSG00000075618homo_sapiensENSP0000037179848.681540.1623geospiza_fortisENSGFOP0000001362778.431464.7059
ENSG00000075618homo_sapiensENSP0000037179879.71670.7911taeniopygia_guttataENSTGUP0000000788888.314678.427
ENSG00000075618homo_sapiensENSP0000037179890.669477.0791erpetoichthys_calabaricusENSECRP0000002957091.224577.551
ENSG00000075618homo_sapiensENSP0000037179882.352966.9371erpetoichthys_calabaricusENSECRP0000002069082.857167.3469
ENSG00000075618homo_sapiensENSP0000037179887.018374.645kryptolebias_marmoratusENSKMAP0000002155986.144673.8956
ENSG00000075618homo_sapiensENSP0000037179883.164368.357kryptolebias_marmoratusENSKMAP0000001231683.673568.7755
ENSG00000075618homo_sapiensENSP0000037179891.683681.3387salvator_merianaeENSSMRP0000002621192.244981.8367
ENSG00000075618homo_sapiensENSP0000037179882.150169.3712oryzias_javanicusENSOJAP0000002693284.905771.6981
ENSG00000075618homo_sapiensENSP0000037179881.947367.7485oryzias_javanicusENSOJAP0000002322782.113867.8862
ENSG00000075618homo_sapiensENSP0000037179887.829674.4422amphilophus_citrinellusENSACIP0000001148586.947873.6948
ENSG00000075618homo_sapiensENSP0000037179883.164367.7485amphilophus_citrinellusENSACIP0000003065183.333367.8862
ENSG00000075618homo_sapiensENSP0000037179887.829674.4422dicentrarchus_labraxENSDLAP0000501416386.947873.6948
ENSG00000075618homo_sapiensENSP0000037179883.367168.357dicentrarchus_labraxENSDLAP0000504949783.030368.0808
ENSG00000075618homo_sapiensENSP0000037179887.829674.4422amphiprion_perculaENSAPEP0000001569186.947873.6948
ENSG00000075618homo_sapiensENSP0000037179884.178568.5598amphiprion_perculaENSAPEP0000001562571.428658.1756
ENSG00000075618homo_sapiensENSP0000037179881.947368.1542oryzias_sinensisENSOSIP0000003244382.113868.2927
ENSG00000075618homo_sapiensENSP0000037179887.829674.645oryzias_sinensisENSOSIP0000001693286.947873.8956
ENSG00000075618homo_sapiensENSP0000037179891.886484.3813pelodiscus_sinensisENSPSIP0000001210892.44984.898
ENSG00000075618homo_sapiensENSP0000037179892.089283.57gopherus_evgoodeiENSGEVP0000501130092.653184.0816
ENSG00000075618homo_sapiensENSP0000037179892.089283.7728chelonoidis_abingdoniiENSCABP0000000779292.653184.2857
ENSG00000075618homo_sapiensENSP0000037179888.032574.0365seriola_dumeriliENSSDUP0000002578687.148673.2932
ENSG00000075618homo_sapiensENSP0000037179883.5768.357seriola_dumeriliENSSDUP0000002060583.232368.0808
ENSG00000075618homo_sapiensENSP0000037179883.367167.7485cottoperca_gobioENSCGOP0000001076882.862967.3387
ENSG00000075618homo_sapiensENSP0000037179887.018374.0365cottoperca_gobioENSCGOP0000000780786.144673.2932
ENSG00000075618homo_sapiensENSP0000037179846.450339.7566anser_brachyrhynchusENSABRP0000000198685.447873.1343
ENSG00000075618homo_sapiensENSP0000037179851.115645.8418anser_brachyrhynchusENSABRP0000002582185.423776.6102
ENSG00000075618homo_sapiensENSP0000037179880.730266.5314gasterosteus_aculeatusENSGACP0000002181982.061967.6289
ENSG00000075618homo_sapiensENSP0000037179886.409773.8337gasterosteus_aculeatusENSGACP0000001046986.409773.8337
ENSG00000075618homo_sapiensENSP0000037179887.423973.428cynoglossus_semilaevisENSCSEP0000002988986.546272.6908
ENSG00000075618homo_sapiensENSP0000037179881.135967.3428cynoglossus_semilaevisENSCSEP0000000325081.300867.4797
ENSG00000075618homo_sapiensENSP0000037179883.5768.1542poecilia_formosaENSPFOP0000001152183.910468.4318
ENSG00000075618homo_sapiensENSP0000037179887.626874.2393poecilia_formosaENSPFOP0000001519686.74773.494
ENSG00000075618homo_sapiensENSP0000037179883.772870.1826myripristis_murdjanENSMMDP0000500150883.603270.0405
ENSG00000075618homo_sapiensENSP0000037179888.235374.2393myripristis_murdjanENSMMDP0000501270987.349473.494
ENSG00000075618homo_sapiensENSP0000037179883.5767.9513sander_luciopercaENSSLUP0000000223080.311965.3021
ENSG00000075618homo_sapiensENSP0000037179887.626874.4422sander_luciopercaENSSLUP0000001012986.74773.6948
ENSG00000075618homo_sapiensENSP0000037179890.466580.5274strigops_habroptilaENSSHBP0000501092791.020481.0204
ENSG00000075618homo_sapiensENSP0000037179884.178568.7627amphiprion_ocellarisENSAOCP0000003133671.305858.2474
ENSG00000075618homo_sapiensENSP0000037179887.829674.4422amphiprion_ocellarisENSAOCP0000000232086.947873.6948
ENSG00000075618homo_sapiensENSP0000037179892.292183.3671terrapene_carolina_triunguisENSTMTP0000001901392.857183.8775
ENSG00000075618homo_sapiensENSP0000037179878.904767.3428hucho_huchoENSHHUP0000002098983.297671.0921
ENSG00000075618homo_sapiensENSP0000037179881.338767.3428betta_splendensENSBSLP0000000461981.670167.6171
ENSG00000075618homo_sapiensENSP0000037179887.626874.2393betta_splendensENSBSLP0000000310886.74773.494
ENSG00000075618homo_sapiensENSP0000037179879.310363.6917pygocentrus_nattereriENSPNAP0000000922579.471563.8211
ENSG00000075618homo_sapiensENSP0000037179888.64174.645pygocentrus_nattereriENSPNAP0000001648188.64174.645
ENSG00000075618homo_sapiensENSP0000037179888.032574.645anabas_testudineusENSATEP0000000979487.148673.8956
ENSG00000075618homo_sapiensENSP0000037179883.5768.9655anabas_testudineusENSATEP0000000761783.232368.6869
ENSG00000075618homo_sapiensENSP0000037179863.894547.4645ciona_savignyiENSCSAVP0000001854464.154847.6578
ENSG00000075618homo_sapiensENSP0000037179883.367168.1542seriola_lalandi_dorsalisENSSLDP0000002083268.159255.7214
ENSG00000075618homo_sapiensENSP0000037179888.032574.0365seriola_lalandi_dorsalisENSSLDP0000002504687.148673.2932
ENSG00000075618homo_sapiensENSP0000037179887.829674.4422labrus_bergyltaENSLBEP0000001277586.947873.6948
ENSG00000075618homo_sapiensENSP0000037179882.961567.7485labrus_bergyltaENSLBEP0000001144082.961567.7485
ENSG00000075618homo_sapiensENSP0000037179882.150166.3286pundamilia_nyerereiENSPNYP0000000868982.317166.4634
ENSG00000075618homo_sapiensENSP0000037179887.626874.645pundamilia_nyerereiENSPNYP0000002436286.74773.8956
ENSG00000075618homo_sapiensENSP0000037179888.235375.2535mastacembelus_armatusENSMAMP0000000901787.349474.498
ENSG00000075618homo_sapiensENSP0000037179884.178568.1542mastacembelus_armatusENSMAMP0000001062283.838467.8788
ENSG00000075618homo_sapiensENSP0000037179887.829674.4422stegastes_partitusENSSPAP0000002058686.947873.6948
ENSG00000075618homo_sapiensENSP0000037179882.961568.357stegastes_partitusENSSPAP0000000305381.150866.8651
ENSG00000075618homo_sapiensENSP0000037179833.671426.7748oncorhynchus_tshawytschaENSOTSP0000504778667.479753.6585
ENSG00000075618homo_sapiensENSP0000037179883.772868.1542acanthochromis_polyacanthusENSAPOP0000003190983.434367.8788
ENSG00000075618homo_sapiensENSP0000037179887.626874.4422acanthochromis_polyacanthusENSAPOP0000002313286.74773.6948
ENSG00000075618homo_sapiensENSP0000037179890.466580.7302aquila_chrysaetos_chrysaetosENSACCP0002001889891.020481.2245
ENSG00000075618homo_sapiensENSP0000037179881.338766.9371nothobranchius_furzeriENSNFUP0001500110581.670167.2098
ENSG00000075618homo_sapiensENSP0000037179887.626874.8479nothobranchius_furzeriENSNFUP0001500636986.74774.0964
ENSG00000075618homo_sapiensENSP0000037179888.032574.645cyprinodon_variegatusENSCVAP0000002156587.148673.8956
ENSG00000075618homo_sapiensENSP0000037179882.758668.357cyprinodon_variegatusENSCVAP0000001585283.095768.6354
ENSG00000075618homo_sapiensENSP0000037179834.482825.5578denticeps_clupeoidesENSDCDP0000002771869.387851.4286
ENSG00000075618homo_sapiensENSP0000037179888.438175.4564denticeps_clupeoidesENSDCDP0000001253988.798475.7637
ENSG00000075618homo_sapiensENSP0000037179872.819555.5781denticeps_clupeoidesENSDCDP0000000288266.358650.6469
ENSG00000075618homo_sapiensENSP0000037179882.961568.357larimichthys_croceaENSLCRP0000500608482.961568.357
ENSG00000075618homo_sapiensENSP0000037179888.032574.2393larimichthys_croceaENSLCRP0000502406481.886869.0566
ENSG00000075618homo_sapiensENSP0000037179883.164367.5456takifugu_rubripesENSTRUP0000003802782.828367.2727
ENSG00000075618homo_sapiensENSP0000037179888.235374.2393takifugu_rubripesENSTRUP0000001253487.349473.494
ENSG00000075618homo_sapiensENSP0000037179890.466580.1217ficedula_albicollisENSFALP0000001442791.020480.6122
ENSG00000075618homo_sapiensENSP0000037179886.206973.0223hippocampus_comesENSHCOP0000002082085.341472.2892
ENSG00000075618homo_sapiensENSP0000037179886.612674.4422cyprinus_carpio_carpioENSCCRP0000012644185.74373.6948
ENSG00000075618homo_sapiensENSP0000037179884.178566.7343cyprinus_carpio_carpioENSCCRP0000004164884.008166.5992
ENSG00000075618homo_sapiensENSP0000037179884.178567.5456cyprinus_carpio_carpioENSCCRP0000004810284.008167.4089
ENSG00000075618homo_sapiensENSP0000037179888.032576.2677cyprinus_carpio_carpioENSCCRP0000000278988.39176.5784
ENSG00000075618homo_sapiensENSP0000037179891.277981.7444coturnix_japonicaENSCJPP0000500031391.836782.2449
ENSG00000075618homo_sapiensENSP0000037179887.626874.2393poecilia_latipinnaENSPLAP0000002278286.74773.494
ENSG00000075618homo_sapiensENSP0000037179883.5767.9513poecilia_latipinnaENSPLAP0000000445483.910468.2281
ENSG00000075618homo_sapiensENSP0000037179883.772867.5456sinocyclocheilus_grahamiENSSGRP0000002543283.603267.4089
ENSG00000075618homo_sapiensENSP0000037179835.49729.8174sinocyclocheilus_grahamiENSSGRP0000000620188.832574.6193
ENSG00000075618homo_sapiensENSP0000037179888.032576.4706sinocyclocheilus_grahamiENSSGRP0000004488388.39176.7821
ENSG00000075618homo_sapiensENSP0000037179845.436137.5254sinocyclocheilus_grahamiENSSGRP0000000095079.715365.8363
ENSG00000075618homo_sapiensENSP0000037179884.584267.3428sinocyclocheilus_grahamiENSSGRP0000003734384.41367.2065
ENSG00000075618homo_sapiensENSP0000037179887.626874.645maylandia_zebraENSMZEP0000500972373.720162.7986
ENSG00000075618homo_sapiensENSP0000037179882.150166.5314maylandia_zebraENSMZEP0000501794782.317166.6667
ENSG00000075618homo_sapiensENSP0000037179880.324565.7201tetraodon_nigroviridisENSTNIP0000001108982.328567.3597
ENSG00000075618homo_sapiensENSP0000037179886.815475.0507tetraodon_nigroviridisENSTNIP0000000701385.429173.8523
ENSG00000075618homo_sapiensENSP0000037179883.164370.7911tetraodon_nigroviridisENSTNIP0000001726083.333370.935
ENSG00000075618homo_sapiensENSP0000037179884.178569.9797paramormyrops_kingsleyaeENSPKIP0000002909384.521470.2648
ENSG00000075618homo_sapiensENSP0000037179888.235374.8479paramormyrops_kingsleyaeENSPKIP0000004156589.87676.2397
ENSG00000075618homo_sapiensENSP0000037179886.815472.211scleropages_formosusENSSFOP0001505487586.991972.3577
ENSG00000075618homo_sapiensENSP0000037179889.452376.4706scleropages_formosusENSSFOP0001501021489.816776.7821
ENSG00000075618homo_sapiensENSP0000037179880.527466.7343leptobrachium_leishanenseENSLLEP0000003003584.648270.1493
ENSG00000075618homo_sapiensENSP0000037179881.744468.357scophthalmus_maximusENSSMAP0000004204163.364852.9874
ENSG00000075618homo_sapiensENSP0000037179882.555868.1542scophthalmus_maximusENSSMAP0000004363582.388768.0162
ENSG00000075618homo_sapiensENSP0000037179888.235374.8479oryzias_melastigmaENSOMEP0000002443787.349474.0964
ENSG00000075618homo_sapiensENSP0000037179881.947367.5456oryzias_melastigmaENSOMEP0000001821782.113867.6829

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001725located_in stress fiber1IDAHomo_sapiens(9606)Component
GO:0001726is_active_in ruffle2IBA,IDAHomo_sapiens(9606)Component
GO:0002102located_in podosome1IDAHomo_sapiens(9606)Component
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003779enables actin binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005856located_in cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0005902is_active_in microvillus2IBA,IDAHomo_sapiens(9606)Component
GO:0005911located_in cell-cell junction1IDAHomo_sapiens(9606)Component
GO:0005938located_in cell cortex1IEAHomo_sapiens(9606)Component
GO:0007043involved_in cell-cell junction assembly1IDAHomo_sapiens(9606)Process
GO:0007163involved_in establishment or maintenance of cell polarity1IBAHomo_sapiens(9606)Process
GO:0010592involved_in positive regulation of lamellipodium assembly1IDAHomo_sapiens(9606)Process
GO:0015629is_active_in actin cytoskeleton2IBA,IDAHomo_sapiens(9606)Component
GO:0016477involved_in cell migration2IBA,IMPHomo_sapiens(9606)Process
GO:0030027is_active_in lamellipodium2IBA,ISSHomo_sapiens(9606)Component
GO:0030035involved_in microspike assembly2IDA,IMPHomo_sapiens(9606)Process
GO:0030036involved_in actin cytoskeleton organization1IDAHomo_sapiens(9606)Process
GO:0030046involved_in parallel actin filament bundle assembly1IDAHomo_sapiens(9606)Process
GO:0030175is_active_in filopodium2IBA,IDAHomo_sapiens(9606)Component
GO:0030426is_active_in growth cone2IBA,ISSHomo_sapiens(9606)Component
GO:0030674enables protein-macromolecule adaptor activity1IEAHomo_sapiens(9606)Function
GO:0031253is_active_in cell projection membrane2IBA,IDAHomo_sapiens(9606)Component
GO:0032534involved_in regulation of microvillus assembly1IDAHomo_sapiens(9606)Process
GO:0032956involved_in regulation of actin cytoskeleton organization1IDAHomo_sapiens(9606)Process
GO:0035089involved_in establishment of apical/basal cell polarity1IDAHomo_sapiens(9606)Process
GO:0044393located_in microspike1IDAHomo_sapiens(9606)Component
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0048870involved_in cell motility1IDAHomo_sapiens(9606)Process
GO:0051015enables actin filament binding2IBA,IDAHomo_sapiens(9606)Function
GO:0051017involved_in actin filament bundle assembly2IBA,IDAHomo_sapiens(9606)Process
GO:0051491involved_in positive regulation of filopodium assembly2IDA,IMPHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0071803involved_in positive regulation of podosome assembly1IDAHomo_sapiens(9606)Process
GO:0090091involved_in positive regulation of extracellular matrix disassembly1IDAHomo_sapiens(9606)Process

Expression