Functions and Diseases

RBP Type Canonical_RBPs
Diseases SARS-COV-2
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000067596 Gene ID 1659 Accession 2749
Symbol DHX8 Alias DDX8;Dhr2;HRH1;PRP22;PRPF22 Full Name DEAH-box helicase 8
Status Confidence Length 106877 bases Strand Plus strand
Position 17 : 43483865 - 43590741 RNA binding domain HA2 , S1 , OB_NTP_bind
Summary This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression