Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq DataSet_01_158 DataSet_01_210

Description

Ensembl ID ENSG00000067225 Gene ID 5315 Accession 9021
Symbol PKM Alias PK3;TCB;p58;OIP3;PKM2;CTHBP;THBP1;HEL-S-30 Full Name pyruvate kinase M1/2
Status Confidence Length 32791 bases Strand Minus strand
Position 15 : 72199029 - 72231819 RNA binding domain N.A.
Summary This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
20010808 HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. J Charles David 2010-01-21 Nature
37224531 Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling. S Nevraj Kejiou 2023-07-07 Nucleic acids research
35973722 The mutual interaction of glycolytic enzymes and RNA in post-transcriptional regulation. Melanie Wegener 2022-11-01 RNA (New York, N.Y.)
22307054 Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins. Mo Chen 2012-02-05 Nature structural & molecular biology
29106606 Increased Affinity for RNA Targets Evolved Early in Animal and Plant Dicer Lineages through Different Structural Mechanisms. Haiyan Jia 2017-12-01 Molecular biology and evolution

Transcripts

Name Transcript ID bp Protein Translation ID
PKM-211 ENST00000564440 3016 No protein -
PKM-202 ENST00000335181 2305 531aa ENSP00000334983
PKM-224 ENST00000698740 2448 344aa ENSP00000513902
PKM-201 ENST00000319622 2717 531aa ENSP00000320171
PKM-203 ENST00000389093 2279 457aa ENSP00000373745
PKM-225 ENST00000698741 2578 605aa ENSP00000513903
PKM-215 ENST00000565184 2503 566aa ENSP00000455736
PKM-213 ENST00000565143 2301 No protein -
PKM-218 ENST00000567118 2254 69aa ENSP00000456004
PKM-214 ENST00000565154 2004 605aa ENSP00000455901
PKM-219 ENST00000568459 1806 531aa ENSP00000456970
PKM-204 ENST00000561609 1568 485aa ENSP00000457253
PKM-208 ENST00000563986 825 No protein -
PKM-222 ENST00000569857 1355 281aa ENSP00000455584
PKM-223 ENST00000570166 626 No protein -
PKM-212 ENST00000564993 663 No protein -
PKM-207 ENST00000563275 699 No protein -
PKM-220 ENST00000568743 580 No protein -
PKM-205 ENST00000562784 529 No protein -
PKM-209 ENST00000564178 554 168aa ENSP00000457198
PKM-206 ENST00000562997 582 162aa ENSP00000457830
PKM-217 ENST00000567087 550 151aa ENSP00000456984
PKM-210 ENST00000564276 753 No protein -
PKM-216 ENST00000566809 560 82aa ENSP00000457420
PKM-221 ENST00000569050 457 51aa ENSP00000454668

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
96163S-(3-hydroxypropyl)cysteine N-acetate9E-626053186
96164Smoking9E-626053186

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000067225homo_sapiensENSP0000033993378.048865.5052homo_sapiensENSP0000033498384.369170.8098

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000067225homo_sapiensENSP0000033498387.758984.9341nomascus_leucogenysENSNLEP0000003320576.143873.6928
ENSG00000067225homo_sapiensENSP0000033498397.740196.9868nomascus_leucogenysENSNLEP0000004149497.924597.1698
ENSG00000067225homo_sapiensENSP00000334983100100pan_paniscusENSPPAP0000003669395.503695.5036
ENSG00000067225homo_sapiensENSP00000334983100100pan_troglodytesENSPTRP0000008983595.503695.5036
ENSG00000067225homo_sapiensENSP00000334983100100gorilla_gorillaENSGGOP0000004881195.503695.5036
ENSG00000067225homo_sapiensENSP0000033498396.421892.8437ornithorhynchus_anatinusENSOANP0000000821996.421892.8437
ENSG00000067225homo_sapiensENSP0000033498390.960485.4991sarcophilus_harrisiiENSSHAP0000003383281.864476.9492
ENSG00000067225homo_sapiensENSP0000033498389.265581.3559sarcophilus_harrisiiENSSHAP0000000073489.265581.3559
ENSG00000067225homo_sapiensENSP0000033498385.122480.0377notamacropus_eugeniiENSMEUP0000000410087.427582.205
ENSG00000067225homo_sapiensENSP0000033498391.337188.1356choloepus_hoffmanniENSCHOP0000001195896.421593.0417
ENSG00000067225homo_sapiensENSP0000033498397.363594.3503dasypus_novemcinctusENSDNOP0000000650497.363594.3503
ENSG00000067225homo_sapiensENSP0000033498394.915391.7137echinops_telfairiENSETEP0000000723295.454592.2348
ENSG00000067225homo_sapiensENSP0000033498391.148889.2655callithrix_jacchusENSCJAP0000005572295.463593.4911
ENSG00000067225homo_sapiensENSP0000033498399.246798.8701callithrix_jacchusENSCJAP0000003436399.246798.8701
ENSG00000067225homo_sapiensENSP0000033498396.045294.9153callithrix_jacchusENSCJAP0000001918390.10689.0459
ENSG00000067225homo_sapiensENSP0000033498399.43599.2467cercocebus_atysENSCATP0000002919094.96494.7842
ENSG00000067225homo_sapiensENSP0000033498387.758986.8173cercocebus_atysENSCATP0000000211799.360398.2942
ENSG00000067225homo_sapiensENSP0000033498393.408791.7137cercocebus_atysENSCATP0000000315197.254995.4902
ENSG00000067225homo_sapiensENSP0000033498355.555655.1789macaca_fascicularisENSMFAP0000004350096.721396.0656
ENSG00000067225homo_sapiensENSP0000033498361.205361.0169macaca_fascicularisENSMFAP0000004346199.085498.7805
ENSG00000067225homo_sapiensENSP0000033498359.510459.1337macaca_fascicularisENSMFAP0000004260496.932596.319
ENSG00000067225homo_sapiensENSP0000033498310099.8117macaca_fascicularisENSMFAP0000002627389.695989.527
ENSG00000067225homo_sapiensENSP0000033498374.011373.258macaca_mulattaENSMMUP0000005403198.743797.7387
ENSG00000067225homo_sapiensENSP0000033498391.525490.9604macaca_mulattaENSMMUP0000005365497.00696.4072
ENSG00000067225homo_sapiensENSP0000033498395.103694.3503macaca_nemestrinaENSMNEP0000004577596.558395.7935
ENSG00000067225homo_sapiensENSP0000033498398.116895.6685papio_anubisENSPANP0000001423198.116895.6685
ENSG00000067225homo_sapiensENSP0000033498354.04952.919mandrillus_leucophaeusENSMLEP0000000715197.952295.9044
ENSG00000067225homo_sapiensENSP0000033498310099.8117mandrillus_leucophaeusENSMLEP0000003570595.503695.3237
ENSG00000067225homo_sapiensENSP0000033498396.986893.9736tursiops_truncatusENSTTRP0000000897996.986893.9736
ENSG00000067225homo_sapiensENSP0000033498399.058498.4934vulpes_vulpesENSVVUP0000002487189.001788.4941
ENSG00000067225homo_sapiensENSP0000033498398.870197.7401equus_asinusENSEASP0000500739187.939786.9347
ENSG00000067225homo_sapiensENSP0000033498396.986893.597capra_hircusENSCHIP0000001541796.986893.597
ENSG00000067225homo_sapiensENSP0000033498396.986894.162loxodonta_africanaENSLAFP0000001502096.804593.985
ENSG00000067225homo_sapiensENSP0000033498398.493497.5518panthera_leoENSPLOP0000000549898.493497.5518
ENSG00000067225homo_sapiensENSP0000033498342.749542.7495ailuropoda_melanoleucaENSAMEP00000028311100100
ENSG00000067225homo_sapiensENSP0000033498397.363594.3503ailuropoda_melanoleucaENSAMEP0000000647444.917543.5274
ENSG00000067225homo_sapiensENSP0000033498398.681797.5518bos_indicus_hybridENSBIXP000050462588079.084
ENSG00000067225homo_sapiensENSP0000033498332.5827.1186oryctolagus_cuniculusENSOCUP0000003305665.28354.3396
ENSG00000067225homo_sapiensENSP0000033498393.220388.1356oryctolagus_cuniculusENSOCUP0000000530193.572888.4688
ENSG00000067225homo_sapiensENSP0000033498396.986893.4087equus_caballusENSECAP0000005298786.264783.0821
ENSG00000067225homo_sapiensENSP0000033498397.363594.5386canis_lupus_familiarisENSCAFP0084503288097.363594.5386
ENSG00000067225homo_sapiensENSP0000033498346.892743.3145canis_lupus_familiarisENSCAFP0084500303880.582574.4337
ENSG00000067225homo_sapiensENSP0000033498398.493497.5518panthera_pardusENSPPRP0000002154698.493497.5518
ENSG00000067225homo_sapiensENSP0000033498399.058497.9284marmota_marmota_marmotaENSMMMP0000000466992.605691.5493
ENSG00000067225homo_sapiensENSP0000033498398.493497.3635balaenoptera_musculusENSBMSP0001000147598.493497.3635
ENSG00000067225homo_sapiensENSP0000033498398.116896.6102cavia_porcellusENSCPOP0000000810198.116896.6102
ENSG00000067225homo_sapiensENSP0000033498364.218563.2768felis_catusENSFCAP0000001694896.600695.1841
ENSG00000067225homo_sapiensENSP0000033498397.175194.3503ursus_americanusENSUAMP0000003378097.175194.3503
ENSG00000067225homo_sapiensENSP0000033498390.395584.9341monodelphis_domesticaENSMODP0000000231275.590671.0236
ENSG00000067225homo_sapiensENSP0000033498398.681797.5518bison_bison_bisonENSBBBP0000002519898.681797.5518
ENSG00000067225homo_sapiensENSP0000033498398.116896.9868monodon_monocerosENSMMNP0001501284198.116896.9868
ENSG00000067225homo_sapiensENSP0000033498379.284474.0113sus_scrofaENSSSCP0000003120464.079159.8174
ENSG00000067225homo_sapiensENSP0000033498398.305198.3051microcebus_murinusENSMICP0000001234594.054194.0541
ENSG00000067225homo_sapiensENSP0000033498389.453986.8173octodon_degusENSODEP0000001032894.433491.6501
ENSG00000067225homo_sapiensENSP0000033498375.517971.1864octodon_degusENSODEP0000001341289.111184
ENSG00000067225homo_sapiensENSP0000033498373.634768.1733octodon_degusENSODEP0000001141287.47280.9843
ENSG00000067225homo_sapiensENSP0000033498394.16291.5254octodon_degusENSODEP0000000215391.240988.6861
ENSG00000067225homo_sapiensENSP0000033498351.035849.3409octodon_degusENSODEP0000001404797.48294.2446
ENSG00000067225homo_sapiensENSP0000033498369.303265.5367jaculus_jaculusENSJJAP0000000261184.597780
ENSG00000067225homo_sapiensENSP0000033498398.681797.1751ovis_aries_rambouilletENSOARP0002000453698.681797.1751
ENSG00000067225homo_sapiensENSP0000033498397.175196.4218ursus_maritimusENSUMAP0000001182098.850698.0843
ENSG00000067225homo_sapiensENSP0000033498396.986893.7853ochotona_princepsENSOPRP0000000787396.986893.7853
ENSG00000067225homo_sapiensENSP0000033498398.116896.9868delphinapterus_leucasENSDLEP0000000279998.116896.9868
ENSG00000067225homo_sapiensENSP0000033498396.610293.597physeter_catodonENSPCTP0000501548596.610293.597
ENSG00000067225homo_sapiensENSP0000033498396.421893.7853mus_caroliMGP_CAROLIEiJ_P008815996.421893.7853
ENSG00000067225homo_sapiensENSP0000033498398.305197.7401mus_musculusENSMUSP0000003483498.305197.7401
ENSG00000067225homo_sapiensENSP0000033498396.421892.8437dipodomys_ordiiENSDORP0000000772096.421892.8437
ENSG00000067225homo_sapiensENSP0000033498398.870198.3051mustela_putorius_furoENSMPUP0000001701790.673690.1554
ENSG00000067225homo_sapiensENSP0000033498394.16291.3371aotus_nancymaaeENSANAP0000000297694.876792.0304
ENSG00000067225homo_sapiensENSP0000033498392.278787.7589aotus_nancymaaeENSANAP0000002222991.247786.7784
ENSG00000067225homo_sapiensENSP0000033498399.623499.435saimiri_boliviensis_boliviensisENSSBOP0000002304098.327198.1413
ENSG00000067225homo_sapiensENSP0000033498399.058497.9284chlorocebus_sabaeusENSCSAP0000001817099.058497.9284
ENSG00000067225homo_sapiensENSP0000033498398.305197.3635mesocricetus_auratusENSMAUP0000002451798.490697.5472
ENSG00000067225homo_sapiensENSP0000033498375.706271.5631mesocricetus_auratusENSMAUP0000000133189.135384.2572
ENSG00000067225homo_sapiensENSP0000033498385.122482.4859mesocricetus_auratusENSMAUP0000002365492.622989.7541
ENSG00000067225homo_sapiensENSP0000033498398.305197.1751phocoena_sinusENSPSNP0000000030498.305197.1751
ENSG00000067225homo_sapiensENSP0000033498396.986893.597camelus_dromedariusENSCDRP0000501597447.204445.5545
ENSG00000067225homo_sapiensENSP0000033498399.246798.1168carlito_syrichtaENSTSYP0000001442898.137897.0205
ENSG00000067225homo_sapiensENSP0000033498398.493497.5518panthera_tigris_altaicaENSPTIP0000002215898.493497.5518
ENSG00000067225homo_sapiensENSP0000033498377.966174.7646rattus_norvegicusENSRNOP0000009397191.189487.4449
ENSG00000067225homo_sapiensENSP0000033498394.726993.7853rattus_norvegicusENSRNOP0000006750797.859996.8872
ENSG00000067225homo_sapiensENSP0000033498396.610293.9736prolemur_simusENSPSMP0000001779896.610293.9736
ENSG00000067225homo_sapiensENSP0000033498376.082971.7514microtus_ochrogasterENSMOCP0000001889682.44977.7551
ENSG00000067225homo_sapiensENSP0000033498376.271275.7062microtus_ochrogasterENSMOCP0000000357398.30197.5728
ENSG00000067225homo_sapiensENSP0000033498389.077285.4991microtus_ochrogasterENSMOCP0000000723693.849290.0794
ENSG00000067225homo_sapiensENSP0000033498380.037779.2844microtus_ochrogasterENSMOCP0000001690095.291594.3946
ENSG00000067225homo_sapiensENSP0000033498394.915393.032microtus_ochrogasterENSMOCP0000001362097.297395.3668
ENSG00000067225homo_sapiensENSP0000033498384.180881.1676sorex_araneusENSSARP0000000870084.499181.4745
ENSG00000067225homo_sapiensENSP0000033498398.116896.6102peromyscus_maniculatus_bairdiiENSPEMP0000000481198.116896.6102
ENSG00000067225homo_sapiensENSP0000033498396.986893.7853bos_mutusENSBMUP0000001011644.550243.0796
ENSG00000067225homo_sapiensENSP0000033498360.45258.7571mus_spicilegusENSMSIP0000000383192.774690.1734
ENSG00000067225homo_sapiensENSP0000033498376.459574.3879cricetulus_griseus_chok1gshdENSCGRP0000102550893.981591.4352
ENSG00000067225homo_sapiensENSP0000033498392.843790.9604cricetulus_griseus_chok1gshdENSCGRP0000102198095.357893.4236
ENSG00000067225homo_sapiensENSP0000033498343.126240.678cricetulus_griseus_chok1gshdENSCGRP0000101287588.759783.7209
ENSG00000067225homo_sapiensENSP0000033498396.986893.9736pteropus_vampyrusENSPVAP0000000604896.986893.9736
ENSG00000067225homo_sapiensENSP0000033498398.305196.6102myotis_lucifugusENSMLUP0000000765198.490696.7924
ENSG00000067225homo_sapiensENSP0000033498383.804178.7194myotis_lucifugusENSMLUP0000001745490.263784.787
ENSG00000067225homo_sapiensENSP0000033498363.841857.2505myotis_lucifugusENSMLUP0000001928978.110670.0461
ENSG00000067225homo_sapiensENSP0000033498394.16289.2655vombatus_ursinusENSVURP0001002021581.833177.5777
ENSG00000067225homo_sapiensENSP0000033498396.986893.4087rhinolophus_ferrumequinumENSRFEP0001001651784.150381.0458
ENSG00000067225homo_sapiensENSP0000033498387.382384.7458neovison_visonENSNVIP0000000433192.890
ENSG00000067225homo_sapiensENSP0000033498398.681797.5518bos_taurusENSBTAP0000004461998.681797.5518
ENSG00000067225homo_sapiensENSP0000033498397.551896.0452heterocephalus_glaber_femaleENSHGLP0000005641585.197483.8816
ENSG00000067225homo_sapiensENSP0000033498310099.8117rhinopithecus_bietiENSRBIP0000004138695.503695.3237
ENSG00000067225homo_sapiensENSP0000033498399.058498.4934canis_lupus_dingoENSCAFP0002000807499.058498.4934
ENSG00000067225homo_sapiensENSP0000033498398.870198.1168sciurus_vulgarisENSSVLP0000501467898.870198.1168
ENSG00000067225homo_sapiensENSP0000033498393.785388.5122phascolarctos_cinereusENSPCIP0000002144893.433488.1801
ENSG00000067225homo_sapiensENSP0000033498389.642285.3107procavia_capensisENSPCAP0000000434590.322685.9583
ENSG00000067225homo_sapiensENSP0000033498398.681797.9284nannospalax_galiliENSNGAP0000002346398.681797.9284
ENSG00000067225homo_sapiensENSP0000033498398.681797.5518bos_grunniensENSBGRP0000002167698.681797.5518
ENSG00000067225homo_sapiensENSP0000033498396.045291.9021chinchilla_lanigeraENSCLAP0000001228495.864791.7293
ENSG00000067225homo_sapiensENSP0000033498396.986893.9736cervus_hanglu_yarkandensisENSCHYP0000003452996.986893.9736
ENSG00000067225homo_sapiensENSP0000033498399.058497.7401catagonus_wagneriENSCWAP0000000559599.058497.7401
ENSG00000067225homo_sapiensENSP0000033498399.058498.1168ictidomys_tridecemlineatusENSSTOP0000003087799.058498.1168
ENSG00000067225homo_sapiensENSP0000033498385.687485.4991otolemur_garnettiiENSOGAP0000000801397.014996.8017
ENSG00000067225homo_sapiensENSP0000033498399.623499.435cebus_imitatorENSCCAP0000001420998.144797.9592
ENSG00000067225homo_sapiensENSP0000033498361.958658.3804urocitellus_parryiiENSUPAP0001000482393.732288.3191
ENSG00000067225homo_sapiensENSP0000033498398.681797.3635moschus_moschiferusENSMMSP0000000580098.681797.3635
ENSG00000067225homo_sapiensENSP0000033498399.43599.0584rhinopithecus_roxellanaENSRROP0000000005397.41797.048
ENSG00000067225homo_sapiensENSP0000033498399.43599.2467rhinopithecus_roxellanaENSRROP0000002998094.96494.7842
ENSG00000067225homo_sapiensENSP0000033498396.421893.7853mus_pahariMGP_PahariEiJ_P002380496.421893.7853
ENSG00000067225homo_sapiensENSP0000033498398.681798.4934propithecus_coquereliENSPCOP0000002389998.681798.4934
ENSG00000067225homo_sapiensENSP0000033498374.952959.1337caenorhabditis_elegansF25H5.3e.143.592634.3921
ENSG00000067225homo_sapiensENSP0000033498370.809854.8023caenorhabditis_elegansZK593.1a.173.009756.5049
ENSG00000067225homo_sapiensENSP0000033498376.647863.2768drosophila_melanogasterFBpp008361176.360263.0394
ENSG00000067225homo_sapiensENSP0000033498380.037768.9266ciona_intestinalisENSCINP0000000855779.58868.5393
ENSG00000067225homo_sapiensENSP0000033498391.337182.8625petromyzon_marinusENSPMAP0000000023389.814881.4815
ENSG00000067225homo_sapiensENSP0000033498382.297670.4331eptatretus_burgeriENSEBUP0000000390783.079871.1027
ENSG00000067225homo_sapiensENSP0000033498387.570678.3428eptatretus_burgeriENSEBUP0000002053287.570678.3428
ENSG00000067225homo_sapiensENSP0000033498389.077279.4727callorhinchus_miliiENSCMIP0000002703682.982574.0351
ENSG00000067225homo_sapiensENSP0000033498390.583884.1808latimeria_chalumnaeENSLACP0000000663589.239382.9314
ENSG00000067225homo_sapiensENSP0000033498393.408786.8173lepisosteus_oculatusENSLOCP0000001862289.530783.213
ENSG00000067225homo_sapiensENSP0000033498376.271266.4783clupea_harengusENSCHAP0000002037871.681462.4779
ENSG00000067225homo_sapiensENSP0000033498387.758978.5311clupea_harengusENSCHAP0000000786670.075262.7068
ENSG00000067225homo_sapiensENSP0000033498387.947377.0245danio_rerioENSDARP0000015050388.113277.1698
ENSG00000067225homo_sapiensENSP0000033498390.583881.9209danio_rerioENSDARP0000014034690.413581.7669
ENSG00000067225homo_sapiensENSP0000033498388.700677.5895carassius_auratusENSCARP0000001912482.19971.9023
ENSG00000067225homo_sapiensENSP0000033498389.642282.1092carassius_auratusENSCARP0000000885286.545579.2727
ENSG00000067225homo_sapiensENSP0000033498388.700677.7778carassius_auratusENSCARP0000009372986.10675.5027
ENSG00000067225homo_sapiensENSP0000033498390.395582.8625carassius_auratusENSCARP0000007194183.04576.1246
ENSG00000067225homo_sapiensENSP0000033498385.875776.8362astyanax_mexicanusENSAMXP0000004220777.157469.0355
ENSG00000067225homo_sapiensENSP0000033498391.337183.0508astyanax_mexicanusENSAMXP0000004276076.984170
ENSG00000067225homo_sapiensENSP0000033498386.06476.4595ictalurus_punctatusENSIPUP0000002598686.226476.6038
ENSG00000067225homo_sapiensENSP0000033498390.018882.6742ictalurus_punctatusENSIPUP0000001569176.972670.6924
ENSG00000067225homo_sapiensENSP0000033498389.077280.9793esox_luciusENSELUP0000004620781.975774.5234
ENSG00000067225homo_sapiensENSP0000033498387.570678.3428esox_luciusENSELUP0000005365381.722373.1107
ENSG00000067225homo_sapiensENSP0000033498389.830582.2976electrophorus_electricusENSEEEP0000003403680.574373.8176
ENSG00000067225homo_sapiensENSP0000033498386.62978.7194electrophorus_electricusENSEEEP0000003925283.032575.4513
ENSG00000067225homo_sapiensENSP0000033498389.642282.1092oncorhynchus_kisutchENSOKIP0000506787374.725368.4458
ENSG00000067225homo_sapiensENSP0000033498389.265581.1676oncorhynchus_kisutchENSOKIP0000504583979.530272.3154
ENSG00000067225homo_sapiensENSP0000033498383.239274.0113oncorhynchus_kisutchENSOKIP0000501685177.816969.1901
ENSG00000067225homo_sapiensENSP0000033498389.830582.1092oncorhynchus_mykissENSOMYP0000007510074.882368.4458
ENSG00000067225homo_sapiensENSP0000033498389.453981.3559oncorhynchus_mykissENSOMYP0000010283476.489569.5652
ENSG00000067225homo_sapiensENSP0000033498389.642282.1092salmo_salarENSSSAP0000009437873.798467.5969
ENSG00000067225homo_sapiensENSP0000033498389.265581.1676salmo_salarENSSSAP0000001483271.601265.1057
ENSG00000067225homo_sapiensENSP0000033498388.700680.791salmo_salarENSSSAP0000005161282.776875.3954
ENSG00000067225homo_sapiensENSP0000033498343.126238.0414salmo_salarENSSSAP0000003361478.15768.942
ENSG00000067225homo_sapiensENSP0000033498389.077281.9209salmo_truttaENSSTUP0000009086973.447267.5466
ENSG00000067225homo_sapiensENSP0000033498388.700680.791salmo_truttaENSSTUP0000010159582.342775
ENSG00000067225homo_sapiensENSP0000033498389.077281.1676salmo_truttaENSSTUP0000002715574.605767.9811
ENSG00000067225homo_sapiensENSP0000033498359.133751.7891gadus_morhuaENSGMOP0000003999366.384858.1395
ENSG00000067225homo_sapiensENSP0000033498389.265579.8493gadus_morhuaENSGMOP0000004825574.294766.4577
ENSG00000067225homo_sapiensENSP0000033498389.077281.3559fundulus_heteroclitusENSFHEP0000002098389.245381.5094
ENSG00000067225homo_sapiensENSP0000033498388.323977.9661fundulus_heteroclitusENSFHEP0000000828988.490678.1132
ENSG00000067225homo_sapiensENSP0000033498389.830581.9209poecilia_reticulataENSPREP0000000839878.583271.6639
ENSG00000067225homo_sapiensENSP0000033498387.382376.6478poecilia_reticulataENSPREP0000002353387.547276.7924
ENSG00000067225homo_sapiensENSP0000033498387.570677.5895xiphophorus_maculatusENSXMAP0000002982383.482973.9677
ENSG00000067225homo_sapiensENSP0000033498389.265580.9793xiphophorus_maculatusENSXMAP0000002117785.559677.6173
ENSG00000067225homo_sapiensENSP0000033498388.135677.2128oryzias_latipesENSORLP0000000622488.301977.3585
ENSG00000067225homo_sapiensENSP0000033498390.395582.4859oryzias_latipesENSORLP0000001664187.272779.6364
ENSG00000067225homo_sapiensENSP0000033498386.252477.9661cyclopterus_lumpusENSCLMP0000502528786.415178.1132
ENSG00000067225homo_sapiensENSP0000033498387.382376.8362cyclopterus_lumpusENSCLMP0000504474378.114568.6869
ENSG00000067225homo_sapiensENSP0000033498388.888979.8493oreochromis_niloticusENSONIP0000004140286.924578.0847
ENSG00000067225homo_sapiensENSP0000033498389.453982.2976oreochromis_niloticusENSONIP0000007052279.69873.3222
ENSG00000067225homo_sapiensENSP0000033498389.077281.9209haplochromis_burtoniENSHBUP0000000072579.629673.2323
ENSG00000067225homo_sapiensENSP0000033498388.700680.0377haplochromis_burtoniENSHBUP0000002291188.867980.1887
ENSG00000067225homo_sapiensENSP0000033498389.077281.9209astatotilapia_callipteraENSACLP0000002353485.379178.5199
ENSG00000067225homo_sapiensENSP0000033498386.817377.9661astatotilapia_callipteraENSACLP0000001041983.514575
ENSG00000067225homo_sapiensENSP0000033498383.804174.0113sparus_aurataENSSAUP0001003826870.411462.1835
ENSG00000067225homo_sapiensENSP0000033498390.018880.9793sparus_aurataENSSAUP0001002770280.201372.1477
ENSG00000067225homo_sapiensENSP0000033498385.122476.2712lates_calcariferENSLCAP0001001742685.931676.9962
ENSG00000067225homo_sapiensENSP0000033498390.395582.2976lates_calcariferENSLCAP0001004001184.358576.8014
ENSG00000067225homo_sapiensENSP0000033498394.538689.6422xenopus_tropicalisENSXETP0000005344395.256290.3226
ENSG00000067225homo_sapiensENSP0000033498394.538689.6422chrysemys_picta_belliiENSCPBP0000000807695.256290.3226
ENSG00000067225homo_sapiensENSP0000033498395.291989.8305sphenodon_punctatusENSSPUP0000001152191.83386.5699
ENSG00000067225homo_sapiensENSP0000033498395.291990.2072crocodylus_porosusENSCPRP0000500805095.471790.3774
ENSG00000067225homo_sapiensENSP0000033498394.538690.2072laticauda_laticaudataENSLLTP0000000125395.437391.0646
ENSG00000067225homo_sapiensENSP0000033498395.103690.5838notechis_scutatusENSNSUP0000002718196.007691.4449
ENSG00000067225homo_sapiensENSP0000033498394.726990.2072pseudonaja_textilisENSPTXP0000001915995.627491.0646
ENSG00000067225homo_sapiensENSP0000033498394.350389.8305anas_platyrhynchos_platyrhynchosENSAPLP0000000072991.090986.7273
ENSG00000067225homo_sapiensENSP0000033498393.973689.2655gallus_gallusENSGALP0001003030272.005868.3983
ENSG00000067225homo_sapiensENSP0000033498386.817381.5443meleagris_gallopavoENSMGAP0000000116781.16276.2324
ENSG00000067225homo_sapiensENSP0000033498393.220388.5122serinus_canariaENSSCAP0000002248189.511884.991
ENSG00000067225homo_sapiensENSP0000033498394.350390.2072parus_majorENSPMJP0000000923391.090987.0909
ENSG00000067225homo_sapiensENSP0000033498393.59787.9473anolis_carolinensisENSACAP0000001126994.307488.6148
ENSG00000067225homo_sapiensENSP0000033498388.700679.4727neolamprologus_brichardiENSNBRP0000000324484.257675.492
ENSG00000067225homo_sapiensENSP0000033498389.077281.9209neolamprologus_brichardiENSNBRP0000001308779.629673.2323
ENSG00000067225homo_sapiensENSP0000033498394.915390.5838naja_najaENSNNAP0000002604095.817591.4449
ENSG00000067225homo_sapiensENSP0000033498391.148887.194podarcis_muralisENSPMRP0000002739894.34790.2534
ENSG00000067225homo_sapiensENSP0000033498393.220388.1356geospiza_fortisENSGFOP0000000046090.328585.4015
ENSG00000067225homo_sapiensENSP0000033498392.843787.5706taeniopygia_guttataENSTGUP0000003719285.739180.8696
ENSG00000067225homo_sapiensENSP0000033498393.408786.629erpetoichthys_calabaricusENSECRP0000002057192.883986.1423
ENSG00000067225homo_sapiensENSP0000033498389.453980.4143kryptolebias_marmoratusENSKMAP0000002360575.516767.8855
ENSG00000067225homo_sapiensENSP0000033498388.135677.7778kryptolebias_marmoratusENSKMAP0000000125080.968971.4533
ENSG00000067225homo_sapiensENSP0000033498394.915390.7721salvator_merianaeENSSMRP0000002900795.635791.4611
ENSG00000067225homo_sapiensENSP0000033498390.207282.1092oryzias_javanicusENSOJAP0000004117777.009670.0965
ENSG00000067225homo_sapiensENSP0000033498388.323977.4011oryzias_javanicusENSOJAP0000001838987.174776.3941
ENSG00000067225homo_sapiensENSP0000033498383.050876.0829amphilophus_citrinellusENSACIP0000000450490.368982.7869
ENSG00000067225homo_sapiensENSP0000033498388.700680.0377amphilophus_citrinellusENSACIP0000002245388.867980.1887
ENSG00000067225homo_sapiensENSP0000033498388.512280.4143dicentrarchus_labraxENSDLAP0000502763479.66172.3729
ENSG00000067225homo_sapiensENSP0000033498388.700679.8493dicentrarchus_labraxENSDLAP0000502140487.709578.9572
ENSG00000067225homo_sapiensENSP0000033498382.862573.823amphiprion_perculaENSAPEP0000000104480.733971.9266
ENSG00000067225homo_sapiensENSP0000033498390.207282.2976amphiprion_perculaENSAPEP0000001275485.996478.456
ENSG00000067225homo_sapiensENSP0000033498388.135676.8362oryzias_sinensisENSOSIP0000000798482.539771.9577
ENSG00000067225homo_sapiensENSP0000033498390.018882.1092oryzias_sinensisENSOSIP0000000918880.879973.7733
ENSG00000067225homo_sapiensENSP0000033498394.16288.8889pelodiscus_sinensisENSPSIP0000000877894.16288.8889
ENSG00000067225homo_sapiensENSP0000033498384.180880.226gopherus_evgoodeiENSGEVP0000502447694.303889.8734
ENSG00000067225homo_sapiensENSP0000033498394.538690.0188chelonoidis_abingdoniiENSCABP0000001365690.777686.4376
ENSG00000067225homo_sapiensENSP0000033498387.382378.3428seriola_dumeriliENSSDUP0000000756188.38179.2381
ENSG00000067225homo_sapiensENSP0000033498388.700679.8493seriola_dumeriliENSSDUP0000003026388.867980
ENSG00000067225homo_sapiensENSP0000033498390.772180.9793cottoperca_gobioENSCGOP0000003705776.265868.038
ENSG00000067225homo_sapiensENSP0000033498383.804176.0829cottoperca_gobioENSCGOP0000004926774.290567.4457
ENSG00000067225homo_sapiensENSP0000033498394.350389.6422struthio_camelus_australisENSSCUP0000000649489.464385
ENSG00000067225homo_sapiensENSP0000033498393.973689.2655anser_brachyrhynchusENSABRP0000002317088.162583.7456
ENSG00000067225homo_sapiensENSP0000033498390.207281.9209gasterosteus_aculeatusENSGACP0000002193490.037681.7669
ENSG00000067225homo_sapiensENSP0000033498387.19477.9661gasterosteus_aculeatusENSGACP0000000859084.798575.8242
ENSG00000067225homo_sapiensENSP0000033498388.700678.7194cynoglossus_semilaevisENSCSEP0000002034588.867978.8679
ENSG00000067225homo_sapiensENSP0000033498390.395583.4275cynoglossus_semilaevisENSCSEP0000001213890.225683.2707
ENSG00000067225homo_sapiensENSP0000033498387.758977.7778poecilia_formosaENSPFOP0000001280887.924577.9245
ENSG00000067225homo_sapiensENSP0000033498389.453981.5443poecilia_formosaENSPFOP0000001673289.622681.6981
ENSG00000067225homo_sapiensENSP0000033498388.888980.791myripristis_murdjanENSMMDP0000505452782.952575.3954
ENSG00000067225homo_sapiensENSP0000033498388.323978.9077myripristis_murdjanENSMMDP0000500187888.157978.7594
ENSG00000067225homo_sapiensENSP0000033498388.512280.4143sander_luciopercaENSSLUP0000001722879.93272.619
ENSG00000067225homo_sapiensENSP0000033498388.135679.661sander_luciopercaENSSLUP0000000278681.961574.0806
ENSG00000067225homo_sapiensENSP0000033498394.350390.5838strigops_habroptilaENSSHBP0000501279291.090987.4545
ENSG00000067225homo_sapiensENSP0000033498388.323978.9077amphiprion_ocellarisENSAOCP0000000248488.490679.0566
ENSG00000067225homo_sapiensENSP0000033498390.395582.2976amphiprion_ocellarisENSAOCP0000002598189.719681.6822
ENSG00000067225homo_sapiensENSP0000033498394.538690.0188terrapene_carolina_triunguisENSTMTP0000001836894.538690.0188
ENSG00000067225homo_sapiensENSP0000033498384.369176.4595hucho_huchoENSHHUP0000006011473.083266.2317
ENSG00000067225homo_sapiensENSP0000033498389.453982.2976hucho_huchoENSHHUP0000008569773.643467.7519
ENSG00000067225homo_sapiensENSP0000033498380.79171.5631hucho_huchoENSHHUP0000002197786.317976.4588
ENSG00000067225homo_sapiensENSP0000033498387.758978.5311betta_splendensENSBSLP0000003425278.98370.678
ENSG00000067225homo_sapiensENSP0000033498389.642281.5443betta_splendensENSBSLP0000004271185.765878.018
ENSG00000067225homo_sapiensENSP0000033498391.148883.4275pygocentrus_nattereriENSPNAP0000002252790.977483.2707
ENSG00000067225homo_sapiensENSP0000033498384.180873.6347pygocentrus_nattereriENSPNAP0000000918186.127275.3372
ENSG00000067225homo_sapiensENSP0000033498388.700679.4727anabas_testudineusENSATEP0000002202681.067172.6334
ENSG00000067225homo_sapiensENSP0000033498390.207282.4859anabas_testudineusENSATEP0000000303075.55269.0852
ENSG00000067225homo_sapiensENSP0000033498380.414368.9266ciona_savignyiENSCSAVP0000001851980.871269.3182
ENSG00000067225homo_sapiensENSP0000033498363.841847.8343saccharomyces_cerevisiaeYAL038W67.850.8
ENSG00000067225homo_sapiensENSP0000033498362.146945.7627saccharomyces_cerevisiaeYOR347C65.217448.0237
ENSG00000067225homo_sapiensENSP0000033498388.512278.7194seriola_lalandi_dorsalisENSSLDP0000000992888.679278.8679
ENSG00000067225homo_sapiensENSP0000033498390.018881.1676seriola_lalandi_dorsalisENSSLDP0000002068575.752868.3043
ENSG00000067225homo_sapiensENSP0000033498387.382377.7778labrus_bergyltaENSLBEP0000001775287.547277.9245
ENSG00000067225homo_sapiensENSP0000033498382.109273.4463labrus_bergyltaENSLBEP0000001413974.529966.6667
ENSG00000067225homo_sapiensENSP0000033498388.700679.661pundamilia_nyerereiENSPNYP0000002881688.867979.8113
ENSG00000067225homo_sapiensENSP0000033498389.077281.9209pundamilia_nyerereiENSPNYP0000001526789.077281.9209
ENSG00000067225homo_sapiensENSP0000033498390.207280.6026mastacembelus_armatusENSMAMP0000004340387.090977.8182
ENSG00000067225homo_sapiensENSP0000033498387.758979.4727mastacembelus_armatusENSMAMP0000006740275.040367.9549
ENSG00000067225homo_sapiensENSP0000033498390.018881.1676stegastes_partitusENSSPAP0000001052989.849681.015
ENSG00000067225homo_sapiensENSP0000033498388.323979.096stegastes_partitusENSSPAP0000001301988.490679.2453
ENSG00000067225homo_sapiensENSP0000033498389.642282.1092oncorhynchus_tshawytschaENSOTSP0000509176774.725368.4458
ENSG00000067225homo_sapiensENSP0000033498389.642282.1092oncorhynchus_tshawytschaENSOTSP0000506888574.725368.4458
ENSG00000067225homo_sapiensENSP0000033498346.51641.8079oncorhynchus_tshawytschaENSOTSP0000508128386.971878.169
ENSG00000067225homo_sapiensENSP0000033498389.453981.3559oncorhynchus_tshawytschaENSOTSP0000502901983.774376.1905
ENSG00000067225homo_sapiensENSP0000033498388.135677.9661acanthochromis_polyacanthusENSAPOP0000000880388.301978.1132
ENSG00000067225homo_sapiensENSP0000033498390.772182.1092acanthochromis_polyacanthusENSAPOP0000001592490.262281.6479
ENSG00000067225homo_sapiensENSP0000033498393.220387.7589aquila_chrysaetos_chrysaetosENSACCP0002000368579.710175.0403
ENSG00000067225homo_sapiensENSP0000033498384.369174.3879nothobranchius_furzeriENSNFUP0001504101878.18568.9354
ENSG00000067225homo_sapiensENSP0000033498390.207281.1676nothobranchius_furzeriENSNFUP0001501971675.314567.7673
ENSG00000067225homo_sapiensENSP0000033498384.557474.3879cyprinodon_variegatusENSCVAP0000000656183.925273.8318
ENSG00000067225homo_sapiensENSP0000033498389.077281.1676cyprinodon_variegatusENSCVAP0000001591675.198768.5215
ENSG00000067225homo_sapiensENSP0000033498389.453980.6026denticeps_clupeoidesENSDCDP0000003676781.335673.2877
ENSG00000067225homo_sapiensENSP0000033498334.651631.4501denticeps_clupeoidesENSDCDP0000003370688.038379.9043
ENSG00000067225homo_sapiensENSP0000033498387.947378.9077denticeps_clupeoidesENSDCDP0000006118876.182768.3524
ENSG00000067225homo_sapiensENSP0000033498389.830581.5443larimichthys_croceaENSLCRP0000506276484.724776.9094
ENSG00000067225homo_sapiensENSP0000033498387.947377.9661larimichthys_croceaENSLCRP0000505554081.500972.2513
ENSG00000067225homo_sapiensENSP0000033498388.512280.4143takifugu_rubripesENSTRUP0000008358181.314973.8754
ENSG00000067225homo_sapiensENSP0000033498385.875777.2128takifugu_rubripesENSTRUP0000008070880.994772.8242
ENSG00000067225homo_sapiensENSP0000033498394.16289.8305ficedula_albicollisENSFALP0000002012390.909186.7273
ENSG00000067225homo_sapiensENSP0000033498387.570678.7194hippocampus_comesENSHCOP0000001373088.068279.1667
ENSG00000067225homo_sapiensENSP0000033498390.207282.6742hippocampus_comesENSHCOP0000001722175.314569.0252
ENSG00000067225homo_sapiensENSP0000033498388.512277.9661cyprinus_carpio_carpioENSCCRP0000010248180.204870.6485
ENSG00000067225homo_sapiensENSP0000033498390.960483.0508cyprinus_carpio_carpioENSCCRP0000017307281.450374.3676
ENSG00000067225homo_sapiensENSP0000033498390.583882.2976cyprinus_carpio_carpioENSCCRP0000017410576.714569.697
ENSG00000067225homo_sapiensENSP0000033498389.077277.9661cyprinus_carpio_carpioENSCCRP0000016380579.629669.697
ENSG00000067225homo_sapiensENSP0000033498394.350389.2655coturnix_japonicaENSCJPP0000500824991.926686.9725
ENSG00000067225homo_sapiensENSP0000033498390.207282.4859poecilia_latipinnaENSPLAP0000002890390.377482.6415
ENSG00000067225homo_sapiensENSP0000033498388.135677.7778poecilia_latipinnaENSPLAP0000001635088.301977.9245
ENSG00000067225homo_sapiensENSP0000033498382.674272.1281sinocyclocheilus_grahamiENSSGRP0000002427185.077574.2248
ENSG00000067225homo_sapiensENSP0000033498389.642280.791sinocyclocheilus_grahamiENSSGRP0000009691483.950675.6614
ENSG00000067225homo_sapiensENSP0000033498387.19477.2128sinocyclocheilus_grahamiENSSGRP0000009215582.23872.8242
ENSG00000067225homo_sapiensENSP0000033498382.485975.8945sinocyclocheilus_grahamiENSSGRP0000004783085.048578.2524
ENSG00000067225homo_sapiensENSP0000033498388.888981.9209maylandia_zebraENSMZEP0000500956985.198678.5199
ENSG00000067225homo_sapiensENSP0000033498388.700679.8493maylandia_zebraENSMZEP0000500610588.867980
ENSG00000067225homo_sapiensENSP0000033498388.700679.096tetraodon_nigroviridisENSTNIP0000001671388.700679.096
ENSG00000067225homo_sapiensENSP0000033498390.395581.5443tetraodon_nigroviridisENSTNIP0000000265689.053880.334
ENSG00000067225homo_sapiensENSP0000033498388.888979.8493paramormyrops_kingsleyaeENSPKIP0000000107373.06565.6347
ENSG00000067225homo_sapiensENSP0000033498390.395582.2976scleropages_formosusENSSFOP0001503807284.210576.6667
ENSG00000067225homo_sapiensENSP0000033498392.278786.2524leptobrachium_leishanenseENSLLEP0000004231385.069479.5139
ENSG00000067225homo_sapiensENSP0000033498388.135679.096scophthalmus_maximusENSSMAP0000004893082.105373.6842
ENSG00000067225homo_sapiensENSP0000033498389.642280.791scophthalmus_maximusENSSMAP0000001376788.475879.7398
ENSG00000067225homo_sapiensENSP0000033498390.583882.4859oryzias_melastigmaENSOMEP0000001375486.823179.0614
ENSG00000067225homo_sapiensENSP0000033498388.135677.4011oryzias_melastigmaENSOMEP0000003013878.39268.8442

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000287enables magnesium ion binding1IEAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1ISSHomo_sapiens(9606)Function
GO:0004713enables protein tyrosine kinase activity1IEAHomo_sapiens(9606)Function
GO:0004743enables pyruvate kinase activity3IBA,IDA,TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634located_in nucleus2HDA,IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1HDAHomo_sapiens(9606)Component
GO:0005791located_in rough endoplasmic reticulum1ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol3IDA,NAS,TASHomo_sapiens(9606)Component
GO:0005929located_in cilium1IEAHomo_sapiens(9606)Component
GO:0006096involved_in glycolytic process1IBAHomo_sapiens(9606)Process
GO:0012501involved_in programmed cell death1IDAHomo_sapiens(9606)Process
GO:0016310involved_in phosphorylation1IEAHomo_sapiens(9606)Process
GO:0023026enables MHC class II protein complex binding1HDAHomo_sapiens(9606)Function
GO:0030955enables potassium ion binding1IEAHomo_sapiens(9606)Function
GO:0031982located_in vesicle1HDAHomo_sapiens(9606)Component
GO:0032869involved_in cellular response to insulin stimulus1IBAHomo_sapiens(9606)Process
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0061621involved_in canonical glycolysis1IEAHomo_sapiens(9606)Process
GO:0062023located_in collagen-containing extracellular matrix1HDAHomo_sapiens(9606)Component
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:1903561located_in extracellular vesicle1HDAHomo_sapiens(9606)Component
GO:1903672involved_in positive regulation of sprouting angiogenesis1IMPHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component
GO:2000767involved_in positive regulation of cytoplasmic translation1ISSHomo_sapiens(9606)Process

Expression