RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq

Ensembl ID	ENSG00000065135	Gene ID	2773	Accession	4387
Symbol	GNAI3	Alias	87U6;HG1A;ARCND1;ARCODS	Full Name	G protein subunit alpha i3
Status	Confidence	Length	51581 bases	Strand	Plus strand
Position	1 : 109548615 - 109600195	RNA binding domain	N.A.
Summary	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
GNAI3-201	ENST00000369851	9044	354aa	ENSP00000358867

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
44517	Platelet Function Tests	2.2204460E-016	-
105096	Depressive Disorder	1E-6	20125088

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000139	colocalizes_with Golgi membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0001664	enables G protein-coupled receptor binding	1	IBA	Homo_sapiens(9606)	Function
GO:0003924	enables GTPase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005525	enables GTP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005765	located_in lysosomal membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0005789	colocalizes_with endoplasmic reticulum membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0005813	located_in centrosome	1	IDA	Homo_sapiens(9606)	Component
GO:0005834	part_of heterotrimeric G-protein complex	1	IBA	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0007049	involved_in cell cycle	1	IEA	Homo_sapiens(9606)	Process
GO:0007188	involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway	1	IBA	Homo_sapiens(9606)	Process
GO:0007193	involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0007194	involved_in negative regulation of adenylate cyclase activity	1	TAS	Homo_sapiens(9606)	Process
GO:0007212	involved_in dopamine receptor signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016239	involved_in positive regulation of macroautophagy	1	IMP	Homo_sapiens(9606)	Process
GO:0019003	enables GDP binding	1	IDA	Homo_sapiens(9606)	Function
GO:0030496	located_in midbody	1	IDA	Homo_sapiens(9606)	Component
GO:0031683	enables G-protein beta/gamma-subunit complex binding	1	IBA	Homo_sapiens(9606)	Function
GO:0046039	involved_in GTP metabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051301	involved_in cell division	1	IDA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component