Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000062370 Gene ID 7771 Accession 12892
Symbol ZNF112 Alias ZFP112;ZNF228 Full Name zinc finger protein 112
Status Confidence Length 40663 bases Strand Minus strand
Position 19 : 44326555 - 44367217 RNA binding domain zf-met
Summary Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000346305 zf-met PF12874 3.4e-15 1
ENSP00000337081 zf-met PF12874 3.8e-15 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZNF112-202 ENST00000354340 3660 907aa ENSP00000346305
ZNF112-201 ENST00000337401 3321 913aa ENSP00000337081
ZNF112-203 ENST00000587909 569 151aa ENSP00000466797
ZNF112-205 ENST00000590687 577 149aa ENSP00000467064
ZNF112-206 ENST00000592151 534 54aa ENSP00000464862
ZNF112-204 ENST00000588057 558 146aa ENSP00000467994

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
13263Lupus Erythematosus, Systemic5.38E-718204446
84717Myopia, Degenerative3E-1523049088

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0001228enables DNA-binding transcription activator activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression