Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_242 DataSet_01_395 DataSet_02_34

Description

Ensembl ID ENSG00000055917 Gene ID 23369 Accession 14958
Symbol PUM2 Alias PUMH2;PUML2 Full Name pumilio RNA binding family member 2
Status Confidence Length 103544 bases Strand Minus strand
Position 2 : 20248691 - 20352234 RNA binding domain PUF
Summary This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000409905 PUF PF00806 1.7e-86 1
ENSP00000409905 PUF PF00806 1.7e-86 2
ENSP00000409905 PUF PF00806 1.7e-86 3
ENSP00000409905 PUF PF00806 1.7e-86 4
ENSP00000409905 PUF PF00806 1.7e-86 5
ENSP00000409905 PUF PF00806 1.7e-86 6
ENSP00000409905 PUF PF00806 1.7e-86 7
ENSP00000409905 PUF PF00806 1.7e-86 8
ENSP00000338173 PUF PF00806 9.9e-86 1
ENSP00000338173 PUF PF00806 9.9e-86 2
ENSP00000338173 PUF PF00806 9.9e-86 3
ENSP00000338173 PUF PF00806 9.9e-86 4
ENSP00000338173 PUF PF00806 9.9e-86 5
ENSP00000338173 PUF PF00806 9.9e-86 6
ENSP00000338173 PUF PF00806 9.9e-86 7
ENSP00000338173 PUF PF00806 9.9e-86 8
ENSP00000354370 PUF PF00806 9.9e-86 1
ENSP00000354370 PUF PF00806 9.9e-86 2
ENSP00000354370 PUF PF00806 9.9e-86 3
ENSP00000354370 PUF PF00806 9.9e-86 4
ENSP00000354370 PUF PF00806 9.9e-86 5
ENSP00000354370 PUF PF00806 9.9e-86 6
ENSP00000354370 PUF PF00806 9.9e-86 7
ENSP00000354370 PUF PF00806 9.9e-86 8
ENSP00000516061 PUF PF00806 2.6e-84 1
ENSP00000516061 PUF PF00806 2.6e-84 2
ENSP00000516061 PUF PF00806 2.6e-84 3
ENSP00000516061 PUF PF00806 2.6e-84 4
ENSP00000516061 PUF PF00806 2.6e-84 5
ENSP00000516061 PUF PF00806 2.6e-84 6
ENSP00000516061 PUF PF00806 2.6e-84 7
ENSP00000516061 PUF PF00806 2.6e-84 8

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36527344 Mutant Allele of CD44 (rs8193C>T) and Pum2 Regulatory Element as A Prognosis Factor of Prostate Neoplasms: A Case-Control and In Silico Studies. Mohammadkazem Heydari 2022-12-01 Cell journal
32870730 Regulation and Function of RNA Pseudouridylation in Human Cells. K Erin Borchardt 2020-11-23 Annual review of genetics
36072004 RNA binding protein PUM2 promotes hepatocellular carcinoma proliferation and apoptosis via binding to the 3'UTR of BTG3. Zhenhua Liu 2022-10-01 Oncology letters
33576437 Downregulated expression levels of USP46 promote the resistance of ovarian cancer to cisplatin and are regulated by PUM2. Lei Xu 2021-04-01 Molecular medicine reports
29666150 Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence. Ki-Jun Yoon 2018-06-04 The Journal of cell biology
35304463 WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration. Gaocai Li 2022-03-18 Nature communications
31078383 A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins. Inga Jarmoskaite 2019-06-06 Molecular cell
33557274 Genomic and Epigenomic Profile of Uterine Smooth Muscle Tumors of Uncertain Malignant Potential (STUMPs) Revealed Similarities and Differences with Leiomyomas and Leiomyosarcomas. Donatella Conconi 2021-02-04 International journal of molecular sciences
12511597 Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. L Frederick Moore 2003-01-21 Proceedings of the National Academy of Sciences of the United States of America
33066461 Intimate Relations-Mitochondria and Ageing. Michael Webb 2020-10-14 International journal of molecular sciences
30197756 SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma. Mikolaj Damian Janecki 2018-08-21 Oncotarget
12459267 Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins. S Danislav Spassov 2002-10-16 Gene
30316580 Post-transcriptional Regulatory Functions of Mammalian Pumilio Proteins. C Aaron Goldstrohm 2018-12-01 Trends in genetics : TIG
30084199 RNA-binding protein PUM2 suppresses osteosarcoma progression via partly and competitively binding to STARD13 3'UTR with miRNAs. Ruixi Hu 2018-12-01 Cell proliferation
31018129 An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration. N Brittany Flores 2019-04-23 Cell reports
30914482 Demonstration of protein cooperativity mediated by RNA structure using the human protein PUM2. R Winston Becker 2019-06-01 RNA (New York, N.Y.)
35927243 A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4. Christoph Sadée 2022-08-04 Nature communications
24997599 A protein-RNA specificity code enables targeted activation of an endogenous human transcript. T Zachary Campbell 2014-08-01 Nature structural & molecular biology
32316190 Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model. J Maciej Smialek 2020-04-16 Cells

Transcripts

Name Transcript ID bp Protein Translation ID
PUM2-201 ENST00000338086 6112 1064aa ENSP00000338173
PUM2-210 ENST00000704930 6126 1066aa ENSP00000516061
PUM2-202 ENST00000361078 6309 1064aa ENSP00000354370
PUM2-207 ENST00000440577 4352 876aa ENSP00000409905
PUM2-208 ENST00000442400 955 293aa ENSP00000387399
PUM2-203 ENST00000420234 562 No protein -
PUM2-205 ENST00000429419 547 40aa ENSP00000396727
PUM2-206 ENST00000432105 584 35aa ENSP00000408384
PUM2-209 ENST00000446940 525 35aa ENSP00000413515
PUM2-204 ENST00000424110 546 34aa ENSP00000395098

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
13897Myocardial Infarction4.4292985E-005-
14077Attention Deficit Disorder with Hyperactivity4.1600000E-00518937294

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000055917homo_sapiensENSP0000039172376.93670.4545homo_sapiensENSP0000035437085.902378.6654

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000055917homo_sapiensENSP0000035437098.778298.4962nomascus_leucogenysENSNLEP0000003382498.408298.1273
ENSG00000055917homo_sapiensENSP0000035437099.90699.906pan_paniscusENSPPAP0000000564199.812299.8122
ENSG00000055917homo_sapiensENSP0000035437099.90699.718pongo_abeliiENSPPYP0000001409099.625199.4377
ENSG00000055917homo_sapiensENSP0000035437099.90699.906pan_troglodytesENSPTRP0000002009199.812299.8122
ENSG00000055917homo_sapiensENSP0000035437099.90699.906gorilla_gorillaENSGGOP0000004839199.812299.8122
ENSG00000055917homo_sapiensENSP0000035437096.428694.3609ornithorhynchus_anatinusENSOANP0000005250497.159195.0758
ENSG00000055917homo_sapiensENSP0000035437093.79789.4737sarcophilus_harrisiiENSSHAP0000002308488.318684.2478
ENSG00000055917homo_sapiensENSP0000035437088.251983.7406notamacropus_eugeniiENSMEUP0000001514688.003783.5052
ENSG00000055917homo_sapiensENSP0000035437074.436173.4962choloepus_hoffmanniENSCHOP0000000405473.949673.0159
ENSG00000055917homo_sapiensENSP0000035437097.368495.3947dasypus_novemcinctusENSDNOP0000000523296.641894.6828
ENSG00000055917homo_sapiensENSP0000035437064.567763.1579erinaceus_europaeusENSEEUP0000000296464.446563.0394
ENSG00000055917homo_sapiensENSP0000035437076.221875echinops_telfairiENSETEP0000001436680.456479.1667
ENSG00000055917homo_sapiensENSP0000035437099.71899.5301callithrix_jacchusENSCJAP0000009368399.53199.3433
ENSG00000055917homo_sapiensENSP0000035437099.71899.6241cercocebus_atysENSCATP0000004244597.339497.2477
ENSG00000055917homo_sapiensENSP0000035437099.81299.6241macaca_fascicularisENSMFAP0000004553799.718399.5305
ENSG00000055917homo_sapiensENSP0000035437098.966298.4962macaca_mulattaENSMMUP0000003051292.287591.8493
ENSG00000055917homo_sapiensENSP0000035437099.81299.6241macaca_nemestrinaENSMNEP0000003270399.718399.5305
ENSG00000055917homo_sapiensENSP0000035437099.71899.6241papio_anubisENSPANP0000004960397.339497.2477
ENSG00000055917homo_sapiensENSP0000035437099.81299.718mandrillus_leucophaeusENSMLEP0000003008799.718399.6244
ENSG00000055917homo_sapiensENSP0000035437098.778298.1203tursiops_truncatusENSTTRP0000000461198.871198.2126
ENSG00000055917homo_sapiensENSP0000035437099.248198.6842vulpes_vulpesENSVVUP0000002007599.341598.777
ENSG00000055917homo_sapiensENSP0000035437098.778297.7444mus_spretusMGP_SPRETEiJ_P003334898.592997.561
ENSG00000055917homo_sapiensENSP0000035437099.060298.4962equus_asinusENSEASP0000501349098.967198.4038
ENSG00000055917homo_sapiensENSP0000035437097.932397.4624capra_hircusENSCHIP0000002543697.932397.4624
ENSG00000055917homo_sapiensENSP0000035437099.060298.0263loxodonta_africanaENSLAFP0000000777898.504797.4766
ENSG00000055917homo_sapiensENSP0000035437099.154198.5902panthera_leoENSPLOP0000000622699.247498.683
ENSG00000055917homo_sapiensENSP0000035437099.154198.4962ailuropoda_melanoleucaENSAMEP0000000302299.154198.4962
ENSG00000055917homo_sapiensENSP0000035437099.154198.4962bos_indicus_hybridENSBIXP0000502272299.247498.5889
ENSG00000055917homo_sapiensENSP0000035437099.342198.5902oryctolagus_cuniculusENSOCUP0000001538799.155798.4053
ENSG00000055917homo_sapiensENSP0000035437095.112894.5489equus_caballusENSECAP0000002906299.118598.5309
ENSG00000055917homo_sapiensENSP0000035437099.154198.5902canis_lupus_familiarisENSCAFP0084502610599.247498.683
ENSG00000055917homo_sapiensENSP0000035437099.154198.5902panthera_pardusENSPPRP0000002903599.247498.683
ENSG00000055917homo_sapiensENSP0000035437084.492583.8346marmota_marmota_marmotaENSMMMP0000002527297.823797.062
ENSG00000055917homo_sapiensENSP0000035437098.966298.4023balaenoptera_musculusENSBMSP0001001864298.873298.3099
ENSG00000055917homo_sapiensENSP0000035437098.966298.0263cavia_porcellusENSCPOP0000002155998.595597.6592
ENSG00000055917homo_sapiensENSP0000035437099.154198.5902felis_catusENSFCAP0000001758499.247498.683
ENSG00000055917homo_sapiensENSP0000035437074.624173.1203ursus_americanusENSUAMP0000001049293.30291.4219
ENSG00000055917homo_sapiensENSP0000035437094.172989.8496monodelphis_domesticaENSMODP0000004886585.276681.3617
ENSG00000055917homo_sapiensENSP0000035437099.060298.4962bison_bison_bisonENSBBBP0000002431699.060298.4962
ENSG00000055917homo_sapiensENSP0000035437098.966298.4023monodon_monocerosENSMMNP0001501202499.059398.4948
ENSG00000055917homo_sapiensENSP0000035437099.154198.6842sus_scrofaENSSSCP0000004243499.434598.9632
ENSG00000055917homo_sapiensENSP0000035437099.71899.4361microcebus_murinusENSMICP0000002774899.624499.3427
ENSG00000055917homo_sapiensENSP0000035437098.590297.8383octodon_degusENSODEP0000001047998.590297.8383
ENSG00000055917homo_sapiensENSP0000035437099.154198.4962jaculus_jaculusENSJJAP0000002025098.690498.0355
ENSG00000055917homo_sapiensENSP0000035437099.060298.5902ovis_aries_rambouilletENSOARP0002002335199.153398.683
ENSG00000055917homo_sapiensENSP0000035437099.248198.5902ursus_maritimusENSUMAP0000003217899.341598.683
ENSG00000055917homo_sapiensENSP0000035437065.319564.3797ochotona_princepsENSOPRP0000000181779.157278.0182
ENSG00000055917homo_sapiensENSP0000035437098.966298.3083delphinapterus_leucasENSDLEP0000000484099.059398.4007
ENSG00000055917homo_sapiensENSP0000035437098.966298.3083physeter_catodonENSPCTP0000502329099.059398.4007
ENSG00000055917homo_sapiensENSP0000035437098.778297.7444mus_caroliMGP_CAROLIEiJ_P003188598.592997.561
ENSG00000055917homo_sapiensENSP0000035437098.872297.7444mus_musculusENSMUSP0000012829298.686797.561
ENSG00000055917homo_sapiensENSP0000035437093.89192.4812dipodomys_ordiiENSDORP0000001076697.084595.6268
ENSG00000055917homo_sapiensENSP0000035437099.248198.5902mustela_putorius_furoENSMPUP0000001363199.341598.683
ENSG00000055917homo_sapiensENSP0000035437099.71899.6241aotus_nancymaaeENSANAP0000000802299.624499.5305
ENSG00000055917homo_sapiensENSP0000035437099.81299.718saimiri_boliviensis_boliviensisENSSBOP0000001069999.624899.531
ENSG00000055917homo_sapiensENSP0000035437098.966298.3083vicugna_pacosENSVPAP0000000469099.059398.4007
ENSG00000055917homo_sapiensENSP0000035437099.81299.718chlorocebus_sabaeusENSCSAP0000000435099.718399.6244
ENSG00000055917homo_sapiensENSP0000035437079.135378.8534tupaia_belangeriENSTBEP0000000757479.659479.3756
ENSG00000055917homo_sapiensENSP0000035437099.060298.1203mesocricetus_auratusENSMAUP0000000038998.874397.9362
ENSG00000055917homo_sapiensENSP0000035437098.966298.4023phocoena_sinusENSPSNP0000000777799.059398.4948
ENSG00000055917homo_sapiensENSP0000035437098.966298.3083camelus_dromedariusENSCDRP0000500766799.24698.5862
ENSG00000055917homo_sapiensENSP0000035437099.060298.7782carlito_syrichtaENSTSYP0000002003499.246798.9642
ENSG00000055917homo_sapiensENSP0000035437099.154198.5902panthera_tigris_altaicaENSPTIP0000002204999.247498.683
ENSG00000055917homo_sapiensENSP0000035437099.060297.9323rattus_norvegicusENSRNOP0000007459298.781697.657
ENSG00000055917homo_sapiensENSP0000035437099.530199.0602prolemur_simusENSPSMP0000000978499.436698.9671
ENSG00000055917homo_sapiensENSP0000035437098.872297.9323microtus_ochrogasterENSMOCP0000001409798.872297.9323
ENSG00000055917homo_sapiensENSP0000035437076.691775.9398sorex_araneusENSSARP0000000993980.394179.6059
ENSG00000055917homo_sapiensENSP0000035437099.060297.6504peromyscus_maniculatus_bairdiiENSPEMP0000000615098.874397.4672
ENSG00000055917homo_sapiensENSP0000035437099.060298.4962bos_mutusENSBMUP0000000724399.060298.4962
ENSG00000055917homo_sapiensENSP0000035437098.872297.8383mus_spicilegusENSMSIP0000000486998.872297.8383
ENSG00000055917homo_sapiensENSP0000035437099.060297.8383cricetulus_griseus_chok1gshdENSCGRP0000102826899.060297.8383
ENSG00000055917homo_sapiensENSP0000035437092.105391.5414pteropus_vampyrusENSPVAP0000000275794.049993.4741
ENSG00000055917homo_sapiensENSP0000035437098.590297.9323myotis_lucifugusENSMLUP0000000673298.497797.8404
ENSG00000055917homo_sapiensENSP0000035437095.582791.2594vombatus_ursinusENSVURP0001003113593.992689.7412
ENSG00000055917homo_sapiensENSP0000035437097.838397.0865rhinolophus_ferrumequinumENSRFEP0001000825995.242594.5105
ENSG00000055917homo_sapiensENSP0000035437099.154198.4962neovison_visonENSNVIP0000001678699.247498.5889
ENSG00000055917homo_sapiensENSP0000035437099.154198.4962bos_taurusENSBTAP0000006712499.247498.5889
ENSG00000055917homo_sapiensENSP000003543705.451134.9812heterocephalus_glaber_femaleENSHGLP0000004324084.05876.8116
ENSG00000055917homo_sapiensENSP0000035437099.71899.6241rhinopithecus_bietiENSRBIP0000004343799.624499.5305
ENSG00000055917homo_sapiensENSP0000035437097.744496.9925canis_lupus_dingoENSCAFP0002003312694.890594.1606
ENSG00000055917homo_sapiensENSP0000035437099.436198.8722sciurus_vulgarisENSSVLP0000503123499.529698.9652
ENSG00000055917homo_sapiensENSP0000035437082.330881.203sciurus_vulgarisENSSVLP0000501452798.096396.7525
ENSG00000055917homo_sapiensENSP0000035437096.146692.0113phascolarctos_cinereusENSPCIP0000002975395.429191.3246
ENSG00000055917homo_sapiensENSP0000035437068.98568.2331procavia_capensisENSPCAP0000000751968.726667.9775
ENSG00000055917homo_sapiensENSP0000035437075.18871.2406nannospalax_galiliENSNGAP0000001513788.593683.9424
ENSG00000055917homo_sapiensENSP0000035437098.590298.2143nannospalax_galiliENSNGAP0000001581298.68398.3067
ENSG00000055917homo_sapiensENSP0000035437099.060298.4962bos_grunniensENSBGRP0000003262399.060298.4962
ENSG00000055917homo_sapiensENSP0000035437099.154198.4023chinchilla_lanigeraENSCLAP0000000864698.782898.0337
ENSG00000055917homo_sapiensENSP0000035437096.616595.1128cervus_hanglu_yarkandensisENSCHYP0000000908895.895594.403
ENSG00000055917homo_sapiensENSP0000035437099.248198.7782catagonus_wagneriENSCWAP0000000485699.154998.6854
ENSG00000055917homo_sapiensENSP0000035437099.436198.9662ictidomys_tridecemlineatusENSSTOP0000000560999.436198.9662
ENSG00000055917homo_sapiensENSP0000035437088.157987.312otolemur_garnettiiENSOGAP0000000195699.364498.411
ENSG00000055917homo_sapiensENSP0000035437099.81299.718cebus_imitatorENSCCAP0000003847999.718399.6244
ENSG00000055917homo_sapiensENSP0000035437097.744497.2744urocitellus_parryiiENSUPAP0001001140897.744497.2744
ENSG00000055917homo_sapiensENSP0000035437097.838397.2744moschus_moschiferusENSMMSP0000000368194.722594.1765
ENSG00000055917homo_sapiensENSP0000035437054.229353.8534rhinopithecus_roxellanaENSRROP0000004491598.632597.9487
ENSG00000055917homo_sapiensENSP0000035437099.154198.1203mus_pahariMGP_PahariEiJ_P008200198.875497.8444
ENSG00000055917homo_sapiensENSP0000035437098.402398.0263propithecus_coquereliENSPCOP0000001578599.430299.0503
ENSG00000055917homo_sapiensENSP0000035437022.932312.218caenorhabditis_elegansF21H12.5.138.607620.5696
ENSG00000055917homo_sapiensENSP0000035437020.488712.218caenorhabditis_elegansY45F10A.2.143.426325.8964
ENSG00000055917homo_sapiensENSP0000035437020.488712.218caenorhabditis_elegansY73B6BL.38.143.168325.7426
ENSG00000055917homo_sapiensENSP0000035437022.838312.406caenorhabditis_elegansH12I13.4.139.576521.4984
ENSG00000055917homo_sapiensENSP0000035437018.6099.49248caenorhabditis_elegansF18A11.1.140.824720.8247
ENSG00000055917homo_sapiensENSP0000035437018.32719.30451caenorhabditis_elegansB0273.2.140.206220.4124
ENSG00000055917homo_sapiensENSP0000035437020.864710.5263caenorhabditis_elegansF54C9.8.140.144720.2532
ENSG00000055917homo_sapiensENSP0000035437038.157929.1353caenorhabditis_elegansW06B11.2.157.752544.0967
ENSG00000055917homo_sapiensENSP0000035437058.176745.9586drosophila_melanogasterFBpp030582340.378331.8982
ENSG00000055917homo_sapiensENSP0000035437048.402338.9098ciona_intestinalisENSCINP0000000803365.856852.9412
ENSG00000055917homo_sapiensENSP0000035437079.605371.1466petromyzon_marinusENSPMAP0000000779878.425970.0926
ENSG00000055917homo_sapiensENSP0000035437056.578949.906eptatretus_burgeriENSEBUP0000002408670.574462.2509
ENSG00000055917homo_sapiensENSP0000035437073.496264.1917eptatretus_burgeriENSEBUP0000000677477.272767.4901
ENSG00000055917homo_sapiensENSP0000035437091.071485.9962callorhinchus_miliiENSCMIP0000003718579.426275
ENSG00000055917homo_sapiensENSP0000035437095.206891.5414latimeria_chalumnaeENSLACP0000000989684.206280.9643
ENSG00000055917homo_sapiensENSP0000035437093.327187.8759lepisosteus_oculatusENSLOCP0000002125581.260276.5139
ENSG00000055917homo_sapiensENSP0000035437085.620378.2895clupea_harengusENSCHAP0000003472372.705566.4804
ENSG00000055917homo_sapiensENSP0000035437085.902377.6316danio_rerioENSDARP0000008101375.599768.3209
ENSG00000055917homo_sapiensENSP0000035437085.150477.9135carassius_auratusENSCARP0000004192775.249268.8538
ENSG00000055917homo_sapiensENSP0000035437084.398576.8797carassius_auratusENSCARP0000012606421.654219.7251
ENSG00000055917homo_sapiensENSP0000035437085.620377.1617oncorhynchus_kisutchENSOKIP0000506049175.103167.6834
ENSG00000055917homo_sapiensENSP0000035437085.808377.1617oncorhynchus_mykissENSOMYP0000000067675.267967.6834
ENSG00000055917homo_sapiensENSP0000035437085.338377.1617salmo_salarENSSSAP0000005844873.881266.8023
ENSG00000055917homo_sapiensENSP0000035437085.714377.5376salmo_truttaENSSTUP0000010693075.185568.0132
ENSG00000055917homo_sapiensENSP0000035437086.090278.0075fundulus_heteroclitusENSFHEP0000003407970.624563.9938
ENSG00000055917homo_sapiensENSP0000035437080.545172.4624poecilia_reticulataENSPREP0000001017686.916878.1947
ENSG00000055917homo_sapiensENSP0000035437086.560278.3835xiphophorus_maculatusENSXMAP0000002175676.052868.8687
ENSG00000055917homo_sapiensENSP0000035437085.244477.0677oryzias_latipesENSORLP0000003089075.646468.3903
ENSG00000055917homo_sapiensENSP0000035437086.278278.0075cyclopterus_lumpusENSCLMP0000504662876.563869.2243
ENSG00000055917homo_sapiensENSP0000035437078.477470.8647haplochromis_burtoniENSHBUP0000001331873.053465.9668
ENSG00000055917homo_sapiensENSP0000035437086.842178.7594astatotilapia_callipteraENSACLP0000003337975.305668.2967
ENSG00000055917homo_sapiensENSP0000035437083.552675lates_calcariferENSLCAP0001004579074.20766.611
ENSG00000055917homo_sapiensENSP0000035437091.259485.1504xenopus_tropicalisENSXETP0000006701082.218576.7146
ENSG00000055917homo_sapiensENSP0000035437089.473786.6541chrysemys_picta_belliiENSCPBP0000002824584.622281.9556
ENSG00000055917homo_sapiensENSP0000035437096.146693.2331sphenodon_punctatusENSSPUP0000002216697.243394.2966
ENSG00000055917homo_sapiensENSP0000035437097.274494.3609crocodylus_porosusENSCPRP0000500711486.828984.2282
ENSG00000055917homo_sapiensENSP0000035437064.473759.8684laticauda_laticaudataENSLLTP0000002324892.452885.8491
ENSG00000055917homo_sapiensENSP0000035437093.98590.1316notechis_scutatusENSNSUP0000000405795.419891.5076
ENSG00000055917homo_sapiensENSP0000035437095.394791.4474pseudonaja_textilisENSPTXP0000002105086.604183.0205
ENSG00000055917homo_sapiensENSP0000035437097.462494.5489anas_platyrhynchos_platyrhynchosENSAPLP0000001033897.64694.7269
ENSG00000055917homo_sapiensENSP0000035437097.462494.5489gallus_gallusENSGALP0001001071397.462494.5489
ENSG00000055917homo_sapiensENSP0000035437090.037687.218meleagris_gallopavoENSMGAP0000002412990.978288.1292
ENSG00000055917homo_sapiensENSP0000035437097.462494.7368serinus_canariaENSSCAP0000001850697.64694.9153
ENSG00000055917homo_sapiensENSP0000035437097.368494.5489parus_majorENSPMJP0000001653496.461893.6685
ENSG00000055917homo_sapiensENSP0000035437095.958692.4812anolis_carolinensisENSACAP0000002871095.153891.7055
ENSG00000055917homo_sapiensENSP0000035437073.402365.6955neolamprologus_brichardiENSNBRP0000002721684.707275.8134
ENSG00000055917homo_sapiensENSP0000035437095.582791.6353naja_najaENSNNAP0000000861486.997483.4046
ENSG00000055917homo_sapiensENSP0000035437096.428692.9511podarcis_muralisENSPMRP0000001540585.357782.2795
ENSG00000055917homo_sapiensENSP0000035437097.274494.6429geospiza_fortisENSGFOP0000001519797.641595
ENSG00000055917homo_sapiensENSP0000035437097.462494.7368taeniopygia_guttataENSTGUP0000002484094.703292.0548
ENSG00000055917homo_sapiensENSP0000035437088.345981.203erpetoichthys_calabaricusENSECRP0000000227388.345981.203
ENSG00000055917homo_sapiensENSP0000035437085.996278.1955kryptolebias_marmoratusENSKMAP0000002326775.619868.7603
ENSG00000055917homo_sapiensENSP0000035437094.924891.5414salvator_merianaeENSSMRP0000000538795.103691.7137
ENSG00000055917homo_sapiensENSP0000035437085.244476.9737oryzias_javanicusENSOJAP0000004278774.161966.9665
ENSG00000055917homo_sapiensENSP0000035437079.605372.5564amphilophus_citrinellusENSACIP0000001442675.896169.1756
ENSG00000055917homo_sapiensENSP0000035437086.748178.6654amphiprion_perculaENSAPEP0000002813476.092369.0025
ENSG00000055917homo_sapiensENSP0000035437097.086594.1729pelodiscus_sinensisENSPSIP0000001292186.083383.5
ENSG00000055917homo_sapiensENSP0000035437096.992593.985gopherus_evgoodeiENSGEVP0000500800184.798782.1693
ENSG00000055917homo_sapiensENSP0000035437096.898594.0789chelonoidis_abingdoniiENSCABP0000000955397.172594.345
ENSG00000055917homo_sapiensENSP0000035437078.947472.2744seriola_dumeriliENSSDUP0000000234576.852770.3568
ENSG00000055917homo_sapiensENSP0000035437086.184278.0075cottoperca_gobioENSCGOP0000005608375.722568.5384
ENSG00000055917homo_sapiensENSP0000035437097.086594.0789struthio_camelus_australisENSSCUP0000000321885.868783.2086
ENSG00000055917homo_sapiensENSP0000035437097.462494.5489anser_brachyrhynchusENSABRP0000002235694.101691.2886
ENSG00000055917homo_sapiensENSP0000035437086.184276.7857gasterosteus_aculeatusENSGACP0000001276285.620976.2838
ENSG00000055917homo_sapiensENSP0000035437085.526377.2556cynoglossus_semilaevisENSCSEP0000003257875.206667.9339
ENSG00000055917homo_sapiensENSP0000035437086.466278.2895poecilia_formosaENSPFOP0000001932375.970368.7861
ENSG00000055917homo_sapiensENSP0000035437086.372278.9474myripristis_murdjanENSMMDP0000502093175.825169.3069
ENSG00000055917homo_sapiensENSP0000035437097.368494.5489strigops_habroptilaENSSHBP0000501113897.551894.7269
ENSG00000055917homo_sapiensENSP0000035437078.195570.3008amphiprion_ocellarisENSAOCP0000001216375.636468
ENSG00000055917homo_sapiensENSP0000035437096.898593.985terrapene_carolina_triunguisENSTMTP0000000803887.22584.6024
ENSG00000055917homo_sapiensENSP0000035437085.526377.2556hucho_huchoENSHHUP0000003932775.518768.2158
ENSG00000055917homo_sapiensENSP0000035437085.526377.4436hucho_huchoENSHHUP0000004040775.456168.325
ENSG00000055917homo_sapiensENSP0000035437086.184278.2895betta_splendensENSBSLP0000003679475.785168.843
ENSG00000055917homo_sapiensENSP0000035437083.176775.188pygocentrus_nattereriENSPNAP0000000118675.063667.8541
ENSG00000055917homo_sapiensENSP0000035437023.872220.2068ciona_savignyiENSCSAVP0000000780382.200669.5793
ENSG00000055917homo_sapiensENSP0000035437038.627825.3759saccharomyces_cerevisiaeYLL013C46.757730.7167
ENSG00000055917homo_sapiensENSP0000035437029.887216.1654saccharomyces_cerevisiaeYPR042C29.581416
ENSG00000055917homo_sapiensENSP0000035437032.048917.3872saccharomyces_cerevisiaeYJR091C31.255716.9569
ENSG00000055917homo_sapiensENSP0000035437086.654178.6654seriola_lalandi_dorsalisENSSLDP0000000118276.009969.0025
ENSG00000055917homo_sapiensENSP0000035437086.560278.0075labrus_bergyltaENSLBEP0000002704476.241768.7086
ENSG00000055917homo_sapiensENSP0000035437086.842178.7594pundamilia_nyerereiENSPNYP0000003042575.305668.2967
ENSG00000055917homo_sapiensENSP0000035437086.560278.1955mastacembelus_armatusENSMAMP0000000907376.878169.4491
ENSG00000055917homo_sapiensENSP0000035437086.654178.5714stegastes_partitusENSSPAP0000003058976.009968.92
ENSG00000055917homo_sapiensENSP0000035437085.808377.3496oncorhynchus_tshawytschaENSOTSP0000503023675.51768.0728
ENSG00000055917homo_sapiensENSP0000035437078.853470.9586acanthochromis_polyacanthusENSAPOP0000001294185.437976.8839
ENSG00000055917homo_sapiensENSP0000035437097.462494.6429aquila_chrysaetos_chrysaetosENSACCP0002001590197.64694.8211
ENSG00000055917homo_sapiensENSP0000035437086.466278.2895cyprinodon_variegatusENSCVAP0000002078771.207464.4737
ENSG00000055917homo_sapiensENSP0000035437086.936179.5113denticeps_clupeoidesENSDCDP0000006307976.383269.8596
ENSG00000055917homo_sapiensENSP0000035437086.466278.2895larimichthys_croceaENSLCRP0000500800575.348168.2228
ENSG00000055917homo_sapiensENSP0000035437086.842178.6654takifugu_rubripesENSTRUP0000008563876.935969.6919
ENSG00000055917homo_sapiensENSP0000035437089.567786.8421ficedula_albicollisENSFALP0000000184497.543594.5752
ENSG00000055917homo_sapiensENSP000003543706.578956.57895ficedula_albicollisENSFALP0000003216098.591698.5916
ENSG00000055917homo_sapiensENSP0000035437086.278278.1955hippocampus_comesENSHCOP0000002243072.283565.5118
ENSG00000055917homo_sapiensENSP0000035437086.748179.3233cyprinus_carpio_carpioENSCCRP0000005447876.852670.2748
ENSG00000055917homo_sapiensENSP0000035437086.372278.6654cyprinus_carpio_carpioENSCCRP0000013579975.887769.1164
ENSG00000055917homo_sapiensENSP0000035437097.462494.5489coturnix_japonicaENSCJPP0000501336797.64694.7269
ENSG00000055917homo_sapiensENSP0000035437086.466278.2895poecilia_latipinnaENSPLAP0000000088175.970368.7861
ENSG00000055917homo_sapiensENSP0000035437082.988775.5639sinocyclocheilus_grahamiENSSGRP0000009079874.326667.6768
ENSG00000055917homo_sapiensENSP0000035437086.560279.4173sinocyclocheilus_grahamiENSSGRP0000005153076.368270.0663
ENSG00000055917homo_sapiensENSP0000035437086.842178.7594maylandia_zebraENSMZEP0000500097175.428668.4082
ENSG00000055917homo_sapiensENSP0000035437085.996277.8195tetraodon_nigroviridisENSTNIP0000000568877.020269.697
ENSG00000055917homo_sapiensENSP0000035437076.597772.0865paramormyrops_kingsleyaeENSPKIP0000000723686.061280.9926
ENSG00000055917homo_sapiensENSP0000035437087.582.1429scleropages_formosusENSSFOP0001503944276.124371.4636
ENSG00000055917homo_sapiensENSP0000035437089.943682.8947leptobrachium_leishanenseENSLLEP0000001270780.420274.1176
ENSG00000055917homo_sapiensENSP0000035437074.81267.6692oryzias_melastigmaENSOMEP0000000489185.775977.5862

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001501involved_in skeletal system development1IEAHomo_sapiens(9606)Process
GO:0001942involved_in hair follicle development1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding2HDA,IDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol2IBA,IDAHomo_sapiens(9606)Component
GO:0006417involved_in regulation of translation1IEAHomo_sapiens(9606)Process
GO:0007005involved_in mitochondrion organization1IEAHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule2IDA,ISSHomo_sapiens(9606)Component
GO:0010608acts_upstream_of_or_within post-transcriptional regulation of gene expression2IDA,IMPHomo_sapiens(9606)Process
GO:0022904involved_in respiratory electron transport chain1IEAHomo_sapiens(9606)Process
GO:0031965located_in nuclear membrane1IDAHomo_sapiens(9606)Component
GO:0034063involved_in stress granule assembly1IEAHomo_sapiens(9606)Process
GO:0035196involved_in miRNA processing2IBA,IMPHomo_sapiens(9606)Process
GO:0035198enables miRNA binding1IDAHomo_sapiens(9606)Function
GO:0043488involved_in regulation of mRNA stability2IBA,IDAHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IDAHomo_sapiens(9606)Component
GO:0051276involved_in chromosome organization1IEAHomo_sapiens(9606)Process
GO:0051983involved_in regulation of chromosome segregation1IDAHomo_sapiens(9606)Process
GO:0060612involved_in adipose tissue development1IEAHomo_sapiens(9606)Process
GO:0060964involved_in regulation of miRNA-mediated gene silencing1TASHomo_sapiens(9606)Process
GO:0062104enables pumilio-response element binding1IEAHomo_sapiens(9606)Function
GO:0106222enables lncRNA binding1IEAHomo_sapiens(9606)Function
GO:1900246involved_in positive regulation of RIG-I signaling pathway1IDAHomo_sapiens(9606)Process
GO:2000637involved_in positive regulation of miRNA-mediated gene silencing1IMPHomo_sapiens(9606)Process

Expression