Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs snRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000046647 Gene ID 54960 Accession 26044
Symbol GEMIN8 Alias FAM51A1 Full Name gem nuclear organelle associated protein 8
Status Confidence Length 23168 bases Strand Minus strand
Position X : 14006726 - 14029893 RNA binding domain GEMIN8
Summary The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Transcripts

Protein-Protein Interaction (PPI)

Orthologs

Gene Ontology

Expression