RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000041802	Gene ID	55341	Accession	25652
Symbol	LSG1	Alias	NA	Full Name	large 60S subunit nuclear export GTPase 1
Status	Confidence	Length	31401 bases	Strand	Minus strand
Position	3 : 194640791 - 194672191	RNA binding domain	MMR_HSR1
Summary	This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.[provided by RefSeq, Feb 2009]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000265245	MMR_HSR1	PF01926	1.6e-13	1
ENSP00000408264	MMR_HSR1	PF01926	5.8e-13	1

Showing 1 to 2 of 2 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
25173706	Pclap_PMID25173706_Hs_HEK293	HEK293	Katharina Kramer	2014 Oct;11	doi: 10.1038/nmeth.3092.?Epub 2014 Aug 31
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_HeLa	HeLa	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_MCF7	MCF7	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433._Hs.MCF7.ars.	MCF7	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30824702	PtexRIC_PMID30824702_293T_human	293T	Erika C Urdaneta	2019 Mar 1	doi: 10.1038/s41467-019-08942-3
31076284	R.Deep_PMID_31076284_Hs		Maiwen Caudron-Herger	2019 Jul 11	doi: 10.1016/j.molcel.2019.04.018.?Epub 2019 May 7
33235359	RIC_PMID33235359_humanRIC.superset.2021		Fatima Gebauer	2021 Mar	doi: 10.1038/s41576-020-00302-y
33693821	PP.enrichment.RIC_PMID33693821_Hela_human	Hela	Zheng Zhang	2021 Jun 21	doi: 10.1093/nar/gkab156
35427468	qRIC_PMID35427468_293T_human	293T	Carlos Henrique Vieira-Vieira	2022 Jun 2	doi: 10.1016/j.molcel.2022.03.024.?Epub 2022 Apr 14

Showing 1 to 10 of 11 entries

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
LSG1-201	ENST00000265245	3283	658aa	ENSP00000265245
LSG1-202	ENST00000427461	755	178aa	ENSP00000400903
LSG1-203	ENST00000437613	854	285aa	ENSP00000408264
LSG1-204	ENST00000460584	668	No protein	-
LSG1-205	ENST00000461343	428	No protein	-
LSG1-206	ENST00000466391	791	No protein	-
LSG1-207	ENST00000475763	590	No protein	-
LSG1-208	ENST00000480853	539	No protein	-

Showing 1 to 8 of 8 entries

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Gene Model

Click here to download ENSG00000041802's gene model file

ensgID	Trait	pValue	Pubmed ID
No data available in table

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000041802's PPI file

Paralogs

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Search:

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000041802	homo_sapiens	ENSP00000354091	34.5361	20.1031	homo_sapiens	ENSP00000265245	30.5471	17.7812
ENSG00000041802	homo_sapiens	ENSP00000395772	37.1585	16.5756	homo_sapiens	ENSP00000265245	31.003	13.8298
ENSG00000041802	homo_sapiens	ENSP00000362153	29.4118	15.0479	homo_sapiens	ENSP00000265245	32.6748	16.7173
ENSG00000041802	homo_sapiens	ENSP00000365806	35.9143	23.229	homo_sapiens	ENSP00000265245	33.1307	21.4286
ENSG00000041802	homo_sapiens	ENSP00000264230	21.3467	13.3238	homo_sapiens	ENSP00000265245	22.6444	14.1337
ENSG00000041802	homo_sapiens	ENSP00000323047	39.8204	20.9581	homo_sapiens	ENSP00000265245	20.2128	10.6383

Showing 1 to 6 of 6 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000041802	homo_sapiens	ENSP00000265245	97.7204	95.8967	nomascus_leucogenys	ENSNLEP00000010132	97.7204	95.8967
ENSG00000041802	homo_sapiens	ENSP00000265245	98.6322	97.8723	pan_paniscus	ENSPPAP00000012161	98.6322	97.8723
ENSG00000041802	homo_sapiens	ENSP00000265245	98.3283	96.8085	pongo_abelii	ENSPPYP00000016135	98.3283	96.8085
ENSG00000041802	homo_sapiens	ENSP00000265245	98.6322	97.8723	pan_troglodytes	ENSPTRP00000078144	98.6322	97.8723
ENSG00000041802	homo_sapiens	ENSP00000265245	99.3921	98.1763	gorilla_gorilla	ENSGGOP00000000511	99.3921	98.1763
ENSG00000041802	homo_sapiens	ENSP00000265245	75.076	65.1976	ornithorhynchus_anatinus	ENSOANP00000052946	73.9521	64.2216
ENSG00000041802	homo_sapiens	ENSP00000265245	75.9878	64.4377	sarcophilus_harrisii	ENSSHAP00000026560	70.5219	59.8025
ENSG00000041802	homo_sapiens	ENSP00000265245	54.5593	47.1125	notamacropus_eugenii	ENSMEUP00000008259	67.8639	58.6011
ENSG00000041802	homo_sapiens	ENSP00000265245	79.3313	73.4043	choloepus_hoffmanni	ENSCHOP00000000048	80.0613	74.0798
ENSG00000041802	homo_sapiens	ENSP00000265245	91.3374	85.2584	dasypus_novemcinctus	ENSDNOP00000004825	91.4764	85.3881

Showing 1 to 10 of 208 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003924	enables GTPase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005829	is_active_in cytosol	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0000054	involved_in ribosomal subunit export from nucleus	1	IBA	Homo_sapiens(9606)	Process
GO:0005525	enables GTP binding	1	IDA	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005783	located_in endoplasmic reticulum	1	IDA	Homo_sapiens(9606)	Component
GO:0015030	located_in Cajal body	1	IDA	Homo_sapiens(9606)	Component
GO:0015031	involved_in protein transport	1	IEA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016604	located_in nuclear body	1	IDA	Homo_sapiens(9606)	Component

Showing 1 to 10 of 11 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression