RBP Type
Non-canonical_RBPs
Diseases
Disease
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000018510 Gene ID
8540
Accession
327
Symbol
AGPS
Alias
ADAS;ADPS;RCDP3;ADAP-S;ADHAPS;ALDHPSY
Full Name
alkylglycerone phosphate synthase
Status
Confidence
Length
174279 bases
Strand
Plus strand
Position
2 : 177392746 - 177567024
RNA binding domain
N.A.
Summary
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
AGPS-215
ENST00000680705
1849
No protein
-
AGPS-216
ENST00000680770
3044
624aa
ENSP00000505536
AGPS-204
ENST00000637633
2447
629aa
ENSP00000490844
AGPS-207
ENST00000679459
2103
638aa
ENSP00000506137
AGPS-224
ENST00000681752
7556
122aa
ENSP00000504994
AGPS-203
ENST00000460342
2742
No protein
-
AGPS-214
ENST00000680677
1143
No protein
-
AGPS-218
ENST00000680910
1658
No protein
-
AGPS-217
ENST00000680893
7408
251aa
ENSP00000505929
AGPS-220
ENST00000681032
7520
245aa
ENSP00000505205
AGPS-206
ENST00000679421
8603
No protein
-
AGPS-223
ENST00000681565
7784
341aa
ENSP00000505620
AGPS-202
ENST00000409888
815
189aa
ENSP00000386688
AGPS-201
ENST00000264167
7633
658aa
ENSP00000264167
AGPS-205
ENST00000642466
2640
676aa
ENSP00000494433
AGPS-212
ENST00000680155
7318
568aa
ENSP00000505333
AGPS-208
ENST00000679478
7466
568aa
ENSP00000506484
AGPS-222
ENST00000681449
1849
568aa
ENSP00000505342
AGPS-225
ENST00000681891
11009
No protein
-
AGPS-209
ENST00000679639
1118
No protein
-
AGPS-219
ENST00000681028
3257
410aa
ENSP00000506323
AGPS-211
ENST00000680028
8738
No protein
-
AGPS-210
ENST00000679994
7617
568aa
ENSP00000504957
AGPS-213
ENST00000680390
2250
No protein
-
AGPS-221
ENST00000681300
2170
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
2992 Insulin 5.94238606994105E-8 17903298 9885 Echocardiography 1.20879885520644E-5 17903301 45501 Platelet Function Tests 1.8342300E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005739 located_in mitochondrion 1 HDA Homo_sapiens(9606) Component GO:0005777 is_active_in peroxisome 2 IBA,IDA Homo_sapiens(9606) Component GO:0005778 located_in peroxisomal membrane 1 HDA Homo_sapiens(9606) Component GO:0005782 located_in peroxisomal matrix 1 TAS Homo_sapiens(9606) Component GO:0005829 located_in cytosol 1 TAS Homo_sapiens(9606) Component GO:0008609 enables alkylglycerone-phosphate synthase activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0008610 involved_in lipid biosynthetic process 2 IBA,IDA Homo_sapiens(9606) Process GO:0008611 involved_in ether lipid biosynthetic process 2 IEA,ISS Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0071949 enables FAD binding 1 ISS Homo_sapiens(9606) Function
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