RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000010818	Gene ID	3097	Accession	4921
Symbol	HIVEP2	Alias	SHN2;ZAS2;MBP-2;MIBP1;MRD43;ZNF40B;HIV-EP2	Full Name	HIVEP zinc finger 2
Status	Confidence	Length	194897 bases	Strand	Minus strand
Position	6 : 142751469 - 142946365	RNA binding domain	zf-met
Summary	This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000515550	zf-met	PF12874	2.9e-05	1
ENSP00000515551	zf-met	PF12874	2.9e-05	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID

Gene Model

Click here to download ENSG00000010818's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
31742	Erythrocyte Count	8.9720000E-005	-
76028	Rest	1E-6	27126917
95929	Adiponectin	6E-6	24105470
106631	Cataract, Age-Related Nuclear	3E-6	24951543

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000010818's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	1	IBA	Homo_sapiens(9606)	Function
GO:0003677	enables DNA binding	1	TAS	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0006357	involved_in regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function

Expression