RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000009335	Gene ID	9690	Accession	16803
Symbol	UBE3C	Alias	RAUL;HECTH2;NDSMBA;NEDSMBA	Full Name	ubiquitin protein ligase E3C
Status	Confidence	Length	130455 bases	Strand	Plus strand
Position	7 : 157138916 - 157269370	RNA binding domain	N.A.
Summary	Enables ubiquitin protein ligase activity. Involved in protein polyubiquitination. Predicted to be located in nucleus. Predicted to be part of proteasome complex. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
UBE3C-201	ENST00000348165	5214	1083aa	ENSP00000309198
UBE3C-202	ENST00000389103	1626	404aa	ENSP00000373755
UBE3C-203	ENST00000430750	448	56aa	ENSP00000397432
UBE3C-204	ENST00000469336	655	No protein	-
UBE3C-205	ENST00000470408	5197	No protein	-
UBE3C-208	ENST00000497368	776	No protein	-
UBE3C-207	ENST00000494532	543	No protein	-
UBE3C-206	ENST00000474153	450	No protein	-

Gene Model

Click here to download ENSG00000009335's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
80627	Body Mass Index	8E-6	25673413

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000009335's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000209	involved_in protein polyubiquitination	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0000502	part_of proteasome complex	1	IEA	Homo_sapiens(9606)	Component
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0006511	involved_in ubiquitin-dependent protein catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0035519	involved_in protein K29-linked ubiquitination	1	IDA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0070936	involved_in protein K48-linked ubiquitination	1	IDA	Homo_sapiens(9606)	Process

Expression