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Drugs target to HBA1
| Drug name | Drug type | Disease/phenotype | Mechanism of action(MoA) | Phase | Status | Source |
|---|---|---|---|---|---|---|
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 3.0 | Enrolling by invitation | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 2.0 | Recruiting | ClinicalTrials |
| EFAPROXIRAL | Small molecule | metastatic malignant neoplasm | Hemoglobin HbA negative modulator | 3.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 3.0 | Active, not recruiting | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 4.0 | - | FDA,DailyMed |
| VOXELOTOR | Small molecule | acute lung injury | Hemoglobin HbA positive modulator | 2.0 | Recruiting | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 3.0 | Recruiting | ClinicalTrials |
| EFAPROXIRAL | Small molecule | neoplasm | Hemoglobin HbA negative modulator | 3.0 | - | ATC |
| VOXELOTOR | Small molecule | liver disease | Hemoglobin HbA positive modulator | 1.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 2.0 | Terminated | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 4.0 | Not yet recruiting | ClinicalTrials |
| VOXELOTOR | Small molecule | kidney disease | Hemoglobin HbA positive modulator | 1.0 | Completed | ClinicalTrials |
| EFAPROXIRAL | Small molecule | lung cancer | Hemoglobin HbA negative modulator | 3.0 | Withdrawn | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 1.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 2.0 | Not yet recruiting | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 1.0 | Recruiting | ClinicalTrials |
| EFAPROXIRAL | Small molecule | Central Nervous System Neoplasm | Hemoglobin HbA negative modulator | 1.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | idiopathic pulmonary fibrosis | Hemoglobin HbA positive modulator | 2.0 | Terminated | ClinicalTrials |
| EFAPROXIRAL | Small molecule | breast cancer | Hemoglobin HbA negative modulator | 3.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 2.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | idiopathic pulmonary fibrosis | Hemoglobin HbA positive modulator | 2.0 | Completed | ClinicalTrials |
| EFAPROXIRAL | Small molecule | lung cancer | Hemoglobin HbA negative modulator | 2.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 4.0 | Active, not recruiting | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 4.0 | Completed | ClinicalTrials |
| VOXELOTOR | Small molecule | sickle cell anemia | Hemoglobin HbA positive modulator | 3.0 | Completed | ClinicalTrials |