Drugs target to TOP1

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
IRINOTECAN HYDROCHLORIDESmall moleculenoneDNA topoisomerase I inhibitor4['Recruiting', 'Unknown status', 'Recruiting', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Unknown status', 'Recruiting', 'Unknown status', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Active, not recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Withdrawn', 'Recruiting', 'Completed', 'Completed', '-', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Recruiting', 'Withdrawn', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Unknown status', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Completed', 'Recruiting', 'Active, not recruiting', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Withdrawn', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Withdrawn', 'Completed', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Terminated', 'Recruiting', 'Unknown status', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Withdrawn', 'Completed', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Suspended', 'Unknown status', 'Active, not recruiting', 'Completed', '-', 'Recruiting', 'Active, not recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Unknown status', 'Terminated', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Terminated', 'Completed', 'Completed', 'Completed', 'Terminated', 'Recruiting', 'Completed', 'Suspended', 'Completed', 'Terminated', 'Recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Completed', 'Terminated', 'Recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TRASTUZUMAB DERUXTECANAntibodynoneDNA topoisomerase I inhibitor4['Recruiting', 'Active, not recruiting', 'Active, not recruiting', '-', 'Recruiting', 'Active, not recruiting', 'Recruiting', '-', 'Recruiting', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Suspended', 'Not yet recruiting', 'Active, not recruiting', 'Suspended', 'Recruiting', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
AR-67Small moleculenoneDNA topoisomerase I inhibitor2['Completed', 'Unknown status', 'Active, not recruiting', 'Completed', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
IRINOTECANSmall moleculenoneDNA topoisomerase I inhibitor4['Not yet recruiting', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Not yet recruiting', 'Unknown status', 'Withdrawn', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Active, not recruiting', 'Recruiting', 'Not yet recruiting', 'Completed', 'Completed', 'Suspended', 'Completed', 'Active, not recruiting', 'Recruiting', 'Terminated', 'Active, not recruiting', 'Recruiting', 'Suspended', 'Completed', 'Recruiting', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Withdrawn', 'Completed', 'Withdrawn', 'Completed', 'Not yet recruiting', 'Active, not recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Completed', '-', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Not yet recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Unknown status', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Unknown status', 'Active, not recruiting', 'Suspended', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Completed', '-', 'Withdrawn', 'Withdrawn', 'Withdrawn', 'Completed', 'Withdrawn', 'Withdrawn', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Not yet recruiting', 'Unknown status', 'Completed', 'Terminated', 'Unknown status', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Not yet recruiting', 'Recruiting', 'Withdrawn', 'Completed', 'Not yet recruiting', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Recruiting', 'Recruiting', 'Terminated', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Terminated', 'Completed', 'Active, not recruiting', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Recruiting', 'Recruiting', 'Withdrawn', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Terminated', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Unknown status', 'Withdrawn', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Unknown status', 'Completed', 'Withdrawn', 'Withdrawn', 'Recruiting', 'Unknown status', 'Active, not recruiting', 'Recruiting', 'Unknown status', 'Completed', 'Active, not recruiting', 'Unknown status', 'Unknown status', 'Completed', 'Recruiting', 'Unknown status', 'Active, not recruiting', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Not yet recruiting', 'Terminated', 'Unknown status', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Terminated', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Not yet recruiting', 'Not yet recruiting', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Unknown status', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Terminated', 'Unknown status', 'Completed', 'Completed', 'Active, not recruiting', 'Unknown status', 'Completed', 'Recruiting', 'Not yet recruiting', 'Unknown status', 'Not yet recruiting', 'Unknown status', 'Active, not recruiting', 'Terminated', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Recruiting', 'Withdrawn', 'Unknown status', 'Terminated', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Not yet recruiting', 'Completed', 'Unknown status', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Completed', 'Not yet recruiting', 'Terminated', 'Not yet recruiting', 'Completed', 'Withdrawn', 'Completed', 'Recruiting', 'Terminated', 'Terminated', 'Completed', 'Unknown status', 'Active, not recruiting', 'Not yet recruiting', 'Terminated', 'Terminated', 'Completed', 'Not yet recruiting', 'Unknown status', 'Terminated', 'Active, not recruiting', 'Withdrawn', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Recruiting', '-', 'Withdrawn', 'Active, not recruiting', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Recruiting', 'Unknown status', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Active, not recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Not yet recruiting', 'Completed', 'Unknown status', 'Active, not recruiting', 'Recruiting', 'Completed', 'Not yet recruiting', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Unknown status', 'Recruiting', 'Recruiting', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Unknown status', 'Recruiting', 'Recruiting', 'Unknown status', 'Withdrawn', 'Suspended', 'Recruiting', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Terminated', 'Withdrawn', 'Completed', 'Completed', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Active, not recruiting', 'Not yet recruiting', 'Unknown status', 'Terminated', 'Completed', 'Recruiting', 'Withdrawn', 'Not yet recruiting', 'Terminated', 'Not yet recruiting', 'Terminated', 'Recruiting', 'Not yet recruiting', 'Completed', 'Unknown status', 'Completed', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Unknown status', 'Completed', 'Active, not recruiting', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Not yet recruiting', 'Recruiting', 'Enrolling by invitation', 'Withdrawn', 'Completed', 'Not yet recruiting', 'Active, not recruiting', 'Withdrawn', 'Recruiting', 'Active, not recruiting', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Terminated', 'Not yet recruiting', 'Unknown status', 'Suspended', 'Recruiting', 'Not yet recruiting', 'Recruiting', 'Not yet recruiting', 'Not yet recruiting', 'Unknown status', 'Recruiting', 'Not yet recruiting', 'Recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Terminated', 'Recruiting', 'Completed', 'Active, not recruiting', 'Unknown status', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Active, not recruiting', 'Recruiting', 'Unknown status', 'Active, not recruiting', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Terminated', 'Active, not recruiting', 'Unknown status', 'Active, not recruiting', 'Active, not recruiting', 'Active, not recruiting', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Not yet recruiting', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Terminated', 'Terminated', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Not yet recruiting', 'Completed', 'Terminated', 'Not yet recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Terminated', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Active, not recruiting', 'Terminated', 'Not yet recruiting', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Not yet recruiting', 'Completed', 'Recruiting', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
RUBITECANSmall moleculenoneDNA topoisomerase I inhibitor3['Unknown status', 'Withdrawn', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Withdrawn']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ETIRINOTECAN PEGOLSmall moleculenoneDNA topoisomerase I inhibitor3['Completed', 'Completed', 'Completed', 'Completed', '-', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
GIMATECANSmall moleculenoneDNA topoisomerase I inhibitor2['Completed', 'Completed', 'Completed', 'Completed', 'Not yet recruiting', 'Completed', 'Not yet recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
DS-1062UnknownnoneDNA topoisomerase I inhibitor3['Active, not recruiting', 'Active, not recruiting', 'Recruiting', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Not yet recruiting', 'Active, not recruiting', 'Recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
SACITUZUMAB GOVITECANAntibodynoneDNA topoisomerase I inhibitor4['-', 'Recruiting', 'Not yet recruiting', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Enrolling by invitation', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', '-', 'Recruiting', 'Recruiting', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Not yet recruiting', 'Completed', 'Recruiting', '-', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Withdrawn', 'Withdrawn', 'Not yet recruiting', 'Active, not recruiting', 'Recruiting']['ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'FDA', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TLC-388Small moleculenoneDNA topoisomerase I inhibitor2['Completed', 'Terminated', 'Completed', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
EXATECANSmall moleculenoneDNA topoisomerase I inhibitor3['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
9-AMINOCAMPTOTHECINSmall moleculenoneDNA topoisomerase I inhibitor2['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
BELOTECANSmall moleculenoneDNA topoisomerase I inhibitor3['Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', '-', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials']
PATRITUMAB DERUXTECANAntibodynoneDNA topoisomerase I inhibitor3['Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
MURELETECANUnknownnoneDNA topoisomerase I inhibitor1['Unknown status']['ClinicalTrials']
IRINOTECAN SUCROSOFATESmall moleculenoneDNA topoisomerase I inhibitor3['Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Withdrawn', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
KARENITECINSmall moleculenoneDNA topoisomerase I inhibitor3['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
BECATECARINSmall moleculenoneDNA topoisomerase I inhibitor3['Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
7-ETHYL-10-HYDROXYCAMPTOTHECINSmall moleculenoneDNA topoisomerase I inhibitor2['Withdrawn', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
CAMPTOTHECIN-20-O-PROPIONATESmall moleculenoneDNA topoisomerase I inhibitor2['Terminated', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
EDOTECARINSmall moleculenoneDNA topoisomerase I inhibitor3['Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
DIFLOMOTECANSmall moleculenoneDNA topoisomerase I inhibitor2['Completed']['ClinicalTrials']
AFELETECANSmall moleculenoneDNA topoisomerase I stabiliser2['Withdrawn']['ClinicalTrials']