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Drugs target to RYR1
| Drug name | Drug type | Disease/phenotype | Mechanism of action(MoA) | Phase | Status | Source |
|---|---|---|---|---|---|---|
| DANTROLENE | Small molecule | drug toxicity | Ryanodine receptor 1 antagonist | 2.0 | Terminated | ClinicalTrials |
| DANTROLENE SODIUM | Small molecule | Fever | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | stroke | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE SODIUM | Small molecule | Wolfram syndrome | Ryanodine receptor 1 antagonist | 1.0 | Active, not recruiting | ClinicalTrials |
| DANTROLENE | Small molecule | multiple sclerosis | Ryanodine receptor 1 antagonist | 1.0 | Recruiting | ClinicalTrials |
| DANTROLENE | Small molecule | Fever | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE SODIUM | Small molecule | Spasticity | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | Spinal cord injury | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE SODIUM | Small molecule | Heat Stroke | Ryanodine receptor 1 antagonist | 2.0 | Completed | ClinicalTrials |
| DANTROLENE SODIUM | Small molecule | drug toxicity | Ryanodine receptor 1 antagonist | 2.0 | Terminated | ClinicalTrials |
| DANTROLENE SODIUM | Small molecule | stroke | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | ventricular tachycardia | Ryanodine receptor 1 antagonist | 2.0 | Recruiting | ClinicalTrials |
| DANTROLENE | Small molecule | Heat Stroke | Ryanodine receptor 1 antagonist | 2.0 | Completed | ClinicalTrials |
| DANTROLENE | Small molecule | cerebral palsy | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | Spasticity | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | Wolfram syndrome | Ryanodine receptor 1 antagonist | 1.0 | Active, not recruiting | ClinicalTrials |
| DANTROLENE SODIUM | Small molecule | cerebral palsy | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE SODIUM | Small molecule | Spinal cord injury | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | multiple sclerosis | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE SODIUM | Small molecule | multiple sclerosis | Ryanodine receptor 1 antagonist | 4.0 | - | DailyMed |
| DANTROLENE | Small molecule | Fever | Ryanodine receptor 1 antagonist | 2.0 | Terminated | ClinicalTrials |
| DANTROLENE | Small molecule | injury | Ryanodine receptor 1 antagonist | 2.0 | Recruiting | ClinicalTrials |