RBPWorld - a comprehensive database of RNA Binding Proteins

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Drugs target to PCSK9

Drug name	Drug type	Disease/phenotype	Mechanism of action(MoA)	Phase	Status	Source
ALIROCUMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	4	['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', '-', 'Not yet recruiting', 'Completed', 'Terminated', 'Recruiting', 'Recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', '-', 'Not yet recruiting', 'Completed', 'Completed', 'Completed', 'Terminated', '-', 'Completed', 'Terminated', 'Withdrawn']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
EVOLOCUMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	4	['Withdrawn', 'Withdrawn', '-', 'Withdrawn', '-', 'Recruiting', 'Recruiting', 'Completed', '-', 'Terminated', 'Active, not recruiting', 'Completed', 'Terminated', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', '-', 'Completed', 'Completed', 'Completed', 'Withdrawn', 'Completed', '-', 'Active, not recruiting', 'Active, not recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Not yet recruiting', 'Recruiting', 'Unknown status', 'Withdrawn', 'Recruiting', 'Not yet recruiting', 'Completed', 'Completed', 'Recruiting']	['ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed,ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
INCLISIRAN	Oligonucleotide	none	PCSK9 mRNA RNAi inhibitor	4	['Completed', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Completed', 'Completed', '-', 'Active, not recruiting']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials']
BOCOCIZUMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	3	['Completed', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ONGERICIMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	3	['Active, not recruiting', 'Recruiting', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Active, not recruiting']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TAFOLECIMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	3	['Recruiting', 'Unknown status', 'Completed', 'Completed', 'Active, not recruiting', 'Recruiting', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
LERODALCIBEP	Protein	none	Subtilisin/kexin type 9 inhibitor	3	['Completed', 'Active, not recruiting', 'Active, not recruiting', 'Active, not recruiting']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
FROVOCIMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	2	['Completed', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
INCLISIRAN SODIUM	Oligonucleotide	none	PCSK9 mRNA rnai inhibitor	4	['-', '-']	['FDA', 'FDA']
RALPANCIZUMAB	Antibody	none	Subtilisin/kexin type 9 inhibitor	1	['Completed']	['ClinicalTrials']