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Drugs target to CDK12
| Drug name | Drug type | Disease/phenotype | Mechanism of action(MoA) | Phase | Status | Source |
|---|---|---|---|---|---|---|
| RONICICLIB | Small molecule | neoplasm | Cyclin-dependent kinase inhibitor | 2.0 | Withdrawn | ClinicalTrials |
| AT-7519 | Small molecule | Mantle cell lymphoma | Cyclin-dependent kinase inhibitor | 2.0 | Completed | ClinicalTrials |
| AT-7519 | Small molecule | chronic lymphocytic leukemia | Cyclin-dependent kinase inhibitor | 2.0 | Completed | ClinicalTrials |
| AZD-5438 | Small molecule | neoplasm | Cyclin-dependent kinase inhibitor | 1.0 | Completed | ClinicalTrials |
| PHA-793887 | Small molecule | neoplasm | Cyclin-dependent kinase inhibitor | 1.0 | Terminated | ClinicalTrials |
| RONICICLIB | Small molecule | non-small cell lung carcinoma | Cyclin-dependent kinase inhibitor | 1.0 | Withdrawn | ClinicalTrials |
| AT-7519 | Small molecule | lymphoma | Cyclin-dependent kinase inhibitor | 1.0 | Completed | ClinicalTrials |
| RONICICLIB | Small molecule | small cell lung carcinoma | Cyclin-dependent kinase inhibitor | 2.0 | Terminated | ClinicalTrials |
| RONICICLIB | Small molecule | small cell lung carcinoma | Cyclin-dependent kinase inhibitor | 1.0 | Terminated | ClinicalTrials |
| AT-7519 | Small molecule | neoplasm | Cyclin-dependent kinase inhibitor | 1.0 | Active, not recruiting | ClinicalTrials |
| AT-7519 | Small molecule | multiple myeloma | Cyclin-dependent kinase inhibitor | 1.0 | Completed | ClinicalTrials |
| RONICICLIB | Small molecule | neoplasm | Cyclin-dependent kinase inhibitor | 1.0 | Completed | ClinicalTrials |