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Drugs target to RPL32
| Drug name | Drug type | Disease/phenotype | Mechanism of action(MoA) | Phase | Status | Source |
|---|---|---|---|---|---|---|
| ATALUREN | Small molecule | epilepsy | 80S Ribosome modulator | 2.0 | Completed | ClinicalTrials |
| ATALUREN | Small molecule | cystic fibrosis | 80S Ribosome modulator | 3.0 | Terminated | ClinicalTrials |
| ELX-02 | Unknown | cystic fibrosis | 80S Ribosome modulator | 2.0 | Completed | ClinicalTrials |
| ELX-02 | Unknown | genetic disorder | 80S Ribosome modulator | 1.0 | Completed | ClinicalTrials |
| MT-3724 | Unknown | non-Hodgkins lymphoma | 80S Ribosome inhibitor | 2.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | Becker muscular dystrophy | 80S Ribosome modulator | 2.0 | Completed | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 3.0 | Terminated | ClinicalTrials |
| MT-3724 | Unknown | diffuse large B-cell lymphoma | 80S Ribosome inhibitor | 2.0 | Terminated | ClinicalTrials |
| MT-3724 | Unknown | chronic lymphocytic leukemia | 80S Ribosome inhibitor | 1.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 3.0 | Completed | ClinicalTrials |
| MT-3724 | Unknown | diffuse large B-cell lymphoma | 80S Ribosome inhibitor | 1.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | cystic fibrosis | 80S Ribosome modulator | 3.0 | Completed | ClinicalTrials |
| ATALUREN | Small molecule | cystic fibrosis | 80S Ribosome modulator | 4.0 | Completed | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 2.0 | Completed | ClinicalTrials |
| ELX-02 | Unknown | cystinosis | 80S Ribosome modulator | 2.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 3.0 | Enrolling by invitation | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 3.0 | Active, not recruiting | ClinicalTrials |
| ATALUREN | Small molecule | aniridia | 80S Ribosome modulator | 2.0 | Withdrawn | ClinicalTrials |
| ATALUREN | Small molecule | aniridia | 80S Ribosome modulator | 2.0 | Completed | ClinicalTrials |
| MT-3724 | Unknown | lymphoid leukemia | 80S Ribosome inhibitor | 1.0 | Withdrawn | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 2.0 | Recruiting | ClinicalTrials |
| ATALUREN | Small molecule | cystic fibrosis | 80S Ribosome modulator | 2.0 | Completed | ClinicalTrials |
| ATALUREN | Small molecule | Duchenne muscular dystrophy | 80S Ribosome modulator | 2.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | Becker muscular dystrophy | 80S Ribosome modulator | 3.0 | Completed | ClinicalTrials |
| ELX-02 | Unknown | Alport syndrome | 80S Ribosome modulator | 2.0 | Recruiting | ClinicalTrials |
| ELX-02 | Unknown | kidney disease | 80S Ribosome modulator | 1.0 | Completed | ClinicalTrials |
| ATALUREN | Small molecule | hemophilia B | 80S Ribosome modulator | 2.0 | Terminated | ClinicalTrials |
| ELX-02 | Unknown | cystic fibrosis | 80S Ribosome modulator | 2.0 | Recruiting | ClinicalTrials |
| ATALUREN | Small molecule | Disorder of amino acid and other organic acid metabolism | 80S Ribosome modulator | 2.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | hemophilia A | 80S Ribosome modulator | 2.0 | Terminated | ClinicalTrials |
| ATALUREN | Small molecule | Becker muscular dystrophy | 80S Ribosome modulator | 2.0 | Terminated | ClinicalTrials |