Drugs target to MDM2

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
SIREMADLINSmall moleculenoneTumour suppressor p53/oncoprotein Mdm2 inhibitor2['Recruiting', 'Withdrawn', 'Recruiting', 'Terminated', 'Recruiting', 'Terminated', 'Not yet recruiting', 'Active, not recruiting', 'Not yet recruiting', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
NAVTEMADLINSmall moleculenoneTumour suppressor p53/oncoprotein Mdm2 inhibitor2['Suspended', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Suspended', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
APG115Small moleculenoneTumour suppressor p53/oncoprotein Mdm2 inhibitor2['Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
IDASANUTLINSmall moleculenoneTumour suppressor p53/oncoprotein Mdm2 inhibitor3['Completed', 'Terminated', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Terminated', 'Recruiting', 'Recruiting', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']