RBPWorld - a comprehensive database of RNA Binding Proteins

Drugs target to ROCK2

Drug name	Drug type	Disease/phenotype	Mechanism of action(MoA)	Phase	Status	Source
NETARSUDIL	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	4.0	-	ATC
FASUDIL	Small molecule	cardiovascular disease	Rho-associated protein kinase inhibitor	3.0	-	ATC
NETARSUDIL	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	4.0	Recruiting	ClinicalTrials
BELUMOSUDIL	Small molecule	diffuse scleroderma	Rho-associated protein kinase 2 inhibitor	2.0	Active, not recruiting	ClinicalTrials
SAR-407899	Small molecule	coronary artery disease	Rho-associated protein kinase inhibitor	2.0	Terminated	ClinicalTrials
BELUMOSUDIL	Small molecule	psoriasis	Rho-associated protein kinase 2 inhibitor	2.0	Completed	ClinicalTrials
SAR-407899	Small molecule	coronary artery disease	Rho-associated protein kinase inhibitor	2.0	Terminated	ClinicalTrials
AT-13148	Small molecule	neoplasm	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
NETARSUDIL	Small molecule	corneal edema	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
BELUMOSUDIL	Small molecule	immune system disease	Rho-associated protein kinase 2 inhibitor	4.0	-	ATC
VEROSUDIL	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	2.0	Unknown status	ClinicalTrials
SAR-407899	Small molecule	chronic kidney disease	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
BELUMOSUDIL	Small molecule	colorectal carcinoma	Rho-associated protein kinase 2 inhibitor	0.5	Recruiting	ClinicalTrials
FASUDIL	Small molecule	Dementia	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
NETARSUDIL	Small molecule	Fuchs endothelial corneal dystrophy	Rho-associated protein kinase inhibitor	0.5	Recruiting	ClinicalTrials
RIPASUDIL HYDROCHLORIDE DIHYDRATE	Small molecule	Fuchs' endothelial dystrophy	Rho-associated protein kinase inhibitor	2.0	Recruiting	ClinicalTrials
BELUMOSUDIL	Small molecule	graft versus host disease	Rho-associated protein kinase 2 inhibitor	2.0	Completed	ClinicalTrials
FASUDIL	Small molecule	cardiovascular disease	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
DE-104	Small molecule	open-angle glaucoma	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
BELUMOSUDIL	Small molecule	idiopathic pulmonary fibrosis	Rho-associated protein kinase 2 inhibitor	2.0	Completed	ClinicalTrials
NETARSUDIL DIMESYLATE	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	4.0	-	DailyMed,FDA
NETARSUDIL	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	4.0	-	DailyMed,FDA
NETARSUDIL	Small molecule	low tension glaucoma	Rho-associated protein kinase inhibitor	4.0	Not yet recruiting	ClinicalTrials
NETARSUDIL	Small molecule	Fuchs endothelial corneal dystrophy	Rho-associated protein kinase inhibitor	3.0	Completed	ClinicalTrials
RIPASUDIL	Small molecule	retinopathy of prematurity	Rho-associated protein kinase inhibitor	1.0	Recruiting	ClinicalTrials
RIPASUDIL	Small molecule	Fuchs endothelial corneal dystrophy	Rho-associated protein kinase inhibitor	4.0	Recruiting	ClinicalTrials
NETARSUDIL	Small molecule	open-angle glaucoma	Rho-associated protein kinase inhibitor	0.5	Recruiting	ClinicalTrials
DE-104	Small molecule	open-angle glaucoma	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
DE-104	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
VEROSUDIL	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
RIPASUDIL	Small molecule	Fuchs endothelial corneal dystrophy	Rho-associated protein kinase inhibitor	3.0	Recruiting	ClinicalTrials
SAR-407899	Small molecule	erectile dysfunction	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
NETARSUDIL	Small molecule	Fuchs' endothelial dystrophy	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
FASUDIL	Small molecule	amyotrophic lateral sclerosis	Rho-associated protein kinase inhibitor	2.0	Active, not recruiting	ClinicalTrials
FASUDIL	Small molecule	retinal vein occlusion	Rho-associated protein kinase inhibitor	2.0	Unknown status	ClinicalTrials
NETARSUDIL	Small molecule	open-angle glaucoma	Rho-associated protein kinase inhibitor	4.0	-	DailyMed,FDA
NETARSUDIL	Small molecule	Fuchs endothelial corneal dystrophy	Rho-associated protein kinase inhibitor	2.0	Terminated	ClinicalTrials
AMA0076	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
FASUDIL	Small molecule	internal carotid artery stenosis	Rho-associated protein kinase inhibitor	2.0	Terminated	ClinicalTrials
RIPASUDIL	Small molecule	corneal edema	Rho-associated protein kinase inhibitor	3.0	Recruiting	ClinicalTrials
FASUDIL	Small molecule	amyotrophic lateral sclerosis	Rho-associated protein kinase inhibitor	2.0	Unknown status	ClinicalTrials
AMA0076	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
BELUMOSUDIL	Small molecule	psoriasis vulgaris	Rho-associated protein kinase 2 inhibitor	2.0	Completed	ClinicalTrials
DE-104	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
AMA0076	Small molecule	ocular hypertension	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
BELUMOSUDIL	Small molecule	chronic graft versus host disease	Rho-associated protein kinase 2 inhibitor	2.0	Recruiting	ClinicalTrials
FASUDIL	Small molecule	retinopathy of prematurity	Rho-associated protein kinase inhibitor	2.0	Recruiting	ClinicalTrials
BELUMOSUDIL MESYLATE	Small molecule	graft versus host disease	Rho-associated protein kinase inhibitor	4.0	-	FDA
SAR-407899	Small molecule	chronic kidney disease	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
FASUDIL	Small molecule	myocardial infarction	Rho-associated protein kinase inhibitor	4.0	Not yet recruiting	ClinicalTrials
BELUMOSUDIL	Small molecule	graft versus host disease	Rho-associated protein kinase 2 inhibitor	4.0	-	FDA
BELUMOSUDIL	Small molecule	chronic graft versus host disease	Rho-associated protein kinase 2 inhibitor	2.0	Not yet recruiting	ClinicalTrials
FASUDIL	Small molecule	amyotrophic lateral sclerosis	Rho-associated protein kinase inhibitor	2.0	Recruiting	ClinicalTrials
AMA0076	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	1.0	Completed	ClinicalTrials
VEROSUDIL	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
NETARSUDIL DIMESYLATE	Small molecule	open-angle glaucoma	Rho-associated protein kinase inhibitor	4.0	-	FDA,DailyMed
BELUMOSUDIL	Small molecule	liver disease	Rho-associated protein kinase 2 inhibitor	1.0	Completed	ClinicalTrials
RIPASUDIL	Small molecule	glaucoma	Rho-associated protein kinase inhibitor	3.0	-	ATC
RIPASUDIL	Small molecule	Fuchs' endothelial dystrophy	Rho-associated protein kinase inhibitor	2.0	Recruiting	ClinicalTrials
SAR-407899	Small molecule	erectile dysfunction	Rho-associated protein kinase inhibitor	2.0	Completed	ClinicalTrials
BELUMOSUDIL	Small molecule	chronic graft versus host disease	Rho-associated protein kinase 2 inhibitor	2.0	Active, not recruiting	ClinicalTrials

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Drugs target to ROCK2

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