Drugs target to ROCK2

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
BELUMOSUDILSmall moleculenoneRho-associated protein kinase 2 inhibitor4['Completed', '-', 'Active, not recruiting', 'Recruiting', 'Completed', 'Not yet recruiting', 'Recruiting', 'Completed', 'Completed', '-', 'Active, not recruiting', 'Completed']['ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'FDA', 'ClinicalTrials', 'ClinicalTrials']
DE-104Small moleculenoneRho-associated protein kinase inhibitor2['Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
RIPASUDILSmall moleculenoneRho-associated protein kinase inhibitor4['-', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting']['ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
NETARSUDIL DIMESYLATESmall moleculenoneRho-associated protein kinase inhibitor4['-', '-']['FDA,DailyMed', 'DailyMed,FDA']
SAR-407899Small moleculenoneRho-associated protein kinase inhibitor2['Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
AMA0076Small moleculenoneRho-associated protein kinase inhibitor2['Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
FASUDILSmall moleculenoneRho-associated protein kinase inhibitor4['Terminated', 'Active, not recruiting', 'Unknown status', 'Not yet recruiting', 'Recruiting', 'Completed', '-', 'Recruiting', 'Unknown status', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
AT-13148Small moleculenoneRho-associated protein kinase inhibitor1['Completed']['ClinicalTrials']
NETARSUDILSmall moleculenoneRho-associated protein kinase inhibitor4['Completed', '-', 'Not yet recruiting', 'Completed', 'Recruiting', '-', 'Terminated', 'Recruiting', 'Completed', 'Recruiting', '-']['ClinicalTrials', 'DailyMed,FDA', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed,FDA']
VEROSUDILSmall moleculenoneRho-associated protein kinase inhibitor2['Completed', 'Completed', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
BELUMOSUDIL MESYLATESmall moleculenoneRho-associated protein kinase inhibitor4['-']['FDA']
RIPASUDIL HYDROCHLORIDE DIHYDRATESmall moleculenoneRho-associated protein kinase inhibitor2['Recruiting']['ClinicalTrials']