Drugs target to RAF1

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
SORAFENIBSmall moleculenoneSerine/threonine-protein kinase RAF inhibitor4['Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Unknown status', 'Terminated', 'Unknown status', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Recruiting', 'Completed', 'Not yet recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Withdrawn', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Terminated', 'Unknown status', 'Terminated', 'Recruiting', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Unknown status', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Terminated', 'Terminated', 'Completed', 'Active, not recruiting', 'Completed', 'Terminated', 'Withdrawn', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Not yet recruiting', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Active, not recruiting', 'Withdrawn', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Completed', 'Completed', 'Terminated', 'Withdrawn', 'Active, not recruiting', 'Completed', 'Completed', 'Suspended', 'Not yet recruiting', 'Unknown status', 'Completed', 'Recruiting', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Completed', 'Terminated', 'Unknown status', 'Completed', 'Terminated', 'Withdrawn', 'Completed', 'Terminated', 'Completed', 'Suspended', 'Completed', 'Terminated', 'Not yet recruiting', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Recruiting', 'Recruiting', 'Terminated', 'Terminated', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Recruiting', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Enrolling by invitation', 'Terminated', 'Completed', 'Active, not recruiting', 'Withdrawn', 'Unknown status', 'Completed', 'Recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Withdrawn', 'Completed', '-', 'Active, not recruiting', 'Completed', 'Withdrawn', 'Terminated', 'Withdrawn', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Terminated', 'Unknown status', '-', 'Active, not recruiting', 'Completed', 'Not yet recruiting', 'Unknown status', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Terminated', 'Completed', 'Not yet recruiting', 'Active, not recruiting', 'Completed', 'Terminated', '-', 'Terminated', 'Recruiting', 'Unknown status', 'Unknown status', 'Completed', 'Unknown status', 'Completed', 'Enrolling by invitation', 'Completed', 'Completed', 'Unknown status', 'Withdrawn', 'Terminated', 'Completed', 'Enrolling by invitation', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Recruiting', 'Unknown status', 'Terminated', 'Recruiting', 'Terminated', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Terminated', 'Not yet recruiting', 'Unknown status', 'Terminated', 'Recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Terminated', 'Completed', 'Active, not recruiting', 'Terminated', 'Enrolling by invitation', 'Completed', 'Unknown status', 'Terminated', 'Unknown status', 'Completed', 'Withdrawn', 'Completed', 'Completed', 'Suspended', 'Completed', 'Recruiting', 'Unknown status', 'Completed', 'Terminated', 'Completed', 'Unknown status', 'Unknown status', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Terminated', 'Completed', 'Completed', 'Unknown status', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
SORAFENIB TOSYLATESmall moleculenoneSerine/threonine-protein kinase RAF inhibitor4['Completed', 'Completed', 'Recruiting', 'Active, not recruiting', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Unknown status', 'Completed', 'Unknown status', 'Completed', 'Terminated', 'Unknown status', 'Completed', 'Active, not recruiting', '-', 'Completed', 'Active, not recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Not yet recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Unknown status', 'Completed', 'Terminated', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Suspended', 'Unknown status', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Unknown status', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Withdrawn', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Terminated', 'Recruiting', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', '-', 'Completed', 'Completed', 'Completed', 'Terminated', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
REGORAFENIBSmall moleculenoneSerine/threonine-protein kinase RAF inhibitor4['Active, not recruiting', 'Recruiting', 'Terminated', 'Active, not recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Not yet recruiting', 'Completed', 'Terminated', 'Active, not recruiting', 'Recruiting', 'Terminated', 'Recruiting', 'Completed', 'Terminated', 'Completed', 'Unknown status', 'Recruiting', 'Recruiting', '-', 'Terminated', 'Recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Terminated', 'Active, not recruiting', 'Unknown status', 'Not yet recruiting', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Unknown status', 'Completed', 'Terminated', 'Completed', 'Active, not recruiting', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Withdrawn', 'Completed', 'Terminated', 'Terminated', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Active, not recruiting', 'Not yet recruiting', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed', 'Active, not recruiting', 'Recruiting', 'Not yet recruiting', 'Active, not recruiting', 'Terminated', 'Recruiting', 'Terminated', 'Not yet recruiting', 'Completed', 'Terminated', 'Completed', '-', 'Withdrawn', 'Not yet recruiting', 'Recruiting', 'Active, not recruiting', 'Unknown status', 'Active, not recruiting', 'Recruiting', 'Completed', 'Unknown status', 'Completed', 'Not yet recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Terminated', 'Not yet recruiting', 'Active, not recruiting', 'Completed', 'Withdrawn', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
LY-3009120Small moleculenoneSerine/threonine-protein kinase RAF inhibitor1['Terminated', 'Terminated', 'Terminated', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TOVORAFENIBSmall moleculenoneRAF serine/threonine protein kinase inhibitor3['Terminated', 'Completed', 'Recruiting', 'Completed', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Not yet recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
BELVARAFENIBSmall moleculenoneRAF serine/threonine protein kinase inhibitor2['Recruiting', 'Recruiting', 'Recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
XL-281Small moleculenoneSerine/threonine-protein kinase RAF inhibitor1['Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
LXH254Small moleculenoneB-raf/RAF proto-oncogene serine/threonine-protein kinase inhibitor2['Active, not recruiting', 'Active, not recruiting']['ClinicalTrials', 'ClinicalTrials']
ARQ-736Small moleculenoneSerine/threonine-protein kinase RAF inhibitor1['Completed']['ClinicalTrials']